19952020

Research output per year

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Research Output

2020

Multicentre study on the consistency of PD-L1 immunohistochemistry as predictive test for immunotherapy in non-small cell lung cancer

Butter, R., 't Hart, N. A., Hooijer, G. K. J., Monkhorst, K., Speel, E-J., Theunissen, P., Thunnissen, E., Von der Thüsen, J. H., Timens, W. & van de Vijver, M. J., Jul 2020, In : Journal of Clinical Pathology. 73, 7, p. 423-430 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Organoid Models of Neuroendocrine Cell Growth and Tumorigenesis

Dayton, T., Den Hartigh, L. A., Levy, S., van den Berg, J. B., Kok, N., Buikhuisen, W., Hartemink, K., Speel, E. J., Valk, G. D., Tesselaar, M., Vriens, M. R. & Clevers, H., Mar 2020, In : Neuroendocrinology. 110, p. 24-24 1 p.

Research output: Contribution to journalConference Abstract/Poster in journalAcademic

Programmed death-ligand 1 expression influenced by tissue sample size. Scoring based on tissue microarrays' and cross-validation with resections, in patients with, stage I-III, non-small cell lung carcinoma of the European Thoracic Oncology Platform Lungscape cohort

Thunnissen, E., Kerr, K. M., Dafni, U., Bubendorf, L., Finn, S. P., Soltermann, A., Biernat, W., Cheney, R., Verbeken, E., Warth, A., Marchetti, A., Speel, E-J. M., Pokharel, S., Quinn, A. M., Monkhorst, K., Navarro, A., Madsen, L. B., Tsourti, Z., Geiger, T., Kammler, R. & 5 others, Peters, S., Stahel, R. A., European Thoracic Oncology Platform Lungscape Consortium, Dingemans, A-M. & Ruland, A. M., May 2020, In : Modern Pathology. 33, 5, p. 792-801 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Tumor control of cervical lymph node metastases of unknown primary origin: the impact of the radiotherapy target volume

Straetmans, J. M. J. A. A., Stuut, M., Wagemakers, S., Hoebers, F., Kaanders, J. H. A. M., Speel, E. J. M., Melchers, W. J. G., Slootweg, P., Kremer, B., Lacko, M. & Takes, R. P., Jun 2020, In : European Archives of Oto-Rhino-Laryngology. 277, 6, p. 1753-1761 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Unique Metastatic Patterns in Neuroendocrine Neoplasms of Different Primary Origin

Hermans, B., Derks, J., Willems, A., Bilochvostenko, M., Bayazit, S., Speel, E. J., Dercksen, W., de Vos-Geelen, J. & Dingemans, A. M., Mar 2020, In : Neuroendocrinology. 110, p. 81-81 1 p.

Research output: Contribution to journalConference Abstract/Poster in journalAcademic

2019

ALK immunohistochemistry positive, FISH negative NSCLC is infrequent, but associated with impaired survival following treatment with crizotinib

Thunnissen, E., Lissenberg-Witte, B., van den Heuvel, M. M., Monkhorst, K., Skov, B. G., Sorensen, J. B., Mellemgaard, A., Dingemans, A. M. C., Speel, E. J. M., de Langen, A. J., Hashemi, S. M. S., Bahce, I., van der Drift, M. A., Looijen-Salamon, M. G., Gosney, J., Postmus, P. E., Samii, S. M. S., Duplaquet, F., Weynand, B., Durando, X. & 15 others, Penault-Llorca, F., Finn, S., Grady, A. O., Oz, B., Akyurek, N., Buettner, R., Wolf, J., Bubendorf, L., Duin, S., Marondel, L., Heukamp, L. C., Timens, W., Schuuring, E. M. D., Pauwels, P. & Smit, E. F., Dec 2019, In : Lung Cancer. 138, p. 13-18 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

A retrospective cohort study of PD-L1 prevalence, molecular associations and clinical outcomes in patients with NSCLC: Results from the European Thoracic Oncology Platform (ETOP) Lungscape Project

