19992019

Research output per year

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Research Output

2011

Endocrine responses during overnight recovery from exercise: impact of nutrition and relationships with muscle protein synthesis.

Betts, J. A., Beelen, M., Stokes, K. A., Saris, W. H. & van Loon, L. J. C., Oct 2011, In : International Journal of Sport Nutrition and Exercise Metabolism. 21, 5, p. 398-409 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)
3 Downloads (Pure)

Exercise-induced splanchnic hypoperfusion results in gut dysfunction in healthy men

van Wijck, K., Lenaerts, K., van Loon, L. J. C., Peters, W. H., Buurman, W. A. & Dejong, C. H. C., 21 Jul 2011, In : PLOS ONE. 6, 7, 9 p., 22366.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
66 Citations (Scopus)
144 Downloads (Pure)

Exercising before protein intake allows for greater use of dietary protein-derived amino acids for de novo muscle protein synthesis in both young and elderly men.

Pennings, B., Koopman, R., Beelen, M., Senden, J. M. G., Saris, W. H. & van Loon, L. J. C., 1 Jan 2011, In : American Journal of Clinical Nutrition. 93, 2, p. 322-331

Research output: Contribution to journalArticleAcademicpeer-review

100 Citations (Scopus)

Impact of protein coingestion on muscle protein synthesis during continuous endurance type exercise.

Beelen, M., Zorenc, A., Pennings, B., Senden, J. M. G., Kuipers, H. & van Loon, L. J. C., Jun 2011, In : American Journal of Physiology : Endocrinology and Metabolism. 300, 6, p. E945-E954 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

23 Citations (Scopus)

Intravenous AICAR during hyperinsulinemia induces systemic hemodynamic changes but has no local metabolic effect.

Bosselaar, M., Smits, P., van Loon, L. J. & Tack, C. J., Oct 2011, In : Journal of Clinical Pharmacology. 51, 10, p. 1449-1458 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

10 Citations (Scopus)

Leucine as a pharmaconutrient to prevent and treat sarcopenia and type 2 diabetes

Leenders, M. & van Loon, L. J. C., 1 Jan 2011, In : Nutrition Reviews. 69, 11, p. 675-689

Research output: Contribution to journalArticleAcademicpeer-review

45 Citations (Scopus)

Post-exercise protein synthesis rates are only marginally higher in type I compared with type II muscle fibres following resistance-type exercise.

Koopman, R., Gleeson, B. G., Gijsen, A. P., Groen, B. B. L., Senden, J. M. G., Rennie, M. J. & van Loon, L. J. C., Aug 2011, In : European Journal of Applied Physiology. 111, 8, p. 1871-1878 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
8 Citations (Scopus)
152 Downloads (Pure)

Postprandial hyperglycemia is highly prevalent throughout the day in type 2 diabetes patients

van Dijk, J. W. M., Manders, R. J. F., Hartgens, F., Stehouwer, C. D. A., Praet, S. F. & van Loon, L. J. C., 1 Jan 2011, In : Diabetes Research and Clinical Practice. 93, 1, p. 31-37

Research output: Contribution to journalArticleAcademicpeer-review

24 Citations (Scopus)

Prolonged leucine supplementation does not augment muscle mass or affect glycemic control in elderly type 2 diabetic men.

Leenders, M., Verdijk, L. B., van der Hoeven, L., van Kranenburg, J., Hartgens, F., Wodzig, K. W. H., Saris, W. H. & van Loon, L. J. C., Jun 2011, In : Journal of Nutrition. 141, 6, p. 1070-1076 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

59 Citations (Scopus)

The production of intrinsically labeled milk and meat protein is feasible and provides functional tools for human nutrition research

Pennings, B., Pellikaan, W. F., Senden, J. M. G., van Vuuren, A. M., Sikkema, J. & van Loon, L. J. C., Sep 2011, In : Journal of Dairy Science. 94, 9, p. 4366-4373 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

23 Citations (Scopus)

Whey protein stimulates postprandial muscle protein accretion more effectively than do casein and casein hydrolysate in older men.

Pennings, B., Boirie, Y., Senden, J. M. G., Gijsen, A. P., Kuipers, H. & van Loon, L. J. C., 1 Jan 2011, In : American Journal of Clinical Nutrition. 93, 5, p. 997-1005

Research output: Contribution to journalArticleAcademicpeer-review

211 Citations (Scopus)
2010
40 Citations (Scopus)

Exercise therapy for obesity and type 2 diabetes.

Praet, S. F. E. & van Loon, L. J. C., 1 Jan 2010, Exercise physiology: from a cellular to an integrative approach.. Connes, P., Hue, O. & Perrey, S. (eds.). IOS Press

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Low-intensity exercise reduces the prevalence of hyperglycemia in type 2 diabetes.

