If you made any changes in Pure these will be visible here soon.

Research Output 2008 2019

2019

Heterogeneity and plasticity in healthy and atherosclerotic vasculature explored by single-cell sequencing

van Kuijk, K., Kuppe, C., Betsholtz, C., Vanlandewijck, M., Kramann, R. & Sluimer, J. C., 1 Oct 2019, In : Cardiovascular Research. 115, 12, p. 1705-1715 11 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Integrative Multi-Omics Analysis Of Human Atherosclerosis Reveals An Intraplaque Bleeding Associated Network, Which Offers Better Prediction Of Disease Stage

Jin, H., Goossens, P., Karel, J., Daemen, M., Sluimer, J. & Biessen, E., 3 Aug 2019, In : Atherosclerosis. 287, p. e63-e63 1 p., EAS19-0625.

Research output: Contribution to journalConference Abstract/Poster in journalAcademic

Joint ESM-EVBO meetings: past, present, and future

Sluimer, J. C. & Houben, A. J. H. M., 15 Mar 2019, In : Cardiovascular Research. 115, 4, p. E46-E48 3 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Low human and murine Mcl-1 expression leads to a pro-apoptotic plaque phenotype enriched in giant-cells

Fontaine, M. A. C., Westra, M. M., Bot, I., Jin, H., Franssen, A. J. P. M., Bot, M., de Jager, S. C. A., Dzhagalov, I., He, Y-W., van Vlijmen, B. J. M., Gijbels, M. J. J., Reutelingsperger, C. P., van Berkel, T. J. C., Sluimer, J. C., Temmerman, L. & Biessen, E. A. L., 10 Oct 2019, In : Scientific Reports. 9, 11 p., 14547.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The Human-Specific and Smooth Muscle Cell-Enriched LncRNA SMILR Promotes Proliferation by Regulating Mitotic CENPF mRNA and Drives Cell-Cycle Progression Which Can Be Targeted to Limit Vascular Remodeling

Mahmoud, A. D., Ballantyne, M. D., Miscianinov, V., Pinel, K., Hung, J., Scanlon, J. P., Iyinikkel, J., Kaczynski, J., Tavares, A. S., Bradshaw, A. C., Mills, N. L., Newby, D. E., Caporali, A., Gould, G. W., George, S. J., Ulitsky, I., Sluimer, J. C., Rodor, J. & Baker, A. H., 16 Aug 2019, In : Circulation Research. 125, 5, p. 535-551 17 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2018

Future directions for therapeutic strategies in post-ischaemic vascularization: a position paper from European Society of Cardiology Working Group on Atherosclerosis and Vascular Biology

Caporali, A., Back, M., Daemen, M. J., Hoefer, I. E., Jones, E. A., Lutgens, E., Matter, C. M., Bochaton-Piallat, M-L., Siekmann, A. F., Sluimer, J. C., Steffens, S., Tunon, J., Vindis, C., Wentzel, J. J., Yla-Herttuala, S. & Evans, P. C., 1 Sep 2018, In : Cardiovascular Research. 114, 11, p. 1411-1421 11 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Targeting Non-coding RNA in Vascular Biology and Disease

Hung, J., Miscianinov, V., Sluimer, J. C., Newby, D. E. & Baker, A. H., 22 Nov 2018, In : Frontiers in physiology. 9, 16 p., 1655.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Unravelling atherosclerotic heterogeneity by single cell RNA sequencing

McCracken, I. R., Taylor, R. S., Henderson, N. C., Sluimer, J. C. & Baker, A. H., Dec 2018, In : Current Opinion in Lipidology. 29, 6, p. 488-489 2 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Vasa Vasorum Angiogenesis: Key Player in the Initiation and Progression of Atherosclerosis and Potential Target for the Treatment of Cardiovascular Disease

Sedding, D. G., Boyle, E. C., Demandt, J. A. F., Sluimer, J. C., Dutzmann, J., Haverich, A. & Bauersachs, J., 17 Apr 2018, In : Frontiers in Immunology. 9, 14 p., 706.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
2017

Atherosclerosis development: lipoproteins and beyond

van Kuijk, K., Baker, A. H. & Sluimer, J. C., Dec 2017, In : Current Opinion in Lipidology. 28, 6, p. 520-521 2 p.

