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Research Output 1999 2019

2019

Ascorbic acid supplementation improves postprandial glycaemic control and blood pressure in individuals with type 2 diabetes: Findings of a randomized cross-over trial

Mason, S. A., Rasmussen, B., van Loon, L. J. C., Salmon, J. & Wadley, G. D., Mar 2019, In : Diabetes Obesity & Metabolism. 21, 3, p. 674-682 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

A single bout of strenuous exercise overcomes lipid-induced anabolic resistance to protein ingestion in overweight, middle-aged men

Smiles, W. J., Churchward-Venne, T. A., van Loon, L. J. C., Hawley, J. A. & Camera, D. M., Jun 2019, In : Faseb Journal. 33, 6, p. 7009-7017 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Basal and Postprandial Myofibrillar Protein Synthesis Rates Do Not Differ between Lean and Obese Middle-Aged Men

Kouw, I. W. K., van Dijk, J. W., Horstman, A. M. H., Kramer, I. F., Goessens, J. P. B., van Dielen, F. M. H., Verdijk, L. B. & van Loon, L. J. C., Sep 2019, In : Journal of Nutrition. 149, 9, p. 1533-1542 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Blood flow restricted resistance exercise and reductions in oxygen tension attenuate mitochondrial H2O2 emission rates in human skeletal muscle

Petrick, H. L., Pignanelli, C., Barbeau, P-A., Churchward-Venne, T. A., Dennis, K. M. J. H., van Loon, L. J. C., Burr, J. F., Goossens, G. H. & Holloway, G. P., Aug 2019, In : Journal of Physiology. 597, 15, p. 3985-3997 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Coordinated regulation of skeletal muscle mass and metabolic plasticity during recovery from disuse

Kneppers, A., Leermakers, P., Pansters, N., Backx, E., Gosker, H., van Loon, L., Schols, A., Langen, R. & Verdijk, L., Jan 2019, In : Faseb Journal. 33, 1, p. 1288-1298 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Dose-Dependent Increases in Whole-Body Net Protein Balance and Dietary Protein-Derived Amino Acid Incorporation into Myofibrillar Protein During Recovery from Resistance Exercise in Older Men

Holwerda, A. M., Paulussen, K. J. M., Overkamp, M., Goessens, J. P. B., Kramer, I. F., Wodzig, W. K. W. H., Verdijk, L. B. & van Loon, L. J. C., Feb 2019, In : Journal of Nutrition. 149, 2, p. 221-230 10 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Energy expenditure and dietary intake in professional football players in the Dutch Premier League: Implications for nutritional counselling

Brinkmans, N. Y. J., Iedema, N., Plasqui, G., Wouters, L., Saris, W. H. M., van Loon, L. J. C. & van Dijk, J-W., 17 Dec 2019, In : Journal of Sports Sciences. 37, 24, p. 2759-2767 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Exercising to offset muscle mass loss in hemodialysis patients: The disconnect between intention and intervention

McKenna, C. F., Salvador, A. F., Hendriks, F. K., Harris, A. P. Y., van Loon, L. J. C. & Burd, N. A., Jul 2019, In : Seminars in Dialysis. 32, 4, p. 379-385 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Fructose co-ingestion to increase carbohydrate availability in athletes

Fuchs, C. J., Gonzalez, J. T. & van Loon, L. J. C., 2 Jul 2019, In : Journal of Physiology. 597, 14, p. 3549-3560 12 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

High Versus low Dietary Protein Intake and Bone Health in Older Adults: a Systematic Review and Meta-Analysis

Groenendijk, I., den Boeft, L., van Loon, L. J. C. & de Groot, L. C. P. G. M., 2019, In : Computational and Structural Biotechnology Journal. 17, p. 1101-1112 12 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Leucine coingestion augments the muscle protein synthetic response to the ingestion of 15 g of protein following resistance exercise in older men

