Synthesis of Constrained Tetracyclic Peptides by Consecutive CEPS, CLIPS, and Oxime Ligation

Dieuwertje E. Streefkerk; Marcel Schmidt; Johannes H. Ippel; Tilman M. Hackeng; Timo Nuijens; Peter Timmerman; Jan H. van Maarseveen

doi:10.1021/acs.orglett.9b00378

Synthesis of Constrained Tetracyclic Peptides by Consecutive CEPS, CLIPS, and Oxime Ligation

Dieuwertje E. Streefkerk, Marcel Schmidt, Johannes H. Ippel, Tilman M. Hackeng, Timo Nuijens, Peter Timmerman, Jan H. van Maarseveen^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	2095-2100
Number of pages	6
Journal	Organic Letters
Volume	21
Issue number	7
DOIs	https://doi.org/10.1021/acs.orglett.9b00378
Publication status	Published - 5 Apr 2019

Keywords

DISULFIDE-RICH PEPTIDES
MACROCYCLIZATION
CYCLIZATION
SYSTEM
SCAFFOLDS
HYBRIDS
SITE

Access to Document

10.1021/acs.orglett.9b00378

Cite this

Streefkerk, D. E., Schmidt, M., Ippel, J. H., Hackeng, T. M., Nuijens, T., Timmerman, P., & van Maarseveen, J. H. (2019). Synthesis of Constrained Tetracyclic Peptides by Consecutive CEPS, CLIPS, and Oxime Ligation. Organic Letters, 21(7), 2095-2100. https://doi.org/10.1021/acs.orglett.9b00378

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title = "Synthesis of Constrained Tetracyclic Peptides by Consecutive CEPS, CLIPS, and Oxime Ligation",

keywords = "DISULFIDE-RICH PEPTIDES, MACROCYCLIZATION, CYCLIZATION, SYSTEM, SCAFFOLDS, HYBRIDS, SITE",

author = "Streefkerk, {Dieuwertje E.} and Marcel Schmidt and Ippel, {Johannes H.} and Hackeng, {Tilman M.} and Timo Nuijens and Peter Timmerman and {van Maarseveen}, {Jan H.}",

year = "2019",

month = apr,

day = "5",

doi = "10.1021/acs.orglett.9b00378",

language = "English",

volume = "21",

pages = "2095--2100",

journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society",

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Synthesis of Constrained Tetracyclic Peptides by Consecutive CEPS, CLIPS, and Oxime Ligation. / Streefkerk, Dieuwertje E.; Schmidt, Marcel; Ippel, Johannes H.; Hackeng, Tilman M.; Nuijens, Timo; Timmerman, Peter; van Maarseveen, Jan H.

In: Organic Letters, Vol. 21, No. 7, 05.04.2019, p. 2095-2100.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Synthesis of Constrained Tetracyclic Peptides by Consecutive CEPS, CLIPS, and Oxime Ligation

AU - Streefkerk, Dieuwertje E.

AU - Schmidt, Marcel

AU - Ippel, Johannes H.

AU - Hackeng, Tilman M.

AU - Nuijens, Timo

AU - Timmerman, Peter

AU - van Maarseveen, Jan H.

PY - 2019/4/5

Y1 - 2019/4/5

KW - DISULFIDE-RICH PEPTIDES

KW - MACROCYCLIZATION

KW - CYCLIZATION

KW - SYSTEM

KW - SCAFFOLDS

KW - HYBRIDS

KW - SITE

U2 - 10.1021/acs.orglett.9b00378

DO - 10.1021/acs.orglett.9b00378

M3 - Article

VL - 21

SP - 2095

EP - 2100

JO - Organic Letters

JF - Organic Letters

SN - 1523-7060

IS - 7

ER -