19992019

Research output per year

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Research Output

2008

Protein co-ingestion stimulates muscle protein synthesis during resistance type exercise

Beelen, M., Koopman, R., Gijsen, A. P., Vandereyt, H., Kies, A. K., Kuipers, H., Saris, W. H. & van Loon, L. J., 1 Jan 2008, In : American Journal of Physiology : Endocrinology and Metabolism. 295, 1, p. E70-E77

Research output: Contribution to journalArticleAcademicpeer-review

57 Citations (Scopus)

Proteins, protein hydrolysates, and bioactive peptides in the management of type 2 diabetes.

Kloek, J., Pasupuleti, V. K. & van Loon, L. J. C., 1 Jan 2008, Nutraceuticals, glycemic health, and type 2 diabetes.. Wiley-Blackwell

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

The muscle protein synthetic response to carbohydrate and protein ingestion is not impaired in men with longstanding type 2 diabetes.

Manders, R. J., Koopman, R., Beelen, M., Gijsen, A. P., Wodzig, W. K., Saris, W. H. & van Loon, L. J., 1 Jan 2008, In : Journal of Nutrition. 138, 6, p. 1079-185

Research output: Contribution to journalArticleAcademicpeer-review

21 Citations (Scopus)

The role of membrane fatty-acid transporters in regulating skeletal muscle substrate use during exercise

Pelsers, M. M., Stellingwerff, T. & van Loon, L. J., 1 Jan 2008, In : Sports Medicine. 38, 5, p. 387-99

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)
2007

Application of protein or protein hydrolysates to improve postexercise recovery

van Loon, L. J., 1 Jan 2007, In : International Journal of Sport Nutrition and Exercise Metabolism. 17, S1, p. S104-S117

Research output: Contribution to journalArticleAcademicpeer-review

9 Citations (Scopus)

A single session of resistance exercise induces oxidative damage in untrained men

Rietjens, S. J., Beelen, M., Koopman, R., van Loon, L. J., Bast, A. & Haenen, G. R., 1 Jan 2007, In : Medicine and Science in Sports and Exercise. 39, 12, p. 2145-2151

Research output: Contribution to journalArticleAcademicpeer-review

34 Citations (Scopus)

Carbohydrate supplementation during prolonged cycling exercise spares muscle glycogen but does not affect intramyocellular lipid use

Stellingwerff, T., Boon, H., Gijsen, A. P., Stegen, J. H. C. H., Kuipers, H. & van Loon, L. J. C., 1 Jan 2007, In : Pflugers Archiv-European Journal of Physiology. 454, 4, p. 635-647

Research output: Contribution to journalArticleAcademicpeer-review

39 Citations (Scopus)

Co-ingestion of carbohydrate with protein does not further augment post-exercise muscle protein synthesis

Koopman, R., Beelen, M., Stellingwerff, T., Pennings, B. P. A., Saris, W. H., Kies, A. K., Kuipers, H. & van Loon, L. J., 1 Jan 2007, In : American Journal of Physiology : Endocrinology and Metabolism. 293, 3, p. E833-E842

Research output: Contribution to journalArticleAcademicpeer-review

80 Citations (Scopus)

Exercise training improves glycemic control in long-standing insulin-treated type 2 diabetic patients.

De Feyter, H. M., Praet, S. F., van den Broek, N. M., Kuipers, H., Stehouwer, C. D., Nicolay, K., Prompers, J. J. & van Loon, L. J., 1 Jan 2007, In : Diabetes Care. 30, 10, p. 2511-2513

Research output: Contribution to journalArticleAcademicpeer-review

25 Citations (Scopus)

High-fat/low-carbohydrate diet reduces insulin-stimulated carbohydrate oxidation but stimulates nonoxidative glucose disposal in humans: an important role for skeletal muscle pyruvate dehydrogenase kinase 4

