Lucas van Loon

2025

Daily blood flow restriction does not affect muscle fiber capillarization and satellite cell content during 2 wk of bed rest in healthy young men

Aussieker, T., Fuchs, C. J., Zorenc, A., Verdijk, L. B., van Loon, L. J. C. & Snijders, T., Jan 2025, In: Journal of Applied Physiology. 138, 1, p. 89-98 10 p.

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Repeated passive heat treatment increases muscle tissue capillarization, but does not affect postprandial muscle protein synthesis rates in healthy older adults

Fuchs, C. J., Betz, M. W., Petrick, H. L., Weber, J., Senden, J. M., Hendriks, F. K., Bels, J. L. M., van Loon, L. J. C. & Snijders, T., 1 Jan 2025, In: Journal of Physiology. 603, 1, p. 167-186 20 p.

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Open Access

2024

Access to a pre-sleep protein snack increases daily energy and protein intake in surgical hospitalized patients

Weijzen, M. E. G., Kohlen, M., Monsegue, A., Houtvast, D. C. J., Nyakayiru, J., Beijer, S., Geerlings, P., Verdijk, L. B. & van Loon, L. J. C., 1 May 2024, In: Clinical Nutrition. 43, 5, p. 1073-1078 6 p.

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Open Access

Administration of Free Amino Acids Improves Exogenous Amino Acid Availability when Compared with Intact Protein in Critically Ill Patients: A Randomized Controlled Study

van Gassel, R. J., Weijzen, M. E., Kouw, I. W., Senden, J. M., Wodzig, W. K., Olde Damink, S. W., van de Poll, M. C. & van Loon, L. J., Feb 2024, In: Journal of Nutrition. 154, 2, p. 554-564 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

A Low or High Physical Activity Level Does Not Modulate Prostate Tumor Tissue Protein Synthesis Rates

Houben, L. H. P., Tuytten, T., Holwerda, A. M., Wisanto, E., Senden, J., Wodzig, W. K. W. H., Olde Damink, S. W. M., Beelen, M., Beijer, S., van Renterghem, K. & van Loon, L. J. C., Apr 2024, In: Medicine and Science in Sports and Exercise. 56, 4, p. 635-643 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

A single bout of jumping exercise does not modulate serum markers of bone formation or bone resorption throughout a 24 h period

Hilkens, L., Bons, J., Nyakayiru, J., van Loon, L. J. C. & van Dijk, J.-W., Nov 2024, In: Bone. 188, 117216.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

A single sauna session does not improve postprandial blood glucose handling in individuals with type 2 diabetes mellitus: a cross-over, randomized, controlled trial

Schenaarts, L., Hendriks, F. K., Fuchs, C. J., Sluijsmans, W. E., Snijders, T. & van Loon, L. J., 29 Aug 2024, (E-pub ahead of print) In: Experimental and clinical endocrinology & diabetes.

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Open Access

A Well-Balanced Vegan Diet Does not Compromise Daily Mixed Muscle Protein Synthesis Rates when Compared with an Omnivorous Diet in Active Older Adults: A Randomized Controlled Cross-Over Trial

Domic, J., Pinckaers, P. J., Grootswagers, P., Siebelink, E., Gerdessen, J. C., van Loon, L. J. & de Groot, L. C., 26 Dec 2024, (E-pub ahead of print) In: Journal of Nutrition.

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Open Access

Becoming a World Champion Powerlifter at 71 Years of Age: It Is Never Too Late to Start Exercising

Fuchs, C. J., Trommelen, J., Weijzen, M. E. G., Smeets, J. S. J., van Kranenburg, J., Verdijk, L. B. & van Loon, L. J. C., Jul 2024, In: International Journal of Sport Nutrition and Exercise Metabolism. 34, 4, p. 223-231 9 p.

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Open Access

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Benefits of resistance training are not preserved after cessation of supervised training in prostate cancer patients on androgen deprivation therapy

Houben, L. H. P., Overkamp, M., Senden, J. M. G., van Roermund, J. G. H., de Vries, P., de Laet, K., van der Meer, S., van Loon, L. J. C., Beelen, M. & Beijer, S., 1 Jan 2024, In: European Journal of Sport Science. 24, 1, p. 116-126 11 p.

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Open Access

Coingestion of Collagen With Whey Protein Prevents Postexercise Decline in Plasma Glycine Availability in Recreationally Active Men

Aussieker, T., Janssen, T. A. H., Hermans, W. J. H., Holwerda, A. M., Senden, J. M., van Kranenburg, J. M. X., Goessens, J. P. B., Snijders, T. & van Loon, L. J. C., Jul 2024, In: International Journal of Sport Nutrition and Exercise Metabolism. 34, 4, p. 189-198 10 p.

