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- 2018
- PublishedIglesias, V. S., Theys, J., Groot, A. J., Barbeau, L. M. O., Lemmens, A., Yaromina, A., ... Vooijs, M. (2018). Synergistic Effects of NOTCH/gamma-Secretase Inhibition and Standard of Care Treatment Modalities in Non-small Cell Lung Cancer Cells. Frontiers in Oncology, 8, [460]. DOI: 10.3389/fonc.2018.00460
- Published
- PublishedRekers, N. H., Pimentel, V. O., Yaromina, A., Lieuwes, N. G., Biemans, R., Zegers, C. M. L., ... Lambin, P. (2018). The immunocytokine L19-IL2: An interplay between radiotherapy and long-lasting systemic anti-tumour immune responses. OncoImmunology , 7(4). DOI: 10.1080/2162402X.2017.1414119
- 2017
- PublishedPeerlings, J., Van De Voorde, L., Mitea, C., Larue, R., Yaromina, A., Sandeleanu, S., ... Mottaghy, F. M. (2017). Hypoxia and hypoxia response-associated molecular markers in esophageal cancer: A systematic review. Methods, 130, 51-62. DOI: 10.1016/j.ymeth.2017.07.002
- PublishedTroost, E. G. C., Koi, L., Yaromina, A., & Krause, M. (2017). Therapeutic options to overcome tumor hypoxia in radiation oncology. Clinical and Translational Imaging, 5(5), 455-464. DOI: 10.1007/s40336-017-0247-6
- PublishedYaromina, A., Granzier, M., Biemans, R., Lieuwes, N., van Elmpt, W., Shakirin, G., ... Lambin, P. (2017). A novel concept for tumour targeting with radiation: Inverse dose-painting or targeting the "Low Drug Uptake Volume". Radiotherapy and Oncology, 124(3), 513-520. DOI: 10.1016/j.radonc.2017.04.020
- PublishedDe-Colle, C., Yaromina, A., Hennenlotter, J., Thames, H., Mueller, A-C., Neumann, T., ... Menegakis, A. (2017). Ex vivo gamma H2AX radiation sensitivity assay in prostate cancer: Inter-patient and intra-patient heterogeneity. Radiotherapy and Oncology, 124(3), 386-394. DOI: 10.1016/j.radonc.2017.08.020
- Publishedvan Kuijk, S. J. A., Parvathaneni, N. K., Niemans, R., van Gisbergen, M. W., Carta, F., Vullo, D., ... Lambin, P. (2017). New approach of delivering cytotoxic drugs towards CAIX expressing cells: A concept of dual-target drugs. European Journal of Medicinal Chemistry, 127, 691-702. DOI: 10.1016/j.ejmech.2016.10.037
- PublishedLambin, P., Zindler, J., Vanneste, B. G. L., Van De Voorde, L., Eekers, D., Compter, I., ... Walsh, S. (2017). Decision support systems for personalized and participative radiation oncology. Advanced Drug Delivery Reviews, 109, 131-153. DOI: 10.1016/j.addr.2016.01.006
- Published
- 2016
- PublishedJentsch, C., Bergmann, R., Bruechner, K., Mosch, B., Yaromina, A., Krause, M., ... Beuthien-Baumann, B. (2016). Impact of pre- and early per-treatment FDG-PET based dose-escalation on local tumour control in fractionated irradiated FaDu xenograft tumours. Radiotherapy and Oncology, 121(3), 447-452. DOI: 10.1016/j.radonc.2016.07.024
- PublishedRekers, N. H., Pimentel, V. O., Yaromina, A., Dubois, L., & Lambin, P. (2016). IL2 based immunotherapies: towards a personalized and curative antitumor response. Translational Cancer Research, 5(Suppl 6), S1292-S1294. DOI: 10.21037/tcr.2016.11.26
- Publishedvan Kuijk, S. J. A., Gieling, R. G., Niemans, R., Lieuwes, N. G., Biemans, R., Telfer, B. A., ... Williams, K. J. (2016). The Sulfamate Small Molecule CAIX Inhibitor S4 Modulates Doxorubicin Efficacy. PLOS ONE, 11(8), [e0161040]. DOI: 10.1371/journal.pone.0161040
- PublishedSneddon, D., Niemans, R., Bauwens, M., Yaromina, A., van Kuijk, S. J. A., Lieuwes, N. G., ... Poulsen, S-A. (2016). Synthesis and in Vivo Biological Evaluation of Ga-68-Labeled Carbonic Anhydrase IX Targeting Small Molecules for Positron Emission Tomography. Journal of Medicinal Chemistry, 59(13), 6431-6443. DOI: 10.1021/acs.jmedchem.6b00623
- PublishedWack, L. J., Moennich, D., Yaromina, A., Zips, D., Baumann, M., & Thorwarth, D. (2016). Correlation of FMISO simulations with pimonidazole-stained tumor xenografts: A question of O-2 consumption? Medical Physics, 43(7), 4113-4121. DOI: 10.1118/1.4951728
- Publishedvan Kuijk, S. J. A., Yaromina, A., Houben, R., Niemans, R., Lambin, P., & Dubois, L. J. (2016). Prognostic Significance of Carbonic Anhydrase IX expression in Cancer Patients: A Meta-Analysis. Frontiers in Oncology, 6, [69]. DOI: 10.3389/fonc.2016.00069
- PublishedPanth, K. M., van den Beucken, T., Biemans, R., Lieuwes, N. G., Weber, M., Losen, M., ... Lambin, P. (2016). In vivo optical imaging of MMP2 immuno protein antibody: tumor uptake is associated with MMP2 activity. Scientific Reports, 6, [22198]. DOI: 10.1038/srep22198
