19952020

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2020

Multicentre study on the consistency of PD-L1 immunohistochemistry as predictive test for immunotherapy in non-small cell lung cancer

Butter, R., 't Hart, N. A., Hooijer, G. K. J., Monkhorst, K., Speel, E-J., Theunissen, P., Thunnissen, E., Von der Thüsen, J. H., Timens, W. & van de Vijver, M. J., Jul 2020, In : Journal of Clinical Pathology. 73, 7, p. 423-430 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Programmed death-ligand 1 expression influenced by tissue sample size. Scoring based on tissue microarrays' and cross-validation with resections, in patients with, stage I-III, non-small cell lung carcinoma of the European Thoracic Oncology Platform Lungscape cohort

Thunnissen, E., Kerr, K. M., Dafni, U., Bubendorf, L., Finn, S. P., Soltermann, A., Biernat, W., Cheney, R., Verbeken, E., Warth, A., Marchetti, A., Speel, E-J. M., Pokharel, S., Quinn, A. M., Monkhorst, K., Navarro, A., Madsen, L. B., Tsourti, Z., Geiger, T., Kammler, R. & 5 others, Peters, S., Stahel, R. A., European Thoracic Oncology Platform Lungscape Consortium, Dingemans, A-M. & Ruland, A. M., May 2020, In : Modern Pathology. 33, 5, p. 792-801 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Tumor control of cervical lymph node metastases of unknown primary origin: the impact of the radiotherapy target volume

Straetmans, J. M. J. A. A., Stuut, M., Wagemakers, S., Hoebers, F., Kaanders, J. H. A. M., Speel, E. J. M., Melchers, W. J. G., Slootweg, P., Kremer, B., Lacko, M. & Takes, R. P., Jun 2020, In : European Archives of Oto-Rhino-Laryngology. 277, 6, p. 1753-1761 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

2019

ALK immunohistochemistry positive, FISH negative NSCLC is infrequent, but associated with impaired survival following treatment with crizotinib

Thunnissen, E., Lissenberg-Witte, B., van den Heuvel, M. M., Monkhorst, K., Skov, B. G., Sorensen, J. B., Mellemgaard, A., Dingemans, A. M. C., Speel, E. J. M., de Langen, A. J., Hashemi, S. M. S., Bahce, I., van der Drift, M. A., Looijen-Salamon, M. G., Gosney, J., Postmus, P. E., Samii, S. M. S., Duplaquet, F., Weynand, B., Durando, X. & 15 others, Penault-Llorca, F., Finn, S., Grady, A. O., Oz, B., Akyurek, N., Buettner, R., Wolf, J., Bubendorf, L., Duin, S., Marondel, L., Heukamp, L. C., Timens, W., Schuuring, E. M. D., Pauwels, P. & Smit, E. F., Dec 2019, In : Lung Cancer. 138, p. 13-18 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

A retrospective cohort study of PD-L1 prevalence, molecular associations and clinical outcomes in patients with NSCLC: Results from the European Thoracic Oncology Platform (ETOP) Lungscape Project

Kerr, K. M., Thunnissen, E., Dafni, U., Finn, S. P., Bubendorf, L., Soltemiann, A., Verbeken, E., Biernat, W., Warth, A., Marchetti, A., Speel, E-J. M., Pokharel, S., Quinn, A. M., Monlchorst, K., Navarro, A., Madsen, L. B., Radonic, T., Wilson, J., De Luca, G., Gray, S. G. & 31 others, Cheney, R., Savic, S., Martorell, M., Muley, T., Baas, P., Meldgaard, P., Blackhall, F., Dingemans, A-M., Dziadziuszko, R., Vansteenkiste, J., Weder, W., Polydoropoulou, V., Geiger, T., Kammler, R., Peters, S., Stahel, R., Stahel, R. A., Rosell, R., Blackhall, F., Dafni, U., Molina, M. A., Bubendorf, L., Weder, W., Thunnissen, E., Peters, S., Finn, S., Hiltbrunner, A., Smit, E., Dingemans, A-M., Pokharel, S. & Lungscape Consortium, May 2019, In : Lung Cancer. 131, p. 95-103 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

