Tick saliva protein Evasin-3 modulates chemotaxis by disrupting CXCL8 interactions with glycosaminoglycans and CXCR2

Stepan S. Denisov, Johannes H. Ippel, Alexandra C. A. Heinzmann, Rory R. Koenen, Mudena Ortega-Gomez, Oliver Soehnlein, Tilman M. Hackeng, Ingrid Dijkgraaf*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)12370-12379
Number of pages10
JournalJournal of Biological Chemistry
Volume294
Issue number33
DOIs
Publication statusPublished - 16 Aug 2019

Keywords

  • chemokine
  • peptide chemical synthesis
  • nuclear magnetic resonance (NMR)
  • protein structure
  • protein-protein interaction
  • C-X-C motif chemokine ligand (CXCL)
  • CHEMOKINE-BINDING-PROTEINS
  • CYSTINE KNOT
  • WEB SERVER
  • MONOCLONAL-ANTIBODY
  • RECEPTOR CXCR1
  • XPLOR-NIH
  • INTERLEUKIN-8
  • RECOGNITION
  • SELECTIVITY
  • STABILITY

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