Chokkalingam, K., Jewell, K., Norton, L., Littlewood, J., van Loon, L. J., Mansell, P., Macdonald, I. A. & Tsintzas, K., 1 Jan 2007, In : Journal of Clinical Endocrinology & Metabolism. 92, 1, p. 284-292

Research output: Contribution to journalArticleAcademicpeer-review

38 Citations (Scopus)

Nutritional interventions to promote post-exercise muscle protein synthesis

Koopman, R., Saris, W. H., Wagenmakers, A. J. & van Loon, L. J., 1 Jan 2007, In : Sports Medicine. 37, 10, p. 895-906

Research output: Contribution to journalArticleAcademicpeer-review

59 Citations (Scopus)

Optimizing the therapeutic benefits of exercise in Type 2 diabetes.

Praet, S. F. & van Loon, L. J., 1 Jan 2007, In : Journal of Applied Physiology. 103, 4, p. 1113-1120

Research output: Contribution to journalArticleAcademicpeer-review

63 Citations (Scopus)

Protein and protein hydrolysates in sports nutrition

van Loon, L. J., Kies, A. & Saris, W. H. M., 1 Jan 2007, In : International Journal of Sport Nutrition and Exercise Metabolism. 17, p. S1-S4

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Protein Ingestion Further Augments S6K1 Phosphorylation in Skeletal Muscle Following Resistance Type Exercise in Males

Koopman, R., Pennings, B. P. A., Zorenc, A. H. & van Loon, L. J., 1 Jan 2007, In : Journal of Nutrition. 137, 8, p. 1880-1886

Research output: Contribution to journalArticleAcademicpeer-review

45 Citations (Scopus)

Reduced plasma free fatty acid availability during exercise: effect on gene expression

Tunstall, R. J., McAinch, A. J., Hargreaves, M., van Loon, L. J. & Cameron Smith, D., 1 Jan 2007, In : European Journal of Applied Physiology. 99, 5, p. 485-493

Research output: Contribution to journalArticleAcademicpeer-review

18 Citations (Scopus)
19 Citations (Scopus)
196 Citations (Scopus)

Significant intramyocellular lipid use during prolonged cycling in endurance trained males as assessed by three different methodologies

Stellingwerff, T., Boon, H., Jonkers, R. A., Senden, J. M., Spriet, L. L., Koopman, R. & van Loon, L. J., 1 Jan 2007, In : American Journal of Physiology : Endocrinology and Metabolism. 292, 6, p. E1715-E1723

Research output: Contribution to journalArticleAcademicpeer-review

45 Citations (Scopus)

Skeletal muscle fatty acid transporter protein expression in type 2 diabetes patients compared with overweight, sedentary men and age-matched, endurance-trained cyclists.

Pelsers, M. M., Tsintzas, K., Boon, H., Jewell, K., Norton, L., Luiken, J. J. F. P., Glatz, J. F. & van Loon, L. J., 1 Jan 2007, In : Acta Physiologica. 190, 3, p. 209-219

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Scopus)

Substrate Source Use in Older, Trained Males after Decades of Endurance Training

Boon, H., Jonkers, R. A., Koopman, R., Blaak, E. E., Saris, W. H., Wagenmakers, A. J. & van Loon, L. J., 1 Jan 2007, In : Medicine and Science in Sports and Exercise. 39, 12, p. 2160-2170

Research output: Contribution to journalArticleAcademicpeer-review

9 Citations (Scopus)

Substrate source utilisation in long-term diagnosed type 2 diabetes patients at rest, and during exercise and subsequent recovery

Boon, H., Blaak, E. E., Saris, W. H. M., Keizer, H. A., Wagenmakers, A. J. & van Loon, L. J., 1 Jan 2007, In : Diabetologia. 50, 1, p. 103-112

Research output: Contribution to journalArticleAcademicpeer-review

29 Citations (Scopus)

The effect of moderate alcohol consumption on adiponectin oligomers and muscle oxidative capacity: a human intervention study.