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Open Access

Collagen Peptide Supplementation during Training Does Not Further Increase Connective Tissue Protein Synthesis Rates

Kirmse, M., Lottmann, T. M., Volk, N. R., de Marées, M., Holwerda, A. M., van Loon, L. J. C. & Platen, P., 1 Dec 2024, In: Medicine and Science in Sports and Exercise. 56, 12, p. 2296-2304 9 p.

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Comparison of intramyocellular lipid metabolism in patients with diabetes and male athletes

Mezincescu, A. M., Rudd, A., Cheyne, L., Horgan, G., Philip, S., Cameron, D., van Loon, L., Whitfield, P., Gribbin, R., Hu, M. K., Delibegovic, M., Fielding, B., Lobley, G., Thies, F., Newby, D. E., Gray, S., Henning, A. & Dawson, D., 1 Dec 2024, In: Nature Communications. 15, 1, 14 p., 3690.

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Open Access

Continuous glucose monitoring in para cyclists: An observational study

Weijer, V., van der Werf, R., van der Haijden, M., Jeukendrup, A., van Loon, L. J. C. & van Dijk, J.-W., Dec 2024, In: European Journal of Sport Science. 24, 12, p. 1809-1819 11 p.

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Open Access

Daily blood flow restriction does not preserve muscle mass and strength during 2 weeks of bed rest

Fuchs, C. J., Hermans, W. J. H., Nyakayiru, J., Weijzen, M. E. G., Smeets, J. S. J., Aussieker, T., Senden, J. M., Wodzig, W. K. H. W., Snijders, T., Verdijk, L. B. & van Loon, L. J. C., 27 Feb 2024, (E-pub ahead of print) In: The Journal of Physiology.

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Open Access

Do Paralympic athletes suffer from brittle bones? Prevalence and risk factors of low bone mineral density in Paralympic athletes

Weijer, V. C. R., van Dijk, J. W., van Dam, L., Risvang, L., Bons, J., Raastad, T., van Loon, L. J. C. & Jonvik, K. L., 1 Jun 2024, In: Bone Reports. 21, 9 p., 101767.

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Open Access

Energy expenditure and dietary intake in professional female football players in the Dutch Women's League: Implications for nutritional counselling

Brinkmans, N., Plasqui, G., van Loon, L. & van Dijk, J.-W., 2024, In: Journal of Sports Sciences. 42, 4, p. 313-322 10 p.

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Open Access

Energy Requirements of Paralympic Athletes: Insights from the Doubly Labeled Water Approach

Weijer, V. C. R., Jonvik, K. L., van Dam, L., Risvang, L., Plasqui, G., Sandbakk, Ø., Raastad, T., van Loon, L. J. C. & van Dijk, J.-W., 1 May 2024, In: Medicine and Science in Sports and Exercise. 56, 5, p. 963-971 9 p.

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Open Access

Graded Replacement of Carbohydrate-Rich Breakfast Products with Dairy Products: Effects on Postprandial Aminoacidemia, Glycemic Control, Bone Metabolism, and Satiety

Hilkens, L., Praster, F., van Overdam, J., Nyakayiru, J., Singh-Povel, C. M., Bons, J., van Loon, L. J. & van Dijk, J.-W., Feb 2024, In: Journal of Nutrition. 154, 2, p. 479-490 12 p.

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Open Access

Higher muscle protein synthesis rates following ingestion of an omnivorous meal compared with an isocaloric and isonitrogenous vegan meal in healthy, older adults

Pinckaers, P. J. M., Domic, J., Petrick, H. L., Holwerda, A. M., Trommelen, J., Hendriks, F. K., Houben, L. H. P., Goessens, J. P. B., van Kranenburg, J. M. X., Senden, J. M., de Groot, L. C. P. G. M., Verdijk, L. B., Snijders, T. & van Loon, L. J. C., Jul 2024, In: The Journal of nutrition. 154, 7, p. 2120-2132 13 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Ingestion of a Whey Plus Collagen Protein Blend Increases Myofibrillar and Muscle Connective Protein Synthesis Rates

Aussieker, T., Kaiser, J., Hermans, W. J. H., Hendriks, F. K., Holwerda, A. M., Senden, J. M., van Kranenburg, J. M. X., Goessens, J. P. B., Braun, U., Baar, K., Snijders, T. & van Loon, L. J. C., 6 Nov 2024, (E-pub ahead of print) In: Medicine and Science in Sports and Exercise. 10.1249/MSS.0000000000003596.