- 2015
- PublishedTrani, D., Yaromina, A., Dubois, L., Granzier, M., Peeters, S. G. J. A., Biemans, R., ... Lambin, P. (2015). Preclinical Assessment of Efficacy of Radiation Dose Painting Based on Intratumoral FDG-PET Uptake. Clinical Cancer Research, 21(24), 5511-5518. DOI: 10.1158/1078-0432.CCR-15-0290
- PublishedRekers, N. H., Zegers, C. M. L., Yaromina, A., Lieuwes, N. G., Biemans, R., Senden-Gijsbers, B. L. M. G., ... Lambin, P. (2015). Combination of radiotherapy with the immunocytokine L19-IL2: Additive effect in a NK cell dependent tumour model. Radiotherapy and Oncology, 116(3), 438-442. DOI: 10.1016/j.radonc.2015.06.019
- PublishedMenegakis, A., von Neubeck, C., Yaromina, A., Thames, H., Hering, S., Hennenlotter, J., ... Baumann, M. (2015). gamma H2AX assay in ex vivo irradiated tumour specimens: A novel Method to determine tumour radiation sensitivity in patient-derived material. Radiotherapy and Oncology, 116(3), 473-479. DOI: 10.1016/j.radonc.2015.03.026
- PublishedPanth, K. M., Leijenaar, R. T. H., Carvalho, S., Lieuwes, N. G., Yaromina, A., Dubois, L., & Lambin, P. (2015). Is there a causal relationship between genetic changes and radiomics-based image features? An in vivo preclinical experiment with doxycycline inducible GADD34 tumor cells. Radiotherapy and Oncology, 116(3), 462-466. DOI: 10.1016/j.radonc.2015.06.013
- PublishedDubois, L. J., Niemans, R., van Kuijk, S. J. A., Panth, K. M., Parvathaneni, N-K., Peeters, S. G. J. A., ... Lambin, P. (2015). New ways to image and target tumour hypoxia and its molecular responses. Radiotherapy and Oncology, 116(3), 352-357. DOI: 10.1016/j.radonc.2015.08.022
- PublishedPeeters, S. G. J. A., Zegers, C. M. L., Biemans, R., Lieuwes, N. G., van Stiphout, R. G. P. M., Yaromina, A., ... Lambin, P. (2015). TH-302 in Combination with Radiotherapy Enhances the Therapeutic Outcome and Is Associated with Pretreatment [F-18]HX4 Hypoxia PET Imaging. Clinical Cancer Research, 21(13), 2984-2992. DOI: 10.1158/1078-0432.CCR-15-0018
- PublishedTrani, D., Reniers, B., Persoon, L., Podesta, M., Nalbantov, G., Leijenaar, R. T. H., ... Lambin, P. (2015). What Level of Accuracy Is Achievable for Preclinical Dose Painting Studies on a Clinical Irradiation Platform? Radiation Research, 183(5), 501-510. DOI: 10.1667/RR13933.1
- PublishedPeeters, S. G. J. A., Zegers, C. M. L., Yaromina, A., Van Elmpt, W., Dubois, L., & Lambin, P. (2015). Current preclinical and clinical applications of hypoxia PET imaging using 2-nitroimidazoles. Quarterly Journal of Nuclear Medicine and Molecular Imaging, 59(1), 39-57.
- PublishedZegers, C. M. L., Rekers, N. H., Quaden, D. H. F., Lieuwes, N. G., Yaromina, A., Germeraad, W. T. V., ... Lambin, P. (2015). Radiotherapy Combined with the Immunocytokine L19-IL2 Provides Long-lasting Antitumor Effects. Clinical Cancer Research, 21(5), 1151-1160. DOI: 10.1158/1078-0432.CCR-14-2676
- 2014
- PublishedHelbig, L., Koi, L., Bruechner, K., Gurtner, K., Hess-Stumpp, H., Unterschemmann, K., ... Yaromina, A. (2014). BAY 87-2243, a novel inhibitor of hypoxia-induced gene activation, improves local tumor control after fractionated irradiation in a schedule-dependent manner in head and neck human xenografts. Radiation Oncology, 9, [207]. DOI: 10.1186/1748-717X-9-207
- PublishedSchuetze, C., Bergmann, R., Bruechner, K., Mosch, B., Yaromina, A., Zips, D., ... Beuthien-Baumann, B. (2014). Effect of [F-18]FMISO stratified dose-escalation on local control in FaDu hSCC in nude mice. Radiotherapy and Oncology, 111(1), 81-87. DOI: 10.1016/j.radonc.2014.02.005
- PublishedHelbig, L., Koi, L., Bruechner, K., Gurtner, K., Hess-Stumpp, H., Unterschemmann, K., ... Zips, D. (2014). Hypoxia-Inducible Factor Pathway Inhibition Resolves Tumor Hypoxia and Improves Local Tumor Control After Single-Dose Irradiation. International Journal of Radiation Oncology Biology Physics, 88(1), 159-166. DOI: 10.1016/j.ijrobp.2013.09.047
- 2013
- PublishedDubois, L., Peeters, S. G. J. A., van Kuijk, S. J. A., Yaromina, A., Lieuwes, N. G., Saraya, R., ... Lambin, P. (2013). Targeting carbonic anhydrase IX by nitroimidazole based sulfamides enhances the therapeutic effect of tumor irradiation: A new concept of dual targeting drugs. Radiotherapy and Oncology, 108(3), 523-528. DOI: 10.1016/j.radonc.2013.06.018