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Research Output 2008 2018

2018

Influence of Vitamin C on Lymphocytes: An Overview

van Gorkom, G. N. Y., Wolterink, R. G. J. K., Van Elssen, C. H. M. J., Wieten, L., Germeraad, W. T. V. & Bos, G. M. J., 10 Mar 2018, In : Antioxidants. 7, 3, 14 p., 41.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Pathogen recognition by NK cells amplifies the pro-inflammatory cytokine production of monocyte-derived DC via IFN-γ

Oth, T., Habets, T. H. P. M., Germeraad, W. T. V., Zonneveld, M. I., Bos, G. M. J. & Vanderlocht, J., 13 Feb 2018, In : BMC IMMUNOLOGY. 19, 13 p., 8.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The immunocytokine L19-IL2: An interplay between radiotherapy and long-lasting systemic anti-tumour immune responses

Rekers, N. H., Pimentel, V. O., Yaromina, A., Lieuwes, N. G., Biemans, R., Zegers, C. M. L., Germeraad, W. T. V., Van Limbergen, E. J., Neri, D., Dubois, L. J. & Lambin, P., 1 Jan 2018, In : OncoImmunology . 7, 4, 15 p., e1414119.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2016
2 Citations (Scopus)

Ascorbic acid serum levels are reduced in patients with hematological malignancies

Huijskens, M., Wodzig, W., Walczak, M., Germeraad, W. & Bos, G., 2016, In : Results in Immunology. 6, p. 8-10

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Fractionated Radiotherapy with 3 x 8 Gy Induces Systemic Anti-Tumour Responses and Abscopal Tumour Inhibition without Modulating the Humoral Anti-Tumour Response

Habets, T. H. P. M., Oth, T., Houben, A., Huijskens, M. J. A. J., Senden-Gijsbers, B. L. M. G., Schnijderberg, M. C. A., Brans, B., Dubois, L. J., Lambin, P., De Saint-Hubert, M., Germeraad, W. T. V., Tilanus, M. G. J., Mottaghy, F. M., Bos, G. & Vanderlocht, J., 18 Jul 2016, In : PLOS ONE. 11, 7, e0159515.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
1 Citation (Scopus)
2015
5 Citations (Scopus)

An acute intake of plant stanol esters alters immune-related pathways in the jejunum of healthy volunteers

De Smet, E., Mensink, R. P., Boekschoten, M. V., de Ridder, R., Germeraad, W. T. V., Wolfs, T. G. A. M. & Plat, J., 14 Mar 2015, In : British Journal of Nutrition. 113, 5, p. 794-802

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Ascorbic acid promotes proliferation of natural killer cell populations in culture systems applicable for natural killer cell therapy

Huijskens, M. J. A. J., Walczak, M., Sarkar, S., Atrafi, F., Senden-Gijsbers, B. L. M. G., Tilanus, M. G. J., Bos, G. M. J., Wieten, L. & Germeraad, W. T. V., May 2015, In : Cytotherapy. 17, 5, p. 613-620

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)

Combination of radiotherapy with the immunocytokine L19-IL2: Additive effect in a NK cell dependent tumour model

Rekers, N. H., Zegers, C. M. L., Yaromina, A., Lieuwes, N. G., Biemans, R., Senden-Gijsbers, B. L. M. G., Losen, M., Van Limbergen, E. J., Germeraad, W. T. V., Neri, D., Dubois, L. & Lambin, P., Sep 2015, In : Radiotherapy and Oncology. 116, 3, p. 438-442

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Heat-Transfer-Method-Based Cell Culture Quality Assay through Cell Detection by Surface Imprinted Polymers

Eersels, K., van Grinsven, B., Khorshid, M., Somers, V., Puttmann, C., Stein, C., Barth, S., Dilien, H., Bos, G. M. J., Germeraad, W. T. V., Cleij, T. J., Thoelen, R., De Ceuninck, W. & Wagner, P., 17 Feb 2015, In : Langmuir. 31, 6, p. 2043-2050

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Improving the sensitivity of the heat-transfer method (HTM) for cancer cell detection with optimized sensor chips

Eersels, K., van Grinsven, B., Vandenryt, T., Jimenez-Monroy, K. L., Peeters, M., Somers, V., Puettmann, C., Stein, C., Barth, S., Bos, G. M. J., Germeraad, W. T. V., Dilien, H., Cleij, T. J., Thoelen, R., De Ceuninck, W. & Wagner, P., Jun 2015, In : Physica Status Solidi A-applications and Materials Science. 212, 6, p. 1320-1326

