No photo of Jean Scheijen
  • Universiteitssingel50, UNS50

    6229 ER Maastricht

    Netherlands

20082019
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Research Output 2008 2019

Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer

Nokin, M-J., Bellier, J., Durieux, F., Peulen, O., Rademaker, G., Gabriel, M., Monseur, C., Charloteaux, B., Verbeke, L., van Laere, S., Roncarati, P., Herfs, M., Lambert, C., Scheijen, J., Schalkwijk, C., Colige, A., Caers, J., Delvenne, P., Turtoi, A., Castronovo, V. & 1 others, Bellahcene, A., 23 Jan 2019, In : Breast Cancer Research. 21, 19 p., 11.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Methylglyoxal-Derived Advanced Glycation Endproducts Accumulate in Multiple Sclerosis Lesions

Wetzels, S., Vanmierlo, T., Scheijen, J. L. J. M., van Horssen, J., Amor, S., Somers, V., Schalkwijk, C. G., Hendriks, J. J. A. & Wouters, K., 24 Apr 2019, In : Frontiers in Immunology. 10, 9 p., 855.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Relations of advanced glycation endproducts and dicarbonyls with endothelial dysfunction and low-grade inflammation in individuals with end-stage renal disease in the transition to renal replacement therapy: A cross-sectional observational study

Martens, R. J. H., Broers, N. J. H., Canaud, B., Christiaans, M. H. L., Cornelis, T., Gauly, A., Hermans, M. M. H., Konings, C. J. A. M., van Der Sande, F. M., Scheijen, J. L. J. M., Stifft, F., Wirtz, J. J. J. M., Kooman, J. P. & Schalkwijk, C. G., 13 Aug 2019, In : PLOS ONE. 14, 8, 18 p., 0221058.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Higher Plasma Methylglyoxal Levels Are Associated With Incident Cardiovascular Disease and Mortality in Individuals With Type 2 Diabetes

Hanssen, N. M. J., Westerink, J., Scheijen, J. L. J. M., van der Graaf, Y., Stehouwer, C. D. A. & Schalkwijk, C. G., 1 Aug 2018, In : Diabetes Care. 41, 8, p. 1689-1695 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Quercetin, but Not Epicatechin, Decreases Plasma Concentrations of Methylglyoxal in Adults in a Randomized, Double-Blind, Placebo-Controlled, Crossover Trial with Pure Flavonoids

Van den Eynde, M. D. G., Geleijnse, J. M., Scheijen, J. L. J. M., Hanssen, N. M. J., Dower, J. I., Afman, L. A., Stehouwer, C. D. A., Hollman, P. C. H. & Schalkwijk, C. G., Dec 2018, In : Journal of Nutrition. 148, 12, p. 1911-1916 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2017

Disparity in the micronutrient content of diets high or low in advanced glycation end products (AGEs) does not explain changes in insulin sensitivity

Pearce, K., Hatzinikolas, A., Moran, L., de Courten, M. P. J., Forbes, J., Scheijen, J. L. J. M., Schalkwijk, C. G., Walker, K. & de Courten, B., 2017, In : International Journal of Food Sciences and Nutrition. 68, 8, p. 1021-1026 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Higher Plasma Methylglyoxal Levels Are Associated With Incident Cardiovascular Disease in Individuals With Type 1 Diabetes: A 12-Year Follow-up Study

Hanssen, N. M. J., Scheijen, J. L. J. M., Jorsal, A., Parving, H-H., Tarnow, L., Rossing, P., Stehouwer, C. D. A. & Schalkwijk, C. G., 1 Aug 2017, In : Diabetes. 66, 8, p. 2278-2283 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

1969 Downloads (Pure)
Open Access
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Vitreous advanced glycation endproducts and alpha-dicarbonyls in retinal detachment patients with type 2 diabetes mellitus and non-diabetic controls

Fokkens, B. T., Mulder, D. J., Schalkwijk, C. G., Scheijen, J. L., Smit, A. J. & Los, L. I., 6 Mar 2017, In : PLOS ONE. 12, 3, 11 p., e0173379.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2016
16 Citations (Scopus)
8 Citations (Scopus)

Diet low in advanced glycation end products increases insulin sensitivity in healthy overweight individuals: a double-blind, randomized, crossover trial

de Courten, B., de Courten, M. P. J., Soldatos, G., Dougherty, S. L., Straznicky, N., Schlaich, M., Sourris, K. C., Chand, V., Scheijen, J. L. J. M., Kingwell, B. A., Cooper, M. E., Schalkwijk, C. G., Walker, K. Z. & Forbes, J. M., Jun 2016, In : American Journal of Clinical Nutrition. 103, 6, p. 1426-1433

Research output: Contribution to journalArticleAcademicpeer-review

Energy restriction and Roux-en-Y gastric bypass reduce postprandial alpha-dicarbonyl stress in obese women with type 2 diabetes

Maessen, D. E., Hanssen, N. M., Lips, M. A., Scheijen, J. L., van Dijk, K. W., Pijl, H., Stehouwer, C. D. & Schalkwijk, C. G., Sep 2016, In : Diabetologia. 59, 9, p. 2013-2017

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis

Nokin, M-J., Durieux, F., Peixoto, P., Chiavarina, B., Peulen, O., Blomme, A., Turtoi, A., Costanza, B., Smargiasso, N., Baiwir, D., Scheijen, J. L., Schalkwijk, C. G., Leenders, J., De Tullio, P., Bianchi, E., Thiry, M., Uchida, K., Spiegel, D. A., Cochrane, J. R., Hutton, C. A. & 5 others, De Pauw, E., Delvenne, P., Belpomme, D., Castronovo, V. & Bellahcene, A., 19 Oct 2016, In : Elife. 5, e19375.

