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Researcher

van der Kallen, C.J.H.

Assistant Professor

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  1. 2019
  2. E-pub ahead of print
    Vergoossen, L. W., Schram, M. T., de Jong, J. J., Stehouwer, C. D., Schaper, N. C., Henry, R. M., ... Jansen, J. F. (2019). White Matter Connectivity Abnormalities in Prediabetes and Type 2 Diabetes: The Maastricht Study. Diabetes Care. https://doi.org/10.2337/dc19-0762
  3. E-pub ahead of print
    van der Kolk, B. W., Kalafati, M., Adriaens, M., van Greevenbroek, M. M. J., Vogelzangs, N., Saris, W. H. M., ... Blaak, E. E. (2019). Subcutaneous Adipose Tissue and Systemic Inflammation are Associated with Peripheral But Not Hepatic Insulin Resistance in Humans. Diabetes. https://doi.org/10.2337/db19-0560
  4. Published
    BIOS Consortium, CHARGE Consortium Epigenetics Working Group, CHARGE Consortium Nutrition Working Group (2019). Association of dietary folate and vitamin B-12 intake with genome-wide DNA methylation in blood: a large-scale epigenome-wide association analysis in 5841 individuals. American Journal of Clinical Nutrition, 110(2), 437-450. [15]. https://doi.org/10.1093/ajcn/nqz031
  5. Published
    Maasen, K., van Greevenbroek, M. M. J., Scheijen, J. L. J. M., van der Kallen, C. J. H., Stehouwer, C. D. A., & Schalkwijk, C. G. (2019). High dietary glycemic load is associated with higher concentrations of urinary advanced glycation endproducts: the Cohort on Diabetes and Atherosclerosis Maastricht (CODAM) Study. American Journal of Clinical Nutrition, 110(2), 358-366. https://doi.org/10.1093/ajcn/nqz119
  6. Published
    eQTLGen Consortium, BIOS Consortium, Porcu, E., Rueger, S., Lepik, K., Agbessi, M., ... van Greevenbroek, M. M. J. (2019). Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits. Nature Communications, 10, [3300]. https://doi.org/10.1038/s41467-019-10936-0
  7. Published
    O'Donovan, S. D., Lenz, M., Goossens, G. H., van der Kallen, C. J. H., Eussen, S. J. M. P., Stehouwer, C. D. A., ... Arts, I. C. W. (2019). Improved quantification of muscle insulin sensitivity using oral glucose tolerance test data: the MISI Calculator. Scientific Reports, 9, [9388]. https://doi.org/10.1038/s41598-019-45858-w
  8. Published
    BBMRI Metabolomics Consortium, Onderwater, G. L. J., Ligthart, L., Bot, M., Demirkan, A., Fu, J., ... van den Maagdenberg, A. M. J. M. (2019). Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine. Neurology, 92(16), E1899-E1911. https://doi.org/10.1212/WNL.0000000000007313
  9. Published
    den Biggelaar, L. J. C. J., Eussen, S. J. P. M., Sep, S. J. S., Mari, A., Ferrannini, E., van Greevenbroek, M. M., ... Dagnelie, P. C. (2019). Prospective associations of dietary carbohydrate, fat, and protein intake with -cell function in the CODAM study. European Journal of Nutrition, 58(2), 597-608. https://doi.org/10.1007/s00394-018-1644-y
  10. Published
    Driessen, J. H. M., de Vries, F., van Onzenoort, H. A. W., Schram, M. T., van der Kallen, C., Reesink, K. D., ... Henry, R. M. A. (2019). Metformin use in type 2 diabetic patients is not associated with lower arterial stiffness: the Maastricht Study. Journal of Hypertension, 37(2), 365-371. https://doi.org/10.1097/HJH.0000000000001892
  11. 2018
  12. Published
    Sun, C., Ippel, L., Wouters, B., Soest, J. V., Malic, A., Adekunle, O., ... Dumontier, M. (2018). Analyzing Partitioned FAIR Health Data Responsibly. arXiv , 1-6.