DLL3 expression in large cell neuroendocrine carcinoma (LCNEC) and association with molecular subtypes and neuroendocrine profile

Hermans, B. C. M., Derks, J. L., Thunnissen, E., van Suylen, R. J., den Bakker, M. A., Groen, H. J. M., Smit, E. F., Damhuis, R. A., van den Broek, E. C., Ruland, A., Speel, E. J. M., Dingemans, A. M. C. & PALGA Grp, Dec 2019, In : Lung Cancer. 138, p. 102-108 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Integrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoids

Alcala, N., Leblay, N., Gabriel, A. A. G., Mangiante, L., Hervas, D., Giffon, T., Sertier, A. S., Ferrari, A., Derks, J., Ghantous, A., Delhomme, T. M., Chabrier, A., Cuenin, C., Abedi-Ardekani, B., Boland, A., Olaso, R., Meyer, H., Altmuller, J., Le Calvez-Kelm, F., Durand, G. & 50 others, Voegele, C., Boyault, S., Moonen, L., Lemaitre, N., Lorimier, P., Toffart, A. C., Soltermann, A., Clement, J. H., Saenger, J., Field, J. K., Brevet, M., Blanc-Fournier, C., Galateau-Salle, F., Le Stang, N., Russell, P. A., Wright, G., Sozzi, G., Pastorino, U., Lacomme, S., Vignaud, J. M., Hofman, M., Hofman, P., Brustugun, O. T., Lund-Iversen, M., de Montpreville, V. T., Muscarella, L. A., Graziano, P., Popper, H., Stojsic, J., Deleuze, J. F., Herceg, Z., Viari, A., Nuernberg, P., Pelosi, G., Dingemans, A. M. C., Milione, M., Roz, L., Brcic, L., Volante, M., Papotti, M. G., Caux, C., Sandoval, J., Hernandez-Vargas, H., Brambilla, E., Speel, E. J. M., Girard, N., Lantuejoul, S., McKay, J. D., Foll, M. & Fernandez-Cuesta, L., 20 Aug 2019, In : Nature Communications. 10, p. 1-21 21 p., 3407.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Is the sum of positive neuroendocrine immunohistochemical stains useful for diagnosis of large cell neuroendocrine carcinoma (LCNEC) on biopsy specimens?

Derks, J. L., Dingemans, A-M. C., van Suylen, R-J., den Bakker, M. A., Damhuis, R. A. M., van den Broek, E. C., Speel, E-J. & Thunnissen, E., Mar 2019, In : Histopathology. 74, 4, p. 555-566 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Large cell neuroendocrine carcinoma with a solitary brain metastasis and low Ki-67: a unique subtype

Hermans, B. C. M., Derks, J. L., Groen, H. J. M., Stigt, J. A., van Suylen, R. J., Hillen, L. M., van den Broek, E. C., Speel, E. J. M. & Dingemans, A-M. C., Dec 2019, In : Endocrine Connections . 8, 12, p. 1600-1606 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Multicenter Evaluation of the Fully Automated PCR-Based Idylla EGFR Mutation Assay on Forman-Fixed, Paraffin-Embedded Tissue of Human Lung Cancer

Evrard, S. M., Taranchon-Clermont, E., Rouquette, I., Murray, S., Dintner, S., Nam-Apostolopoulos, Y-C., Bellosillo, B., Varela-Rodriguez, M., Nadal, E., Wiedorn, K. H., Melchior, L., Andrew, E., Jones, M., Ridgway, J., Frykman, C., Lind, L., Rot, M., Kern, I., Speel, E. J. M., Roemen, G. M. J. M. & 3 others, Trincheri, N., Freiberger, S. N. & Rechsteiner, M., Nov 2019, In : Journal of Molecular Diagnostics. 21, 6, p. 1010-1024 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Prevalence and prognostic value of PD-L1 expression in molecular subtypes of metastatic large cell neuroendocrine carcinoma (LCNEC)

