Disparity in the micronutrient content of diets high or low in advanced glycation end products (AGEs) does not explain changes in insulin sensitivity

Karma Pearce; Alicia Hatzinikolas; Lisa Moran; Maximilian P. J. de Courten; Josephine Forbes; Jean L. J. M. Scheijen; Casper G. Schalkwijk; Karen Walker; Barbora de Courten

doi:10.1080/09637486.2017.1319468

Disparity in the micronutrient content of diets high or low in advanced glycation end products (AGEs) does not explain changes in insulin sensitivity

Karma Pearce^*, Alicia Hatzinikolas, Lisa Moran, Maximilian P. J. de Courten, Josephine Forbes, Jean L. J. M. Scheijen, Casper G. Schalkwijk, Karen Walker, Barbora de Courten

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

We have previously shown that an isoenergetic low advanced glycation end products (AGEs) diet matched for macronutrient content improved insulin sensitivity compared to high AGE diet. Here, we evaluated the differences in micronutrient intake of these two dietary patterns and if they could explain differences in insulin sensitivity. Participants consumed the intervention diets each for 2weeks with 4weeks of habitual dietary intake (washout) in-between. Dietary analysis revealed that the high AGE diet contained greater levels of retinol equivalents (RE) (478.9+151.3g/day versus 329.0+170.0g/day; p.1) therefore are unlikely to explain observed changes in insulin sensitivity. (clinicaltrials.gov:NCT00422253).

Original language	English
Pages (from-to)	1021-1026
Number of pages	6
Journal	International Journal of Food Sciences and Nutrition
Volume	68
Issue number	8
DOIs	https://doi.org/10.1080/09637486.2017.1319468
Publication status	Published - 2017

Keywords

Advanced glycation end products (AGEs)
ageing
chronic disease
lifestyle disease
LIPID-PEROXIDATION
DOUBLE-BLIND
FOODS
GLYCOXIDATION
INDIVIDUALS
DISEASES
STRESS
TRIAL
FAT

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10.1080/09637486.2017.1319468

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Pearce, K., Hatzinikolas, A., Moran, L., de Courten, M. P. J., Forbes, J., Scheijen, J. L. J. M., Schalkwijk, C. G., Walker, K., & de Courten, B. (2017). Disparity in the micronutrient content of diets high or low in advanced glycation end products (AGEs) does not explain changes in insulin sensitivity. International Journal of Food Sciences and Nutrition, 68(8), 1021-1026. https://doi.org/10.1080/09637486.2017.1319468

@article{18fcbd3a33184bbfb1ceeb26ffd302bf,

title = "Disparity in the micronutrient content of diets high or low in advanced glycation end products (AGEs) does not explain changes in insulin sensitivity",

abstract = "We have previously shown that an isoenergetic low advanced glycation end products (AGEs) diet matched for macronutrient content improved insulin sensitivity compared to high AGE diet. Here, we evaluated the differences in micronutrient intake of these two dietary patterns and if they could explain differences in insulin sensitivity. Participants consumed the intervention diets each for 2weeks with 4weeks of habitual dietary intake (washout) in-between. Dietary analysis revealed that the high AGE diet contained greater levels of retinol equivalents (RE) (478.9+151.3g/day versus 329.0+170.0g/day; p.1) therefore are unlikely to explain observed changes in insulin sensitivity. (clinicaltrials.gov:NCT00422253).",

keywords = "Advanced glycation end products (AGEs), ageing, chronic disease, lifestyle disease, LIPID-PEROXIDATION, DOUBLE-BLIND, FOODS, GLYCOXIDATION, INDIVIDUALS, DISEASES, STRESS, TRIAL, FAT",

author = "Karma Pearce and Alicia Hatzinikolas and Lisa Moran and {de Courten}, {Maximilian P. J.} and Josephine Forbes and Scheijen, {Jean L. J. M.} and Schalkwijk, {Casper G.} and Karen Walker and {de Courten}, Barbora",

year = "2017",

doi = "10.1080/09637486.2017.1319468",

language = "English",

volume = "68",

pages = "1021--1026",

journal = "International Journal of Food Sciences and Nutrition",

issn = "0963-7486",

publisher = "Informa Healthcare",

number = "8",

}

Pearce, K, Hatzinikolas, A, Moran, L, de Courten, MPJ, Forbes, J, Scheijen, JLJM , Schalkwijk, CG, Walker, K & de Courten, B 2017, 'Disparity in the micronutrient content of diets high or low in advanced glycation end products (AGEs) does not explain changes in insulin sensitivity', International Journal of Food Sciences and Nutrition, vol. 68, no. 8, pp. 1021-1026. https://doi.org/10.1080/09637486.2017.1319468

Disparity in the micronutrient content of diets high or low in advanced glycation end products (AGEs) does not explain changes in insulin sensitivity. / Pearce, Karma; Hatzinikolas, Alicia; Moran, Lisa et al.
In: International Journal of Food Sciences and Nutrition, Vol. 68, No. 8, 2017, p. 1021-1026.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Disparity in the micronutrient content of diets high or low in advanced glycation end products (AGEs) does not explain changes in insulin sensitivity

AU - Pearce, Karma

AU - Hatzinikolas, Alicia

AU - Moran, Lisa

AU - de Courten, Maximilian P. J.

AU - Forbes, Josephine

AU - Scheijen, Jean L. J. M.

AU - Schalkwijk, Casper G.

AU - Walker, Karen

AU - de Courten, Barbora

PY - 2017

Y1 - 2017

N2 - We have previously shown that an isoenergetic low advanced glycation end products (AGEs) diet matched for macronutrient content improved insulin sensitivity compared to high AGE diet. Here, we evaluated the differences in micronutrient intake of these two dietary patterns and if they could explain differences in insulin sensitivity. Participants consumed the intervention diets each for 2weeks with 4weeks of habitual dietary intake (washout) in-between. Dietary analysis revealed that the high AGE diet contained greater levels of retinol equivalents (RE) (478.9+151.3g/day versus 329.0+170.0g/day; p.1) therefore are unlikely to explain observed changes in insulin sensitivity. (clinicaltrials.gov:NCT00422253).

AB - We have previously shown that an isoenergetic low advanced glycation end products (AGEs) diet matched for macronutrient content improved insulin sensitivity compared to high AGE diet. Here, we evaluated the differences in micronutrient intake of these two dietary patterns and if they could explain differences in insulin sensitivity. Participants consumed the intervention diets each for 2weeks with 4weeks of habitual dietary intake (washout) in-between. Dietary analysis revealed that the high AGE diet contained greater levels of retinol equivalents (RE) (478.9+151.3g/day versus 329.0+170.0g/day; p.1) therefore are unlikely to explain observed changes in insulin sensitivity. (clinicaltrials.gov:NCT00422253).

KW - Advanced glycation end products (AGEs)

KW - ageing

KW - chronic disease

KW - lifestyle disease

KW - LIPID-PEROXIDATION

KW - DOUBLE-BLIND

KW - FOODS

KW - GLYCOXIDATION

KW - INDIVIDUALS

KW - DISEASES

KW - STRESS

KW - TRIAL

KW - FAT

U2 - 10.1080/09637486.2017.1319468

DO - 10.1080/09637486.2017.1319468

M3 - Article

C2 - 28460575

SN - 0963-7486

VL - 68

SP - 1021

EP - 1026

JO - International Journal of Food Sciences and Nutrition

JF - International Journal of Food Sciences and Nutrition

IS - 8

ER -

Disparity in the micronutrient content of diets high or low in advanced glycation end products (AGEs) does not explain changes in insulin sensitivity

Abstract

Keywords

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