  13. Published
    van Agtmaal, M. J. M., Houben, A. J. H. M., de Wit, V., Henry, R. M. A., Schaper, N. C., Dagnelie, P. C., ... Stehouwer, C. D. A. (2018). Prediabetes Is Associated With Structural Brain Abnormalities: The Maastricht Study. Diabetes Care, 41(12), 2535-2543. https://doi.org/10.2337/dc18-1132
  14. Published
    't Hart, L. M., Vogelzangs, N., Mook-Kanamori, D. O., Brahimaj, A., Nano, J., van der Heijden, A. A. W. A., ... van Greevenbroek, M. M. J. (2018). Blood Metabolomic Measures Associate With Present and Future Glycemic Control in Type 2 Diabetes. Journal of Clinical Endocrinology & Metabolism, 103(12), 4569-4579. https://doi.org/10.1210/jc.2018-01165
  15. Published
    Xin, Y., Hertle, E., van der Kallen, C. J. H., Schalkwijk, C. G., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2018). Complement C3 and C4, but not their regulators or activated products, are associated with incident metabolic syndrome: the CODAM study. Endocrine, 62(3), 617-627. https://doi.org/10.1007/s12020-018-1712-3
  16. Published
    de Waard, E. A. C., de Jong, J. J. A., Koster, A., Savelberg, H. H. C. M., van Geel, T. A., Houben, A. J. H. M., ... van den Bergh, J. P. W. (2018). The association between diabetes status, HbA1c, diabetes duration, microvascular disease, and bone quality of the distal radius and tibia as measured with high-resolution peripheral quantitative computed tomography: The Maastricht Study. Osteoporosis International, 29(12), 2725-2738. https://doi.org/10.1007/s00198-018-4678-3
  17. Published
    van der Velde, J. H. P. M., Schaper, N. C., Stehouwer, C. D. A., van der Kallen, C. J. H., Sep, S. J. S., Schram, M. T., ... Koster, A. (2018). Which is more important for cardiometabolic health: sedentary time, higher intensity physical activity or cardiorespiratory fitness? The Maastricht Study. Diabetologia, 61(12), 2561-2569. https://doi.org/10.1007/s00125-018-4719-7
  18. Published
    CODAM study, Maastricht Study, & DiOGenes Consortium (2018). Abdominal subcutaneous adipose tissue gene expression in relation to tissue-specific insulin resistance in human obesity. Diabetologia, 61, S110-S110.
  19. Published
    Geijselaers, S. L. C., Sep, S. J. S., Schram, M. T., van Boxtel, M. P. J., van Sloten, T. T., Roodt, J. O. H., ... Stehouwer, C. D. A. (2018). Carotid circumferential wall stress is not associated with cognitive performance among individuals in late middle age: The Maastricht Study. Atherosclerosis, 276, 15-22. https://doi.org/10.1016/j.atherosclerosis.2018.07.003
  20. Published
    de Waard, E. A. C., Sarodnik, C., Pennings, A., de Jong, J. J. A., Savelberg, H. H. C. M., van Geel, T. A., ... van den Bergh, J. P. W. (2018). Reliability of HR-pQCT Derived Cortical Bone Structural Parameters When Using Uncorrected Instead of Corrected Automatically Generated Endocortical Contours in a Cross-Sectional Study: The Maastricht Study. Calcified Tissue International, 103(3), 252-265. https://doi.org/10.1007/s00223-018-0416-2
  21. Published
    Brinkhues, S., Dukers-Muijrers, N. H. T. M., Hoebe, C. J. P. A., van der Kallen, C. J. H., Koster, A., Henry, R. M. A., ... Schram, M. T. (2018). Social Network Characteristics Are Associated With Type 2 Diabetes Complications: The Maastricht Study. Diabetes Care, 41(8), 1654-1662. https://doi.org/10.2337/dc17-2144
  22. Published
    Veugen, M. G. J., Henry, R. M. A., Brunner-La Rocca, H-P., Dagnelie, P. C., Schram, M. T., van Agtmaal, M. J. M., ... Stehouwer, C. D. A. (2018). Cross-sectional associations between cardiac biomarkers, cognitive performance, and structural brain changes are modified by age: The Maastricht Study. Arteriosclerosis Thrombosis and Vascular Biology, 38(8), 1948-1958. https://doi.org/10.1161/ATVBAHA.118.311082