Hermans, B. C. M., Derks, J. L., Thunnissen, E., van Suylen, R. J., den Bakker, M. A., Groen, H. J. M., Smit, E. F., Damhuis, R. A., van den Broek, E. C., Stallinga, C. M., Roemen, G. M., Speel, E. J. M., Dingemans, A. -M. C. & PALGA Grp, Apr 2019, In : Lung Cancer. 130, p. 179-186 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Recommendations for the clinical interpretation and reporting of copy number gains using gene panel NGS analysis in routine diagnostics

Eijkelenboom, A., Tops, B. B. J., van den Berg, A., van den Brule, A. J. C., Dinjens, W. N. M., Dubbink, H. J., ter Elst, A., Geurts-Giele, W. R. R., Groenen, P. J. T. A., Groenendijk, F. H., Heideman, D. A. M., Huibers, M. M. H., Huijsmans, C. J. J., Jeuken, J. W. M., van Kempen, L. C., Korpershoek, E., Kroeze, L. I., de Leng, W. W. J., van Noesel, C. J. M., Speel, E-J. M. & 5 others, Vogel, M. J., van Wezel, T., Nederlof, P. M., Schuuring, E. & Ligtenberg, M. J. L., Jun 2019, In : Virchows Archiv. 474, 6, p. 673-680 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The Antiviral Agent Cidofovir Induces DNA Damage and Mitotic Catastrophe in HPV-Positive and -Negative Head and Neck Squamous Cell Carcinomas In Vitro

Verhees, F., Legemaate, D., Demers, I., Jacobs, R., Haakma, W. E., Rousch, M., Kremer, B. & Speel, E. J., 26 Jun 2019, In : Cancers. 11, 7, 15 p., 919.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Upregulation of AKR1C1 and AKR1C3 expression in OPSCC with integrated HPV16 and HPV-negative tumors is an indicator of poor prognosis

Huebbers, C. U., Verhees, F., Poluschkin, L., Olthof, N. C., Kolligs, J., Siefer, O. G., Henfling, M., Ramaekers, F. C. S., Preuss, S. F., Beutner, D., Seehawer, J., Drebber, U., Korkmaz, Y., Lam, W. L., Vucic, E. A., Kremer, B., Klussmann, J. P. & Speel, E-J. M., 15 May 2019, In : International Journal of Cancer. 144, 10, p. 2465-2477 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

2018

Computer-Based Intensity Measurement Assists Pathologists in Scoring Phosphatase and Tensin Homolog Immunohistochemistry - Clinical Associations in NSCLC Patients of the European Thoracic Oncology Platform Lungscape Cohort

Rulle, U., Tsourti, Z., Casanova, R., Deml, K-F., Verbeken, E., Thunnissen, E., Warth, A., Cheney, R., Sejda, A., Speel, E. J., Madsen, L. B., Nonaka, D., Navarro, A., Sansano, I., Marchetti, A., Finn, S. P., Monkhorst, K., Kerr, K. M., Haberecker, M., Wu, C. & 15 others, Zygoura, P., Kammler, R., Geiger, T., Gendreau, S., Schulze, K., Vrugt, B., Wild, P., Moch, H., Weder, W., Ciftlik, A. T., Dafni, U., Peters, S., Bubendorf, L., Stahel, R. A. & Soltermann, A., 1 Dec 2018, In : Journal of Thoracic Oncology. 13, 12, p. 1851-1863 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Detection of Merkel Cell Polyomavirus in Seborrheic Keratosis

Hillen, L. M., Rennspiess, D., Speel, E-J., Haugg, A. M., Winnepenninckx, V. & Zur Hausen, A., 9 Jan 2018, In : Frontiers in microbiology. 8, 8 p., 2648.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Evaluation of NGS and RT-PCR Methods for ALK Rearrangement in European NSCLC Patients: Results from the European Thoracic Oncology Platform Lungscape Project