Holwerda, A. M., Paulussen, K. J. M., Overkamp, M., Goessens, J. P. B., Kramer, I-F., Wodzig, W. K. W. H., Verdijk, L. B., de Groot, L. C. P. G. M. & van Loon, L. J. C., Sep 2019, In : American Journal of Physiology : Endocrinology and Metabolism. 317, 3, p. E473-E482 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Lipotoxicity plays a key role in the development of both insulin resistance and muscle atrophy in patients with type 2 diabetes

Meex, R. C. R., Blaak, E. E. & van Loon, L. J. C., Sep 2019, In : Obesity Reviews. 20, 9, p. 1205-1217 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access

Nandrolone decanoate administration does not attenuate muscle atrophy during a short period of disuse

Horstman, A. M. H., Backx, E. M. P., Smeets, J. S. J., Marzuca-Nassr, G. N., van Kranenburg, J., de Boer, D., Dolmans, J., Snijders, T., Verdijk, L. B., de Groot, L. C. P. G. M. & van Loon, L. J. C., 28 Jan 2019, In : PLOS ONE. 14, 1, p. 1-15 15 p., 0210823.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

No effect of 25-hydroxyvitamin D supplementation on the skeletal muscle transcriptome in vitamin D deficient frail older adults

Hangelbroek, R. W. J., Vaes, A. M. M., Boekschoten, M., Verdijk, L. B., Hooiveld, G. J. E. J., van Loon, L. J. C., de Groot, L. C. P. G. M. & Kersten, S., 28 May 2019, In : BMC Geriatrics. 19, p. 1-8 8 p., 151.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

No effect of beetroot juice supplementation on exercise economy and performance in recreationally active females despite increased torque production

Wickham, K. A., McCarthy, D. G., Pereira, J. M., Cervone, D. T., Verdijk, L. B., van Loon, L. J. C., Power, G. A. & Spriet, L. L., Jan 2019, In : Physiological Reports. 7, 2, 14 p., 13982.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

One Week of Hospitalization Following Elective Hip Surgery Induces Substantial Muscle Atrophy in Older Patients

Kouw, I. W. K., Groen, B. B. L., Smeets, J. S. J., Kramer, I. F., van Kranenburg, J. M. X., Nilwik, R., Geurts, J. A. P., ten Broeke, R. H. M., Poeze, M., van Loon, L. J. C. & Verdijk, L. B., Jan 2019, In : Journal of the American Medical Directors Association. 20, 1, p. 35-42 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

One Week of Step Reduction Lowers Myofibrillar Protein Synthesis Rates in Young Men

Shad, B. J., Thompson, J. L., Holwerda, A. M., Stocks, B., Elhassan, Y. S., Philp, A., Van Loon, L. J. C. & Wallis, G. A., Oct 2019, In : Medicine and Science in Sports and Exercise. 51, 10, p. 2125-2134 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Perioperative nutritional supplementation and skeletal muscle mass in older hip-fracture patients

Kramer, I. F., Blokhuis, T. J., Verdijk, L. B., van Loon, L. J. C. & Poeze, M., Apr 2019, In : Nutrition Reviews. 77, 4, p. 254-266 13 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Protein Intake Falls below 0.6 g center dot kg(-1)center dot d(-1) in Healthy, Older Patients Admitted for Elective Hip or Knee Arthroplasty

Weijzen, M. E. G., Kouw, I. W. K., Verschuren, A. A. J., Muyters, R., Geurts, J. A., Emans, P. J., Geerlings, P., Verdijk, L. B. & van Loon, L. J. C., Mar 2019, In : Journal of Nutrition Health & Aging. 23, 3, p. 299-305 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Protein Supplementation Does Not Augment Adaptations to Endurance Exercise Training

Jonvik, K. L., Paulussen, K. J. M., Danen, S. L., Ceelen, I. J. M., Horstman, A. M., Wardenaar, F. C., Van Loon, L. J. C. & Van Dijk, J-W., Oct 2019, In : Medicine and Science in Sports and Exercise. 51, 10, p. 2041-2049 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Protein supplementation elicits greater gains in maximal oxygen uptake capacity and stimulates lean mass accretion during prolonged endurance training: a double-blind randomized controlled trial