  23. Published
    Scheijen, J. L. J. M., Hanssen, N. M. J., van Greevenbroek, M. M., van der Kallen, C. J., Feskens, E. J. M., Stehouwer, C. D. A., & Schalkwijk, C. G. (2018). Dietary intake of advanced glycation endproducts is associated with higher levels of advanced glycation endproducts in plasma and urine: The CODAM study. Clinical Nutrition, 37(3), 919-925. https://doi.org/10.1016/j.clnu.2017.03.019
  24. Published
    Hertle, E., Arts, I. C. W., van der Kallen, C. J. H., Feskens, E. J. M., Schalkwijk, C. G., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2018). Classical Pathway of Complement Activation: Longitudinal Associations of C1q and C1-INH With Cardiovascular Outcomes: The CODAM Study (Cohort on Diabetes and Atherosclerosis Maastricht)Brief Report. Arteriosclerosis Thrombosis and Vascular Biology, 38(5), 1242-1244. https://doi.org/10.1161/ATVBAHA.118.310806
  25. Published
    Xin, Y., Hertle, E., van der Kallen, C. J. H., Schalkwijk, C. G., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2018). Longitudinal associations of the alternative and terminal pathways of complement activation with adiposity: The CODAM study. Obesity Research & Clinical Practice, 12(3), 286-292. https://doi.org/10.1016/j.orcp.2017.11.002
  26. Published
    Martens, R. J. H., Houben, A. J. H. M., Kooman, J. P., Berendschot, T. T. J. M., Dagnelie, P. C., van der Kallen, C. J. H., ... Stehouwer, C. D. A. (2018). Microvascular endothelial dysfunction is associated with albuminuria: the Maastricht Study. Journal of Hypertension, 36(5), 1178-1187. https://doi.org/10.1097/HJH.0000000000001674
  27. Published
    Martens, R. J. H., van der Berg, J. D., Stehouwer, C. D. A., Henry, R. M. A., Bosma, H., Dagnelie, P. C., ... Koster, A. (2018). Amount and pattern of physical activity and sedentary behavior are associated with kidney function and kidney damage: The Maastricht Study. PLOS ONE, 13(4), [0195306]. https://doi.org/10.1371/journal.pone.0195306
  28. Published
    Pulakka, A., Stenholm, S., Bosma, H., Schaper, N. C., Savelberg, H. H. C. M., Stehouwer, C. D. A., ... Koster, A. (2018). Association Between Employment Status and Objectively Measured Physical Activity and Sedentary BehaviorThe Maastricht Study. Journal of Occupational and Environmental Medicine, 60(4), 309-315. https://doi.org/10.1097/JOM.0000000000001254
  29. Published
    Onete, V., Henry, R. M., Sep, S. J. S., Koster, A., van der Kallen, C. J., Dagnelie, P. C., ... Schram, M. T. (2018). Arterial stiffness is associated with depression in middle-aged men - the Maastricht Study. Journal of Psychiatry & Neuroscience, 43(2), 111-119. https://doi.org/10.1503/jpn.160246
  30. Published
    Zhou, T. L., Reesink, K., Schram, M., Koster, A., Schaper, N., Dagnelie, P., ... Henry, R. (2018). Blood pressure variability in individuals with and without (pre)diabetes: the Maastricht Study. Journal of Hypertension, 36(2), 259-267. https://doi.org/10.1097/HJH.0000000000001543
  31. Published
    Yousefi, S., Abbassi-Daloii, T., Kraaijenbrink, T., Vermaat, M., Mei, H., van't Hof, P., ... Franke, L. (2018). A SNP panel for identification of DNA and RNA specimens. BMC Genomics, 19(90), [90]. https://doi.org/10.1186/s12864-018-4482-7
  32. Published
    Martens, R. J. H., Kooman, J. P., Stehouwer, C. D. A., Dagnelie, P. C., van der Kallen, C. J. H., Kroon, A. A., ... Henry, R. M. A. (2018). Albuminuria is associated with a higher prevalence of depression in a population-based cohort study: the Maastricht Study. Nephrology Dialysis Transplantation, 33(1), 128-138. https://doi.org/10.1093/ndt/gfw377
