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Research Output 1990 2018

  • 39 Article
  • 1 Book
  • 1 Comment/Letter to the editor
  • 1 Doctoral Thesis
2018

Allergens of permanent hair dyes induces epidermal damage, skin barrier loss and IL-1 alpha increase in epidermal in vitro model

Zanoni, T. B., Pedrosa, T. N., Catarino, C. M., Spiekstra, S. W., de Oliveira, D. P., Den Hartog, G., Bast, A., Hagemann, G., Gibbs, S., de Moraes Barros, S. B. & Maria-Engler, S. S., Feb 2018, In : Food and Chemical Toxicology. 112, p. 265-272 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Body mass index is negatively associated with telomere length: a collaborative cross-sectional meta-analysis of 87 observational studies

Gielen, M., Hageman, G. J., Antoniou, E. E., Nordfjall, K., Mangino, M., Balasubramanyam, M., de Meyer, T., Hendricks, A. E., Giltay, E. J., Hunt, S. C., Nettleton, J. A., Salpea, K. D., Diaz, V. A., Farzaneh-Far, R., Atzmon, G., Harris, S. E., Hou, L., Gilley, D., Hovatta, I., Kark, J. D. & 48 others, Nassar, H., Kurz, D. J., Mather, K. A., Willeit, P., Zheng, Y-L., Pavanello, S., Demerath, E. W., Rode, L., Bunout, D., Steptoe, A., Boardman, L., Marti, A., Needham, B., Zheng, W., Ramsey-Goldman, R., Pellatt, A. J., Kaprio, J., Hofmann, J. N., Gieger, C., Paolisso, G., Hjelmborg, J. B. H., Mirabello, L., Seeman, T., Wong, J., van der Harst, P., Broer, L., Kronenberg, F., Kollerits, B., Strandberg, T., Eisenberg, D. TA., Duggan, C., Verhoeven, J. E., Schaakxs, R., Zannolli, R., dos Reis, R. MR., Charchar, F. J., Tomaszewski, M., Mons, U., Demuth, I., Iglesias Molli, A. E., Cheng, G., Krasnienkov, D., D'Antono, B., Kasielski, M., McDonnell, B. J., Ebstein, R. P., Sundquist, K. & Zeegers, M. P., Sep 2018, In : American Journal of Clinical Nutrition. 108, 3, p. 453-475 23 p.

Research output: Contribution to journalArticleAcademicpeer-review

2017

Telomere tracking from birth to adulthood and residential traffic exposure

Bijnens, E. M., Zeegers, M. P., Derom, C., Martens, D. S., Gielen, M., Hageman, G. J., Plusquin, M., Thiery, E., Vlietinck, R. & Nawrot, T. S., 21 Nov 2017, In : BMC Medicine. 15, 10 p., 205.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access

The vitamin B6 paradox: Supplementation with high concentrations of pyridoxine leads to decreased vitamin B6 function

Vrolijk, M. F., Opperhuizen, A., Jansen, E. H. J. M., Hageman, G. J., Bast, A. & Haenen, G. R. M. M., Oct 2017, In : Toxicology in Vitro. 44, p. 206-212 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

2016
10 Citations (Scopus)

Various Mechanistic Pathways Representing the Aging Process Are Altered in COPD

Rutten, E., Gopal, P., Wouters, E. F., Franssen, F. M., Hageman, G. J., Vanfleteren, L. E., Spruit, M. A. & Reynaert, N. L., 1 Jan 2016, In : Chest. 149, 1, p. 53-61 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

2015
1 Citation (Scopus)

Lower placental telomere length may be attributed to maternal residential traffic exposure; a twin study

Bijnens, E., Zeegers, M. P., GIelen, M., Kicinski, M., Hageman, G. J., Pachen, D., Derom, C., Vlietinck, R. & Nawrot, T. S., Jun 2015, In : Environment International. 79, p. 1-7 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

The oxidation of p-phenylenediamine, an ingredient used for permanent hair dyeing purposes, leads to the formation of hydroxyl radicals: Oxidative stress and DNA damage in human immortalized keratinocytes

Zanoni, T. B., Hudari, F., Munnia, A., Peluso, M., Godschalk, R. W., Zanoni, M. V., den Hartog, G. J., Bast, A., Barros, S. B., Maria-Engler, S. S., Hageman, G. J. & de Oliveira, D. P., 15 Dec 2015, In : Toxicology Letters. 239, 3, p. 194-204 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

