Long-lasting antitumor effects provided by radiotherapy combined with the immunocytokine L19-IL2

Nicolle H Rekers*, Catharina M L Zegers, Wilfred Tv Germeraad, Ludwig Dubois, Philippe Lambin

*Corresponding author for this work

Research output: Contribution to journalEditorialAcademicpeer-review


Recently, we have shown that radiotherapy (RT) combined with L19-IL2 can induce a long-lasting antitumor effect, dependent on ED-B expression and infiltration of cytotoxic T cells. These findings will be translated to a Phase I clinical study (NCT02086721) in patients with oligometastatic solid tumors. See this link for the animation: http://youtu.be/xHbwQuCTkRc.

Original languageEnglish
Article numbere1021541
Issue number8
Publication statusPublished - Aug 2015

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