20082020

Research output per year

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Research Output

2020

Development of a Plasma-Based Assay to Measure the Susceptibility of Factor V to Inhibition by the C-Terminus of TFPI alpha

van Doorn, P., Rosing, J., Campello, E., Middeldorp, S., Simioni, P., Meijers, J. C. M., Hackeng, T. M. & Castoldi, E., Jan 2020, In : Thrombosis and Haemostasis. 120, 1, p. 55-64 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Platelet protein S limits venous but not arterial thrombosis propensity by controlling coagulation in the thrombus

Calzavarini, S., Prince-Eladnani, R., Saller, F., Bologna, L., Burnier, L., Brisset, A. C., Quarroz, C., Caro, M. D. R., Ermolayev, V., Matsumura, Y., Fernandez, J. A., Hackeng, T. M., Griffin, J. H. & Angelillo-Scherrer, A., 28 May 2020, In : Blood. 135, 22, p. 1969-1982 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

2019

Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death

Silvestre-Roig, C., Braster, Q., Wichapong, K., Lee, E. Y., Marie Teulon, J., Berrebeh, N., Winter, J., Adrover, J. M., Santos, G. S., Froese, A., Lemnitzer, P., Ortega-Gomez, A., Chevre, R., Marschner, J., Schumski, A., Winter, C., Perez-Olivares, L., Pan, C., Paulin, N., Schoufour, T. & 19 others, Hartwig, H., Gonzalez-Ramos, S., Kamp, F., Megens, R. T. A., Mowen, K. A., Gunzer, M., Maegdefessel, L., Hackeng, T., Lutgens, E., Daemen, M., von Blume, J., Anders, H-J., Nikolaev, V. O., Pellequer, J-L., Weber, C., Hidalgo, A., Nicolaes, G. A. F., Wong, G. C. L. & Soehnlein, O., 9 May 2019, In : Nature. 569, 7755, p. 236-240 25 p.

Research output: Contribution to journalArticleAcademicpeer-review

SecScan: a general approach for mapping disulfide bonds in synthetic and recombinant peptides and proteins

Denisov, S. S., Ippel, J. H., Mans, B. J., Dijkgraaf, I. & Hackeng, T. M., 4 Feb 2019, In : Chemical Communications. 55, 10, p. 1374-1377 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Synthesis of Constrained Tetracyclic Peptides by Consecutive CEPS, CLIPS, and Oxime Ligation

Streefkerk, D. E., Schmidt, M., Ippel, J. H., Hackeng, T. M., Nuijens, T., Timmerman, P. & van Maarseveen, J. H., 5 Apr 2019, In : Organic Letters. 21, 7, p. 2095-2100 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Tick saliva protein Evasin-3 modulates chemotaxis by disrupting CXCL8 interactions with glycosaminoglycans and CXCR2

Denisov, S. S., Ippel, J. H., Heinzmann, A. C. A., Koenen, R. R., Ortega-Gomez, M., Soehnlein, O., Hackeng, T. M. & Dijkgraaf, I., 16 Aug 2019, In : Journal of Biological Chemistry. 294, 33, p. 12370-12379 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2018

A One-Pot "Triple-C" Multicyclization Methodology for the Synthesis of Highly Constrained Isomerically Pure Tetracyclic Peptides

Richelle, G. J. J., Schmidt, M., Ippel, H., Hackeng, T. M., van Maarseveen, J. H., Nuijens, T. & Timmerman, P., 17 Sep 2018, In : Chembiochem. 19, 18, p. 1934-1938 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Blocking CCL5-CXCL4 heteromerization preserves heart function after myocardial infarction by attenuating leukocyte recruitment and NETosis