2014
7 Citations (Scopus)

Basic Red 51, a permitted semi-permanent hair dye, is cytotoxic to human skin cells: Studies in monolayer and 3D skin model using human keratinocytes (HaCaT)

Zanoni, T. B., Tiago, M., Faiao-Flores, F., Moraes de Barros, S. B., Bast, A., Hageman, G., de Oliveira, D. P. & Maria-Engler, S. S., 1 Jan 2014, In : Toxicology Letters. 227, 2, p. 139-149

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

Placental telomere length decreases with gestational age and is influenced by parity: A study of third trimester live-born twins

Gielen, M., Hageman, G., Pachen, D. M. F. A., Derom, C., Vlietinck, R. & Zeegers, M. P. A., Oct 2014, In : Placenta. 35, 10, p. 791-796 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

2013
9 Citations (Scopus)

Accelerated aging during chronic oxidative stress: a role for PARP-1

Boesten, D. M., de Vos-Houben, J. M., Timmermans, L., den Hartog, G. J., Bast, A. & Hageman, G. J., 1 Jan 2013, In : Oxidative Medicine and Cellular Longevity. 2013, 10 p., 680414.

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

Mild oxidative damage in the diabetic rat heart is attenuated by glyoxalase-1 overexpression

Brouwers, O., de Vos-Houben, J. M., Niessen, P. M., Miyata, T., van Nieuwenhoven, F., Janssen, B. J., Hageman, G., Stehouwer, C. D. & Schalkwijk, C. G., Aug 2013, In : International Journal of Molecular Sciences. 14, 8, p. 15724-15739 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

2012
10 Citations (Scopus)

Telomere length, oxidative stress, and antioxidant status in elderly men in Zutphen and Crete.

de Vos-Houben, J. M., Ottenheim, N. R., Kafatos, A., Buijsse, B., Hageman, G. J., Kromhout, D. & Giltay, E. J., Jun 2012, In : Mechanisms of Ageing and Development. 133, 6, p. 373-377 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

15 Citations (Scopus)

Telomere length and mental well-being in elderly men from the Netherlands and Greece.

Rius-Ottenheim, N., Houben, J. M., Kromhout, D., Kafatos, A., van de Mast, R. C., Zitman, F. G., Geleijnse, J. M., Hageman, G. J. & Giltay, E. J., Mar 2012, In : Behavior Genetics. 42, 2, p. 278-286 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

2011
19 Citations (Scopus)

A planar conformation and the hydroxyl groups in the b and c rings play a pivotal role in the antioxidant capacity of quercetin and quercetin derivatives

Moalin, M., van Strijdonck, G. P., Beckers, M., Hageman, G., Borm, P., Bast, A. & Haenen, G. R. M. M., Nov 2011, In : Molecules. 16, 11, p. 9636-9650 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

16 Citations (Scopus)

Decreased Exercise-Induced Expression of Nuclear Factor-{kappa}B-Regulated Genes in Muscle of Patients With COPD.

Mercken, E. M., Hageman, G. J., Langen, R. C. J., Wouters, E. F. M. & Schols, A. M. W. J., 1 Jan 2011, In : Chest. 139, 2, p. 337-346

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Spurious association between telomere length reduction over time and baseline telomere length.

Giltay, E. J., Hageman, G. J. & Kromhout, D., Jun 2011, In : International Journal of Epidemiology. 40, 3, p. 839-840 2 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

34 Citations (Scopus)

Telomere length and mortality in elderly men: the Zutphen Elderly Study

Houben, J. M., Giltay, E. J., Rius Ottenheim, N., Hageman, G. J. & Kromhout, D., 1 Jan 2011, In : Journals of Gerontology Series A-Biological Sciences and Medical Sciences. 66, 1, p. 38-44 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

2010
4 Citations (Scopus)

Inhibition of acute pulmonary and systemic inflammation by 1,7-dimethylxanthine.

Geraets, L., Haegens, A., Weseler, A. R., Brauers, K., Vernooy, J. H., Wouters, E. F., Bast, A. & Hageman, G. J., 10 Mar 2010, In : European Journal of Pharmacology. 629, 1-3, p. 132-139 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

2009
10 Citations (Scopus)

Dichloroacetate modulates the oxidative stress and inflammatory response to exercise in COPD.