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Open Access

Jumping Exercise Combined With Collagen Supplementation Preserves Bone Mineral Density in Elite Cyclists

Hilkens, L., van Schijndel, N., Weijer, V. C. R., Decroix, L., Bons, J., van Loon, L. J. C. & van Dijk, J.-W., 2024, In: International Journal of Sport Nutrition and Exercise Metabolism. 34, 1, p. 38-47 10 p.

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Open Access

Ketogenic diet but not free-sugar restriction alters glucose tolerance, lipid metabolism, peripheral tissue phenotype, and gut microbiome: RCT

Hengist, A., Davies, R. G., Walhin, J.-P., Buniam, J., Merrell, L. H., Rogers, L., Bradshaw, L., Moreno-Cabañas, A., Rogers, P. J., Brunstrom, J. M., Hodson, L., van Loon, L. J. C., Barton, W., O'Donovan, C., Crispie, F., O'Sullivan, O., Cotter, P. D., Proctor, K., Betts, J. A. & Koumanov, F. & 2 others, Thompson, D. & Gonzalez, J. T., 20 Aug 2024, In: Cell Reports Medicine. 5, 8, 101667.

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Open Access

Measured and predicted resting metabolic rate of Dutch and Norwegian Paralympic athletes

Weijer, V. C. R., Jonvik, K. L., van Dam, L., Risvang, L., Raastad, T., van Loon, L. J. C. & van Dijk, J.-W., 17 May 2024, (E-pub ahead of print) In: Journal of the Academy of Nutrition and Dietetics.

Research output: Contribution to journal › Article › Academic › peer-review

Mitochondrial bioenergetics are not associated with myofibrillar protein synthesis rates

Holwerda, A. M., Dirks, M. L., Barbeau, P.-A., Goessens, J., Gijsen, A., van Loon, L. J. C. & Holloway, G. P., Oct 2024, In: Journal of cachexia, sarcopenia and muscle. 15, 5, p. 1811-1822 12 p.

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Open Access

Muscle fibre satellite cells are located at a greater distance from capillaries in patients with COPD compared with healthy controls

Betz, M. W., De Brandt, J., Aussieker, T., Monsegue, A. P., Houtvast, D. C. J., Gehlert, S., Verdijk, L. B., van Loon, L. J. C., Gosker, H. R., Langen, R. J. C., Derave, W., Burtin, C., Spruit, M. A. & Snijders, T., 30 Sept 2024, In: ERJ Open Research. 10, 5, 00203-2024.

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Open Access

Muscle Mass and Strength Gains Following Resistance Exercise Training in Older Adults 65-75 Years and Older Adults Above 85 Years

Marzuca-Nassr, G. N., Alegría-Molina, A., SanMartín-Calísto, Y., Artigas-Arias, M., Huard, N., Sapunar, J., Salazar, L. A., Verdijk, L. B. & van Loon, L. J. C., Jan 2024, In: International Journal of Sport Nutrition and Exercise Metabolism. 34, 1, p. 11-19 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

One Week of Single Leg Immobilization Lowers Muscle Connective Protein Synthesis Rates in Healthy, Young Adults

Holwerda, A. M., Weijzen, M. E. G., Zorenc, A., Senden, J., Jetten, G. H. J., Houben, L. H. P., Verdijk, L. B. & van Loon, L. J. C., Apr 2024, In: Medicine and Science in Sports and Exercise. 56, 4, p. 612-622 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Post-prandial muscle protein synthesis rates following the ingestion of pea-derived protein do not differ from ingesting an equivalent amount of milk-derived protein in healthy, young males

Pinckaers, P. J. M., Smeets, J. S. J., Kouw, I. W. K., Goessens, J. P. B., Gijsen, A. P. B., de Groot, L. C. P. G. M., Verdijk, L. B., van Loon, L. J. C. & Snijders, T., Apr 2024, In: European Journal of Nutrition. 63, 3, p. 893-904 12 p.

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Open Access

Resistance Exercise Training, a Simple Intervention to Preserve Muscle Mass and Strength in Prostate Cancer Patients on Androgen Deprivation Therapy

Houben, L. H. P., Beelen, M., van Loon, L. J. C. & Beijer, S., 1 Mar 2024, In: International Journal of Sport Nutrition and Exercise Metabolism. 34, 2, p. 122-134 13 p.

