The Human-Specific and Smooth Muscle Cell-Enriched LncRNA SMILR Promotes Proliferation by Regulating Mitotic CENPF mRNA and Drives Cell-Cycle Progression Which Can Be Targeted to Limit Vascular Remodeling

Amira D. Mahmoud, Margaret D. Ballantyne, Vladislav Miscianinov, Karine Pinel, John Hung, Jessica P. Scanlon, Jean Iyinikkel, Jakub Kaczynski, Adriana S. Tavares, Angela C. Bradshaw, Nicholas L. Mills, David E. Newby, Andrea Caporali, Gwyn W. Gould, Sarah J. George, Igor Ulitsky, Judith C. Sluimer, Julie Rodor, Andrew H. Baker*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)535-551
Number of pages17
JournalCirculation Research
Volume125
Issue number5
DOIs
Publication statusPublished - 16 Aug 2019

Keywords

  • blood vessels
  • cell cycle
  • growth factors
  • interleukins
  • muscle cells
  • noncoding RNA
  • saphenous vein
  • LONG NONCODING RNA
  • EXPRESSION
  • MIGRATION
  • STENTS
  • DIFFERENTIATION
  • PROGNOSIS
  • NETWORKS
  • BIOLOGY

Cite this

Mahmoud, A. D., Ballantyne, M. D., Miscianinov, V., Pinel, K., Hung, J., Scanlon, J. P., Iyinikkel, J., Kaczynski, J., Tavares, A. S., Bradshaw, A. C., Mills, N. L., Newby, D. E., Caporali, A., Gould, G. W., George, S. J., Ulitsky, I., Sluimer, J. C., Rodor, J., & Baker, A. H. (2019). The Human-Specific and Smooth Muscle Cell-Enriched LncRNA SMILR Promotes Proliferation by Regulating Mitotic CENPF mRNA and Drives Cell-Cycle Progression Which Can Be Targeted to Limit Vascular Remodeling. Circulation Research, 125(5), 535-551. https://doi.org/10.1161/CIRCRESAHA.119.314876