20012020

Research output per year

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Research Output

2020

Analysis of 4-fluoroamphetamine in cerumen after controlled oral application

Meier, S. I., Petzel-Witt, S., Schubert-Zsilavecz, M., de Sousa Fernandes Perna, E. B., Theunissen, E. L., Ramaekers, J. G. & Toennes, S. W., 4 Apr 2020, In : Drug Testing and Analysis. 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Blunted highs: Pharmacodynamic and behavioral models of cannabis tolerance

Ramaekers, J. G., Mason, N. L. & Theunissen, E. L., 31 Jan 2020, In : European Neuropsychopharmacology.

Research output: Contribution to journalArticleAcademicpeer-review

Cognitive and subjective effects of different low 'micro' doses of LSD in a placebo-controlled study

Hutten, N., Mason, N., Dolder, P., Theunissen, E., Liechti, M., Feilding, A., Ramaekers, J. & Kuypers, K., Feb 2020, In : European Neuropsychopharmacology. 31, S1, p. S63-S64 3 p.

Research output: Contribution to journalConference Abstract/Poster in journalAcademic

Excretion of 4-fluoroamphetamine and three metabolites in urine after controlled oral ingestion

Toennes, S. W., Schneider, D., Pogoda, W., Paulke, A., Wunder, C., Theunissen, E. L., Perna, E. B. D. S. F. & Ramaekers, J. G., 3 Feb 2020, In : Journal of Pharmaceutical and Biomedical Analysis. 179, 8 p., 113008.

Research output: Contribution to journalArticleAcademicpeer-review

Mephedrone and Alcohol Interactions in Humans

Papaseit, E., Pérez-Mañá, C., de Sousa Fernandes Perna, E. B., Olesti, E., Mateus, J., Kuypers, K. P. C., Theunissen, E. L., Fonseca, F., Torrens, M., Ramaekers, J. G., de la Torre, R. & Farré, M., 28 Jan 2020, In : Frontiers in Pharmacology. 10, 17 p., 1588.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Semiquantitative Activity-Based Detection of JWH-018, a Synthetic Cannabinoid Receptor Agonist, in Oral Fluid after Vaping

Cannaert, A., Fernandez, M. D. M. R., Theunissen, E. L., Ramaekers, J. G., Wille, S. M. R. & Stove, C. P., 21 Apr 2020, In : Analytical Chemistry. 92, 8, p. 6065-6071 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

2019
Open Access

Cannabis induced increase in striatal glutamate associated with loss of functional corticostriatal connectivity

Mason, N. L., Theunissen, E. L., Hutten, N. R. P. W., Tse, D. H. Y., Toennes, S. W., Stiers, P. & Ramaekers, J. G., Dec 2019, In : European Neuropsychopharmacology. 29, 2, p. 247-256 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Cocaine enhances figural, but impairs verbal 'flexible' divergent thinking

Hutten, N. R. P. W., Steenbergen, L., Colzato, L. S., Hommel, B., Theunissen, E. L., Ramaekers, J. G. & Kuypers, K. P. C., Jul 2019, In : European Neuropsychopharmacology. 29, 7, p. 813-824 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Pharmacokinetic properties of 4-fluoroamphetamine in serum and oral fluid after oral ingestion

Toennes, S. W., Schneider, D., Pogoda, W., Paulke, A., Wunder, C., Theunissen, E. L., Kuypers, K. P. C., de Sousa Fernandes Perna, E. & Ramaekers, J. G., Jul 2019, In : Drug Testing and Analysis. 11, 7, p. 1028-1034 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Reduced responsiveness of the reward system is associated with tolerance to cannabis impairment in chronic users

Mason, N. L., Theunissen, E. L., Hutten, N. R. P. W., Tse, D. H. Y., Toennes, S. W., Jansen, J. F. A., Stiers, P. & Ramaekers, J. G., 22 Dec 2019, In : Addiction Biology. 9 p., e12870.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2018