Research output: Contribution to journalEditorialAcademicpeer-review

CAMKIIγ suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosis

Doran, A. C., Ozcan, L., Cai, B., Zheng, Z., Fredman, G., Rymond, C. C., Dorweiler, B., Sluimer, J. C., Hsieh, J., Kuriakose, G., Tall, A. R. & Tabas, I., 1 Nov 2017, In : Journal of Clinical Investigation. 127, 11, p. 4075-4089 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Differential regulation of angiogenic cellular processes and claudin-5 by histamine and VEGF via PI3K-signaling, transcription factor SNAI2 and interleukin-8

Laakkonen, J. P., Lappalainen, J. P., Theelen, T. L., Toivanen, P. I., Nieminen, T., Jauhiainen, S., Kaikkonen, M. U., Sluimer, J. C. & Yla-Herttuala, S., Feb 2017, In : Angiogenesis. 20, 1, p. 109-124 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Feasibility of in vivo (18)F-florbetaben PET/MR imaging of human carotid amyloid-beta

Bucerius, J., Barthel, H., Tiepolt, S., Werner, P., Sluimer, J. C., Wildberger, J. E., Patt, M., Hesse, S., Gertz, H-J., Biessen, E. A. L., Mottaghy, F. M. & Sabri, O., Jul 2017, In : European Journal of Nuclear Medicine and Molecular Imaging. 44, 7, p. 1119-1128 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Heart rate lowering treatment leads to a reduction in vulnerable plaque features in atherosclerotic rabbits

van Hoof, R. H. M., Hermeling, E., Sluimer, J. C., Salzmann, J., Hoeks, A. P. G., Roussel, J., Daemen, M. J. A. P., Struijker-Boudier, H., Wildberger, J. E., Heeneman, S. & Kooi, M. E., 22 Jun 2017, In : PLOS ONE. 12, 6, 17 p., 0179024.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Vascular Imaging With 18F-Fluorodeoxyglucose Positron Emission Tomography Is Influenced by Hypoxia

Joshi, F. R., Manavaki, R., Fryer, T. D., Figg, N. L., Sluimer, J. C., Aigbirhio, F. I., Davenport, A. P., Kirkpatrick, P. J., Warburton, E. A. & Rudd, J. H. F., 11 Apr 2017, In : Journal of the American College of Cardiology. 69, 14, p. 1873-1874 2 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

Open Access

Vessel Wall and Adventitial DCE-MRI Parameters Demonstrate Similar Correlations With Carotid Plaque Microvasculature on Histology

van Hoof, R. H. M., Voo, S. A., Sluimer, J. C., Wijnen, N. J. A., Hermeling, E., Schreuder, F. H. B. M., Truijman, M. T. B., Cleutjens, J. P. M., Daemen, M. J. A. P., Daemen, J-W. H., van Oostenbrugge, R. J., Mess, W. H., Wildberger, J. E., Heeneman, S. & Kooi, M. E., Oct 2017, In : Journal of Magnetic Resonance Imaging. 46, 4, p. 1053-1059 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Whole body and hematopoietic ADAM8 deficiency does not influence advanced atherosclerotic lesion development, despite its association with human plaque progression

Theodorou, K., van der Vorst, E. P. C., Gijbels, M. J., Wolfs, I. M. J., Jeurissen, M., Theelen, T. L., Sluimer, J. C., Wijnands, E., Cleutjens, J. P., Li, Y., Jansen, Y., Weber, C., Ludwig, A., Bentzon, J. F., Bartsch, J. W., Biessen, E. A. L. & Donners, M. M. P. C., 15 Sep 2017, In : Scientific Reports. 7, 11 p., 11670.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2016

Cardiac Troponin T and I Release After a 30-km Run

Klinkenberg, L. J. J., Luyten, P., van der Linden, N., Urgel, K., Snijders, D. P. C., Knackstedt, C., Dennert, R., Kietselaer, B. L. J. H., Mingels, A., Cardinaels, E. P. M., Peeters, F. E. C. M., van Suijlen, J. D. E., ten Kate, J., Marsch, E., Theelen, T. L., Sluimer, J. C., Wouters, K., Bekers, O., Bekkers, B., van Loon, L. & 2 others, Visser - van Dieijen, M. & Meex, S. J. R., 15 Jul 2016, In : American Journal of Cardiology. 118, 2, p. 281-287

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
4 Citations (Scopus)

Deficiency of the oxygen sensor prolyl hydroxylase 1 attenuates hypercholesterolaemia, atherosclerosis, and hyperglycaemia

Marsch, E., Demandt, J. A. F., Theelen, T. L., Tullemans, B. M. E., Wouters, K., Boon, M. R., van Dijk, T. H., Gijbels, M. J., Dubois, L. J., Meex, S. J. R., Mazzone, M., Hung, G., Fisher, E. A., Biessen, E. A. L., Daemen, M. J. A. P., Rensen, P. C. N., Carmeliet, P., Groen, A. K. & Sluimer, J. C., 14 Oct 2016, In : European Heart Journal. 37, 39, p. 2993-2997

Research output: Contribution to journalArticleAcademicpeer-review

QUANTIFICATION OF ENDOTHELIAL alpha(V)beta(3) EXPRESSION WITH HIGH-FREQUENCY ULTRASOUND AND TARGETED MICROBUBBLES: IN VITRO AND IN VIVO STUDIES

