Low human and murine Mcl-1 expression leads to a pro-apoptotic plaque phenotype enriched in giant-cells

Margaux A. C. Fontaine, Marijke M. Westra, Ilze Bot, Han Jin, Aimee J. P. M. Franssen, Martine Bot, Saskia C. A. de Jager, Ivan Dzhagalov, You-Wen He, Bart J. M. van Vlijmen, Marion J. J. Gijbels, Chris P. Reutelingsperger, Theo J. C. van Berkel, Judith C. Sluimer, Lieve Temmerman*, Erik A. L. Biessen

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number14547
Number of pages11
JournalScientific Reports
Volume9
DOIs
Publication statusPublished - 10 Oct 2019

Keywords

  • ATHEROSCLEROTIC PLAQUES
  • MACROPHAGES
  • NEUTROPHILS
  • DEATH
  • BCL-2
  • INDUCTION
  • ARTERIES
  • PROTEIN

Cite this

Fontaine, M. A. C., Westra, M. M., Bot, I., Jin, H., Franssen, A. J. P. M., Bot, M., de Jager, S. C. A., Dzhagalov, I., He, Y-W., van Vlijmen, B. J. M., Gijbels, M. J. J., Reutelingsperger, C. P., van Berkel, T. J. C., Sluimer, J. C., Temmerman, L., & Biessen, E. A. L. (2019). Low human and murine Mcl-1 expression leads to a pro-apoptotic plaque phenotype enriched in giant-cells. Scientific Reports, 9, [14547]. https://doi.org/10.1038/s41598-019-51020-3