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Induced Developmental Arrest of Early Hematopoietic Progenitors Leads to the Generation of Leukocyte Stem Cells

Ikawa, T., Masuda, K., Huijskens, M. J. A. J., Satoh, R., Kakugawa, K., Agata, Y., Miyai, T., Germeraad, W. T. V., Katsura, Y. & Kawamoto, H., 10 Nov 2015, In : Stem Cell Reports. 5, 5, p. 716-727

Research output: Contribution to journalArticleAcademicpeer-review

Long-lasting antitumor effects provided by radiotherapy combined with the immunocytokine L19-IL2

Rekers, N. H., Zegers, C. M. L., Germeraad, W. T., Dubois, L. & Lambin, P., Aug 2015, In : OncoImmunology . 4, 8, p. e1021541

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Multipotent adult progenitor cells for hypoxic-ischemic injury in the preterm brain

Jellema, R. K., Ophelders, D. R. M. G., Zwanenburg, A., Nikiforou, M., Delhaas, T., Andriessen, P., Mays, R. W., Deans, R., Germeraad, W. T. V., Wolfs, T. G. A. M. & Kramer, B. W., 23 Dec 2015, In : Journal of Neuroinflammation. 12, p. 241

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

Optimal selection of natural killer cells to kill myeloma: the role of HLA-E and NKG2A

Sarkar, S., van Gelder, M., Noort, W., Xu, Y., Rouschop, K. M. A., Groen, R., Schouten, H. C., Tilanus, M. G. J., Germeraad, W. T. V., Martens, A. C. M., Bos, G. M. J. & Wieten, L., Aug 2015, In : Cancer Immunology Immunotherapy. 64, 8, p. 951-963

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Potency of Both Human Th1 and NK Helper Cell Activation is Determined by IL-12p70-Producing PAMP-Matured DCs

Oth, T., Van Elssen, C. H. M. J., Schnijderberg, M. C. A., Senden-Gijsbers, B. L. M. G., Germeraad, W. T. V., Bos, G. M. J. & Vanderlocht, J., 1 Sep 2015, In : Journal of Interferon and Cytokine Research. 35, 9, p. 748-758

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

Prophylactic Interleukin-2 Treatment Prevents Fetal Gut Inflammation and Injury in an Ovine Model of Chorioamnionitis

Nikiforou, M., Vanderlocht, J., Chougnet, C. A., Jellema, R. K., Ophelders, D. R. M. G., Joosten, M., Kloosterboer, N., Senden-Gijsbers, B. L. M. G., Germeraad, W. T. V., Kramer, B. W. & Wolfs, T. G. A. M., Sep 2015, In : Inflammatory Bowel Diseases. 21, 9, p. 2026-2038

Research output: Contribution to journalArticleAcademicpeer-review

21 Citations (Scopus)

Radiotherapy Combined with the Immunocytokine L19-IL2 Provides Long-lasting Antitumor Effects

Zegers, C. M. L., Rekers, N. H., Quaden, D. H. F., Lieuwes, N. G., Yaromina, A., Germeraad, W. T. V., Wieten, L., Biessen, E. A. L., Boon, L., Neri, D., Troost, E. G. C., Dubois, L. J. & Lambin, P., Mar 2015, In : Clinical Cancer Research. 21, 5, p. 1151-1160

Research output: Contribution to journalArticleAcademicpeer-review

2014

Five decades of Dutch immunology

Germeraad, W. T. V., de Jong, E. C. & Trouw, L. A., Dec 2014, In : Immunology Letters. 162, 2, p. 83-84

Research output: Contribution to journalArticleAcademicpeer-review

11 Citations (Scopus)

Heat-Transfer Resistance Measurement Method (HTM)-Based Cell Detection at Trace Levels Using a Progressive Enrichment Approach with Highly Selective Cell-Binding Surface Imprints

Bers, K., Eersels, K., van Grinsven, B., Daemen, M., Bogie, J. F. J., Hendriks, J. J. A., Bouwmans, E. E., Puettmann, C., Stein, C., Barth, S., Bos, G. M. J., Germeraad, W. T. V., De Ceuninck, W. & Wagner, P., 1 Apr 2014, In : Langmuir. 30, 12, p. 3631-3639

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Monitoring the Initiation and Kinetics of Human Dendritic Cell-Induced Polarization of Autologous Naive CD4(+) T Cells

Oth, T., Schnijderberg, M. C. A., Senden-Gijsbers, B. L. M. G., Germeraad, W. T. V., Bos, G. M. J. & Vanderlocht, J., 21 Aug 2014, In : PLOS ONE. 9, 8