Manders, R. J., van Dijk, J. W. M. & van Loon, L. J., 1 Jan 2010, In : Medicine and Science in Sports and Exercise. 42, 2, p. 219-225

Research output: Contribution to journalArticleAcademicpeer-review

70 Citations (Scopus)

Nutritional strategies to promote postexercise recovery

Beelen, M., Burke, L. M., Gibala, M. J. & van Loon, L. J. C., Dec 2010, In : International Journal of Sport Nutrition and Exercise Metabolism. 20, 6, p. 515-532 18 p.

Research output: Contribution to journalArticleAcademicpeer-review

80 Citations (Scopus)

Plasma adipokine and inflammatory marker concentrations are altered in obese, as opposed to non-obese, type 2 diabetes patients.

Hansen, D., Dendale, P., Beelen, M., Jonkers, R. A., Mullens, A., Corluy, L., Meeusen, R. & van Loon, L. J., Jun 2010, In : European Journal of Applied Physiology. 109, 3, p. 397-404 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

46 Citations (Scopus)

Prescription of physical activity is not sufficient to change sedentary behavior and improve glycemic control in type 2 diabetes patients.

Wisse, W., Rookhuizen, M. B., de Kruif, M. D., van Rossum, J., Jordans, I., ten Cate, H., van Loon, L. J. C. & Meesters, E. W., 1 Jan 2010, In : Diabetes Research and Clinical Practice. 88, 2, p. E10-13

Research output: Contribution to journalArticleAcademicpeer-review

16 Citations (Scopus)

Skeletal muscle lipase content and activity in obesity and type 2 diabetes.

Jocken, J. W. E., Moro, C., Goossens, G. H., Hansen, D., Mairal, A., Hesselink, M. K. C., Langin, D., van Loon, L. J. C. & Blaak, E. E., 1 Jan 2010, In : Journal of Clinical Endocrinology & Metabolism. 95, 12, p. 5449-5453

Research output: Contribution to journalArticleAcademicpeer-review

15 Citations (Scopus)

The impact of training modalities on the clinical benefits of exercise intervention in patients with cardiovascular disease risk or type 2 diabetes mellitus

Hansen, D., Dendale, P., van Loon, L. J. C. & Meeusen, R., 1 Jan 2010, In : Sports Medicine. 40, 11, p. 921-940 20 p.

Research output: Contribution to journalArticleAcademicpeer-review

58 Citations (Scopus)

Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans.

Timmons, J. A., Knudsen, S., Rankinen, T., Koch, L. G., Sarzynski, M. A., Jensen, T., Keller, P., Scheele, C., Vollaard, N. B., Nielsen, S., Akerstrom, T., Macdougald, O. A., Jansson, E., Greenhaff, P. L., Tarnopolsky, M. A., van Loon, L. J., Pedersen, B. K., Sundberg, C. J., Wahlestedt, C., Britton, S. L. & 1 others, Bouchard, C., 1 Jan 2010, In : Journal of Applied Physiology. 108, 6, p. 1487-1496

Research output: Contribution to journalArticleAcademicpeer-review

134 Citations (Scopus)
2009

Aging, exercise, and muscle protein metabolism

Koopman, R. & van Loon, L. J. C., 1 Jan 2009, In : Journal of Applied Physiology. 106, 6, p. 2040-2048

Research output: Contribution to journalArticleAcademicpeer-review

153 Citations (Scopus)

Carbohydrate mouth rinsing in the fed state: lack of enhancement of time-trial performance

Beelen, M., Berghuis, J., Bonaparte, B., Ballak, S. B., Jeukendrup, A. E. & van Loon, L. J., 1 Jan 2009, In : International Journal of Sport Nutrition and Exercise Metabolism. 19, 4, p. 400-9

Research output: Contribution to journalArticleAcademicpeer-review

67 Citations (Scopus)

Continuous low- to moderate-intensity exercise training is as effective as moderate- to high-intensity exercise training at lowering blood HbA(1c) in obese type 2 diabetes patients.

Hansen, D., Dendale, P., Jonkers, R. A., Beelen, M., Manders, R. J., Corluy, L., Mullens, A., Berger, J., Meeusen, R. & van Loon, L. J., 1 Jan 2009, In : Diabetologia. 52, 9, p. 1789-1797

Research output: Contribution to journalArticleAcademicpeer-review

76 Citations (Scopus)

Dietary protein digestion and absorption rates and the subsequent postprandial muscle protein synthetic response do not differ between young and elderly men.

Koopman, R., Walrand, S., Beelen, M., Gijsen, A. P., Kies, A. K., Boirie, Y., Saris, W. H. & van Loon, L. J., 1 Jan 2009, In : Journal of Nutrition. 139, 9, p. 1707-1713

Research output: Contribution to journalArticleAcademicpeer-review

70 Citations (Scopus)

Exercise therapy in type 2 diabetes.