Beulens, J. W., van Loon, L. J., Kok, F. J., Pelsers, M., Bobbert, T., Spranger, J., Helander, A. & Hendriks, H. F., 1 Jan 2007, In : Diabetologia. 50, 7, p. 1388-1392

Research output: Contribution to journalArticleAcademicpeer-review

32 Citations (Scopus)

The effects of exercise training on fat-mass loss in obese patients during energy intake restriction

Hansen, D., Dendale, P., Berger, J., van Loon, L. J. & Meeusen, R., 1 Jan 2007, In : Sports Medicine. 37, 1, p. 31-46

Research output: Contribution to journalArticleAcademicpeer-review

58 Citations (Scopus)

Thermoregulation during Exercise in the Heat : Strategies for Maintaining Health and Performance

Wendt, D., van Loon, L. J. & van Marken Lichtenbelt, W., 1 Jan 2007, In : Sports Medicine. 37, 8, p. 669-682

Research output: Contribution to journalArticleAcademicpeer-review

73 Citations (Scopus)
2006

(31)P MR spectroscopy and in vitro markers of oxidative capacity in type 2 diabetes patients

Praet, S. F., Feyter, H. M., Jonkers, R. A., Nicolay, K., Pul, C. V., Kuipers, H., van Loon, L. J. & Prompers, J. J., 1 Jan 2006, In : Magnetic Resonance Materials in Physics, Biology and Medicine. 19, 6, p. 321-331

Research output: Contribution to journalArticleAcademicpeer-review

Cinnamon supplementation does not improve glycemic control in postmenopausal type 2 diabetes patients

Vanschoonbeek, K., Thomassen, B. J., Senden, J. M., Wodzig, W. K. & van Loon, L. J., 1 Jan 2006, In : Journal of Nutrition. 136, 4, p. 977-980

Research output: Contribution to journalArticleAcademicpeer-review

127 Citations (Scopus)

Co-Ingestion of a Protein Hydrolysate with or without Additional Leucine Effectively Reduces Postprandial Blood Glucose Excursions in Type 2 Diabetic Men

Manders, R. J., Koopman, R., Sluijsmans, W. E. M., van den Berg, R., Verbeek, K., Saris, W. H., Wagenmakers, A. J. & van Loon, L. J., 1 Jan 2006, In : Journal of Nutrition. 136, 5, p. 1294-1299

Research output: Contribution to journalArticleAcademicpeer-review

57 Citations (Scopus)

Co-ingestion of protein and leucine stimulates muscle protein synthesis rates to the same extent in young and elderly lean men

Koopman, R., Verdijk, L. B., Manders, R. J., Gijsen, A. P., Gorselink, M., Pijpers, E., Wagenmakers, A. J. & van Loon, L. J., 1 Jan 2006, In : American Journal of Clinical Nutrition. 84, 3, p. 623-632

Research output: Contribution to journalArticleAcademicpeer-review

105 Citations (Scopus)

Effects of increasing insulin secretion on acute postexercise blood glucose disposal

Kaastra, B., Manders, R. J., van Breda, E., Kies, A., Jeukendrup, A. E., Keizer, H. A., Kuipers, H. & van Loon, L. J., 1 Jan 2006, In : Medicine and Science in Sports and Exercise. 38, 2, p. 268-275

Research output: Contribution to journalArticleAcademicpeer-review

25 Citations (Scopus)

Glycaemic instability is an underestimated problem in Type II diabetes

Praet, S. F. E., Manders, R. J., Meex, R. C. R., Lieverse, A. G., Stehouwer, C. D., Kuipers, H., Keizer, H. A. & van Loon, L. J., 1 Aug 2006, In : Clinical Science. 111, 2, p. 119-126

Research output: Contribution to journalArticleAcademicpeer-review

41 Citations (Scopus)

Increased intramuscular lipid storage in the insulin-resistant and endurance-trained state

van Loon, L. J. & Goodpaster, B. H., 1 Jan 2006, In : Pflugers Archiv-European Journal of Physiology. 451, 5, p. 606-616