Daeichin, V., Kooiman, K., Skachkov, I., Bosch, J. G., Theelen, T. L., Steiger, K., Needles, A., Janssen, B. J., Daemen, M. J. A. P., van der Steen, A. F. W., de Jong, N. & Sluimer, J. C., Sep 2016, In : Ultrasound in Medicine and Biology. 42, 9, p. 2283-2293

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

THSD1 preserves vascular integrity and protects against intraplaque haemorrhaging in ApoE(-/-) mice

Haasdijk, R. A., Den Dekker, W. K., Cheng, C., Tempel, D., Szulcek, R., Bos, F. L., Hermkens, D. M. A., Chrifi, I., Brandt, M. M., Van Dijk, C., Xu, Y. J., Van De Kamp, E. H. M., Blonden, L. A. J., Van Bezu, J., Sluimer, J. C., Biessen, E. A. L., Amerongen, G. P. V. N. & Duckers, H. J., 1 May 2016, In : Cardiovascular Research. 110, 1, p. 129-139

Research output: Contribution to journalArticleAcademicpeer-review

2015
3 Citations (Scopus)

Ablation of CD8 alpha(+) dendritic cell mediated cross-presentation does not impact atherosclerosis in hyperlipidemic mice

Legein, B., Janssen, E. M., Theelen, T. L., Gijbels, M. J., Walraven, J., Klarquist, J. S., Hennies, C. M., Wouters, K., Seijkens, T. T. P., Wijnands, E., Sluimer, J. C., Lutgens, E., Zenke, M., Hildner, K., Biessen, E. A. L. & Temmerman, L., 21 Oct 2015, In : Scientific Reports. 5, 15414.

Research output: Contribution to journalArticleAcademicpeer-review

9 Citations (Scopus)

Angiopoietin-2 blocking antibodies reduce early atherosclerotic plaque development in mice

Theelen, T. L., Lappalainen, J. P., Sluimer, J. C., Gurzeler, E., Cleutjens, J. P., Gijbels, M. J., Biessen, E. A. L., Daemen, M. J. A. P., Alitalo, K. & Yla-Herttuala, S., Aug 2015, In : Atherosclerosis. 241, 2, p. 297-304

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Deficiency of HIF1 alpha in Antigen-Presenting Cells Aggravates Atherosclerosis and Type 1 T-Helper Cell Responses in Mice

Chaudhari, S. M., Sluimer, J. C., Koch, M., Theelen, T. L., Manthey, H. D., Busch, M., Caballero-Franco, C., Vogel, F., Cochain, C., Pelisek, J., Daemen, M. J., Lutz, M. B., Goerlach, A., Kissler, S., Hermanns, H. M. & Zernecke, A., Nov 2015, In : Arteriosclerosis Thrombosis and Vascular Biology. 35, 11, p. 2316-2325

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Detection of Intraplaque Hemorrhage in Mouse Atherosclerotic Lesions

Sluimer, J. C., Gijbels, M. J. & Heeneman, S., 2015, In : Methods in molecular biology. 1339, p. 339-48 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

33 Citations (Scopus)

Elastin fragmentation inatheroscleroticmice leads to intraplaque neovascularization, plaque rupture, myocardial infarction, stroke, and sudden death

Van der Donckt, C., Van Herck, J. L., Schrijvers, D. M., Vanhoutte, G., Verhoye, M., Blockx, I., Van Der Linden, A., Bauters, D., Lijnen, H. R., Sluimer, J. C., Roth, L., Van Hove, C. E., Fransen, P., Knaapen, M. W., Hervent, A-S., De Keulenaer, G. W., Bult, H., Martinet, W., Herman, A. G. & De Meyer, G. R. Y., 1 May 2015, In : European Heart Journal. 36, 17, p. 1049-1058A

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Hck/Fgr Kinase Deficiency Reduces Plaque Growth and Stability by Blunting Monocyte Recruitment and Intraplaque Motility

Medina, I., Cougoule, C., Drechsler, M., Bermudez, B., Koenen, R. R., Sluimer, J., Wolfs, I., Doering, Y., Herias, V., Gijbels, M., Bot, I., de Jager, S. C. A., Weber, C., Cleutjens, J., van Berkel, T. J. C., Sikkink, K-J., Mocsai, A., Maridonneau-Parini, I., Soehnlein, O. & Biessen, E. A. L., 11 Aug 2015, In : Circulation. 132, 6, p. 490-501

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

In Vivo Imaging of Hypoxia in Atherosclerotic Plaques in Humans

van der Valk, F. M., Sluimer, J. C., Voo, S. A., Verberne, H. J., Nederveen, A. J., Windhorst, A. D., Stroes, E. S. G., Lambin, P. & Daemen, M. J. A. P., Nov 2015, In : JACC-Cardiovascular Imaging. 8, 11, p. 1340-1341