Research output: Contribution to journal › Article › Academic › peer-review

Short-term intermittent fasting and energy restriction do not impair rates of muscle protein synthesis: A randomised, controlled dietary intervention

Kouw, I. W. K., Parr, E. B., Wheeler, M. J., Radford, B. E., Hall, R. C., Senden, J. M., Goessens, J. P. B., van Loon, L. J. C. & Hawley, J. A., 1 Nov 2024, In: Clinical Nutrition. 43, 11, p. 174-184 11 p.

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Open Access

The muscle protein synthetic response following corn protein ingestion does not differ from milk protein in healthy, young adults

Pinckaers, P. J. M., Weijzen, M. E. G., Houben, L. H. P., Zorenc, A. H., Kouw, I. W. K., de Groot, L. C. P. G. M., Verdijk, L. B., Snijders, T. & van Loon, L. J. C., 5 Feb 2024, In: Amino Acids. 56, 1, 14 p., 8.

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Open Access

Type II Muscle Fiber Capillarization Is an Important Determinant of Post-Exercise Microvascular Perfusion in Older Adults

Betz, M. W., Hendriks, F. K., Houben, A. J. H. M., Van Den Eynde, M. D. G., Verdijk, L. B., Van Loon, L. J. C. & Snijders, T., 1 Mar 2024, In: Gerontology. 70, 3, p. 290-301 12 p.

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Open Access

Underpowered Studies in Muscle Metabolism Research: Determinants and Considerations

Houtvast, D. C. J., Betz, M. W., Van Hooren, B., Vanbelle, S., Verdijk, L. B., van Loon, L. J. C. & Trommelen, J., Dec 2024, In: Clinical Nutrition ESPEN. 64, p. 334-343 10 p.

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Open Access

“It gave me a sense of achievement and a sense of purpose”—a qualitative study of patient experiences of a virtually supervised exercise program for adults with advanced cancer and cachexia

Bland, K. A., France-Ratcliffe, M., Krishnasamy, M., Nandi, A., Parr, E. B., Martin, P., Cormie, P., van Loon, L. J. C. & Zopf, E. M., 1 May 2024, In: Supportive Care in Cancer. 32, 5, 325.

Research output: Contribution to journal › Article › Academic › peer-review

2023

Acute Ketone Monoester Supplementation Impairs 20-min Time-Trial Performance in Trained Cyclists: A Randomized, Crossover Trial

McCarthy, D. G., Bone, J., Fong, M., Pinckaers, P. J. M., Bostad, W., Richards, D. L., van Loon, L. J. C. & Gibala, M. J., Jul 2023, In: International Journal of Sport Nutrition and Exercise Metabolism. 33, 4, p. 181-188 8 p.

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Open Access

Acute Quark Ingestion Increases Muscle Protein Synthesis Rates at Rest with a Further Increase after Exercise in Young and Older Adult Males in a Parallel-Group Intervention Trial

Hermans, W. J., Fuchs, C. J., Nyakayiru, J., Hendriks, F. K., Houben, L. H., Senden, J. M., van Loon, L. J. & Verdijk, L. B., Jan 2023, In: Journal of Nutrition. 153, 1, p. 66-75 10 p.

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Open Access

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Bone turnover following high-impact exercise is not modulated by collagen supplementation in young men: A randomized cross-over trial

Hilkens, L., Boerboom, M., van Schijndel, N., Bons, J., van Loon, L. J. C. & van Dijk, J. W., 1 May 2023, In: Bone. 170, 1, 8 p., 116705.

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Open Access

Branched-chain ketoacid co-ingestion with protein lowers amino acid oxidation during hemodialysis: A randomized controlled cross-over trial

Hendriks, F. K., Trommelen, J., van der Sande, F. M., van Kranenburg, J. M. X., Kuijpers, J. H. W., Houtvast, D. C. J., Jetten, G. H. J., Goessens, J. P. B., Meex, S. J. R., Kooman, J. P. & van Loon, L. J. C., 1 Aug 2023, In: Clinical Nutrition. 42, 8, p. 1436-1444 9 p.

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Open Access

Collagen Protein Ingestion during Recovery from Exercise Does Not Increase Muscle Connective Protein Synthesis Rates

Aussieker, T., Hilkens, L., Holwerda, A. M., Fuchs, C. J., Houben, L. H. P., Senden, J. M., van Dijk, J.-W., Snijders, T. & van Loon, L. J. C., Oct 2023, In: Medicine and Science in Sports and Exercise. 55, 10, p. 1792-1802 11 p.