Kerr, K. M., Thunnissen, E., Dafni, U., Finn, S. P., Bubendorf, L., Soltemiann, A., Verbeken, E., Biernat, W., Warth, A., Marchetti, A., Speel, E-J. M., Pokharel, S., Quinn, A. M., Monlchorst, K., Navarro, A., Madsen, L. B., Radonic, T., Wilson, J., De Luca, G., Gray, S. G. & 31 others, Cheney, R., Savic, S., Martorell, M., Muley, T., Baas, P., Meldgaard, P., Blackhall, F., Dingemans, A-M., Dziadziuszko, R., Vansteenkiste, J., Weder, W., Polydoropoulou, V., Geiger, T., Kammler, R., Peters, S., Stahel, R., Stahel, R. A., Rosell, R., Blackhall, F., Dafni, U., Molina, M. A., Bubendorf, L., Weder, W., Thunnissen, E., Peters, S., Finn, S., Hiltbrunner, A., Smit, E., Dingemans, A-M., Pokharel, S. & Lungscape Consortium, May 2019, In : Lung Cancer. 131, p. 95-103 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

DLL3 expression in large cell neuroendocrine carcinoma (LCNEC) and association with molecular subtypes and neuroendocrine profile

Hermans, B. C. M., Derks, J. L., Thunnissen, E., van Suylen, R. J., den Bakker, M. A., Groen, H. J. M., Smit, E. F., Damhuis, R. A., van den Broek, E. C., Ruland, A., Speel, E. J. M., Dingemans, A. M. C. & PALGA Grp, Dec 2019, In : Lung Cancer. 138, p. 102-108 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Integrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoids

Alcala, N., Leblay, N., Gabriel, A. A. G., Mangiante, L., Hervas, D., Giffon, T., Sertier, A. S., Ferrari, A., Derks, J., Ghantous, A., Delhomme, T. M., Chabrier, A., Cuenin, C., Abedi-Ardekani, B., Boland, A., Olaso, R., Meyer, H., Altmuller, J., Le Calvez-Kelm, F., Durand, G. & 50 others, Voegele, C., Boyault, S., Moonen, L., Lemaitre, N., Lorimier, P., Toffart, A. C., Soltermann, A., Clement, J. H., Saenger, J., Field, J. K., Brevet, M., Blanc-Fournier, C., Galateau-Salle, F., Le Stang, N., Russell, P. A., Wright, G., Sozzi, G., Pastorino, U., Lacomme, S., Vignaud, J. M., Hofman, M., Hofman, P., Brustugun, O. T., Lund-Iversen, M., de Montpreville, V. T., Muscarella, L. A., Graziano, P., Popper, H., Stojsic, J., Deleuze, J. F., Herceg, Z., Viari, A., Nuernberg, P., Pelosi, G., Dingemans, A. M. C., Milione, M., Roz, L., Brcic, L., Volante, M., Papotti, M. G., Caux, C., Sandoval, J., Hernandez-Vargas, H., Brambilla, E., Speel, E. J. M., Girard, N., Lantuejoul, S., McKay, J. D., Foll, M. & Fernandez-Cuesta, L., 20 Aug 2019, In : Nature Communications. 10, p. 1-21 21 p., 3407.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Is the sum of positive neuroendocrine immunohistochemical stains useful for diagnosis of large cell neuroendocrine carcinoma (LCNEC) on biopsy specimens?

Derks, J. L., Dingemans, A-M. C., van Suylen, R-J., den Bakker, M. A., Damhuis, R. A. M., van den Broek, E. C., Speel, E-J. & Thunnissen, E., Mar 2019, In : Histopathology. 74, 4, p. 555-566 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Large cell neuroendocrine carcinoma with a solitary brain metastasis and low Ki-67: a unique subtype

Hermans, B. C. M., Derks, J. L., Groen, H. J. M., Stigt, J. A., van Suylen, R. J., Hillen, L. M., van den Broek, E. C., Speel, E. J. M. & Dingemans, A-M. C., Dec 2019, In : Endocrine Connections . 8, 12, p. 1600-1606 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Multicenter Evaluation of the Fully Automated PCR-Based Idylla EGFR Mutation Assay on Forman-Fixed, Paraffin-Embedded Tissue of Human Lung Cancer

