New approach of delivering cytotoxic drugs towards CAIX expressing cells: A concept of dual-target drugs

Simon J. A. van Kuijk*, Nanda Kumar Parvathaneni*, Raymon Niemans, Marilee W. van Gisbergen, Fabrizio Carta, Daniela Vullo, Silvia Pastorekova, Ala Yaromina, Claudiu T. Supuran, Ludwig J. Dubois, Jean-Yves Winurn, Philippe Lambin

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

16 Citations (Web of Science)
Original languageEnglish
Pages (from-to)691-702
Number of pages12
JournalEuropean Journal of Medicinal Chemistry
Volume127
DOIs
Publication statusPublished - 15 Feb 2017

Keywords

  • Tumor
  • Hypoxia
  • Carbonic anhydrase IX
  • Dual-target drugs
  • CAIX inhibitors
  • Cytotoxic drugs
  • CARBONIC-ANHYDRASE-IX
  • HYPOXIA-INDUCED EXPRESSION
  • IN-VIVO
  • TUMOR HYPOXIA
  • BIOLOGICAL EVALUATION
  • CANCER-CELLS
  • INHIBITORS
  • THERAPY
  • RADIATION
  • RESPONSES

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