Ascorbic acid serum levels are reduced in patients with hematological malignancies

Mirelle Huijskens, Will Wodzig, Mateusz Walczak, Wilfred Germeraad*, Gerardus Bos

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


In this paper we demonstrate that patients treated with chemotherapy and/or hematopoietic stem cell transplantation (HSCT) have highly significant reduced serum ascorbic acid (AA) levels compared to healthy controls. We recently observed in in vitro experiments that growth of both T and NK cells from hematopoietic stem cells is positively influenced by AA. It might be of clinical relevance to study the function and recovery of immune cells after intensive treatment, its correlation to AA serum levels and the possible effect of AA supplementation.
Original languageEnglish
Pages (from-to)8-10
JournalResults in Immunology
Publication statusPublished - 2016

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