1993 …2019

Research output per year

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Research Output

2017

Why septal motion is a marker of right ventricular failure in pulmonary arterial hypertension: mechanistic analysis using a computer model

Palau-Caballero, G., Walmsley, J., Van Empel, V., Lumens, J. & Delhaas, T., Apr 2017, In : American Journal of Physiology-heart and Circulatory Physiology. 312, 4, p. H691-H700 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2016

Abnormal Ventricular and Aortic Wall Properties Can Cause Inconsistencies in Grading Aortic Regurgitation Severity: A Computer Simulation Study

Palau-Caballero, G., Walmsley, J., Gorcsan, J. III., Lumens, J. & Delhaas, T., Nov 2016, In : Journal of the American Society of Echocardiography. 29, 11, p. 1122-1130.e4

Research output: Contribution to journalArticleAcademicpeer-review

A guide to uncertainty quantification and sensitivity analysis for cardiovascular applications

Eck, V. G., Donders, W. P., Sturdy, J., Feinberg, J., Delhaas, T., Hellevik, L. R. & Huberts, W., Aug 2016, In : International Journal for Numerical Methods in Biomedical Engineering. 32, 8, e02755.

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Application of an Adaptive Polynomial Chaos Expansion on Computationally Expensive Three-Dimensional Cardiovascular Models for Uncertainty Quantification and Sensitivity Analysis

Quicken, S., Donders, W. P., van Disseldorp, E. M. J., Gashi, K., Mees, B. M. E., van de Vosse, F. N., Lopata, R. G. P., Delhaas, T. & Huberts, W., Dec 2016, In : Journal of Biomechanical Engineering-Transactions of the Asme. 138, 12

Research output: Contribution to journalArticleAcademicpeer-review

Can significance of aortic sinus vortices be assessed using the assumptions in the model of Aboelkassem et al.?

Spronck, B., Walmsley, J., Palau-Caballero, G., Reesink, K. D. & Delhaas, T., 21 Jan 2016, In : Journal of Theoretical Biology. 389, p. 304-305

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Carotid Artery Applanation Tonometry Does Not Cause Significant Baroreceptor Activation

Spronck, B., Delhaas, T., op het Roodt, J. & Reesink, K. D., Mar 2016, In : American Journal of Hypertension. 29, 3, p. 299-302

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Comparison of ECG-based physiological markers for hypoxia in a preterm ovine model

Zwanenburg, A., Hermans, B. J. M., Andriessen, P., Niemarkt, H. J., Jellema, R. K., Ophelders, D. R. M. G., Vullings, R., Wolfs, T. G. A. M., Kramer, B. W. & Delhaas, T., Jun 2016, In : Pediatric Research. 79, 6, p. 907-915

Research output: Contribution to journalArticleAcademicpeer-review

Head orientation should be considered in ultrasound studies on carotid artery distensibility

Holtackers, R. J., Spronck, B., Heusinkveld, M. H. G., Crombag, G., op het Roodt, J., Delhaas, T., Kooi, E., Reesink, K. D. & Hermeling, E., Aug 2016, In : Journal of Hypertension. 34, 8, p. 1551-1555

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Heart Rate Dependency of Large Artery Stiffness

Tan, I., Spronck, B., Kiat, H., Barin, E., Reesink, K. D., Delhaas, T., Avolio, A. P. & Butlin, M., Jul 2016, In : Hypertension. 68, 1, p. 236-242

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

In vitro and in vivo evaluation of drug-eluting microspheres designed for transarterial chemoembolization therapy

Wang, Y., Molin, D. G. M., Sevrin, C., Grandfils, C., van den Akker, N. M. S., Gagliardi, M., Knetsch, M. L., Delhaas, T. & Koole, L., 30 Apr 2016, In : International Journal of Pharmaceutics. 503, 1-2, p. 150-162

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Mechano-chemical Interactions in Cardiac Sarcomere Contraction: A Computational Modeling Study

Dupuis, L. J., Lumens, J., Arts, T. & Delhaas, T., Oct 2016, In : PLoS Computational Biology. 12, 10

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Mesenchymal Stromal Cell-Derived Extracellular Vesicles Protect the Fetal Brain After Hypoxia-Ischemia

Ophelders, D. R. M. G., Wolfs, T. G. A. M., Jellema, R. K., Zwanenburg, A., Andriessen, P., Delhaas, T., Ludwig, A-K., Radtke, S., Peters, V., Janssen, L., Giebel, B. & Kramer, B. W., Jun 2016, In : Stem Cells Translational Medicine. 5, 6, p. 754-763

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
12 Citations (Scopus)

New insights from a computational model on the relation between pacing site and CRT response

Pluijmert, M., Bovendeerd, P. H. M., Lumens, J., Vernooy, K., Prinzen, F. & Delhaas, T., Dec 2016, In : EP Europace. 18, Suppl_4, p. iv94–iv103 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Normal ranges for fetal electrocardiogram values for the healthy fetus of 18-24 weeks of gestation: a prospective cohort study

Verdurmen, K., Lempersz, C., Vullings, R., Schroer, C., Delhaas, T., van Laar, J. O. E. H. & Oei, S. G., 17 Aug 2016, In : BMC Pregnancy and Childbirth. 16, 227.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Preoperative Sildenafil administration in children undergoing cardiac surgery: a randomized controlled preconditioning study