A single dose of cocaine enhances prospective memory performance

Hutten, N. RPW., Kuypers, K. PC., van Wel, J. HP., Theunissen, E. L., Toennes, S. W., Verkes, R-J. & Ramaekers, J. G., Aug 2018, In : Journal of Psychopharmacology. 32, 8, p. 883–892 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Depressive mood ratings are reduced by MDMA in female polydrug ecstasy users homozygous for the l-allele of the serotonin transporter

Kuypers, K. P. C., de la Torre, R., Farre, M., Xicota, L., Perna, E. B. D. S. F., Theunissen, E. L. & Ramaekers, J. G., 18 Jan 2018, In : Scientific Reports. 8, 7 p., 1061.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Drug liking and wanting, not impulsive action or reflection is increased by 4-fluoroamphetamine

Kuypers, K. P. C., de Sousa Fernandes Perna, E. B., Dolder, P. C., Toennes, S. W., Theunissen, E. L., Mason, N. L., Hutten, N. R. P. W. & Ramaekers, J. G., Aug 2018, In : Psychopharmacology. 235, 8, p. 2349-2356 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Excretion of metabolites of the synthetic cannabinoid JWH-018 in urine after controlled inhalation

Toennes, S. W., Geraths, A., Pogoda, W., Paulke, A., Wunder, C., Theunissen, E. L. & Ramaekers, J. G., 20 Feb 2018, In : Journal of Pharmaceutical and Biomedical Analysis. 150, p. 162-168 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Pharmacokinetic properties of the synthetic cannabinoid JWH-018 in oral fluid after inhalation

Toennes, S. W., Geraths, A., Pogoda, W., Paulke, A., Wunder, C., Theunissen, E. L. & Ramaekers, J. G., Apr 2018, In : Drug Testing and Analysis. 10, 4, p. 644-650 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Brain reactivity to alcohol and cannabis marketing during sobriety and intoxication

de Sousa Fernandes Perna, E. B., Theunissen, E. L., Kuypers, K. P. C., Evers, E. A., Stiers, P., Toennes, S. W., Witteman, J., van Dalen, W. & Ramaekers, J. G., May 2017, In : Addiction Biology. 22, 3, p. 823–832 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Pharmacokinetic properties of the synthetic cannabinoid JWH-018 and of its metabolites in serum after inhalation

Toennes, S. W., Geraths, A., Pogoda, W., Paulke, A., Wunder, C., Theunissen, E. L. & Ramaekers, J. G., 5 Jun 2017, In : Journal of Pharmaceutical and Biomedical Analysis. 140, p. 215-222 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

2016

Amphetamine & methamphetamine: pharmacokinetics and pharmacodynamics

Kuypers, K. P. C., Theunissen, E. L. & Ramaekers, J. G., 18 Oct 2016, The SAGE handbook of drug and alcohol studies: Biological approaches. Wolff, K., White, J. & Karch, S. (eds.). SAGE, p. 131-151

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Ayahuasca enhances creative divergent thinking while decreasing conventional convergent thinking

Kuypers, K. P. C., Riba, J., de la Fuente Revenga, M., Barker, S., Theunissen, E. L. & Ramaekers, J. G., Sep 2016, In : Psychopharmacology. 233, 18, p. 3395–3403 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
1 Citation (Scopus)
184 Downloads (Pure)

Cannabis and tolerance: acute drug impairment as a function of cannabis use history

Ramaekers, J. G., van Wel, J. H., Spronk, D. B., Toennes, S. W., Kuypers, K. P. C., Theunissen, E. L. & Verkes, R. J., 2 Sep 2016, In : Scientific Reports. 6, 1 p., 31939.

Research output: Contribution to journalErratum / corrigendumAcademic

Open Access
File
114 Downloads (Pure)

Cannabis and tolerance: acute drug impairment as a function of cannabis use history

Ramaekers, J. G., van Wel, J. H., Spronk, D. B., Toennes, S. W., Kuypers, K. P. C., Theunissen, E. L. & Verkes, R. J., 26 May 2016, In : Scientific Reports. 6, 8 p., 26843.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
2 Citations (Scopus)
170 Downloads (Pure)

MEPHEDRONE EFFECTS ON ACUTE ALCOHOL INTOXICATION

Papaseit, E., Perez-Mana, C., de Souza, E., Mateus, J. A., Olesti, E., Theunissen, E., Kuypers, K., Ramaekers, J., Fonseca, F., Torrens, M., de la Torre, R. & Farre, M., Oct 2016, p. 28-28. 1 p.