Evrard, S. M., Taranchon-Clermont, E., Rouquette, I., Murray, S., Dintner, S., Nam-Apostolopoulos, Y-C., Bellosillo, B., Varela-Rodriguez, M., Nadal, E., Wiedorn, K. H., Melchior, L., Andrew, E., Jones, M., Ridgway, J., Frykman, C., Lind, L., Rot, M., Kern, I., Speel, E. J. M., Roemen, G. M. J. M. & 3 others, Trincheri, N., Freiberger, S. N. & Rechsteiner, M., Nov 2019, In : Journal of Molecular Diagnostics. 21, 6, p. 1010-1024 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Orthopedia Homeobox (OTP) in Pulmonary Neuroendocrine Tumors: The Diagnostic Value and Possible Molecular Interactions

Moonen, L., Derks, J., Dingemans, A-M. & Speel, E-J., Oct 2019, In : Cancers. 11, 10, 13 p., 1508.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Prevalence and prognostic value of PD-L1 expression in molecular subtypes of metastatic large cell neuroendocrine carcinoma (LCNEC)

Hermans, B. C. M., Derks, J. L., Thunnissen, E., van Suylen, R. J., den Bakker, M. A., Groen, H. J. M., Smit, E. F., Damhuis, R. A., van den Broek, E. C., Stallinga, C. M., Roemen, G. M., Speel, E. J. M., Dingemans, A. -M. C. & PALGA Grp, Apr 2019, In : Lung Cancer. 130, p. 179-186 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Recommendations for the clinical interpretation and reporting of copy number gains using gene panel NGS analysis in routine diagnostics

Eijkelenboom, A., Tops, B. B. J., van den Berg, A., van den Brule, A. J. C., Dinjens, W. N. M., Dubbink, H. J., ter Elst, A., Geurts-Giele, W. R. R., Groenen, P. J. T. A., Groenendijk, F. H., Heideman, D. A. M., Huibers, M. M. H., Huijsmans, C. J. J., Jeuken, J. W. M., van Kempen, L. C., Korpershoek, E., Kroeze, L. I., de Leng, W. W. J., van Noesel, C. J. M., Speel, E-J. M. & 5 others, Vogel, M. J., van Wezel, T., Nederlof, P. M., Schuuring, E. & Ligtenberg, M. J. L., Jun 2019, In : Virchows Archiv. 474, 6, p. 673-680 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The Antiviral Agent Cidofovir Induces DNA Damage and Mitotic Catastrophe in HPV-Positive and -Negative Head and Neck Squamous Cell Carcinomas In Vitro

Verhees, F., Legemaate, D., Demers, I., Jacobs, R., Haakma, W. E., Rousch, M., Kremer, B. & Speel, E. J., 26 Jun 2019, In : Cancers. 11, 7, 15 p., 919.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Upregulation of AKR1C1 and AKR1C3 expression in OPSCC with integrated HPV16 and HPV-negative tumors is an indicator of poor prognosis

Huebbers, C. U., Verhees, F., Poluschkin, L., Olthof, N. C., Kolligs, J., Siefer, O. G., Henfling, M., Ramaekers, F. C. S., Preuss, S. F., Beutner, D., Seehawer, J., Drebber, U., Korkmaz, Y., Lam, W. L., Vucic, E. A., Kremer, B., Klussmann, J. P. & Speel, E-J. M., 15 May 2019, In : International Journal of Cancer. 144, 10, p. 2465-2477 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

2018

Computer-Based Intensity Measurement Assists Pathologists in Scoring Phosphatase and Tensin Homolog Immunohistochemistry - Clinical Associations in NSCLC Patients of the European Thoracic Oncology Platform Lungscape Cohort

