Ex vivo gamma H2AX radiation sensitivity assay in prostate cancer: Inter-patient and intra-patient heterogeneity

Chiara De-Colle, Ala Yaromina, Joerg Hennenlotter, Howard Thames, Arndt-Christian Mueller, Tim Neumann, Arnulf Stenzl, Marcus Scharpf, Falko Fend, Umberto Ricardi, Michael Baumann, Daniel Zips, Apostolos Menegakis*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)386-394
Number of pages9
JournalRadiotherapy and Oncology
Volume124
Issue number3
DOIs
Publication statusPublished - Sep 2017
Event15th International Wolfsberg Meeting on Molecular Radiation Biology/Oncology - SWITZERLAND, Switzerland
Duration: 17 Jun 201719 Jun 2017

Keywords

  • Ex vivo
  • gamma H2AX foci
  • Intrinsic radiation sensitivity
  • Prostate cancer
  • Intra-patient variability
  • Inter-patient variability
  • Personalized radiation oncology
  • DOUBLE-STRAND BREAKS
  • TUMOR HETEROGENEITY
  • DNA-DAMAGE
  • CELL-SURVIVAL
  • HISTONE H2AX
  • DEPHOSPHORYLATES GAMMA-H2AX
  • INTRINSIC RADIOSENSITIVITY
  • RADICAL PROSTATECTOMY
  • CERVICAL-CARCINOMA
  • REPAIR

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