Research output: Contribution to conferenceAbstractAcademic

Neurocognitive performance following acute mephedrone administration, with and without alcohol

de Sousa Fernandes Perna, E. B., Papaseit, E., Pérez-Mañá, C., Mateus, J., Theunissen, E. L., Kuypers, K. P. C., de la Torre, R., Farré, M. & Ramaekers, J. G., Dec 2016, In : Journal of Psychopharmacology. 30, 12, p. 1305–1312 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

On-the-road driving performance after use of the antihistamines mequitazine and l-mequitazine, alone and with alcohol

van der Sluiszen, N. N. J. J. M., Vermeeren, A., Jongen, S., Theunissen, E. L., van Oers, A. C. M., Van Leeuwen, C. J., Maret, A., Desforges, C., Delarue, A. & Ramaekers, J. G., Sep 2016, In : Psychopharmacology. 233, 18, p. 3461–3469 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
1 Citation (Scopus)
161 Downloads (Pure)

P.6.f.004 - Ayahuasca enhances creative divergent thinking

Kuypers, K. P. C., Riba, J., De la Fuente Revenga, M., Barker, S., Theunissen, E. L. & Ramaekers, J. G., Oct 2016, In : European Neuropsychopharmacology. 26, Supplement 2, p. S705-S706 1 p.

Research output: Contribution to journalConference Abstract/Poster in journalAcademic

1 Citation (Scopus)

Subjective aggression during alcohol and cannabis intoxication before and after aggression exposure

De Sousa Fernandes Perna, E. B., Theunissen, E. L., Kuypers, K. P. C., Toennes, S. W. & Ramaekers, J. G., Sep 2016, In : Psychopharmacology. 233, 18, p. 3331–3340 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
2 Citations (Scopus)
159 Downloads (Pure)

Verbal memory impairment in polydrug ecstasy users: A clinical perspective

Kuypers, K. P. C., Theunissen, E. L., van Wel, J. H. P., de Sousa, E. B., Perna, F., Linssen, A., Sambeth, A., Schultz, B. G. & Ramaekers, J. G., 23 Feb 2016, In : PLOS ONE. 11, 2, 0149438.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
1 Citation (Scopus)
152 Downloads (Pure)
2015

Cannabis and cocaine decrease cognitive impulse control and functional corticostriatal connectivity in drug users with low activity DBH genotypes

Ramaekers, J. G., van Wel, J. H., Spronk, D., Franke, B., Kenis, G., Toennes, S. W., Kuypers, K. P. C., Theunissen, E. L., Stiers, P. & Verkes, R. J., 14 Dec 2015, In : Brain Imaging and Behavior. p. 1254–1263

Research output: Contribution to journalArticleAcademicpeer-review

Emotion recognition during cocaine intoxication

Kuypers, K., Steenbergen, L., Theunissen, E., Toennes, S. W. & Ramaekers, J. G., 1 Jan 2015, p. S213-S213.

Research output: Contribution to conferencePosterAcademic

MDMA, cannabis, and cocaine produce acute dissociative symptoms

van Heugten-Van der Kloet, D., Giesbrecht, T., van Wel, J., Bosker, W. M., Kuypers, K. P. C., Theunissen, E. L., Spronk, D. B., Verkes, R. J., Merckelbach, H. & Ramaekers, J. G., 30 Aug 2015, In : Psychiatry Research. 228, 3, p. 907-912 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Psychedelic symptoms of cannabis and cocaine use as a function of trait impulsivity

van Wel, J. H. P., Spronk, D. B., Kuypers, K. P. C., Theunissen, E. L., Toennes, S. W., Verkes, R. J. & Ramaekers, J. G., 1 Mar 2015, In : Journal of Psychopharmacology. 29, 3, p. 324-334 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Rivastigmine but not vardenafil reverses cannabis-induced impairment of verbal memory in healthy humans