Research output: Contribution to journalArticleAcademicpeer-review

114 Citations (Scopus)

Increase in S6K1 phosphorylation in human skeletal muscle following resistance exercise occurs mainly in type II muscle fibers

Koopman, R., Zorenc, A. H. G., Gransier, R. J., Cameron-Smith, D. & van Loon, L. J., 1 Jan 2006, In : American Journal of Physiology : Endocrinology and Metabolism. 290, 6, p. E1245-E1252

Research output: Contribution to journalArticleAcademicpeer-review

110 Citations (Scopus)

Influence of acute exercise on hyperglycemia in insulin-treated type 2 diabetes

Praet, S. F., Manders, R. J., Lieverse, A. G., Kuipers, H., Stehouwer, C. D., Keizer, H. A. & van Loon, L. J., 1 Jan 2006, In : Medicine and Science in Sports and Exercise. 38, 12, p. 2037-2044

Research output: Contribution to journalArticleAcademicpeer-review

37 Citations (Scopus)

Insulin resistance: the role of intramuscular triglyceride and the importance of physical activity

Timmermans, R. J., Saris, W. H. M. & van Loon, L. J., 1 Jan 2006, In : Nederlands Tijdschrift voor Geneeskunde. 150, 3, p. 122-127

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Intramyocellular lipid and glycogen content are reduced following resistance exercise in untrained healthy males

Koopman, R., Manders, R. J., Jonkers, R. A., Hul, G. B. J., Kuipers, H. & van Loon, L. J., 1 Jan 2006, In : European Journal of Applied Physiology. 96, 5, p. 525-534

Research output: Contribution to journalArticleAcademicpeer-review

63 Citations (Scopus)

Lipid metabolism, exercise and insulin action

Bonen, A., Dohm, G. L. & van Loon, L. J., 1 Jan 2006, In : Essays in Biochemistry. 42, p. 47-59

Research output: Contribution to journalArticleAcademicpeer-review

37 Citations (Scopus)

Protein hydrolysate/leucine co-ingestion reduces the prevalence of hyperglycemia in type 2 diabetic patients

Manders, R. J., Praet, S. F. E., Meex, R. C. R., Koopman, R., de Roos, A. L., Wagenmakers, A. J., Saris, W. H. & van Loon, L. J., 1 Jan 2006, In : Diabetes Care. 29, 12, p. 2721-2722

Research output: Contribution to journalArticleAcademicpeer-review

40 Citations (Scopus)

Untreated classical galactosemia patient with mild phenotype

Panis, B., Bakker, J. A., Sels, J. P. J. E., Spaapen, L. J., van Loon, L. J. & Rubio-Gozalbo, M. E., 1 Jan 2006, In : Molecular Genetics and Metabolism. 89, 3, p. 277-279

Research output: Contribution to journalArticleAcademicpeer-review

17 Citations (Scopus)
2005

A single session of resistance exercise enhances insulin sensitivity for at least 24 h in healthy men

Koopman, R., Manders, R. J. F., Zorenc, A. H. G., Hul, G. B. J., Kuipers, H., Keizer, H. A. & van Loon, L. J., 1 Jan 2005, In : European Journal of Applied Physiology. 94, 1-2, p. 180-187

Research output: Contribution to journalArticleAcademicpeer-review

49 Citations (Scopus)

Co-ingestion of a protein hydrolysate and amino acid mixture with carbohydrate improves plasma glucose disposal in patients with type 2 diabetes

Manders, R. J. F., Wagenmakers, A. J. M., Koopman, R., Zorenc, A. H. G., Menheere, P. P., Wyse, D. G., Saris, W. H. & van Loon, L. J., 1 Jan 2005, In : American Journal of Clinical Nutrition. 82, 1, p. 76-83

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
76 Citations (Scopus)
211 Downloads (Pure)

Combined ingestion of protein and free leucine with carbohydrate increases postexercise muscle protein synthesis in vivo in male subjects