Research output: Contribution to journalArticleAcademicpeer-review

Live Observation of Atherosclerotic Plaque Disruption in Apolipoprotein E-Deficient Mouse

Daeichin, V., Sluimer, J. C., van der Heiden, K., Skachkov, I., Kooiman, K., Janssen, A., Janssen, B., Bosch, J. G., de Jong, N., Daemen, M. J. A. P. & van der Steen, A. F. W., Nov 2015, In : Ultrasound international open. 1, 2, p. E67-71

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

Quantification of Bound Microbubbles in Ultrasound Molecular Imaging

Daeichin, V., Akkus, Z., Skachkov, I., Kooiman, K., Needles, A., Sluimer, J., Janssen, B., Daemen, M. J. A. P., van der Steen, A. F. W., de Jong, N. & Bosch, J. G., Jun 2015, In : Ieee Transactions on Ultrasonics Ferroelectrics and Frequency Control. 62, 6, p. 1190-1200

Research output: Contribution to journalArticleAcademicpeer-review

Staging Lymphocyte Presence in Human Atherosclerosis: A Tale Told by Numbers

Biessen, E. A. L. & Sluimer, J. C., Apr 2015, In : Journal of the American Heart Association. 4, 4, e001909.

Research output: Contribution to journalArticleAcademicpeer-review

2014
18 Citations (Scopus)

CXCR4 blockade induces atherosclerosis by affecting neutrophil function

Bot, I., Daissormont, I. T. M. N., Zernecke, A., van Puijvelde, G. H. M., Kramp, B., de Jager, S. C. A., Sluimer, J. C., Manca, M., Herias, V., Westra, M. M., Bot, M., van Santbrink, P. J., van Berkel, T. J. C., Su, L., Skjelland, M., Gullestad, L., Kuiper, J., Halvorsen, B., Aukrust, P., Koenen, R. R. & 2 others, Weber, C. & Biessen, E. A. L., Sep 2014, In : Journal of Molecular and Cellular Cardiology. 74, p. 44-52

Research output: Contribution to journalArticleAcademicpeer-review

40 Citations (Scopus)

Higher levels of advanced glycation endproducts in human carotid atherosclerotic plaques are associated with a rupture-prone phenotype

Hanssen, N. M. J., Wouters, K., Huijberts, M. S., Gijbels, M. J., Sluimer, J. C., Scheijen, J. L. J. M., Heeneman, S., Biessen, E. A. L., Daemen, M. J. A. P., Brownlee, M., de Kleijn, D. P., Stehouwer, C. D. A., Pasterkamp, G. & Schalkwijk, C. G., May 2014, In : European Heart Journal. 35, 17, p. 1137-1146

Research output: Contribution to journalArticleAcademicpeer-review

2013
30 Citations (Scopus)

Dynamic Contrast-enhanced MR Imaging of Carotid Atherosclerotic Plaque: Model Selection, Reproducibility, and Validation.

Gaens, M. E., Backes, W. H., Rozel, S., Lipperts, M., Sanders, S. N., Jaspers, K., Cleutjens, J. P. M., Sluimer, J. C., Heeneman, S., Daemen, M. J. A. P., Welten, R. J., Daemen, J. W., Wildberger, J. E., Kwee, R. M. & Kooi, M. E., 1 Jan 2013, In : Radiology. 266, 1, p. 271-279 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Hypoxia in atherosclerosis and inflammation

Marsch, E., Sluimer, J. C. & Daemen, M. J. A. P., Oct 2013, In : Current Opinion in Lipidology. 24, 5, p. 393-400

Research output: Contribution to journalArticleAcademicpeer-review

2012

Macrophage Autophagy Plays a Protective Role in Advanced Atherosclerosis

Liao, X., Sluimer, J. C., Wang, Y-J., Subramanian, M., Brown, K., Pattison, J. S., Robbins, J., Martinez, J. & Tabas, I., 4 Apr 2012, In : Cell Metabolism. 15, 4, p. 545-553

Research output: Contribution to journalArticleAcademicpeer-review

2010

Renal ACE2 expression and activity is unaltered during established hypertension in adult SHRSP and TGR(mREN2)27

Kamilic, J., Hamming, I., Kreutz, R., Bolbrinker, J., Siems, W-E., Nassar, I., Sluimer, J. C., Walther, T., Navis, G. J. & van Goor, H., Feb 2010, In : Hypertension Research. 33, 2, p. 123-128

Research output: Contribution to journalArticleAcademicpeer-review

2008
225 Downloads (Pure)

Hypoxia, HIF and angiogenesis in atherosclerosis

Sluimer, J. C., 1 Jan 2008, Maastricht: Datawyse / Universitaire Pers Maastricht. 218 p.

Research output: ThesisDoctoral ThesisInternal

Open Access
File