Vajen, T., Koenen, R. R., Werner, I., Staudt, M., Projahn, D., Curaj, A., Sonmez, T. T., Simsekyilmaz, S., Schumacher, D., Mollmann, J., Hackeng, T. M., von Hundelshausen, P., Weber, C. & Liehn, E. A., 13 Jul 2018, In : Scientific Reports. 8, 11 p., 10647.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Factor V Has Anticoagulant Activity in Plasma in the Presence of TFPI: Difference between FV1 and FV2

van Doorn, P., Rosing, J., Duckers, C., Hackeng, T. M., Simioni, P. & Castoldi, E., 1 Jul 2018, In : Thrombosis and Haemostasis. 118, 7, p. 1194-1202 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Suppressive Role of Tissue Factor Pathway Inhibitor-alpha in Platelet-Dependent Fibrin Formation under Flow Is Restricted to Low Procoagulant Strength

Thomassen, S., Mastenbroek, T. G., Swieringa, F., Winckers, K., Feijge, M. A. H., Schrijver, R., Cosemans, J. M. E. M., Maroney, S. A., Mast, A. E., Hackeng, T. M. & Heemskerk, J. W. M., 1 Mar 2018, In : Thrombosis and Haemostasis. 118, 3, p. 502-513 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

2017

Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation

von Hundelshausen, P., Agten, S. M., Eckardt, V., Blanchet, X., Schmitt, M. M., Ippel, H., Neideck, C., Bidzhekov, K., Leberzammer, J., Wichapong, K., Faussner, A., Drechsler, M., Grommes, J., van Geffen, J. P., Li, H., Ortega-Gomez, A., Megens, R. T. A., Naumann, R., Dijkgraaf, I., Nicolaes, G. A. F. & 8 others, Doering, Y., Soehnlein, O., Lutgens, E., Heemskerk, J. W. M., Koenen, R. R., Mayo, K. H., Hackeng, T. M. & Weber, C., 5 Apr 2017, In : Science Translational Medicine. 9, 384, 14 p., eaah6650.

Research output: Contribution to journalArticleAcademicpeer-review

Coagulation factor and protease pathways in thrombosis and cardiovascular disease

ten Cate, H., Hackeng, T. M. & de Frutos, P. G., Jul 2017, In : Thrombosis and Haemostasis. 117, 7, p. 1265-1271 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Deletion of junctional adhesion molecule A from platelets increases early-stage neointima formation after wire injury in hyperlipidemic mice

Zhao, Z., Vajen, T., Karshovska, E., Dickhout, A., Schmitt, M. M., Megens, R. T. A., von Hundelshausen, P., Koeppel, T. A., Hackeng, T. M., Weber, C. & Koenen, R. R., Aug 2017, In : Journal of Cellular and Molecular Medicine. 21, 8, p. 1523-1531 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access

New functional assays to selectively quantify the activated protein C- and tissue factor pathway inhibitor-cofactor activities of protein S in plasma

Alshaikh, N. A., Rosing, J., Thomassen, M. C. L. G. D., Castoldi, E., Simioni, P. & Hackeng, T. M., May 2017, In : Journal of Thrombosis and Haemostasis. 15, 5, p. 950-960 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Omniligase-1: A Powerful Tool for Peptide Head-to-Tail Cyclization

Schmidt, M., Toplak, A., Quaedflieg, P. J. L. M., Ippel, H., Richelle, G. J. J., Hackeng, T. M., van Maarseveen, J. H. & Nuijens, T., 19 Jun 2017, In : Advanced Synthesis & Catalysis. 359, 12, p. 2050-2055 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Platelet full length TFPI-alpha in healthy volunteers is not affected by sex or hormonal use

Winckers, K., Thomassen, S., ten Cate, H. & Hackeng, T. M., 3 Feb 2017, In : PLOS ONE. 12, 2, 12 p., 0168273.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Prothrombin Loading of Vascular Smooth Muscle Cell-Derived Exosomes Regulates Coagulation and Calcification