Knuiman, P., van Loon, L. J. C., Wouters, J., Hopman, M. & Mensink, M., Aug 2019, In : American Journal of Clinical Nutrition. 110, 2, p. 508-518 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Sarcopenia is Related to Mortality in the Acutely Hospitalized Geriatric Patient

Sipers, W. M. W. H., de Blois, W., Schols, J. M. G. A., van Loon, L. J. C. & Verdijk, L. B., Feb 2019, In : Journal of Nutrition Health & Aging. 23, 2, p. 128-137 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access

Sucrose but Not Nitrate Ingestion Reduces Strenuous Cycling-induced Intestinal Injury

Jonvik, K. L., Lenaerts, K., Smeets, J. S. J., Kolkman, J. J., Van Loon, L. J. C. & Verdijk, L. B., Mar 2019, In : Medicine and Science in Sports and Exercise. 51, 3, p. 436-444 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The association between 25-hydroxyvitamin D concentration, physical performance and frailty status in older adults

Vaes, A. M. M., Brouwer-Brolsma, E. M., Toussaint, N., de Regt, M., Tieland, M., van Loon, L. J. C. & de Groot, L. C. P. G. M., Apr 2019, In : European Journal of Nutrition. 58, 3, p. 1173-1181 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The effect of minimally invasive surgical aortic valve replacement on postoperative pulmonary and skeletal muscle function

Boujemaa, H., Yilmaz, A., Robic, B., Koppo, K., Claessen, G., Frederix, I., Dendale, P., Voeller, H., van Loon, L. J. C. & Hansen, D., 1 Jun 2019, In : Experimental Physiology. 104, 6, p. 855-865 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

The Impact of Pre-sleep Protein Ingestion on the Skeletal Muscle Adaptive Response to Exercise in Humans: An Update

Snijders, T., Trommelen, J., Kouw, I. W. K., Holwerda, A. M., Verdijk, L. B. & van Loon, L. J. C., 6 Mar 2019, In : Frontiers in nutrition. 6, p. 1-8 8 p., 17.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

The intrinsically labeled protein approach is the preferred method to quantify the release of dietary protein-derived amino acids into the circulation

Trommelen, J., Holwerda, A. M., Nyakayiru, J., Gorissen, S. H. M., Rooyackers, O., Burd, N. A., Boirie, Y. & van Loon, L. J. C., Sep 2019, In : American Journal of Physiology : Endocrinology and Metabolism. 317, 3, p. E433-E434 2 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

The Muscle Protein Synthetic Response to Meal Ingestion Following Resistance-Type Exercise

Trommelen, J., Betz, M. W. & van Loon, L. J. C., Feb 2019, In : Sports Medicine. 49, 2, p. 185-197 13 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

The Muscle Protein Synthetic Response to Whey Protein Ingestion Is Greater in Middle-Aged Women Compared With Men

Horstman, A. M. H., Kouw, I. W. K., van Dijk, J-W., Hamer, H. M., Groen, B. B. L., van Kranenburg, J., Gorissen, S. H. M. & van Loon, L. J. C., Apr 2019, In : Journal of Clinical Endocrinology & Metabolism. 104, 4, p. 994-1004 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Time-dependent regulation of postprandial muscle protein synthesis rates after milk protein ingestion in young men

van Vliet, S., Reals, J. W., Holwerda, A. M., Emmons, R. S., Goessens, J. P., Paluska, S. A., De Lisio, M., van Loon, L. J. C. & Burd, N. A., Dec 2019, In : Journal of Applied Physiology. 127, 6, p. 1792-1801 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

2018

Adipose tissue lipolytic inhibition enhances the glucoregulatory properties of exercise in type 2 diabetes patients

