Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer

Marie-Julie Nokin, Justine Bellier, Florence Durieux, Olivier Peulen, Gilles Rademaker, Maude Gabriel, Christine Monseur, Benoit Charloteaux, Lieven Verbeke, Steven van Laere, Patrick Roncarati, Michael Herfs, Charles Lambert, Jean Scheijen, Casper Schalkwijk, Alain Colige, Jo Caers, Philippe Delvenne, Andrei Turtoi, Vincent CastronovoAkeila Bellahcene*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number11
Number of pages19
JournalBreast Cancer Research
Volume21
DOIs
Publication statusPublished - 23 Jan 2019

Keywords

  • Breast cancer
  • Methylglyoxal
  • SMAD1
  • Metastasis
  • Carnosine
  • MAPK
  • EPITHELIAL-MESENCHYMAL TRANSITION
  • SIGNALING PATHWAYS
  • TENASCIN-C
  • PROTEIN
  • GROWTH
  • EXPRESSION
  • MECHANISM
  • RECEPTOR
  • BMP

Cite this

Nokin, M-J., Bellier, J., Durieux, F., Peulen, O., Rademaker, G., Gabriel, M., Monseur, C., Charloteaux, B., Verbeke, L., van Laere, S., Roncarati, P., Herfs, M., Lambert, C., Scheijen, J., Schalkwijk, C., Colige, A., Caers, J., Delvenne, P., Turtoi, A., ... Bellahcene, A. (2019). Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer. Breast Cancer Research, 21, [11]. https://doi.org/10.1186/s13058-018-1095-7