Letovanec, I., Finn, S., Zygoura, P., Smyth, P., Soltermann, A., Bubendorf, L., Speel, E-J., Marchetti, A., Nonaka, D., Monkhorst, K., Hager, H., Martorell, M., Sejda, A., Cheney, R., Hernandez-Losa, J., Verbeken, E., Weder, W., Savic, S., Di Lorito, A., Navarro, A. & 20 others, Felip, E., Warth, A., Baas, P., Meldgaard, P., Blackhall, F., Dingemans, A-M., Dienemann, H., Dziadziuszko, R., Vansteenkiste, J., O'Brien, C., Geiger, T., Sherlock, J., Schageman, J., Dafni, U., Kammler, R., Kerr, K., Thunnissen, E., Stahel, R., Peters, S. & European Thoracic Oncology, 1 Mar 2018, In : Journal of Thoracic Oncology. 13, 3, p. 413-425 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Methylation of L1RE1, RARB, and RASSF1 function as possible biomarkers for the differential diagnosis of lung cancer

Walter, R. F. H., Rozynek, P., Casjens, S., Werner, R., Mairinger, F. D., Speel, E. J. M., Zur Hausen, A., Meier, S., Wohlschlaeger, J., Theegarten, D., Behrens, T., Schmid, K. W., Bruning, T. & Johnen, G., 31 May 2018, In : PLOS ONE. 13, 5, p. 1 17 p., e0195716.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Molecular Subtypes of Pulmonary Large-cell Neuroendocrine Carcinoma Predict Chemotherapy Treatment Outcome

Derks, J. L., Leblay, N., Thunnissen, E., Van Suylen, R. J., den Bakker, M., Groen, H. J. M., Smit, E. F., Damhuis, R., van den Broek, E. C., Charbrier, A., Foll, M., McKay, J. D., Fernandez-Cuesta, L., Speel, E-J. M., Dingemans, A-M. C. & PALGA Grp, 1 Jan 2018, In : Clinical Cancer Research. 24, 1, p. 33-42 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Neuroendocrine Key Regulator Gene Expression in Merkel Cell Carcinoma

Chteinberg, E., Sauer, C. M., Rennspiess, D., Beumers, L., Schiffelers, L., Eben, J., Haugg, A., Winnepenninckx, V., Kurz, A. K., Speel, E-J., Zenke, M. & zur Hausen, A., Dec 2018, In : Neoplasia (Online). 20, 12, p. 1227-1235 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Oncogenic Viruses in Skull Base Chordomas

Yakkioui, Y., Speel, E-J. M., Van Overbeeke, J. J., Boderie, M. J. M., Pujari, S., Hausen, A. Z., Wolffs, P. F. G. & Temel, Y., 1 Apr 2018, In : World Neurosurgery. 112, p. E7-E13 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Phosphatidylinositol 3-kinase p110δ expression in Merkel cell carcinoma

Chteinberg, E., Rennspiess, D., Sambo, R., Tauchmann, S., Kelleners-Smeets, N. W. J., Winnepenninckx, V., Speel, E., Kurz, A. K., Zenke, M. & zur Hausen, A., 2018, In : Oncotarget. 9, 51, p. 29565-29573

Research output: Contribution to journalArticleAcademicpeer-review

Prevalence and clinical association of gene mutations through multiplex mutation testing in patients with NSCLC: results from the ETOP Lungscape Project

Kerr, K. M., Dafni, U., Schulze, K., Thunnissen, E., Bubendorf, L., Hager, H., Finn, S., Biernat, W., Vliegen, L., Losa, J. H., Marchetti, A., Cheney, R., Warth, A., Speel, E. -J., Blackhall, F., Monkhorst, K., Lewintre, E. J., Tischler, V., Clark, C., Bertran-Alamillo, J. & 23 others, Meldgaard, P., Gately, K., Wrona, A., Vandenberghe, P., Felip, E., De Luca, G., Savic, S., Muley, T., Smit, E. F., Dingemans, A. -M. C., Priest, L., Baas, P., Camps, C., Weder, W., Polydoropoulou, V., Geiger, T. R., Kammler, R., Sumiyoshi, T., Molina, M. A., Shames, D. S., Stahel, R. A., Peters, S. & Etop Lungscape Consortium, 1 Jan 2018, In : Annals of Oncology. 29, 1, p. 200-208 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

The IGF pathway is activated in insulinomas but downregulated in metastatic disease

Henfling, M. E. R., Perren, A. A., Schmitt, A. M., Saddig, C. M., Starke, A. A., Riedl, R. G., Versleijen-Jonkers, Y. M. H., Sprij-Mooij, D. M., Ramaekers, F. C. S., Hofland, L. J. & Speel, E-J. M., Dec 2018, In : Endocrine-Related Cancer. 25, 12, p. 1005-1018 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

2017

Chemotherapy for pulmonary large cell neuroendocrine carcinomas: does the regimen matter?