Rulle, U., Tsourti, Z., Casanova, R., Deml, K-F., Verbeken, E., Thunnissen, E., Warth, A., Cheney, R., Sejda, A., Speel, E. J., Madsen, L. B., Nonaka, D., Navarro, A., Sansano, I., Marchetti, A., Finn, S. P., Monkhorst, K., Kerr, K. M., Haberecker, M., Wu, C. & 15 others, Zygoura, P., Kammler, R., Geiger, T., Gendreau, S., Schulze, K., Vrugt, B., Wild, P., Moch, H., Weder, W., Ciftlik, A. T., Dafni, U., Peters, S., Bubendorf, L., Stahel, R. A. & Soltermann, A., 1 Dec 2018, In : Journal of Thoracic Oncology. 13, 12, p. 1851-1863 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Detection of Merkel Cell Polyomavirus in Seborrheic Keratosis

Hillen, L. M., Rennspiess, D., Speel, E-J., Haugg, A. M., Winnepenninckx, V. & Zur Hausen, A., 9 Jan 2018, In : Frontiers in microbiology. 8, 8 p., 2648.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Evaluation of NGS and RT-PCR Methods for ALK Rearrangement in European NSCLC Patients: Results from the European Thoracic Oncology Platform Lungscape Project

Letovanec, I., Finn, S., Zygoura, P., Smyth, P., Soltermann, A., Bubendorf, L., Speel, E-J., Marchetti, A., Nonaka, D., Monkhorst, K., Hager, H., Martorell, M., Sejda, A., Cheney, R., Hernandez-Losa, J., Verbeken, E., Weder, W., Savic, S., Di Lorito, A., Navarro, A. & 20 others, Felip, E., Warth, A., Baas, P., Meldgaard, P., Blackhall, F., Dingemans, A-M., Dienemann, H., Dziadziuszko, R., Vansteenkiste, J., O'Brien, C., Geiger, T., Sherlock, J., Schageman, J., Dafni, U., Kammler, R., Kerr, K., Thunnissen, E., Stahel, R., Peters, S. & European Thoracic Oncology, 1 Mar 2018, In : Journal of Thoracic Oncology. 13, 3, p. 413-425 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Methylation of L1RE1, RARB, and RASSF1 function as possible biomarkers for the differential diagnosis of lung cancer

Walter, R. F. H., Rozynek, P., Casjens, S., Werner, R., Mairinger, F. D., Speel, E. J. M., Zur Hausen, A., Meier, S., Wohlschlaeger, J., Theegarten, D., Behrens, T., Schmid, K. W., Bruning, T. & Johnen, G., 31 May 2018, In : PLOS ONE. 13, 5, p. 1 17 p., e0195716.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Molecular Subtypes of Pulmonary Large-cell Neuroendocrine Carcinoma Predict Chemotherapy Treatment Outcome

Derks, J. L., Leblay, N., Thunnissen, E., Van Suylen, R. J., den Bakker, M., Groen, H. J. M., Smit, E. F., Damhuis, R., van den Broek, E. C., Charbrier, A., Foll, M., McKay, J. D., Fernandez-Cuesta, L., Speel, E-J. M., Dingemans, A-M. C. & PALGA Grp, 1 Jan 2018, In : Clinical Cancer Research. 24, 1, p. 33-42 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Neuroendocrine Key Regulator Gene Expression in Merkel Cell Carcinoma

Chteinberg, E., Sauer, C. M., Rennspiess, D., Beumers, L., Schiffelers, L., Eben, J., Haugg, A., Winnepenninckx, V., Kurz, A. K., Speel, E-J., Zenke, M. & zur Hausen, A., Dec 2018, In : Neoplasia (Online). 20, 12, p. 1227-1235 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

New Insights into the Molecular Characteristics of Pulmonary Carcinoids and Large Cell Neuroendocrine Carcinomas, and the Impact on Their Clinical Management

Derks, J. L., Leblay, N., Lantuejoul, S., Dingemans, A-M. C., Speel, E-J. M. & Fernandez-Cuesta, L., Jun 2018, In : Journal of Thoracic Oncology. 13, 6, p. 752-766 15 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Oncogenic Viruses in Skull Base Chordomas