Hansen, D., Verboven, K., van Dijk, J-W., Zorenc, A., Minten, L., Smeets, K., Verdijk, L. B. & van Loon, L. J. C., 1 Jan 2018, In : European Journal of Sport Science. 18, 9, p. 1245-1254 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Age-Associated Impairments in Mitochondrial ADP Sensitivity Contribute to Redox Stress in Senescent Human Skeletal Muscle

Holloway, G. P., Holwerda, A. M., Miotto, P. M., Dirks, M. L., Verdijk, L. B. & van Loon, L. J. C., 13 Mar 2018, In : Cell Reports. 22, 11, p. 2837-2848 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

A novel in vitro model for the assessment of postnatal myonuclear accretion

Kneppers, A., Verdijk, L., de Theije, C., Corten, M., Gielen, E., van Loon, L., Schols, A. & Langen, R., 14 Feb 2018, In : Skeletal Muscle. 8, 13 p., 4.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Arginine does not rescue p.Q188R mutation deleterious effect in classic galactosemia

Haskovic, M., Derks, B., van der Ploeg, L., Trommelen, J., Nyakayiru, J., van Loon, L. J. C., Mackinnon, S., Yue, W. W., Peake, R. W. A., Zha, L., Demirbas, D., Qi, W., Huang, X., Berry, G. T., Achten, J., Bierau, J., Rubio-Gozalbo, M. E. & Coelho, A. I., 26 Nov 2018, In : Orphanet Journal of Rare Diseases. 13, 8 p., 212.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

A single day of bed rest, irrespective of energy balance, does not affect skeletal muscle gene expression or insulin sensitivity

Dirks, M. L., Stephens, F. B., Jackman, S. R., Galera Gordo, J., Machin, D. J., Pulsford, R. M., van Loon, L. J. C. & Wall, B. T., 1 Jun 2018, In : Experimental Physiology. 103, 6, p. 860-875 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Brain tissue plasticity: protein synthesis rates of the human brain

Smeets, J. S. J., Horstman, A. M. H., Schijns, O. E. M. G., Dings, J. T. A., Hoogland, G., Gijsen, A. P., Goessens, J. P. B., Bouwman, F. G., Wodzig, W. K. W. H., Mariman, E. C. & van Loon, L. J. C., Apr 2018, In : Brain. 141, 8 p., 1122.

Research output: Contribution to journalArticleAcademicpeer-review

Cholecalciferol or 25-Hydroxycholecalciferol Supplementation Does Not Affect Muscle Strength and Physical Performance in Prefrail and Frail Older Adults

Vaes, A. M. M., Tieland, M., Toussaint, N., Nilwik, R., Verdijk, L. B., van Loon, L. J. C. & de Groot, L. C. P. G. M., May 2018, In : Journal of Nutrition. 148, 5, p. 712-720 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Daily resistance-type exercise stimulates muscle protein synthesis in vivo in young men

Holwerda, A. M., Paulussen, K. J. M., Overkamp, M., Smeets, J. S. J., Gijsen, A. P., Goessens, J. P. B., Verdijk, L. B. & van Loon, L. J. C., 1 Jan 2018, In : Journal of Applied Physiology. 124, 1, p. 66-75 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Dietary Nitrate and Muscle Function in Humans: Acute versus Chronic Mechanisms Response

Whitfield, J., Heigenhauser, G. J. F., van Loon, L. J. C., Spriet, L. L., Tupling, A. R. & Holloway, G. P., 1 Apr 2018, In : Medicine and Science in Sports and Exercise. 50, 4, p. 875-875 1 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

Differential effects of leucine and leucine-enriched whey protein on skeletal muscle protein synthesis in aged mice

Dijk, F. J., van Dijk, M., Walrand, S., van Loon, L. J. C., van Norren, K. & Luiking, Y. C., Apr 2018, In : Clinical Nutrition ESPEN. 24, p. 127-133 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access