Research output: Contribution to journalArticleAcademicpeer-review

17 Citations (Scopus)

Natural Killer Cells: The Secret Weapon in Dendritic Cell Vaccination Strategies

Van Elssen, C. H. M. J., Oth, T., Germeraad, W. T. V., Bos, G. M. J. & Vanderlocht, J., 1 Mar 2014, In : Clinical Cancer Research. 20, 5, p. 1095-1103

Research output: Contribution to journalArticleAcademicpeer-review

Stereotactic ablative body radiotherapy combined with immunotherapy: Present status and future perspectives

Rekers, N. H., Troost, E. G. C., Zegers, C. M. L., Germeraad, W. T. V., Dubois, L. J. & Lambin, P., Oct 2014, In : Cancer Radiotherapie. 18, 5-6, p. 391-395

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Technical Advance: Ascorbic acid induces development of double-positive T cells from human hematopoietic stem cells in the absence of stromal cells

Huijskens, M. J. A. J., Walczak, M., Koller, N., Briede, J. J., Senden-Gijsbers, B. L. M. G., Schnijderberg, M. C., Bos, G. M. J. & Germeraad, W. T. V., Dec 2014, In : Journal of Leukocyte Biology. 96, 6, p. 1165-1175

Research output: Contribution to journalArticleAcademicpeer-review

2013
28 Citations (Scopus)

Cerebral inflammation and mobilization of the peripheral immune system following global hypoxia-ischemia in preterm sheep

Jellema, R. K., Passos, V. L., Zwanenburg, A., Ophelders, D. R. M. G., De Munter, S., Vanderlocht, J., Germeraad, W. T. V., Kuypers, E., Collins, J. J. P., Cleutjens, J. P. M., Jennekens, W., Gavilanes, A. W. D., Seehase, M., Vles, H. J., Steinbusch, H., Andriessen, P., Wolfs, T. G. A. M. & Kramer, B. W., 24 Jan 2013, In : Journal of Neuroinflammation. 10, 13.

Research output: Contribution to journalArticleAcademicpeer-review

23 Citations (Scopus)

Hypoxia Induced Impairment of NK Cell Cytotoxicity against Multiple Myeloma Can Be Overcome by IL-2 Activation of the NK Cells

Sarkar, S., Germeraad, W. T. V., Rouschop, K. M. A., Steeghs, E. M. P., van Gelder, M., Bos, G. M. J. & Wieten, L., 28 May 2013, In : PLOS ONE. 8, 5, e64835.

Research output: Contribution to journalArticleAcademicpeer-review

22 Citations (Scopus)

Mesenchymal Stem Cells Induce T-Cell Tolerance and Protect the Preterm Brain after Global Hypoxia-Ischemia

Jellema, R. K., Wolfs, T. G. A. M., Passos, V. L., Zwanenburg, A., Ophelders, D. R. M. G., Kuypers, E., Hopman, A. H. N., Dudink, J., Steinbusch, H. W., Andriessen, P., Germeraad, W. T. V., Vanderlocht, J. & Kramer, B. W., 26 Aug 2013, In : PLOS ONE. 8, 8, e73031.

Research output: Contribution to journalArticleAcademicpeer-review

10 Citations (Scopus)

Systemic G-CSF attenuates cerebral inflammation and hypomyelination but does not reduce seizure burden in preterm sheep exposed to global hypoxia-ischemia

Jellema, R. K., Passos, V. L., Ophelders, D. R. M. G., Wolfs, T. G. A. M., Zwanenburg, A., De Munter, S., Nikiforou, M., Collins, J. J. P., Kuypers, E., Bos, G. M. J., Steinbusch, H. W., Vanderlocht, J., Andriessen, P., Germeraad, W. T. V. & Kramer, B. W., Dec 2013, In : Experimental Neurology. 250, p. 293-303

Research output: Contribution to journalArticleAcademicpeer-review

2012
16 Citations (Scopus)

Ovine Fetal Thymus Response to Lipopolysaccharide-Induced Chorioamnionitis and Antenatal Corticosteroids

Kuypers, E., Collins, J. J. P., Jellema, R. K., Wolfs, T. G. A. M., Kemp, M. W., Nitsos, I., Pillow, J. J., Polglase, G. R., Newnham, J. P., Germeraad, W. T. V., Kallapur, S. G., Jobe, A. H. & Kramer, B. W., 31 May 2012, In : PLOS ONE. 7, 5, e38257.