Theunissen, E. L., Heckman, P., de Sousa Fernandes Perna, E. B., Kuypers, K. P. C., Sambeth, A., Blokland, A., Prickaerts, J., Toennes, S. W. & Ramaekers, J. G., 1 Jan 2015, In : Psychopharmacology. 232, 2, p. 343-353 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)
2014

Memory and mood during MDMA intoxication, with and without memantine pretreatment

de Sousa Fernandes Perna, E. B., Theunissen, E. L., Kuypers, K. P. C., Heckman, P., de la Torre, R., Farre, M. & Ramaekers, J. G., Dec 2014, In : Neuropharmacology. 87, p. 198-205 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)
2013

A Randomized Trial on the Acute and Steady-State Effects of a New Antidepressant, Vortioxetine (Lu AA21004), on Actual Driving and Cognition

Theunissen, E., Street, D., Hojer, A. M., Vermeeren, A., van Oers, A. & Ramaekers, J. G., Jun 2013, In : Clinical Pharmacology & Therapeutics. 93, 6, p. 493-501 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

39 Citations (Scopus)

Central nervous system-impairing effects of hydroxyzine as a function of histamine availability

Conen, S., Theunissen, E. L., Vermeeren, A., Sambeth, A. & Ramaekers, J. G., Apr 2013, In : Journal of Clinical Psychopharmacology. 33, 2, p. 276-279 4 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

Influence of Ethanol on the Pharmacokinetic Properties of (9)-Tetrahydrocannabinol in Oral Fluid

Toennes, S. W., Schneider, K., Wunder, C., Kauert, G. F., Moeller, M. R., Theunissen, E. L. & Ramaekers, J. G., Apr 2013, In : Journal of Analytical Toxicology. 37, 3, p. 152-158 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

Methylphenidate reduces functional connectivity of nucleus accumbens in brain reward circuit

Ramaekers, J. G., Evers, E. A., Theunissen, E. L., Kuypers, K. P. C., Goulas, A. & Stiers, P., Sep 2013, In : Psychopharmacology. 229, 2, p. 219-226 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

15 Citations (Scopus)

Psychomotor function in chronic daily Cannabis smokers during sustained abstinence

Bosker, W. M., Karschner, E. L., Lee, D., Goodwin, R. S., Hirvonen, J., Innis, R. B., Theunissen, E. L., Kuypers, K. P. C., Huestis, M. A. & Ramaekers, J. G., 2 Jan 2013, In : PLOS ONE. 8, 1, 7 p., 53127.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
25 Citations (Scopus)

Single doses of THC and cocaine decrease proficiency of impulse control in heavy cannabis users

van Wel, J. H. P., Kuypers, K. P. C., Theunissen, E. L., Toennes, S. W., Spronk, D. B., Verkes, R. J. & Ramaekers, J. G., Dec 2013, In : British Journal of Pharmacology. 170, 7, p. 1410-1420 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Scopus)

The role of P-glycoprotein in CNS antihistamine effects

Conen, S., Theunissen, E. L., Vermeeren, A., van Ruitenbeek, P., Stiers, P., Mehta, M. A., Toennes, S. W. & Ramaekers, J. G., 1 Jan 2013, In : Psychopharmacology. 229, 1, p. 9-19

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)
2012

A placebo-controlled study to assess Standardized Field Sobriety Tests performance during alcohol and cannabis intoxication in heavy cannabis users and accuracy of point of collection testing devices for detecting THC in oral fluid

Bosker, W. M., Theunissen, E. L., Conen, S., Kuypers, K. P. C., Jeffery, W. K., Walls, H. C., Kauert, G. F., Toennes, S. W., Moeller, M. R. & Ramaekers, J. G., Oct 2012, In : Psychopharmacology. 223, 4, p. 439-446 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

19 Citations (Scopus)

Effects of acute MDMA intoxication on mood and impulsivity: role of the 5-HT(2) and 5-HT(1) receptors

van Wel, J. H. P., Kuypers, K. P. C., Theunissen, E. L., Bosker, W. M., Bakker, K. & Ramaekers, J. G., 10 Jul 2012, In : PLOS ONE. 7, 7, 8 p., 40187.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
20 Citations (Scopus)