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Research Output

Glyoxalase-1 overexpression partially prevents diabetes-induced impaired arteriogenesis in a rat hindlimb ligation model

Brouwers, O., Yu, L., Niessen, P., Slenter, J., Jaspers, K., Wagenaar, A., Post, M., Miyata, T., Backes, W., Stehouwer, C., Huijberts, M. & Schalkwijk, C., Aug 2016, In : Glycoconjugate Journal. 33, 4, p. 627-630

Research output: Contribution to journalArticleAcademicpeer-review

Glyoxalase-1 overexpression reduces endothelial dysfunction and attenuates early renal impairment in a rat model of diabetes

Brouwers, O., Niessen, P. M. G., Miyata, T., Ostergaard, J. A., Flyvbjerg, A., Peutz-Kootstra, C. J., Sieber, J., Mundel, P. H., Brownlee, M., Janssen, B. J. A., De Mey, J. G. R., Stehouwer, C. D. A. & Schalkwijk, C. G., Jan 2014, In : Diabetologia. 57, 1, p. 224-235

Research output: Contribution to journalArticleAcademicpeer-review

Endogenous formation of Nε(carboxymethyl)lysine is increased in fatty livers and induces inflammatory markers in an in vitro model of hepatic steatosis

Gaens, K. H. J., Niessen, P. M. G., Rensen, S. S., Buurman, W. A., Greve, J. W. M., Driessen, A., Wolfs, M. G. M., Hofker, M. H., Bloemen, J. G., Dejong, C. H., Stehouwer, C. D. A. & Schalkwijk, C. G., Mar 2012, In : Journal of Hepatology. 56, 3, p. 647-655

Research output: Contribution to journalArticleAcademicpeer-review

Overexpression of Glyoxalase-I Reduces Hyperglycemia-induced Levels of Advanced Glycation End Products and Oxidative Stress in Diabetic Rats.

Brouwers, O., Niessen, P. M., Ferreira, I., Miyata, T., Scheffer, P. G., Teerlink, T., Schrauwen, P., Brownlee, M., Stehouwer, C. D. A. & Schalkwijk, C. G., 1 Jan 2011, In : Journal of Biological Chemistry. 286, 2, p. 1374-1380

Research output: Contribution to journalArticleAcademicpeer-review

Hyperglycaemia-induced impairment of endothelium-dependent vasorelaxation in rat mesenteric arteries is mediated by intracellular methylglyoxal levels in a pathway dependent on oxidative stress.

Brouwers, O., Niessen, P. M., Haenen, G. R. M. M., Miyata, T., Brownlee, M., Stehouwer, C. D. A., de Mey, J. G. R. & Schalkwijk, C. G., May 2010, In : Diabetologia. 53, 5, p. 989-1000 12 p.

Research output: Contribution to journalArticleAcademicpeer-review