Yakkioui, Y., Speel, E-J. M., Van Overbeeke, J. J., Boderie, M. J. M., Pujari, S., Hausen, A. Z., Wolffs, P. F. G. & Temel, Y., 1 Apr 2018, In : World Neurosurgery. 112, p. E7-E13 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Phosphatidylinositol 3-kinase p110δ expression in Merkel cell carcinoma

Chteinberg, E., Rennspiess, D., Sambo, R., Tauchmann, S., Kelleners-Smeets, N. W. J., Winnepenninckx, V., Speel, E., Kurz, A. K., Zenke, M. & zur Hausen, A., 2018, In : Oncotarget. 9, 51, p. 29565-29573

Research output: Contribution to journalArticleAcademicpeer-review

Prevalence and clinical association of gene mutations through multiplex mutation testing in patients with NSCLC: results from the ETOP Lungscape Project

Kerr, K. M., Dafni, U., Schulze, K., Thunnissen, E., Bubendorf, L., Hager, H., Finn, S., Biernat, W., Vliegen, L., Losa, J. H., Marchetti, A., Cheney, R., Warth, A., Speel, E. -J., Blackhall, F., Monkhorst, K., Lewintre, E. J., Tischler, V., Clark, C., Bertran-Alamillo, J. & 23 others, Meldgaard, P., Gately, K., Wrona, A., Vandenberghe, P., Felip, E., De Luca, G., Savic, S., Muley, T., Smit, E. F., Dingemans, A. -M. C., Priest, L., Baas, P., Camps, C., Weder, W., Polydoropoulou, V., Geiger, T. R., Kammler, R., Sumiyoshi, T., Molina, M. A., Shames, D. S., Stahel, R. A., Peters, S. & Etop Lungscape Consortium, 1 Jan 2018, In : Annals of Oncology. 29, 1, p. 200-208 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

The IGF pathway is activated in insulinomas but downregulated in metastatic disease

Henfling, M. E. R., Perren, A. A., Schmitt, A. M., Saddig, C. M., Starke, A. A., Riedl, R. G., Versleijen-Jonkers, Y. M. H., Sprij-Mooij, D. M., Ramaekers, F. C. S., Hofland, L. J. & Speel, E-J. M., Dec 2018, In : Endocrine-Related Cancer. 25, 12, p. 1005-1018 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Vismodegib-resistant basal cell carcinomas in basal cell nevus syndrome: Clinical approach and genetic analysis

Sinx, K., Roemen, G. M. J. M., van Zutven, V., Janssen, R., Speel, E., Steijlen, P., van Geel, M. & Mosterd, K., 2018, In : JAAD Case Reports. 4, 5, p. 408-11

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access

Chemotherapy for pulmonary large cell neuroendocrine carcinomas: does the regimen matter?

Derks, J. L., van Suylen, R. J., Thunnissen, E., den Bakker, M. A., Groen, H. J., Smit, E. F., Damhuis, R. A., van den Broek, E. C., Speel, E-J. M., Dingemans, A-M. C. & PALGA Grp, Jun 2017, In : European Respiratory Journal. 49, 6, 9 p., 1601838.

Research output: Contribution to journalArticleAcademicpeer-review

Chromosome instability in tumor resection margins of primary OSCC is a predictor of local recurrence

Pierssens, D. D. C. G., Borgemeester, M. C., van der Heijden, S. J. H., Peutz-Kootstra, C. J., Ruland, A. M., Haesevoets, A. M., Kessler, P. A. W. H., Kremer, B. & Speel, E-J. M., Mar 2017, In : Oral Oncology. 66, p. 14-21 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Dichotomous ALK-IHC Is a Better Predictor for ALK Inhibition Outcome than Traditional ALK-FISH in Advanced Non-Small Cell Lung Cancer

van der Wekken, A. J., Pelgrim, R., 't Hart, N., Werner, N., Mastik, M. F., Hendriks, L., van der Heijden, E. H. F. M., Looijen-Salamon, M., de langen, A. J., Staal-van den Brekel, J., Riemersma, S., van den Borne, B. E., Speel, E. J. M., Dingemans, A-M. C., Hiltermann, T. J. N., van den Berg, A., Timens, W., Schuuring, E. & Groen, H. J. M., 1 Aug 2017, In : Clinical Cancer Research. 23, 15, p. 4251-4258 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Externally validated HPV-based prognostic nomogram for oropharyngeal carcinoma patients yields more accurate predictions than TNM staging (vol 113, pg 324, 2014)