  33. Published
    Wanders, A. J., Alssema, M., De Hoon, S. E. M., Feskens, E. J. M., van Woudenbergh, G. J., van der Kallen, C. J., ... van Greevenbroek, M. M. J. (2018). Circulating Polyunsaturated Fatty Acids as Biomarkers for Dietary Intake across Subgroups: The CODAM and Hoorn Studies. Annals of Nutrition and Metabolism, 72(2), 117-125. https://doi.org/10.1159/000486244
  34. 2017
  35. Published
    Brinkhues, S., Dukers-Muijrers, N. H. T. M., Hoebe, C. J. P. A., van der Kallen, C. J. H., Dagnelie, P. C., Koster, A., ... Schram, M. T. (2017). Socially isolated individuals are more prone to have newly diagnosed and prevalent type 2 diabetes mellitus - the Maastricht study -. BMC Public Health, 17, [955]. https://doi.org/10.1186/s12889-017-4948-6
  36. Published
    Richard, M. A., Huan, T., Ligthart, S., Gondalia, R., Jhun, M. A., Brody, J. A., ... Schalkwijk, C. (2017). DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation. American Journal of Human Genetics, 101(6), 888-902. https://doi.org/10.1016/j.ajhg.2017.09.028
  37. Published
    Geijselaers, S. L. C., Sep, S. J. S., Claessens, D., Schram, M. T., van Boxtel, M. P. J., Henry, R. M. A., ... Stehouwer, C. D. A. (2017). The role of hyperglycemia, insulin resistance, and blood pressure in diabetes: Associated differences in cognitive performance-The Maastricht Study. Diabetes Care, 40(11), 1537-1547. https://doi.org/10.2337/dc17-0330
  38. Published
    Sörensen, B. M., Houben, A. J. H. M., Berendschot, T. T. J. M., Schouten, J. S. A. G., Kroon, A. A., van der Kallen, C. J. H., ... Stehouwer, C. D. A. (2017). Cardiovascular risk factors as determinants of retinal and skin microvascular function: The Maastricht Study. PLOS ONE, 12(10), [e0187324]. https://doi.org/10.1371/journal.pone.0187324
  39. Published
    Scheepers, L. E. J. M., Boonen, A., Dagnelie, P. C., Schram, M. T., van der Kallen, C. J. H., Henry, R. M. A., ... Arts, I. C. W. (2017). Uric acid and blood pressure: exploring the role of uric acid production in The Maastricht Study. Journal of Hypertension, 35(10), 1968-1975. https://doi.org/10.1097/HJH.0000000000001417
  40. Published
    Sörensen, B. M., Houben, A. J. H. M., Berendschot, T. T. J. M., Schouten, J. S. A. G., Kroon, A. A., van der Kallen, C. J. H., ... Stehouwer, C. D. A. (2017). Hyperglycemia Is the Main Mediator of Prediabetes- and Type 2 Diabetes-Associated Impairment of Microvascular Function: The Maastricht Study. Diabetes Care, 40(8), e103-e105. https://doi.org/10.2337/dc17-0574
  41. Published
    Van der Velde, J. H. P. M., Koster, A., Van der Berg, J. D., Sep, S. J. S., Van der Kallen, C. J. H., Dagnelie, P. C., ... Savelberg, H. H. C. M. (2017). Sedentary Behavior, Physical Activity, and Fitness-The Maastricht Study. Medicine and Science in Sports and Exercise, 49(8), 1583-1591. https://doi.org/10.1249/MSS.0000000000001262
  42. Published
    de Waard, E. A. C., Driessen, J. H. M., de Jong, J. J. A., van Geel, T. A. C. M., Henry, R. M. A., van Onzenoort, H. A. W., ... van den Bergh, J. P. W. (2017). The association between insulin use and volumetric bone mineral density, bone micro-architecture and bone strength of the distal radius in patients with type 2 diabetes - The Maastricht study. Bone, 101, 156-161. https://doi.org/10.1016/j.bone.2017.05.004
  43. Published
    Elissen, A. M. J., Hertroijs, D. F. L., Schaper, N. C., Bosma, H., Dagnelie, P. C., Henry, R. M., ... Ruwaard, D. (2017). Differences in biopsychosocial profiles of diabetes patients by level of glycaemic control and health-related quality of life: The Maastricht Study. PLOS ONE, 12(7), [e0182053]. https://doi.org/10.1371/journal.pone.0182053
