PD-L1 Expression and a High Tumor Infiltrate of CD8+Lymphocytes Predict Outcome in Patients with Oropharyngeal Squamous Cells Carcinoma

Nora Wuerdemann*, Sibel E. Gultekin, Katharina Puetz, Claus Wittekindt, Christian U. Huebbers, Shachi J. Sharma, Hans Eckel, Anna B. Schubotz, Stefan Gattenloehner, Reinhard Buettner, Ernst-Jan Speel, Jens P. Klussmann, Steffen Wagner, Alexander Quaas

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number5228
Number of pages16
JournalInternational journal of molecular sciences
Volume21
Issue number15
DOIs
Publication statusPublished - Aug 2020

Keywords

  • oropharyngeal squamous cell carcinoma
  • human papillomavirus
  • programmed cell death 1 ligand 1
  • CD8-positive T-lymphocytes
  • MHC I
  • macrophages
  • tumor micro-environment
  • prognosis
  • HLA CLASS-I
  • HPV-ASSOCIATED HEAD
  • MHC CLASS-I
  • HUMAN-PAPILLOMAVIRUS
  • PROGNOSTIC BIOMARKER
  • T-CELLS
  • DOWN-REGULATION
  • NECK
  • ASSOCIATION
  • PROTEIN

Cite this

Wuerdemann, N., Gultekin, S. E., Puetz, K., Wittekindt, C., Huebbers, C. U., Sharma, S. J., Eckel, H., Schubotz, A. B., Gattenloehner, S., Buettner, R., Speel, E-J., Klussmann, J. P., Wagner, S., & Quaas, A. (2020). PD-L1 Expression and a High Tumor Infiltrate of CD8+Lymphocytes Predict Outcome in Patients with Oropharyngeal Squamous Cells Carcinoma. International journal of molecular sciences, 21(15), [5228]. https://doi.org/10.3390/ijms21155228