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

Phage display generation of a novel human anti-CD1A monoclonal antibody with potent cytolytic activity

Bechan, G. I., Lee, D. W., Zajonc, D. M., Heckel, D., Xian, R., Throsby, M., van Meijer, M., Germeraad, W. T. V., Kruisbeek, A. M., Egeler, R. M. & Arceci, R. J., Nov 2012, In : British Journal of Haematology. 159, 3, p. 299-310

Research output: Contribution to journalArticleAcademicpeer-review

2011
4 Citations (Scopus)

Flow cytometry-based assay to evaluate human serum MUC1-Tn antibodies

Van Elssen, C., Clausen, H., Germeraad, W. T. V., Bennet, E. P., Menheere, P. P. C. A., Bos, G. M. J. & Vanderlocht, J., 28 Feb 2011, In : Journal of Immunological Methods. 365, 1-2, p. 87-94 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Inflammation restraining effects of prostaglandin E2 on natural killer-dendritic cell (NK-DC) interaction are imprinted during DC maturation

Van Elssen, C. H. M. J., Vanderlocht, J., Oth, T., Senden-Gijsbers, B. L. M. G., Germeraad, W. T. V. & Bos, G. M. J., 1 Sep 2011, In : Blood. 118, 9, p. 2473-2482

Research output: Contribution to journalArticleAcademicpeer-review

T cells fail to develop in the human skin-cell explants system; an inconvenient truth

Meek, B., Van Elssen, C. H. M. J., Huijskens, M. J. A. J., van der Stegen, S. J. C., Tonnaer, S., Lumeij, S. B. J., Vanderlocht, J., Kirkland, M. A., Hesselink, R., Germeraad, W. T. V. & Bos, G. M. J., 18 Feb 2011, In : BMC IMMUNOLOGY. 12, p. 13

Research output: Contribution to journalArticleAcademicpeer-review

2010

Expression of aberrantly glycosylated Mucin-1 in ovarian cancer

Van Elssen, C. H. M. J., Frings, P. W. H., Bot, F. J., Van de Vijver, K. K., Huls, M. B., Meek, B., Hupperets, P., Germeraad, W. T. V. & Bos, G. M. J., Oct 2010, In : Histopathology. 57, 4, p. 597-606

Research output: Contribution to journalArticleAcademicpeer-review

In vitro-differentiated T/natural killer-cell progenitors derived from human CD34(+) cells mature in the thymus

Meek, B., Cloosen, S., Borsotti, C., Van Elssen, C. H. M. J., Vanderlocht, J., Schnijderberg, M. C. A., van der Poel, M. W. M., Leewis, B., Hesselink, R., Manz, M. G., Katsura, Y., Kawamoto, H., Germeraad, W. T. V. & Bos, G. M. J., 14 Jan 2010, In : Blood. 115, 2, p. 261-264

Research output: Contribution to journalArticleAcademicpeer-review

Klebsiella pneumoniae-triggered DC recruit human NK cells in a CCR5-dependent manner leading to increased CCL19-responsiveness and activation of NK cells

Van Elssen, C. H. M. J., Vanderlocht, J., Frings, P. W. H., Senden-Gijsbers, B. L. M. G., Schnijderberg, M. C. A., van Gelder, M., Meek, B., Libon, C., Ferlazzo, G., Germeraad, W. T. V. & Bos, G. M. J., Nov 2010, In : European Journal of Immunology. 40, 11, p. 3138-3149

Research output: Contribution to journalArticleAcademicpeer-review

Thymic cysts originate from Foxn1 positive thymic medullary epithelium

Vroegindeweij, E., Crobach, S., Itoi, M., Satoh, R., Zuklys, S., Happe, C., Germeraad, W. T. V., Cornelissen, J. J., Cupedo, T., Hollander, G. A., Kawamoto, H. & van Ewijk, W., Feb 2010, In : Molecular Immunology. 47, 5, p. 1106-1113

Research output: Contribution to journalArticleAcademicpeer-review

2008
18 Citations (Scopus)

Increased release of sMD-2 during human endotoxemia and sepsis: a role for endothelial cells.

Wolfs, T. G., Dunn-Siegrist, I., van 't Veer, C., Hodin, C. M., Germeraad, W. T. V., van Zoelen, M., van Suylen, R. J., Peutz-Kootstra, C. J., Elson, G., Pugin, J. & Buurman, W. A., 1 Jan 2008, In : Molecular Immunology. 45, 11, p. 3268-3277

Research output: Contribution to journalArticleAcademicpeer-review