Praet, S. F. & van Loon, L. J., 1 Jan 2009, In : Acta Diabetologica. 46, 4, p. 263-278

Research output: Contribution to journalArticleAcademicpeer-review

45 Citations (Scopus)

Ingestion of a protein hydrolysate is accompanied by an accelerated in vivo digestion and absorption rate when compared with its intact protein.

Koopman, R., Crombach, N., Gijsen, A. P., Walrand, S., Fauquant, J., Kies, A. K., Lemosquet, S., Saris, W. H., Boirie, Y. & van Loon, L. J., 1 Jan 2009, In : American Journal of Clinical Nutrition. 90, 1, p. 106-115

Research output: Contribution to journalArticleAcademicpeer-review

120 Citations (Scopus)

Intra-arterial AICA-riboside administration induces NO-dependent vasodilation in vivo in human skeletal muscle.

Bosselaar, M., Boon, H., van Loon, L. J., Broek, P. H., Smits, P. & Tack, C., 1 Jan 2009, In : American Journal of Physiology : Endocrinology and Metabolism. 297, 3, p. E759-E766

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

Long-term leucine supplementation does not increase muscle mass or strength in healthy elderly men

Suzanne Verhoeven, S., Vanschoonbeek, K., Verdijk, L. B., Koopman, R., Wodzig, W. K., Dendale, P. & van Loon, L. J., 1 Jan 2009, In : American Journal of Clinical Nutrition. 89, 5, p. 1468-1475

Research output: Contribution to journalArticleAcademicpeer-review

117 Citations (Scopus)

One-repetition maximum strength test represents a valid means to assess leg strength in vivo in humans.

Verdijk, L. B., van Loon, L., Meijer, K. & Savelberg, H. H., 1 Jan 2009, In : Journal of Sports Sciences. 27, 1, p. 59-68

Research output: Contribution to journalArticleAcademicpeer-review

61 Citations (Scopus)

Poly (ADP-ribose) Polymerase-1-Inhibiting Flavonoids Attenuate Cytokine Release in Blood from Male Patients with Chronic Obstructive Pulmonary Disease or Type 2 Diabetes

Weseler, A. R., Geraets, L., Moonen, H. J., Manders, R. J., van Loon, L. J., Pennings, H. J., Wouters, E. F., Bast, A. & Hageman, G. J., 1 Jan 2009, In : Journal of Nutrition. 139, 5, p. 952-957

Research output: Contribution to journalArticleAcademicpeer-review

24 Citations (Scopus)

Prevalence of daily hyperglycemia in obese type 2 diabetic men compared with that in lean and obese normoglycemic men: effect of consumption of a sucrose-containing beverage.

Manders, R. J., Pennings, B., Beckers, C. P., Aipassa, T. I. & van Loon, L. J., 1 Jan 2009, In : American Journal of Clinical Nutrition. 90, 3, p. 511-518

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)

Protein hydrolysate co-ingestion does not modulate 24 h glycemic control in long-standing type 2 diabetes patients.

Manders, R. J., Praet, S. F., Vikström, M. H., Saris, W. H. & van Loon, L. J., 1 Jan 2009, In : European Journal of Clinical Nutrition. 63, 1, p. 121-126

Research output: Contribution to journalArticleAcademicpeer-review

16 Citations (Scopus)
118 Citations (Scopus)

Reduced glycaemic and insulinaemic responses following isomaltulose ingestion: implications for postprandial substrate use

van Can, J. G., Ijzerman, T. H., van Loon, L. J., Brouns, F. & Blaak, E. E., 1 Jan 2009, In : British Journal of Nutrition. 102, 10, p. 1408-1413

Research output: Contribution to journalArticleAcademicpeer-review

23 Citations (Scopus)

Reduced glycaemic and insulinaemic responses following trehalose ingestion: implications for postprandial substrate use

van Can, J. G., Ijzerman, T. H., van Loon, L. J., Brouns, F. & Blaak, E. E., 1 Jan 2009, In : British Journal of Nutrition. 102, 10, p. 1395-1399

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Resistance exercise increases postprandial muscle protein synthesis in humans

Witard, O. C., Tieland, M., Beelen, M., Tipton, K. D., van Loon, L. J. & Koopman, R., 1 Jan 2009, In : Medicine and Science in Sports and Exercise. 41, 1, p. 144-54

Research output: Contribution to journalArticleAcademicpeer-review

37 Citations (Scopus)
146 Citations (Scopus)

Slowly digestible carbohydrate sources can be used to attenuate the postprandial glycemic response to the ingestion of diabetes-specific enteral formulas.

Vanschoonbeek, K., Lansink, M., van Laere, K. M., Senden, J. M., Verdijk, L. B. & van Loon, L. J., 1 Jan 2009, In : Diabetes Educator. 35, 4, p. 631-640

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Scopus)

The impact of sarcopenia and exercise training on skeletal muscle satellite cells.

