New approach of delivering cytotoxic drugs towards CAIX expressing cells: A concept of dual-target drugs

Simon J. A. van Kuijk, Nanda Kumar Parvathaneni, Raymon Niemans, Marilee W. van Gisbergen, Fabrizio Carta, Daniela Vullo, Silvia Pastorekova, Ala Yaromina, Claudiu T. Supuran, Ludwig J. Dubois, Jean-Yves Winurn, Philippe Lambin

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)691-702
Number of pages12
JournalEuropean Journal of Medicinal Chemistry
Volume127
DOIs
Publication statusPublished - 15 Feb 2017

Keywords

  • Tumor
  • Hypoxia
  • Carbonic anhydrase IX
  • Dual-target drugs
  • CAIX inhibitors
  • Cytotoxic drugs
  • CARBONIC-ANHYDRASE-IX
  • HYPOXIA-INDUCED EXPRESSION
  • IN-VIVO
  • TUMOR HYPOXIA
  • BIOLOGICAL EVALUATION
  • CANCER-CELLS
  • INHIBITORS
  • THERAPY
  • RADIATION
  • RESPONSES

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