The Human-Specific and Smooth Muscle Cell-Enriched LncRNA SMILR Promotes Proliferation by Regulating Mitotic CENPF mRNA and Drives Cell-Cycle Progression Which Can Be Targeted to Limit Vascular Remodeling

Amira D. Mahmoud; Margaret D. Ballantyne; Vladislav Miscianinov; Karine Pinel; John Hung; Jessica P. Scanlon; Jean Iyinikkel; Jakub Kaczynski; Adriana S. Tavares; Angela C. Bradshaw; Nicholas L. Mills; David E. Newby; Andrea Caporali; Gwyn W. Gould; Sarah J. George; Igor Ulitsky; Judith C. Sluimer; Julie Rodor; Andrew H. Baker

doi:10.1161/CIRCRESAHA.119.314876

The Human-Specific and Smooth Muscle Cell-Enriched LncRNA SMILR Promotes Proliferation by Regulating Mitotic CENPF mRNA and Drives Cell-Cycle Progression Which Can Be Targeted to Limit Vascular Remodeling

Amira D. Mahmoud, Margaret D. Ballantyne, Vladislav Miscianinov, Karine Pinel, John Hung, Jessica P. Scanlon, Jean Iyinikkel, Jakub Kaczynski, Adriana S. Tavares, Angela C. Bradshaw, Nicholas L. Mills, David E. Newby, Andrea Caporali, Gwyn W. Gould, Sarah J. George, Igor Ulitsky, Judith C. Sluimer, Julie Rodor, Andrew H. Baker^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	535-551
Number of pages	17
Journal	Circulation Research
Volume	125
Issue number	5
DOIs	https://doi.org/10.1161/CIRCRESAHA.119.314876
Publication status	Published - 16 Aug 2019

Keywords

blood vessels
cell cycle
growth factors
interleukins
muscle cells
noncoding RNA
saphenous vein
LONG NONCODING RNA
EXPRESSION
MIGRATION
STENTS
DIFFERENTIATION
PROGNOSIS
NETWORKS
BIOLOGY

Access to Document

10.1161/CIRCRESAHA.119.314876

Cite this

Mahmoud, A. D., Ballantyne, M. D., Miscianinov, V., Pinel, K., Hung, J., Scanlon, J. P., Iyinikkel, J., Kaczynski, J., Tavares, A. S., Bradshaw, A. C., Mills, N. L., Newby, D. E., Caporali, A., Gould, G. W., George, S. J., Ulitsky, I., Sluimer, J. C., Rodor, J., & Baker, A. H. (2019). The Human-Specific and Smooth Muscle Cell-Enriched LncRNA SMILR Promotes Proliferation by Regulating Mitotic CENPF mRNA and Drives Cell-Cycle Progression Which Can Be Targeted to Limit Vascular Remodeling. Circulation Research, 125(5), 535-551. https://doi.org/10.1161/CIRCRESAHA.119.314876

Mahmoud, Amira D. ; Ballantyne, Margaret D. ; Miscianinov, Vladislav ; Pinel, Karine ; Hung, John ; Scanlon, Jessica P. ; Iyinikkel, Jean ; Kaczynski, Jakub ; Tavares, Adriana S. ; Bradshaw, Angela C. ; Mills, Nicholas L. ; Newby, David E. ; Caporali, Andrea ; Gould, Gwyn W. ; George, Sarah J. ; Ulitsky, Igor ; Sluimer, Judith C. ; Rodor, Julie ; Baker, Andrew H. / The Human-Specific and Smooth Muscle Cell-Enriched LncRNA SMILR Promotes Proliferation by Regulating Mitotic CENPF mRNA and Drives Cell-Cycle Progression Which Can Be Targeted to Limit Vascular Remodeling. In: Circulation Research. 2019 ; Vol. 125, No. 5. pp. 535-551.