Mercken, E. M., Calvert, L. D., Singh, S. J., Hageman, G. J., Schols, A. M. & Steiner, M. C., 1 Jan 2009, In : Chest. 36, 3, p. 744-751

Research output: Contribution to journalArticleAcademicpeer-review

45 Citations (Scopus)

Inhibition of LPS-induced pulmonary inflammation by specific flavonoids

Geraets, L., Haegens, A., Brauers, K., Haydock, J. A., Vernooy, J. H., Wouters, E. F., Bast, A. & Hageman, G. J., 1 Jan 2009, In : Biochemical and Biophysical Research Communications. 382, 3, p. 598-603

Research output: Contribution to journalArticleAcademicpeer-review

24 Citations (Scopus)

Poly (ADP-ribose) Polymerase-1-Inhibiting Flavonoids Attenuate Cytokine Release in Blood from Male Patients with Chronic Obstructive Pulmonary Disease or Type 2 Diabetes

Weseler, A. R., Geraets, L., Moonen, H. J., Manders, R. J., van Loon, L. J., Pennings, H. J., Wouters, E. F., Bast, A. & Hageman, G. J., 1 Jan 2009, In : Journal of Nutrition. 139, 5, p. 952-957

Research output: Contribution to journalArticleAcademicpeer-review

20 Citations (Scopus)

Systemic and Pulmonary Oxidative Stress After Single-Leg Exercise in COPD

Mercken, E. M., Gosker, H. R., Rutten, E. P., Wouters, E. F., Bast, A., Hageman, G. J. & Schols, A. M., 1 Jan 2009, In : Chest. 136, 5, p. 1291-1300

Research output: Contribution to journalArticleAcademicpeer-review

66 Citations (Scopus)

Telomere shortening in chronic obstructive pulmonary disease.

Houben, J. M., Mercken, E. M., Ketelslegers, H. B., Bast, A., Wouters, E. F., Hageman, G. J. & Schols, A. M., 1 Jan 2009, In : Respiratory Medicine. 103, 2, p. 230-236

Research output: Contribution to journalArticleAcademicpeer-review

2008

Sanapolis: de gezonde stad

Savelberg, H. H. C. M., van Baak, M. A., Hageman, G. J., Kempen, G. I. J. M., Maarse, J. A. M., de Rijk, A. E. & Vlaeyen, J. W. S., 1 Jan 2008, Maastricht: Maastricht University, Faculty of Health, Medicine and Life Sciences.

Research output: Book/ReportBookPopular

212 Citations (Scopus)

Telomere length assessment: Biomarker of chronic oxidative stress?

Houben, J. M., Moonen, H. J., van Schooten, F. J. & Hageman, G. J., 1 Jan 2008, In : Free Radical Biology and Medicine. 44, 3, p. 235-246

Research output: Contribution to journalArticleAcademicpeer-review

2007
60 Citations (Scopus)

Dietary Flavones and Flavonoles Are Inhibitors of Poly(ADP-ribose)polymerase-1 in Pulmonary Epithelial Cells.

Geraets, L., Moonen, H. J., Brauers, K., Wouters, E. F., Bast, A. & Hageman, G. J., 1 Jan 2007, In : Journal of Nutrition. 137, 10, p. 2190-2195

Research output: Contribution to journalArticleAcademicpeer-review

14 Citations (Scopus)

Flavone as PARP-1 inhibitor: its effect on lipopolysaccharide induced gene-expression.

Geraets, L., Moonen, H. J., Brauers, K., Gottschalk, R. W., Wouters, E. F., Bast, A. & Hageman, G. J., 1 Jan 2007, In : European Journal of Pharmacology. 473, 1-3, p. 241-248

Research output: Contribution to journalArticleAcademicpeer-review

2006
56 Citations (Scopus)

Caffeine metabolites are inhibitors of the nuclear enzyme poly(ADP-ribose)polymerase-1 at physiological concentrations.