Velazquez, E. R., Hoebers, F., Aerts, H. J. W. L., Rietbergen, M. M., Brakenhoff, R. H., Leemans, R. C., Speel, E-J., Straetmans, J., Kremer, B. & Lambin, P., Aug 2017, In : Radiotherapy and Oncology. 124, 2, p. 337-338 2 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

Female urothelial cell carcinoma in a failed kidney graft of a male recipient

de Jongh, H. J. J., van Duijnhoven, E. M., Ruland, A., Hamid, M. M. A. A., Speel, E. J. M. & van de Beek, K., Oct 2017, In : Netherlands Journal of Medicine. 75, 8, p. 354-356 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

HPV Integration in Head and Neck Squamous Cell Carcinomas: Cause and Consequence

Speel, E. J. M., 2017, Recent Results in Cancer Research: HPV Infection in Head and Neck Cancer. 1 ed. Switserland, Vol. 206. p. 57-72 16 p. (Recent Results in Cancer Research).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Limited additive value of the Ki-67 proliferative index on patient survival in World Health Organization-classified pulmonary carcinoids

Swarts, D. R. A., Rudelius, M., Claessen, S. M. H., Cleutjens, J. P., Seidl, S., Volante, M., Ramaekers, F. C. S. & Speel, E. J. M., Feb 2017, In : Histopathology. 70, 3, p. 412-422 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

PET imaging of zirconium-89 labelled cetuximab: A phase I trial in patients with head and neck and lung cancer

van Loon, J., Even, A. J. G., Aerts, H. J. W. L., Ollers, M., Hoebers, F., van Elmpt, W., Dubois, L., Dingemans, A-M. C., Lalisang, R. I., Kempers, P., Brans, B., Winnepenninckx, V., Speel, E-J., Thunnissen, E., Smits, K. M., Boellaard, R., Vugts, D. J., De Ruysscher, D. & Lambin, P., Feb 2017, In : Radiotherapy and Oncology. 122, 2, p. 267-273 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Postzygotic mosaicism in basal cell naevus syndrome

Reinders, M. G. H. C., Boersma, H. J., Leter, E. M., Vreeburg, M., Paulussen, A. D. C., Arits, A. H. M. M., Roemen, G. M. J. M., Speel, E. J. M., Steijlen, P. M., van Geel, M. & Mosterd, K., Jul 2017, In : British Journal of Dermatology. 177, 1, p. 249-252 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Prevalence and clinical association of MET gene overexpression and amplification in patients with NSCLC: Results from the European Thoracic Oncology Platform (ETOP) Lungscape project

Bubendorf, L., Dafni, U., Schobel, M., Finn, S. P., Tischler, V., Sejda, A., Marchetti, A., Thunnissen, E., Verbeken, E. K., Warth, A., Sansano, I., Cheney, R., Speel, E. J. M., Nonaka, D., Monkhorst, K., Hager, H., Martorell, M., Savic, S., Kerr, K. M., Tan, Q. & 9 others, Tsourti, Z., Geiger, T. R., Kammler, R., Schulze, K., Das-Gupta, A., Shames, D., Peters, S., Stahel, R. A. & Lungscape Consortium, Sep 2017, In : Lung Cancer. 111, p. 143-149 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Prevalence of high-risk human papillomavirus infection and cancer gene mutations in nonmalignant tonsils

Ilmarinen, T., Munne, P., Hagstrom, J., Haglund, C., Auvinen, E., Virtanen, E. I., Haesevoets, A., Speel, E. J. M. & Aaltonen, L-M., Oct 2017, In : Oral Oncology. 73, p. 77-82 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Reviewing the current evidence supporting early B-cells as the cellular origin of Merkel cell carcinoma