Derks, J. L., van Suylen, R. J., Thunnissen, E., den Bakker, M. A., Groen, H. J., Smit, E. F., Damhuis, R. A., van den Broek, E. C., Speel, E-J. M., Dingemans, A-M. C. & PALGA Grp, Jun 2017, In : European Respiratory Journal. 49, 6, 9 p., 1601838.

Research output: Contribution to journalArticleAcademicpeer-review

Chromosome instability in tumor resection margins of primary OSCC is a predictor of local recurrence

Pierssens, D. D. C. G., Borgemeester, M. C., van der Heijden, S. J. H., Peutz-Kootstra, C. J., Ruland, A. M., Haesevoets, A. M., Kessler, P. A. W. H., Kremer, B. & Speel, E-J. M., Mar 2017, In : Oral Oncology. 66, p. 14-21 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Dichotomous ALK-IHC Is a Better Predictor for ALK Inhibition Outcome than Traditional ALK-FISH in Advanced Non-Small Cell Lung Cancer

van der Wekken, A. J., Pelgrim, R., 't Hart, N., Werner, N., Mastik, M. F., Hendriks, L., van der Heijden, E. H. F. M., Looijen-Salamon, M., de langen, A. J., Staal-van den Brekel, J., Riemersma, S., van den Borne, B. E., Speel, E. J. M., Dingemans, A-M. C., Hiltermann, T. J. N., van den Berg, A., Timens, W., Schuuring, E. & Groen, H. J. M., 1 Aug 2017, In : Clinical Cancer Research. 23, 15, p. 4251-4258 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Female urothelial cell carcinoma in a failed kidney graft of a male recipient

de Jongh, H. J. J., van Duijnhoven, E. M., Ruland, A., Hamid, M. M. A. A., Speel, E. J. M. & van de Beek, K., Oct 2017, In : Netherlands Journal of Medicine. 75, 8, p. 354-356 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

Limited additive value of the Ki-67 proliferative index on patient survival in World Health Organization-classified pulmonary carcinoids

Swarts, D. R. A., Rudelius, M., Claessen, S. M. H., Cleutjens, J. P., Seidl, S., Volante, M., Ramaekers, F. C. S. & Speel, E. J. M., Feb 2017, In : Histopathology. 70, 3, p. 412-422 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

PET imaging of zirconium-89 labelled cetuximab: A phase I trial in patients with head and neck and lung cancer

van Loon, J., Even, A. J. G., Aerts, H. J. W. L., Ollers, M., Hoebers, F., van Elmpt, W., Dubois, L., Dingemans, A-M. C., Lalisang, R. I., Kempers, P., Brans, B., Winnepenninckx, V., Speel, E-J., Thunnissen, E., Smits, K. M., Boellaard, R., Vugts, D. J., De Ruysscher, D. & Lambin, P., Feb 2017, In : Radiotherapy and Oncology. 122, 2, p. 267-273 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Postzygotic mosaicism in basal cell naevus syndrome

Reinders, M. G. H. C., Boersma, H. J., Leter, E. M., Vreeburg, M., Paulussen, A. D. C., Arits, A. H. M. M., Roemen, G. M. J. M., Speel, E. J. M., Steijlen, P. M., van Geel, M. & Mosterd, K., Jul 2017, In : British Journal of Dermatology. 177, 1, p. 249-252 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Prevalence and clinical association of MET gene overexpression and amplification in patients with NSCLC: Results from the European Thoracic Oncology Platform (ETOP) Lungscape project