  44. Published
    Kimenai, D. M., Martens, R. J. H., Kooman, J. P., Stehouwer, C. D. A., Tan, F. E. S., Schaper, N. C., ... Meex, S. J. R. (2017). Troponin I and T in relation to cardiac injury detected with electrocardiography in a population-based cohort - The Maastricht Study. Scientific Reports, 7, [6610]. https://doi.org/10.1038/s41598-017-06978-3
  45. Published
    Van Der Berg, J. D., Van Der Velde, J. P. M., De Waard, E. A. C., Bosma, H., Savelberg, H. H. C. M., Schaper, N. C., ... Koster, A. (2017). Replacement Effects of Sedentary Time on Metabolic Outcomes: The Maastricht Study. Medicine and Science in Sports and Exercise, 49(7), 1351-1358. https://doi.org/10.1249/MSS.0000000000001248
  46. Published
    van der Velde, J. H. P. M., Savelberg, H. H. C. M., van der Berg, J. D., Sep, S. J. S., van der Kallen, C. J. H., Dagnelie, P. C., ... Schaper, N. C. (2017). Sedentary Behavior Is Only Marginally Associated with Physical Function in Adults Aged 40-75 Years - the Maastricht Study. Frontiers in physiology, 8, [242]. https://doi.org/10.3389/fphys.2017.00242
  47. Published
    den Biggelaar, L. J. C. J., Eussen, S. J. P. M., Sep, S. J. S., Mari, A., Ferrannini, E., van Dongen, M. C. J. M., ... Dagnelie, P. C. (2017). Associations of Dietary Glucose, Fructose, and Sucrose with beta-Cell Function, Insulin Sensitivity, and Type 2 Diabetes in the Maastricht Study. Nutrients, 9(4), [380]. https://doi.org/10.3390/nu9040380
  48. Published
    Martens, R. J. H., Kimenai, D. M., Kooman, J. P., Stehouwer, C. D. A., Tan, F. E. S., Bekers, O., ... Henry, R. M. A. (2017). Estimated Glomerular Filtration Rate and Albuminuria Are Associated with Biomarkers of Cardiac Injury in a Population-Based Cohort Study: The Maastricht Study. Clinical Chemistry, 63(4), 887-897. https://doi.org/10.1373/clinchem.2016.266031
  49. Published
    van Moorsel, D., Henry, R. M., Schaper, N. C., van Greevenbroek, M. M., van Rossum, E. F., 't Hart, L. M., ... Havekes, B. (2017). BclI Glucocorticoid Receptor Polymorphism in Relation to Arterial Stiffening and Cardiac Structure and Function: The Hoorn and CODAM Studies. American Journal of Hypertension, 30(3), 286-294. https://doi.org/10.1093/ajh/hpw196
  50. Published
    den Biggelaar, L. J. C. J., Sep, S. J. S., Eussen, S. J. P. M., Mari, A., Ferrannini, E., van Greevenbroek, M. M. J., ... Dagnelie, P. C. (2017). Discriminatory ability of simple OGTT-based beta cell function indices for prediction of prediabetes and type 2 diabetes: the CODAM study. Diabetologia, 60(3), 432-441. https://doi.org/10.1007/s00125-016-4165-3
  51. Published
    Martens, R. J. H., Kooman, J. P., Stehouwer, C. D. A., Dagnelie, P. C., van der Kallen, C. J. H., Koster, A., ... Henry, R. M. A. (2017). Estimated GFR, Albuminuria, and Cognitive Performance: The Maastricht Study. American Journal of Kidney Diseases, 69(2), 179-191. https://doi.org/10.1053/j.ajkd.2016.04.017
  52. Published
    van Dooren, F. E. P., Pouwer, F., Schalkwijk, C. G., Sep, S. J. S., Stehouwer, C. D. A., Henry, R. M. A., ... Schram, M. T. (2017). Advanced Glycation End Product (AGE) Accumulation in the Skin is Associated with Depression: The Maastricht Study. Depression and Anxiety, 34(1), 59-67. https://doi.org/10.1002/da.22527
  53. Published
    Bonder, M. J., Luijk, R., Zhernakova, D. V., Moed, M., Deelen, P., Vermaat, M., ... BIOS Consortium (2017). Disease variants alter transcription factor levels and methylation of their binding sites. Nature Genetics, 49(1), 131-138. https://doi.org/10.1038/ng.3721
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