Sauer, C. M., Haugg, A. M., Chteinberg, E., Rennspiess, D., Winnepenninckx, V., Speel, E. -J., Becker, J. C., Kurz, A. K. & zur Hausen, A., Aug 2017, In : Critical Reviews in Oncology/Hematology. 116, p. 99-105 7 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Why we should improve current practice of diagnosing and treating pulmonary large cell neuroendocrine carcinomas in patients with advanced disease

Derks, J., Van Suylen, R. J., Thunnissen, E., den Bakker, M., Groen, H., Smit, E., Damhuis, R., van den Broek, E., Speel, E-J. & Dingemans, A-M. C., 1 Oct 2017, In : European Respiratory Journal. 50, 4, 3 p., 1701658.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

2016

An Unmet Need in the WHO 2015 Biopsy Classification: Poorly Differentiated NSCCs with Positive Neuroendocrine Markers

Derks, J., Speel, E. & Dingemans, A-M., Feb 2016, In : Journal of Thoracic Oncology. 11, 2, p. E25-E26 3 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

Open Access
2 Citations (Scopus)

A Population-Based Analysis of Application of WHO Nomenclature in Pathology Reports of Pulmonary Neuroendocrine Tumors

Derks, J. L., van Suylen, R. J., Thunnissen, E., den Bakker, M. A., Smit, E. F., Groen, H. J. M., Speel, E. J. M. & Dingemans, A-M. C., Apr 2016, In : Journal of Thoracic Oncology. 11, 4, p. 593-602 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
1 Citation (Scopus)

A population based analysis of outcome of chemotherapy for metastatic pulmonary large cell neuroendocrine carcinomas: does the regimen matter?

Derks, J. L., van Suylen, R. J., Thunnissen, E., Den Bakker, M. A., Groen, H., Smit, E. F., Damhuis, R. A., Speel, E-J. & Dingemans, A-M. C., 1 Oct 2016, In : Annals of Oncology. 27

Research output: Contribution to journalConference Abstract/Poster in journalAcademic

Clinical features of large cell neuroendocrine carcinoma: a population-based overview

Derks, J. L., Hendriks, L. E., Buikhuisen, W. A., Groen, H. J. M., Thunnissen, E., van Suylen, R-J., Houben, R., Damhuis, R. A., Speel, E. J. M. & Dingemans, A-M. C., Feb 2016, In : European Respiratory Journal. 47, 2, p. 615-624

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Development and validation of a staging system for HPV-related oropharyngeal cancer by the International Collaboration on Oropharyngeal cancer Network for Staging (ICON-S): a multicentre cohort study

O'Sullivan, B., Huang, S. H., Su, J., Garden, A. S., Sturgis, E. M., Dahlstrom, K., Lee, N., Riaz, N., Pei, X., Koyfman, S. A., Adelstein, D., Burkey, B. B., Friborg, J., Kristensen, C. A., Gothelf, A. B., Hoebers, F., Kremer, B., Speel, E-J., Bowles, D. W., Raben, D. & 3 others, Karam, S. D., Yu, E. & Xu, W., Apr 2016, In : Lancet oncology. 17, 4, p. 440-451

Research output: Contribution to journalArticleAcademicpeer-review

24 Citations (Scopus)

Frequent detection of human polyomavirus 6 in keratoacanthomas

Beckervordersandforth, J., Pujari, S., Rennspiess, D., Speel, E. J. M., Winnepenninckx, V., Diaz, C., Weyers, W., Haugg, A. M., Kurz, A. K. & zur Hausen, A., 7 Jul 2016, In : Diagnostic Pathology. 11, 58.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
4 Citations (Scopus)

Identification of CD90 as Putative Cancer Stem Cell Marker and Therapeutic Target in Insulinomas

Buishand, F. O., Arkesteijn, G. J. A., Feenstra, L. R., Oorsprong, C. W. D., Mestemaker, M., Starke, A., Speel, E-J. M., Kirpensteijn, J. & Mol, J. A., 1 Jun 2016, In : Stem Cells and Development. 25, 11, p. 826-835

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)