Geraets, L., Moonen, H. J., Wouters, E. F., Bast, A. & Hageman, G. J., 1 Jan 2006, In : Biochemical Pharmacology. 72, 7, p. 902-910

Research output: Contribution to journalArticleAcademicpeer-review

23 Citations (Scopus)

Plasma ectonucleotidases prevent desensitization of purinergic receptors in stored platelets: importance for platelet activity during thrombus formation

Cauwenberghs, S., Feijge, M. A., Hageman, G., Hoylaerts, M., Akkerman, J. W., Curvers, J. & Heemskerk, J. W., 1 Jan 2006, In : Transfusion. 46, 6, p. 1018-1028

Research output: Contribution to journalArticleAcademicpeer-review

2005
82 Citations (Scopus)

Poly(ADP-ribose) polymerase-1 mediated caspase-independent cell death after ischemia/reperfusion

van Wijk, S. J. & Hageman, G. J., 1 Jan 2005, In : Free Radical Biology and Medicine. 39, 1, p. 81-90

Research output: Contribution to journalArticleAcademicpeer-review

120 Citations (Scopus)

Rehabilitation Decreases Exercise-induced Oxidative Stress in Chronic Obstructive Pulmonary Disease

Mercken, E. M., Hageman, G. J., Schols, A. M., Akkermans, M. A., Bast, A. & Wouters, E. F., 1 Jan 2005, In : American Journal of Respiratory and Critical Care Medicine. 172, 8, p. 994-1001

Research output: Contribution to journalArticleAcademicpeer-review

30 Citations (Scopus)

Theophylline prevents NAD(+) depletion via PARP-1 inhibition in human pulmonary epithelial cells

Moonen, H. J., Geraets, L., Vaarhorst, A., Bast, A., Wouters, E. F. & Hageman, G. J., 1 Jan 2005, In : Biochemical and Biophysical Research Communications. 338, 4, p. 1805-1810

Research output: Contribution to journalArticleAcademicpeer-review

2003
47 Citations (Scopus)

Systemic poly(ADP-ribose) polymerase-1 activation, chronic inflammation, and oxidative stress in COPD patients

Hageman, G. J., Larik, I., Pennings, H. J., Haenen, G. R. M. M., Wouters, E. F. M. & Bast, A., 1 Jan 2003, In : Free Radical Biology and Medicine. 35, 2, p. 140-148 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

2001
4 Citations (Scopus)

Biomonitoring the intake of garlic via urinary excretion of allyl mercapturic acid.

Verhagen, H., Hageman, G. J., Rauma, A. L., Versluis-de Haan, G., van Herwijnen, M. H. M., de Groot, J., Torronen, R. & Mykkanen, H., 1 Jan 2001, In : Journal of Nutrition. 86 suppl 1, p. S111-S114 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

92 Citations (Scopus)

Niacin, poly(ADP-ribose) polymerase-1 and genomic stability

Hageman, G. J. & Stierum, R. H., 1 Jan 2001, In : Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis. 475, (1-2), p. 45-56 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

2000
68 Citations (Scopus)

Synthesis of novel 3,7-substituted-2-(3',4'-dihydroxyphenyl)flavones with improved antioxidant activity

van Acker, F. A. A., Hageman, G. J., Haenen, G. R. M. M., van der Vijgh, W. J. F., Bast, A. & Menge, W. M. P. B., 1 Jan 2000, In : Journal of Medicinal Chemistry. 43, p. 3752-3760 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

1999
72 Citations (Scopus)

Antibacterial effect of garlic and omeprazole on Helicobacter pylori.

Jonkers, D. M. A. E., van den Broek, E., van Dooren, I. M. A., Thijs, C. T. M., Dorant, E., Hageman, G. J. & Stobberingh, E. E., 1 Jan 1999, In : Journal of Antimicrobial Chemotherapy. 43, 6, p. 837-839 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

1998
11 Citations (Scopus)

Nicotinic acid supplementation: effects on niacin status, cytogenetic damage, and poly(ADP-ribosylation) in lymphocytes of smokers.

Hageman, G. J., Stierum, R. H., van Herwijnen, M. H. M., van der Veer, M. S. & Kleinjans, J. C. S., 1 Jan 1998, In : Nutrition and Cancer-An International Journal. 32, 2, p. 113-120 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

1996

Nitrate contamination of drinking water: relationship with HPRT variant frequency in lymphocyte DNA and urinary excretion of N-nitrosamines

van Maanen, J. M. S., Welle, I. J., Hageman, G. J., Dallinga, J. W., Mertens, P. L. & Kleinjans, J. C. S., 1 Jan 1996, In : Environmental Health Perspectives. 104, 5, p. 522-529

Research output: Contribution to journalArticleAcademicpeer-review

1990
165 Downloads (Pure)

Heat-processed fats : analysis of genotoxicity

Hageman, G. J., 1 Jan 1990, Maastricht: Rijksuniversiteit Limburg.

Research output: ThesisDoctoral ThesisInternal

Open Access
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