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Open Access

Dietary Nitrate and Corresponding Gut Microbiota Prevent Cardiac Dysfunction in Obese Mice

Petrick, H. L., Ogilvie, L. M., Brunetta, H. S., Robinson, A., Kirsh, A. J., Barbeau, P.-A., Handy, R. M., Coyle-Asbil, B., Gianetto-Hill, C., Dennis, K. M. J. H., van Loon, L. J. C., Chabowski, A., Schertzer, J. D., Allen-Vercoe, E., Simpson, J. A. & Holloway, G. P., 1 Jul 2023, In: Diabetes. 72, 7, p. 844-856 13 p.

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Open Access

Dietary nitrate preserves mitochondrial bioenergetics and mitochondrial protein synthesis rates during short-term immobilization in mice

Petrick, H. L., Handy, R. M., Vachon, B., Frangos, S. M., Holwerda, A. M., Gijsen, A. P., Senden, J. M., van Loon, L. J. C. & Holloway, G. P., 1 Jun 2023, (E-pub ahead of print) In: Journal of Physiology. 18 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Eight-hour time-restricted eating does not lower daily myofibrillar protein synthesis rates: A randomized control trial

Parr, E. B., Kouw, I. W. K., Wheeler, M. J., Radford, B. E., Hall, R. C., Senden, J. M., Goessens, J. P. B., van Loon, L. J. C. & Hawley, J. A., Feb 2023, In: Obesity. 31, S1, p. 116-126 11 p.

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Open Access

Energy Expenditure, Body Composition, and Skeletal Muscle Oxidative Capacity in Patients with Myotonic Dystrophy Type 1

Joosten, I. B. T., Fuchs, C. J., Beelen, M., Plasqui, G., Van Loon, L. J. C. & Faber, C. G., 1 Jan 2023, In: Journal of neuromuscular diseases. 10, 4, p. 701-712 12 p.

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Open Access

Intradialytic protein ingestion and exercise do not compromise uremic toxin removal throughout hemodialysis

Hendriks, F. K., Kuijpers, J. H. W., van Kranenburg, J. M. X., Senden, J. M. G., van der Sande, F. M., Kooman, J. P., Meex, S. J. R. & van Loon, L. J. C., Mar 2023, In: Journal of Renal Nutrition. 33, 2, p. 376-385 10 p.

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Open Access

Low Bone Mineral Density and Associated Risk Factors in Elite Cyclists at Different Stages of a Professional Cycling Career

Hilkens, L., van Schijndel, N., Weijer, V., Boerboom, M., van der Burg, E., Peters, V., Kempers, R., Bons, J., van Loon, L. J. C. & van Dijk, J.-W., 1 May 2023, In: Medicine and Science in Sports and Exercise. 55, 5, p. 957-965 9 p.

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Open Access

Muscle fiber type grouping does not change in response to prolonged resistance exercise training in healthy older men

Krakova, D., Holwerda, A. M., Betz, M. W., Lavin, K. M., Bamman, M. M., van Loon, L. J. C., Verdijk, L. B. & Snijders, T., 1 Mar 2023, In: Experimental Gerontology. 173, 1, 9 p., 112083.

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Open Access

Observations of nemaline bodies in muscle biopsies of critically ill patients infected with SARS-CoV-2

Vandenabeele, F., Stevens, S., Snijders, T., Stessel, B., Dubois, J., van Loon, L. J. C., Lambrichts, I. & Agten, A., Oct 2023, In: Microscopy. 72, 5, p. 388–394

Research output: Contribution to journal › Article › Academic › peer-review

Onset of androgen deprivation therapy leads to rapid deterioration of body composition, physical performance, cardiometabolic health and quality-of-life in prostate cancer patients

Overkamp, M., Houben, L. H. P., van der Meer, S., van Roermund, J. G. H., Bos, R., Kokshoorn, A. P. J., Larsen, M. S., van Loon, L. J. C., Beelen, M. & Beijer, S., 2 Nov 2023, In: Scandinavian Journal of Urology. 57, 1-6, p. 60-66 7 p.

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Open Access

Pre-sleep Protein Ingestion Increases Mitochondrial Protein Synthesis Rates During Overnight Recovery from Endurance Exercise: A Randomized Controlled Trial

Trommelen, J., van Lieshout, G. A. A., Pabla, P., Nyakayiru, J., Hendriks, F. K., Senden, J. M., Goessens, J. P. B., van Kranenburg, J. M. X., Gijsen, A. P., Verdijk, L. B., de Groot, L. C. P. G. M. & van Loon, L. J. C., Jul 2023, In: Sports Medicine. 53, 7, p. 1445-1455 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Lucas van Loon

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