Low human and murine Mcl-1 expression leads to a pro-apoptotic plaque phenotype enriched in giant-cells

Margaux A. C. Fontaine, Marijke M. Westra, Ilze Bot, Han Jin, Aimee J. P. M. Franssen, Martine Bot, Saskia C. A. de Jager, Ivan Dzhagalov, You-Wen He, Bart J. M. van Vlijmen, Marion J. J. Gijbels, Chris P. Reutelingsperger, Theo J. C. van Berkel, Judith C. Sluimer, Lieve Temmerman*, Erik A. L. Biessen

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number14547
Number of pages11
JournalScientific Reports
Volume9
DOIs
Publication statusPublished - 10 Oct 2019

Keywords

  • ATHEROSCLEROTIC PLAQUES
  • MACROPHAGES
  • NEUTROPHILS
  • DEATH
  • BCL-2
  • INDUCTION
  • ARTERIES
  • PROTEIN

Cite this

Fontaine, Margaux A. C. ; Westra, Marijke M. ; Bot, Ilze ; Jin, Han ; Franssen, Aimee J. P. M. ; Bot, Martine ; de Jager, Saskia C. A. ; Dzhagalov, Ivan ; He, You-Wen ; van Vlijmen, Bart J. M. ; Gijbels, Marion J. J. ; Reutelingsperger, Chris P. ; van Berkel, Theo J. C. ; Sluimer, Judith C. ; Temmerman, Lieve ; Biessen, Erik A. L. / Low human and murine Mcl-1 expression leads to a pro-apoptotic plaque phenotype enriched in giant-cells. In: Scientific Reports. 2019 ; Vol. 9.
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title = "Low human and murine Mcl-1 expression leads to a pro-apoptotic plaque phenotype enriched in giant-cells",
keywords = "ATHEROSCLEROTIC PLAQUES, MACROPHAGES, NEUTROPHILS, DEATH, BCL-2, INDUCTION, ARTERIES, PROTEIN",
author = "Fontaine, {Margaux A. C.} and Westra, {Marijke M.} and Ilze Bot and Han Jin and Franssen, {Aimee J. P. M.} and Martine Bot and {de Jager}, {Saskia C. A.} and Ivan Dzhagalov and You-Wen He and {van Vlijmen}, {Bart J. M.} and Gijbels, {Marion J. J.} and Reutelingsperger, {Chris P.} and {van Berkel}, {Theo J. C.} and Sluimer, {Judith C.} and Lieve Temmerman and Biessen, {Erik A. L.}",
year = "2019",
month = "10",
day = "10",
doi = "10.1038/s41598-019-51020-3",
language = "English",
volume = "9",
journal = "Scientific Reports",
issn = "2045-2322",
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}

Low human and murine Mcl-1 expression leads to a pro-apoptotic plaque phenotype enriched in giant-cells. / Fontaine, Margaux A. C.; Westra, Marijke M.; Bot, Ilze; Jin, Han; Franssen, Aimee J. P. M.; Bot, Martine; de Jager, Saskia C. A.; Dzhagalov, Ivan; He, You-Wen; van Vlijmen, Bart J. M.; Gijbels, Marion J. J.; Reutelingsperger, Chris P.; van Berkel, Theo J. C.; Sluimer, Judith C.; Temmerman, Lieve; Biessen, Erik A. L.

In: Scientific Reports, Vol. 9, 14547, 10.10.2019.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Low human and murine Mcl-1 expression leads to a pro-apoptotic plaque phenotype enriched in giant-cells

AU - Fontaine, Margaux A. C.

AU - Westra, Marijke M.

AU - Bot, Ilze

AU - Jin, Han

AU - Franssen, Aimee J. P. M.

AU - Bot, Martine

AU - de Jager, Saskia C. A.

AU - Dzhagalov, Ivan

AU - He, You-Wen

AU - van Vlijmen, Bart J. M.

AU - Gijbels, Marion J. J.

AU - Reutelingsperger, Chris P.

AU - van Berkel, Theo J. C.

AU - Sluimer, Judith C.

AU - Temmerman, Lieve

AU - Biessen, Erik A. L.

PY - 2019/10/10

Y1 - 2019/10/10

KW - ATHEROSCLEROTIC PLAQUES

KW - MACROPHAGES

KW - NEUTROPHILS

KW - DEATH

KW - BCL-2

KW - INDUCTION

KW - ARTERIES

KW - PROTEIN

U2 - 10.1038/s41598-019-51020-3

DO - 10.1038/s41598-019-51020-3

M3 - Article

VL - 9

JO - Scientific Reports

JF - Scientific Reports

SN - 2045-2322

M1 - 14547

ER -