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

Surface Area of Detachment, Proliferative Vitreoretinopathy, and Pulse Pressure, but not AGEs, are Associated With Retinal Redetachment

Fokkens, B. T., Mulder, D. J., Nugteren, M. B., Schalkwijk, C. G., Scheijen, J. L., Smit, A. J. & Los, L. I., Dec 2016, In : Investigative Ophthalmology & Visual Science. 57, 15, p. 6633-6638

Research output: Contribution to journalArticleAcademicpeer-review

25 Citations (Scopus)

Plasma Advanced Glycation End Products Are Associated With Incident Cardiovascular Events in Individuals With Type 2 Diabetes: A Case-Cohort Study With a Median Follow-up of 10 Years (EPIC-NL)

Hanssen, N. M. J., Beulens, J. W. J., van Dieren, S., Scheijen, J. L. J. M., van der A, D. L., Spijkerman, A. M. W., van der Schouw, Y. T., Stehouwer, C. D. A. & Schalkwijk, C. G., Jan 2015, In : Diabetes. 64, 1, p. 257-265

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

Protein-bound uraemic toxins, dicarbonyl stress and advanced glycation end products in conventional and extended haemodialysis and haemodiafiltration

Cornelis, T., Eloot, S., Vanholder, R., Glorieux, G., van der Sande, F. M., Scheijen, J. L., Leunissen, K. M., Kooman, J. P. & Schalkwijk, C. G., Aug 2015, In : Nephrology Dialysis Transplantation. 30, 8, p. 1395-1402 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

2014
14 Citations (Scopus)

Association of plasma sRAGE, but not esRAGE with lung function impairment in COPD

Gopal, P., Reynaert, N. L., Scheijen, J. L. J. M., Schalkwijk, C. G., Franssen, F. M. E., Wouters, E. F. M. & Rutten, E. P. A., 25 Feb 2014, In : Respiratory Research. 15, 1, 8 p., 24.

Research output: Contribution to journalArticleAcademicpeer-review

40 Citations (Scopus)

Higher levels of advanced glycation endproducts in human carotid atherosclerotic plaques are associated with a rupture-prone phenotype

Hanssen, N. M. J., Wouters, K., Huijberts, M. S., Gijbels, M. J., Sluimer, J. C., Scheijen, J. L. J. M., Heeneman, S., Biessen, E. A. L., Daemen, M. J. A. P., Brownlee, M., de Kleijn, D. P., Stehouwer, C. D. A., Pasterkamp, G. & Schalkwijk, C. G., May 2014, In : European Heart Journal. 35, 17, p. 1137-1146

Research output: Contribution to journalArticleAcademicpeer-review

16 Citations (Scopus)

Plasma advanced glycation end-products and skin autofluorescence are increased in COPD

Gopal, P., Reynaert, N. L., Scheijen, J. L. J. M., Engelen, L., Schalkwijk, C. G., Franssen, F. M. E., Wouters, E. F. M. & Rutten, E. P. A., 1 Jan 2014, In : European Respiratory Journal. 43, 2, p. 430-438

Research output: Contribution to journalArticleAcademicpeer-review

Systemic stiffening of mouse tail tendon is related to dietary advanced glycation end products but not high-fat diet or cholesterol

Eriksen, C., Svensson, R. B., Scheijen, J., Hag, A. M. F., Schalkwijk, C., Praet, S. F. E., Schjerling, P., Kjaer, M., Magnusson, S. P. & Couppe, C., 15 Oct 2014, In : Journal of Applied Physiology. 117, 8, p. 840-847

Research output: Contribution to journalArticleAcademicpeer-review

2013

Plasma levels of advanced glycation endproducts are associated with type 1 diabetes and coronary artery calcification

van Eupen, M. G. A., Schram, M. T., Colhoun, H. M., Scheijen, J. L. J. M., Stehouwer, C. D. A. & Schalkwijk, C. G., 17 Oct 2013, In : Cardiovascular Diabetology. 12, 149.

Research output: Contribution to journalArticleAcademicpeer-review

2012
16 Citations (Scopus)

Effect of Benfotiamine on Advanced Glycation Endproducts and Markers of Endothelial Dysfunction and Inflammation in Diabetic Nephropathy

Alkhalaf, A., Kleefstra, N., Groenier, K. H., Bilo, H. J. G., Gans, R. O. B., Heeringa, P., Scheijen, J. L., Schalkwijk, C. G., Navis, G. J. & Bakker, S. J. L., 6 Jul 2012, In : PLOS ONE. 7, 7, p. e40427

Research output: Contribution to journalArticleAcademicpeer-review

2009
31 Citations (Scopus)
2008
13 Citations (Scopus)

N{epsilon}-(carboxymethyl)lysine during the early development of hypertension

Baumann, M., Stehouwer, C. D. A., Scheijen, J. L. J. M., Heemann, U., Struijker Boudier, H. A. J. & Schalkwijk, C. G., 1 Jan 2008, In : Annals of the New York Academy of Sciences. 1126, p. 201-4

Research output: Contribution to journalArticleAcademicpeer-review