Koopman, R., Wagenmakers, A. J. M., Manders, R. J. F., Zorenc, A. H. G., Senden, J. M. G., Gorselink, M., Keizer, H. A. & van Loon, L. J., 1 Jan 2005, In : American Journal of Physiology : Endocrinology and Metabolism. 288, 4, p. E645-653

Research output: Contribution to journalArticleAcademicpeer-review

163 Citations (Scopus)

Dietary considerations for sport and exercise

van Loon, L. J. C. & Saris, W. H. M., 1 Jan 2005, Human nutrition and dietetics. Geissler & Powers (eds.).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Inhibition of adipose tissue lipolysis increases intramuscular lipid and glycogen use in vivo in humans

van Loon, L. J., Thomason-Hughes, M., Constantin-Teodosiu, D., Koopman, R., Greenhaff, P. L., Hardie, D. G., Keizer, H. A., Saris, W. H. & Wagenmakers, A. J. M., 1 Jan 2005, In : American Journal of Physiology : Endocrinology and Metabolism. 289, 3, p. E482-493

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
43 Citations (Scopus)
127 Downloads (Pure)

Inhibition of adipose tissue lipolysis increases intramuscular lipid use in type 2 diabetic patients

van Loon, L. J., Manders, R. J. F., Koopman, R., Kaastra, B., Stegen, J. H. C. H., Gijsen, A. P., Saris, W. H. & Keizer, H. A., 1 Jan 2005, In : Diabetologia. 48, 10, p. 2097-2107

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
31 Citations (Scopus)
150 Downloads (Pure)

Obesitas: invloed van trainingsprogram-ma's

Hansen, D., van Loon, L. J. C. & Meeusen, R., 1 Jan 2005, Jaarboek voor Kinesitherapeuten. Standaard Uitgeverij

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

The effects of exercise and adipose tissue lipolysis on plasma adiponectin concentration and adiponectin receptor expression in human skeletal muscle

Punyadeera-Mylonas, G. H. P. K. C., Zorenc, A. H. G., Koopman, R., McAinch, A. J., Smit, E., Manders, R. J. F., Keizer, H. A., Smith, D. & van Loon, L. J. C., 1 Jan 2005, In : European Journal of Endocrinology. 152, p. 427-436

Research output: Contribution to journalArticleAcademicpeer-review

72 Citations (Scopus)
2004

Combined ingestion of protein and carbohydrate improves protein balance during ultra-endurance exercise

Koopman, R., Pannemans, D. L. E., Jeukendrup, A. E., Gijsen, A. P., Senden, J. M. G., Halliday, D., Saris, W. H., van Loon, L. J. & Wagenmakers, A. J. M., 1 Jan 2004, In : American Journal of Physiology : Endocrinology and Metabolism. 287, 4, p. E712-720

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
93 Citations (Scopus)
245 Downloads (Pure)

Creatine supplementation increases glycogen storage but not GLUT-4 expression in human skeletal muscle

van Loon, L. J., Murphy, R., Oosterlaar, A. M., Smith, D., Hargreaves, M., Wagenmakers, A. J. M. & Snow, R., 1 Jan 2004, In : Clinical Science. 106, 1, p. 99-106

Research output: Contribution to journalArticleAcademicpeer-review

53 Citations (Scopus)

Intramyocellular lipid content in type 2 diabetes patients compared with overweight sedentary men and highly trained endurance athletes

van Loon, L. J., Koopman, R., Manders, R. J. F., van der Weegen, W., van Kranenburg, G. P. J. & Keizer, H. A., 1 Jan 2004, In : American Journal of Physiology : Endocrinology and Metabolism. 287, 3, p. E558-565

Research output: Contribution to journalArticleAcademicpeer-review

113 Citations (Scopus)

Intramyocellular triacylglycerol as a substrate source during exercise

van Loon, L. J., 1 Jan 2004, In : Proceedings of the Nutrition Society. 63, 2, p. 301-307

Research output: Contribution to journalArticleAcademicpeer-review

17 Citations (Scopus)