Kapustin, A. N., Schoppet, M., Schurgers, L. J., Reynolds, J. L., McNair, R., Heiss, A., Jahnen-Dechent, W., Hackeng, T. M., Schlieper, G., Harrison, P. & Shanahan, C. M., Mar 2017, In : Arteriosclerosis Thrombosis and Vascular Biology. 37, 3, p. E22-E32 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The C-terminus of tissue factor pathway inhibitor-alpha inhibits factor V activation by protecting the Arg(1545) cleavage site

van Doorn, P., Rosing, J., Wielders, S. J., Hackeng, T. M. & Castoldi, E., Jan 2017, In : Journal of Thrombosis and Haemostasis. 15, 1, p. 140-149 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Use of Cyclic Backbone NGR-Based SPECT to Increase Efficacy of Postmyocardial Infarction Angiogenesis Imaging

Hendrikx, G., Hackeng, T. M., van Gorp, R., Bauwens, M., Schurgers, L. J., Mottaghy, F. M., Post, M. J. & Dijkgraaf, I., 2017, In : Contrast Media & Molecular Imaging. 2017, 9 p., 8638549.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Vascular CXCR4 Limits Atherosclerosis by Maintaining Arterial Integrity Evidence From Mouse and Human Studies

Doring, Y., Noels, H., van der Vorst, E. P. C., Neideck, C., Egea, V., Drechsler, M., Mandl, M., Pawig, L., Jansen, Y., Schroeder, K., Bidzhekov, K., Megens, R. T. A., Theelen, W., Klinkhammer, B. M., Boor, P., Schurgers, L., van Gorp, R., Ries, C., Kusters, P. J. H., van der Wal, A. & 11 others, Hackeng, T. M., Gaebel, G., Brandes, R. P., Soehnlein, O., Lutgens, E., Vestweber, D., Teupser, D., Holdt, L. M., Rader, D. J., Saleheen, D. & Weber, C., 25 Jul 2017, In : Circulation. 136, 4, p. 388-403 39 p.

Research output: Contribution to journalArticleAcademicpeer-review

Visualizing hepatocellular amino acid kinetics through mass spectrometry imaging of stable isotopes

Arts, M., Soons, Z., Dubois, L. J., Pierzchalski, K. A., Ellis, S. R., Balluff, B., Eijkel, G. B., Cramer, T., Lieuwes, N., Agten, S. M., Hackeng, T. M., Van Loon, L. J., Heeren, R. M. & Damink, S. W. O., 2017, In : Journal of Hepatology. 66, 1, p. S43-S44 2 p.

Research output: Contribution to journalConference Abstract/Poster in journalAcademic

2016

Binding of polysaccharides to human galectin-3 at a noncanonical site in its carbohydrate recognition domain

Miller, M. C., Ippel, H., Suylen, D., Klyosov, A. A., Traber, P. G., Hackeng, T. & Mayo, K. H., Jan 2016, In : Glycobiology. 26, 1, p. 88-99

Research output: Contribution to journalArticleAcademicpeer-review

Coated platelets function in platelet-dependent fibrin formation via integrin alpha(IIb)beta(3) and transglutaminase factor XIII

Mattheij, N. J. A., Swieringa, F., Mastenbroek, T. G., Berny-Lang, M. A., May, F., Baaten, C. C. F. M. J., van der Meijden, P. E. J., Henskens, Y. M. C., Beckers, E. A. M., Suylen, D. P. L., Nolte, M. W., Hackeng, T. M., McCarty, O. J. T., Heemskerk, J. W. M. & Cosemans, J. M. E. M., Apr 2016, In : Haematologica-the Hematology Journal. 101, 4, p. 427-436

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

CXCL1 microspheres: a novel tool to stimulate arteriogenesis

Caolo, V., Vries, M., Zupancich, J., Houben, M., Mihov, G., Wagenaar, A., Swennen, G., Nossent, Y., Quax, P., Suylen, D., Dijkgraaf, I., Molin, D., Hackeng, T. & Post, M., Oct 2016, In : Drug Delivery. 23, 8, p. 2919-2926

Research output: Contribution to journalArticleAcademicpeer-review

Deletion of junctional adhesion molecule a from platelets increases early stage neointima formation after wire injury in hyperlipidemic mice

Zhao, Z., Karshovska, E., Schmitt, M., Megens, R., Von Hundelshausen, P., Koeppel, T. A., Hackeng, T. M., Weber, C. & Koenen, R., 1 Jul 2016, p. S55-S55.