Snijders, T., Verdijk, L. B. & van Loon, L. J., 1 Jan 2009, In : Ageing Research Reviews. 8, 4, p. 328-338

Research output: Contribution to journalArticleAcademicpeer-review

106 Citations (Scopus)

The production of intrinsically labeled milk protein provides a functional tool for human nutrition research

van Loon, L. J., Boirie, Y., Gijsen, A. P., Fauquant, J., de Roos, A. L., Kies, A. K., Lemosquet, S., Saris, W. H. & Koopman, R., 1 Jan 2009, In : Journal of Dairy Science. 92, 10, p. 4812-22

Research output: Contribution to journalArticleAcademicpeer-review

37 Citations (Scopus)
2008

Brisk walking compared with an individualised medical fitness programme for patients with type 2 diabetes: a randomised controlled trial

Praet, S. F., van Rooij, E. S., Wijtvliet, A., Boonman de Winter, L. J., Enneking, T., Kuipers, H., Stehouwer, C. D. & van Loon, L. J., 1 Jan 2008, In : Diabetologia. 51, 5, p. 736-46

Research output: Contribution to journalArticleAcademicpeer-review

61 Citations (Scopus)

Calpain-10 Gene and Protein Expression in Human Skeletal Muscle: Effect of Acute Lipid-Induced Insulin Resistance and Type 2 Diabetes.

Norton, I., Parr, T., Chokkalingam, K., Bardsley, R. G., Ye, H., Bell, G. I., Pelsers, M. M., van Loon, L. J. & Tsintzas, K., 1 Jan 2008, In : Journal of Clinical Endocrinology & Metabolism. 93, 3, p. 992-998

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Coingestion of carbohydrate and protein hydrolysate stimulates muscle protein synthesis during exercise in young men, with no further increase during subsequent overnight recovery

Beelen, M., Tieland, M., Gijsen, A. P., Vandereyt, H., Kies, A. K., Kuipers, H., Saris, W. H., Koopman, R. & van Loon, L. J., 1 Jan 2008, In : Journal of Nutrition. 138, 11, p. 2198-204

Research output: Contribution to journalArticleAcademicpeer-review

49 Citations (Scopus)

Co-ingestion of leucine with protein does not further augment post-exercise muscle protein synthesis rates in elderly men.

Koopman, R., Verdijk, L. B., Beelen, M., Gorselink, M., Nieuwenhuijzen Kruseman, A., Wagenmakers, A. J., Kuipers, H. & van Loon, L. J., 1 Jan 2008, In : British Journal of Nutrition. 99, 3, p. 571-580

Research output: Contribution to journalArticleAcademicpeer-review

65 Citations (Scopus)

Early or advanced stage type 2 diabetes is not accompanied by in vivo skeletal muscle mitochondrial dysfunction

Feyter, H. M., van den Broek, N. M., Praet, S. F., Nicolay, K., van Loon, L. J. & Prompers, J. J., 1 Jan 2008, In : European Journal of Endocrinology. 158, 5, p. 643-53

Research output: Contribution to journalArticleAcademicpeer-review

69 Citations (Scopus)

Exercise: the brittle cornerstone of type 2 diabetes treatment

Praet, S. F. & van Loon, L. J., 1 Jan 2008, In : Diabetologia. 51, 3, p. 398-401

Research output: Contribution to journalArticleAcademicpeer-review

32 Citations (Scopus)

Four weeks' corticosteroid inhalation does not augment maximal power output in endurance athletes.

Kuipers, H., van 't Hullenaar, G. A., Pluim, B. M., Overbeek, S. E., De Hon, O., van Breda, E. & van Loon, L. J., 1 Jan 2008, In : British Journal of Sports Medicine. 42, 11, p. 568-571

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Scopus)

Intravenous AICAR administration reduces hepatic glucose output and inhibits whole body lipolysis in type 2 diabetic patients.

Boon, H., Bosselaar, M., Praet, S. F., Blaak, E. E., Saris, W. H., Wagenmakers, A. J., McGee, S. L., Tack, C. J., Smits, P., Hargreaves, M. & van Loon, L. J., 1 Jan 2008, In : Diabetologia. 51, 10, p. 1893-1900

Research output: Contribution to journalArticleAcademicpeer-review

63 Citations (Scopus)

Long-standing, insulin-treated type 2 diabetes patients with complications respond well to short-term resistance and interval exercise training

Praet, S. F., Jonkers, R. A., Schep, G., Stehouwer, C. D., Kuipers, H., Keizer, H. A. & van Loon, L. J., 1 Jan 2008, In : European Journal of Endocrinology. 158, 2, p. 163-72

Research output: Contribution to journalArticleAcademicpeer-review

41 Citations (Scopus)