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title = "The Human-Specific and Smooth Muscle Cell-Enriched LncRNA SMILR Promotes Proliferation by Regulating Mitotic CENPF mRNA and Drives Cell-Cycle Progression Which Can Be Targeted to Limit Vascular Remodeling",

keywords = "blood vessels, cell cycle, growth factors, interleukins, muscle cells, noncoding RNA, saphenous vein, LONG NONCODING RNA, EXPRESSION, MIGRATION, STENTS, DIFFERENTIATION, PROGNOSIS, NETWORKS, BIOLOGY",

author = "Mahmoud, {Amira D.} and Ballantyne, {Margaret D.} and Vladislav Miscianinov and Karine Pinel and John Hung and Scanlon, {Jessica P.} and Jean Iyinikkel and Jakub Kaczynski and Tavares, {Adriana S.} and Bradshaw, {Angela C.} and Mills, {Nicholas L.} and Newby, {David E.} and Andrea Caporali and Gould, {Gwyn W.} and George, {Sarah J.} and Igor Ulitsky and Sluimer, {Judith C.} and Julie Rodor and Baker, {Andrew H.}",

year = "2019",

month = aug,

day = "16",

doi = "10.1161/CIRCRESAHA.119.314876",

language = "English",

volume = "125",

pages = "535--551",

journal = "Circulation Research",

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Mahmoud, AD, Ballantyne, MD, Miscianinov, V, Pinel, K, Hung, J, Scanlon, JP, Iyinikkel, J, Kaczynski, J, Tavares, AS, Bradshaw, AC, Mills, NL, Newby, DE, Caporali, A, Gould, GW, George, SJ, Ulitsky, I, Sluimer, JC, Rodor, J & Baker, AH 2019, 'The Human-Specific and Smooth Muscle Cell-Enriched LncRNA SMILR Promotes Proliferation by Regulating Mitotic CENPF mRNA and Drives Cell-Cycle Progression Which Can Be Targeted to Limit Vascular Remodeling', Circulation Research, vol. 125, no. 5, pp. 535-551. https://doi.org/10.1161/CIRCRESAHA.119.314876

The Human-Specific and Smooth Muscle Cell-Enriched LncRNA SMILR Promotes Proliferation by Regulating Mitotic CENPF mRNA and Drives Cell-Cycle Progression Which Can Be Targeted to Limit Vascular Remodeling. / Mahmoud, Amira D.; Ballantyne, Margaret D.; Miscianinov, Vladislav; Pinel, Karine; Hung, John; Scanlon, Jessica P.; Iyinikkel, Jean; Kaczynski, Jakub; Tavares, Adriana S.; Bradshaw, Angela C.; Mills, Nicholas L.; Newby, David E.; Caporali, Andrea; Gould, Gwyn W.; George, Sarah J.; Ulitsky, Igor; Sluimer, Judith C.; Rodor, Julie; Baker, Andrew H.

In: Circulation Research, Vol. 125, No. 5, 16.08.2019, p. 535-551.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - The Human-Specific and Smooth Muscle Cell-Enriched LncRNA SMILR Promotes Proliferation by Regulating Mitotic CENPF mRNA and Drives Cell-Cycle Progression Which Can Be Targeted to Limit Vascular Remodeling

AU - Mahmoud, Amira D.

AU - Ballantyne, Margaret D.

AU - Miscianinov, Vladislav

AU - Pinel, Karine

AU - Hung, John

AU - Scanlon, Jessica P.

AU - Iyinikkel, Jean

AU - Kaczynski, Jakub

AU - Tavares, Adriana S.

AU - Bradshaw, Angela C.

AU - Mills, Nicholas L.

AU - Newby, David E.

AU - Caporali, Andrea

AU - Gould, Gwyn W.

AU - George, Sarah J.

AU - Ulitsky, Igor

AU - Sluimer, Judith C.

AU - Rodor, Julie

AU - Baker, Andrew H.

PY - 2019/8/16

Y1 - 2019/8/16

KW - blood vessels

KW - cell cycle

KW - growth factors

KW - interleukins

KW - muscle cells

KW - noncoding RNA

KW - saphenous vein

KW - LONG NONCODING RNA

KW - EXPRESSION

KW - MIGRATION

KW - STENTS

KW - DIFFERENTIATION

KW - PROGNOSIS

KW - NETWORKS

KW - BIOLOGY

U2 - 10.1161/CIRCRESAHA.119.314876

DO - 10.1161/CIRCRESAHA.119.314876

M3 - Article

VL - 125

SP - 535

EP - 551

JO - Circulation Research

JF - Circulation Research

SN - 0009-7330

IS - 5

ER -

Mahmoud AD, Ballantyne MD, Miscianinov V, Pinel K, Hung J, Scanlon JP et al. The Human-Specific and Smooth Muscle Cell-Enriched LncRNA SMILR Promotes Proliferation by Regulating Mitotic CENPF mRNA and Drives Cell-Cycle Progression Which Can Be Targeted to Limit Vascular Remodeling. Circulation Research. 2019 Aug 16;125(5):535-551. https://doi.org/10.1161/CIRCRESAHA.119.314876