Research output: Contribution to conferenceAbstractAcademic

Intra- and intermolecular interactions of human galectin-3: assessment by full-assignment-based NMR

Ippel, H., Miller, M. C., Vertesy, S., Zheng, Y., Javier Canada, F., Suylen, D., Umemoto, K., Romano, C., Hackeng, T., Tai, G., Leffler, H., Kopitz, J., Andre, S., Kuebler, D., Jimenez-Barbero, J., Oscarson, S., Gabius, H-J. & Mayo, K. H., Aug 2016, In : Glycobiology. 26, 8, p. 888-903

Research output: Contribution to journalArticleAcademicpeer-review

Oxime Catalysis by Freezing

Agten, S. M., Suylen, D. P. L. & Hackeng, T. M., Jan 2016, In : Bioconjugate Chemistry. 27, 1, p. 42-46

Research output: Contribution to journalArticleAcademicpeer-review

Oxime conjugation in protein chemistry: from carbonyl incorporation to nucleophilic catalysis

Agten, S. M., Dawson, P. E. & Hackeng, T. M., May 2016, In : Journal of Peptide Science. 22, 5, p. 271-279

Research output: Contribution to journalArticleAcademicpeer-review

Probing Functional Heteromeric Chemokine Protein-Protein Interactions through Conformation-Assisted Oxime Ligation

Agten, S. M., Koenen, R. R., Ippel, H., Eckardt, V., von Hundelshausen, P., Mayo, K. H., Weber, C. & Hackeng, T. M., 21 Nov 2016, In : Angewandte Chemie-International Edition. 55, 48, p. 14963-14966

Research output: Contribution to journalArticleAcademicpeer-review

Role of exosite binding modulators in the inhibition of Fxa by TFPI

Peraramelli, S., Thomassen, S., Heinzmann, A., Hackeng, T. M., Hartmann, R., Scheiflinger, F., Dockal, M. & Rosing, J., Mar 2016, In : Thrombosis and Haemostasis. 115, 3, p. 580-590

Research output: Contribution to journalArticleAcademicpeer-review

Structure-Based Design of Peptidic Inhibitors of the Interaction between CC Chemokine Ligand 5 (CCL5) and Human Neutrophil Peptides 1 (HNP1)

Wichapong, K., Alard, J. -E., Ortega-Gomez, A., Weber, C., Hackeng, T. M., Soehnlein, O. & Nicolaes, G. A. F., 12 May 2016, In : Journal of Medicinal Chemistry. 59, 9, p. 4289-4301

Research output: Contribution to journalArticleAcademicpeer-review

Targeted vaccination against the bevacizumab binding site on VEGF using 3D-structured peptides elicits efficient antitumor activity

Wentink, M. Q., Hackeng, T. M., Tabruyn, S. P., Puijk, W. C., Schwamborn, K., Altschuh, D., Meloen, R. H., Schuurman, T., Griffioen, A. W. & Timmerman, P., 1 Nov 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 44, p. 12532-12537

Research output: Contribution to journalArticleAcademicpeer-review

2015

A novel approach for the intravenous delivery of leuprolide using core-cross-linked polymeric micelles

Hu, Q., van Gaal, E. V. B., Brundel, P., Ippel, H., Hackeng, T., Rijcken, C. J. F., Storm, G., Hennink, W. E. & Prakash, J., 10 May 2015, In : Journal of Controlled Release. 205, p. 98-108

Research output: Contribution to journalArticleAcademicpeer-review

Characterization of an autosomal dominant bleeding disorder caused by a thrombomodulin mutation

Dargaud, Y., Scoazec, J. Y., Wielders, S. J. H., Trzeciak, C., Hackeng, T. M., Negrier, C., Hemker, H. C., Lindhout, T. & Castoldi, E., 26 Feb 2015, In : Blood. 125, 9, p. 1497-1501

Research output: Contribution to journalArticleAcademicpeer-review

CXCL1 promotes arteriogenesis through enhanced monocyte recruitment into the peri-collateral space