Bubendorf, L., Dafni, U., Schobel, M., Finn, S. P., Tischler, V., Sejda, A., Marchetti, A., Thunnissen, E., Verbeken, E. K., Warth, A., Sansano, I., Cheney, R., Speel, E. J. M., Nonaka, D., Monkhorst, K., Hager, H., Martorell, M., Savic, S., Kerr, K. M., Tan, Q. & 9 others, Tsourti, Z., Geiger, T. R., Kammler, R., Schulze, K., Das-Gupta, A., Shames, D., Peters, S., Stahel, R. A. & Lungscape Consortium, Sep 2017, In : Lung Cancer. 111, p. 143-149 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Prevalence of high-risk human papillomavirus infection and cancer gene mutations in nonmalignant tonsils

Ilmarinen, T., Munne, P., Hagstrom, J., Haglund, C., Auvinen, E., Virtanen, E. I., Haesevoets, A., Speel, E. J. M. & Aaltonen, L-M., Oct 2017, In : Oral Oncology. 73, p. 77-82 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

2016

A Population-Based Analysis of Application of WHO Nomenclature in Pathology Reports of Pulmonary Neuroendocrine Tumors

Derks, J. L., van Suylen, R. J., Thunnissen, E., den Bakker, M. A., Smit, E. F., Groen, H. J. M., Speel, E. J. M. & Dingemans, A-M. C., Apr 2016, In : Journal of Thoracic Oncology. 11, 4, p. 593-602 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
1 Citation (Scopus)

Clinical features of large cell neuroendocrine carcinoma: a population-based overview

Derks, J. L., Hendriks, L. E., Buikhuisen, W. A., Groen, H. J. M., Thunnissen, E., van Suylen, R-J., Houben, R., Damhuis, R. A., Speel, E. J. M. & Dingemans, A-M. C., Feb 2016, In : European Respiratory Journal. 47, 2, p. 615-624

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Development and validation of a staging system for HPV-related oropharyngeal cancer by the International Collaboration on Oropharyngeal cancer Network for Staging (ICON-S): a multicentre cohort study

O'Sullivan, B., Huang, S. H., Su, J., Garden, A. S., Sturgis, E. M., Dahlstrom, K., Lee, N., Riaz, N., Pei, X., Koyfman, S. A., Adelstein, D., Burkey, B. B., Friborg, J., Kristensen, C. A., Gothelf, A. B., Hoebers, F., Kremer, B., Speel, E-J., Bowles, D. W., Raben, D. & 3 others, Karam, S. D., Yu, E. & Xu, W., Apr 2016, In : Lancet oncology. 17, 4, p. 440-451

Research output: Contribution to journalArticleAcademicpeer-review

24 Citations (Scopus)

Frequent detection of human polyomavirus 6 in keratoacanthomas

Beckervordersandforth, J., Pujari, S., Rennspiess, D., Speel, E. J. M., Winnepenninckx, V., Diaz, C., Weyers, W., Haugg, A. M., Kurz, A. K. & zur Hausen, A., 7 Jul 2016, In : Diagnostic Pathology. 11, 58.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
4 Citations (Scopus)

Identification of CD90 as Putative Cancer Stem Cell Marker and Therapeutic Target in Insulinomas

Buishand, F. O., Arkesteijn, G. J. A., Feenstra, L. R., Oorsprong, C. W. D., Mestemaker, M., Starke, A., Speel, E-J. M., Kirpensteijn, J. & Mol, J. A., 1 Jun 2016, In : Stem Cells and Development. 25, 11, p. 826-835

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Refining the Diagnosis of Congenital Nephrotic Syndrome on Long-term Stored Tissue: c.1097G>A (p.(Arg366His)) WT1 Mutation Causing Denys Drash Syndrome

Hillen, L. M., Kamsteeg, E. J., Schoots, J., Tiebosch, A. T., Speel, E. J., Roemen, G. M., Peutz - Kootstra, C. & Stumpel, C. T. R. M., 3 Mar 2016, In : Fetal and Pediatric Pathology. 35, 2, p. 112-119

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2015

Characterization of the 12q Amplicons in Lipomatous Soft Tissue Tumors by Multiplex Ligation-dependent Probe Amplification-based Copy Number Analysis

Creytens, D., Van Gorp, J., Speel, E-J. & Ferdinande, L., Apr 2015, In : Anticancer Research. 35, 4, p. 1835-1842

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Detection of HPV-associated oropharyngeal tumours in a 16-year cohort: more than meets the eye