Vries, M. H. M., Wagenaar, A., Verbruggen, S. E. L., Molin, D. G. M., Dijkgraaf, I., Hackeng, T. & Post, M. J., Apr 2015, In : Angiogenesis. 18, 2, p. 163-171

Research output: Contribution to journalArticleAcademicpeer-review

Discovery of Small Molecule CD40-TRAF6 Inhibitors

Zarzycka, B., Seijkens, T., Nabuurs, S. B., Ritschel, T., Grommes, J., Soehnlein, O., Schrijver, R., van Tiel, C. M., Hackeng, T. M., Weber, C., Giehler, F., Kieser, A., Lutgens, E., Vriend, G. & Nicolaes, G. A. F., Feb 2015, In : Journal of Chemical Information and Modeling. 55, 2, p. 294-307

Research output: Contribution to journalArticleAcademicpeer-review

H-1, C-13, and N-15 backbone and side-chain chemical shift assignments for the 36 proline-containing, full length 29 kDa human chimera-type galectin-3

Ippel, H., Miller, M. C., Berbis, M. A., Suylen, D., Andre, S., Hackeng, T. M., Canada, F. J., Weber, C., Gabius, H-J., Jimenez-Barbero, J. & Mayo, K. H., Apr 2015, In : Biomolecular Nmr Assignments. 9, 1, p. 59-63

Research output: Contribution to journalArticleAcademicpeer-review

Hyperreactivity of Junctional Adhesion Molecule A-Deficient Platelets Accelerates Atherosclerosis in Hyperlipidemic Mice

Karshovska, E., Zhao, Z., Blanchet, X., Schmitt, M. M. N., Bidzhekov, K., Soehnlein, O., von Hundelshausen, P., Mattheij, N. J., Cosemans, J. M. E. M., Megens, R. T. A., Koeppel, T. A., Schober, A., Hackeng, T. M., Weber, C. & Koenen, R. R., 13 Feb 2015, In : Circulation Research. 116, 4, p. 587-599

Research output: Contribution to journalArticleAcademicpeer-review

Molecular imaging of angiogenesis after myocardial infarction by (111)In-DTPA-cNGR and (99m)Tc-sestamibi dual-isotope myocardial SPECT

Hendrikx, G., De Saint-Hubert, M., Dijkgraaf, I., Bauwens, M., Douma, K., Wierts, R., Pooters, I., van den Akker, N. M., Hackeng, T. M., Post, M. J. & Mottaghy, F. M., 28 Jan 2015, In : EJNMMI Research. 5, p. 13-22 10 p., 2.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Molecular simulation studies of human coagulation factor VIII C domain-mediated membrane binding

Du, J., Wichapong, K., Hackeng, T. M. & Nicolaes, G. A. F., Feb 2015, In : Thrombosis and Haemostasis. 113, 2, p. 373-384

Research output: Contribution to journalArticleAcademicpeer-review

Recruitment of classical monocytes can be inhibited by disturbing heteromers of neutrophil HNP1 and platelet CCL5

Alard, J-E., Ortega-Gomez, A., Wichapong, K., Bongiovanni, D., Horckmans, M., Megens, R. T. A., Leoni, G., Ferraro, B., Rossaint, J., Paulin, N., Ng, J., Ippel, H., Suylen, D., Hinkel, R., Blanchet, X., Gaillard, F., D'Amico, M., von Hundelshausen, P., Zarbock, A., Scheiermann, C. & 6 others, Hackeng, T. M., Steffens, S., Kupatt, C., Nicolaes, G. A. F., Weber, C. & Soehnlein, O., 9 Dec 2015, In : Science Translational Medicine. 7, 317, 317ra196.

Research output: Contribution to journalArticleAcademicpeer-review

Theme 2: Epidemiology, Biomarkers, and Imaging of Venous Thromboembolism (and postthrombotic syndrome)

Spronk, H. M. H., Cannegieter, S., Morange, P., Hackeng, T., Huisman, M., Nagler, M., Posthuma, J., Ninivaggi, M., Zwaveling, S., van der Hulle, T., Scheres, L. J. J., van Mens, T. E. & Mackman, N., Sep 2015, In : Thrombosis Research. 136, p. S8-S12

Research output: Contribution to journalArticleAcademicpeer-review

Tissue factor-independent inhibition of thrombin generation by tissue factor pathway inhibitor-alpha

Thomassen, M. C. L. G. D., Heinzmann, A. C. A., Herfs, L., Hartmann, R., Dockal, M., Scheiflinger, F., Hackeng, T. M. & Rosing, J., Jan 2015, In : Journal of Thrombosis and Haemostasis. 13, 1, p. 92-100

Research output: Contribution to journalArticleAcademicpeer-review

2014

Atherogenic mononuclear cell recruitment is facilitated by oxidized lipoprotein-induced endothelial junctional adhesion molecule-A redistribution

Schmitt, M. M. N., Fraemohs, L., Hackeng, T. M., Weber, C. & Koenen, R. R., Jun 2014, In : Atherosclerosis. 234, 2, p. 254-264

Research output: Contribution to journalArticleAcademicpeer-review

Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance

Chatzigeorgioua, A., Seijkens, T., Zarzycka, B., Engel, D., Poggi, M., van den Berg, S., van den Berg, S., Soehnlein, O., Winkels, H., Beckers, L., Lievens, D., Driessen, A., Kusters, P., Biessen, E., Garcia-Martin, R., Ameln, A. K., Gijbels, M., Noelle, R., Boon, L., Hackeng, T. & 16 others, Schulte, K., Xu, A., Vriend, G., Nabuurs, S., Chung, K-J., van Dijk, K. W., Rensen, P. C. N., Gerdes, N., de Winther, M., Block, N. L., Schally, A. V., Weber, C., Bornstein, S. R., Nicolaes, G., Chavakis, T. & Lutgens, E., 18 Feb 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 7, p. 2686-2691

Research output: Contribution to journalArticleAcademicpeer-review

Controlled intramyocardial release of engineered chemokines by biodegradable hydrogels as a treatment approach of myocardial infarction

Projahn, D., Simsekyilmaz, S., Singh, S., Kanzler, I., Kramp, B. K., Langer, M., Burlacu, A., Bernhagen, J., Klee, D., Zernecke, A., Hackeng, T. M., Groll, J., Weber, C., Liehn, E. A. & Koenen, R. R., May 2014, In : Journal of Cellular and Molecular Medicine. 18, 5, p. 790-800

Research output: Contribution to journalArticleAcademicpeer-review

Endothelial Junctional Adhesion Molecule-A Guides Monocytes Into Flow-Dependent Predilection Sites of Atherosclerosis

Schmitt, M. M. N., Megens, R. T. A., Zernecke, A., Bidzhekov, K., van den Akker, N. M., Rademakers, T., van Zandvoort, M. A., Hackeng, T. M., Koenen, R. R. & Weber, C., 7 Jan 2014, In : Circulation. 129, 1, p. 66-+

Research output: Contribution to journalArticleAcademicpeer-review

Imaging evidence for endothelin ETA/ETB receptor heterodimers in isolated rat mesenteric resistance arteries

Kapsokalyvas, D., Schiffers, P. M. H., Maij, N., Suylen, D. P., Hackeng, T. M., van Zandvoort, M. A. M. J. & De Mey, J. G. R., 28 Aug 2014, In : Life Sciences. 111, 1-2, p. 36-41

Research output: Contribution to journalArticleAcademicpeer-review

Inhibition of tissue factor: factor VIIa-catalyzed factor IX and factor X activation by TFPI and TFPI constructs

Peraramelli, S., Thomassen, S., Heinzmann, A., Rosing, J., Hackeng, T. M., Hartmann, R., Scheiflinger, F. & Dockal, M., Nov 2014, In : Journal of Thrombosis and Haemostasis. 12, 11, p. 1826-1837

Research output: Contribution to journalArticleAcademicpeer-review