Melchers, L. J., Mastik, M. F., Cameron, B. S., van Dijk, B. A. C., de Bock, G. H., van der Laan, B. F. A. M., van der Vegt, B., Speel, E. J. M., Roodenburg, J. L. N., Witjes, M. J. H. & Schuuring, E., 14 Apr 2015, In : British Journal of Cancer. 112, 8, p. 1349-1357

Research output: Contribution to journalArticleAcademicpeer-review

11 Citations (Scopus)

Detection of Human Polyomavirus 7 in Human Thymic Epithelial Tumors

Rennspiess, D., Pujari, S., Keijzers, M., Abdul-Hamid, M. A., Hochstenbag, M., Dingemans, A-M., Kurz, A. K., Speel, E-J., Haugg, A., Pastrana, D. V., Buck, C. B., De Baets, M. H. & zur Hausen, A., Feb 2015, In : Journal of Thoracic Oncology. 10, 2, p. 360-366

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Scopus)
2 Citations (Scopus)

Different prognostic models for different patient populations: validation of a new prognostic model for patients with oropharyngeal cancer in Western Europe

Rietbergen, M. M., Witte, B. I., Velazquez, E. R., Snijders, P. J. F., Bloemena, E., Speel, E. J., Brakenhoff, R. H., Kremer, B., Lambin, P. & Leemans, C. R., 26 May 2015, In : British Journal of Cancer. 112, 11, p. 1733-1736

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)

Gene expression profiling of pulmonary neuroendocrine neoplasms: a comprehensive overview

Swarts, D., Ramaekers, F. & Speel, E., 2015, In : Cancer Treatment Communications. 4, p. 148-160

Research output: Contribution to journalArticleAcademicpeer-review

Germ-line variants identified by next generation sequencing in a panel of estrogen and cancer associated genes correlate with poor clinical outcome in Lynch syndrome patients

Jori, B., Kamps, R., Xanthoulea, S., Delvoux, B., Blok, M. J., Van de Vijver, K. K., de Koning, B., Oei, F. T., Tops, C. M., Speel, E. J. M., Kruitwagen, R. F., Gomez-Garcia, E. B. & Romano, A., 1 Dec 2015, In : Oncotarget. 6, 38, p. 41108-41122

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Identification of MicroRNAs Differentially Expressed in Lung Carcinoid Subtypes and Progression

Rapa, I., Votta, A., Felice, B., Righi, L., Giorcelli, J., Scarpa, A., Speel, E-J. M., Scagliotti, G. V., Papotti, M. & Volante, M., 2015, In : Neuroendocrinology. 101, 3, p. 246-255

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Management of neck metastases of unknown primary origin united in two European centers

Straetmans, J., Vent, J., Lacko, M., Speel, E-J., Huebbers, C., Semrau, R., Hoebers, F., Mujagic, Z., Klussmann, J-P., Preuss, S. F. & Kremer, B., Jan 2015, In : European Archives of Oto-Rhino-Laryngology. 272, 1, p. 195-205

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Methylation status of HPV16 E2-binding sites classifies subtypes of HPV-associated oropharyngeal cancers

Reuschenbach, M., Huebbers, C. U., Prigge, E-S., Bermejo, J. L., Kalteis, M. S., Preuss, S. F., Seuthe, I. M. C., Kolligs, J., Speel, E-J. M., Olthof, N., Kremer, B., Wagner, S., Klussmann, J. P., Vinokurova, S. & Doeberitz, M. V. K., 15 Jun 2015, In : Cancer. 121, 12, p. 1966-1976

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)

MK3 Modulation Affects BMI1-Dependent and Independent Cell Cycle Check-Points

Prickaerts, P., Niessen, H. E. C., Dahlmans, V. E. H., Spaapen, F., Salvaing, J., Vanhove, J., Geijselaers, C., Bartels, S. J. J., Partouns, I., Neumann, D., Speel, E-J., Takihara, Y., Wouters, B. G. & Voncken, J. W., 8 Apr 2015, In : PLOS ONE. 10, 4, e0118840.

Research output: Contribution to journalArticleAcademicpeer-review