Upendra Walavalkar, V., Evers, E., Pujar, S., Viralam, K., Maiya, S., Frerich, S., John, C., Rao, S., Reddy, C., Spronck, B., Prinzen, F., Delhaas, T. & Vanagt, W. Y., May 2016, In : European Journal of Cardio-Thoracic Surgery. 49, 5, p. 1403-1410

Research output: Contribution to journalArticleAcademicpeer-review

Right Ventricular Imaging and Computer Simulation for Electromechanical Substrate Characterization in Arrhythmogenic Right Ventricular Cardiomyopathy

Mast, T. P., Teske, A. J., Walmsley, J., van der Heijden, J. F., van Es, R., Prinzen, F. W., Delhaas, T., van Veen, T. A., Loh, P., Doevendans, P. A., Cramer, M. J. & Lumens, J., 15 Nov 2016, In : Journal of the American College of Cardiology. 68, 20, p. 2185-2197

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Septal flash and septal rebound stretch have different underlying mechanisms

Walmsley, J., Huntjens, P. R., Prinzen, F. W., Delhaas, T. & Lumens, J., 1 Feb 2016, In : American Journal of Physiology-heart and Circulatory Physiology. 310, 3, p. H394-H403

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

Systemic interleukin-2 administration improves lung function and modulates chorioamnionitis-induced pulmonary inflammation in the ovine fetus

Willems, M. G. M., Ophelders, D. R. M. G., Nikiforou, M., Jellema, R. K., Butz, A., Delhaas, T., Kramer, B. W. & Wolfs, T. G. A. M., 1 Jan 2016, In : American Journal of Physiology-Lung Cellular and Molecular Physiology. 310, 1, p. L1-L7

Research output: Contribution to journalArticleAcademicpeer-review

2015

A constitutive modeling interpretation of the relationship among carotid artery stiffness, blood pressure, and age in hypertensive subjects

Spronck, B., Heusinkveld, M. H. G., Donders, W. P., de Lepper, A. G. W., Op't Roodt, J., Kroon, A. A., Delhaas, T. & Reesink, K. D., 15 Mar 2015, In : American Journal of Physiology-heart and Circulatory Physiology. 308, 6, p. H568-H582

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Assessment and comparison of left ventricular shear in normal and situs inversus totalis hearts by means of magnetic resonance tagging

Rossi, A. C., Pluijmert, M., Bovendeerd, P. H. M., Kroon, W., Arts, T. & Delhaas, T., 1 Mar 2015, In : American Journal of Physiology-heart and Circulatory Physiology. 308, 5, p. H416-H423

Research output: Contribution to journalArticleAcademicpeer-review

Assessment of septal motion abnormalities in left bundle branch block patients using computer simulations

Huntjens, P. R., Walmsley, J., Wu, V., Delhaas, T., Axel, L. & Lumens, J., 2015, Functional Imaging and Modeling of the Heart 2015. Berlin Heidelberg: Springer Verlag, p. 40-47

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

1 Citation (Scopus)

Comparison of septal strain patterns in dyssynchronous heart failure between speckle tracking echocardiography vendor systems

van Everdingen, W. M., Paiman, M-L., van Deursen, C. J. M., Cramer, M. J., Vernooy, K., Delhaas, T. & Prinzen, F. W., 2015, In : Journal of Electrocardiology. 48, 4, p. 609-616

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

Computer modelling for better diagnosis and therapy of patients by cardiac resynchronisation therapy

Pluijmert, M., Lumens, J., Potse, M., Delhaas, T., Auricchio, A. & Prinzen, F. W., 2015, In : Arrhythmia & Electrophysiology Review. 4, 1, p. 62-67 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Differentiating Electromechanical From Non-Electrical Substrates of Mechanical Discoordination to Identify Responders to Cardiac Resynchronization Therapy

Lumens, J., Tayal, B., Walmsley, J., Delgado-Montero, A., Huntjens, P. R., Schwartzman, D., Althouse, A. D., Delhaas, T., Prinzen, F. W. & Gorcsan, J., Sep 2015, In : Circulation-Cardiovascular Imaging. 8, 9, e003744.

Research output: Contribution to journalArticleAcademicpeer-review

16 Citations (Scopus)

Fast Simulation of Mechanical Heterogeneity in the Electrically Asynchronous Heart Using the MultiPatch Module

Walmsley, J., Arts, T., Derval, N., Bordachar, P., Cochet, H., Ploux, S., Prinzen, F. W., Delhaas, T. & Lumens, J., Jul 2015, In : PLoS Computational Biology. 11, 7, e1004284.

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Functional Imaging and Modeling of the Heart 2015

van Assen, H., Bovendeerd, P. H. & Delhaas, T., 2015, Springer Verlag.

Research output: Book/ReportBookAcademic

Hemodynamics in aortic regurgitation simulated using a computational cardiovascular system model

Palau Caballero, G., Walmsley, J., Rudenick, P., Evangelista, A., Lumens, J. & Delhaas, T., 2015, Functional Imaging and Modeling of the Heart 2015. Berlin Heidelberg: Springer Verlag, p. 364-372

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

1 Citation (Scopus)

How to choose myofiber orientation in a biventricular finite element model?

Pluijmert, M., Prinzen, F., Flores de la Parra, A. F., Kroon, W., Delhaas, T. & Bovendeerd, P. H., 2015, Functional Imaging and Modeling of the Heart 2015. Berlin Heidelberg: Springer Verlag, p. 373-381

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

In vivo electromechanical assessment of heart failure patients with prolonged QRS duration

Kroon, W., Lumens, J., Potse, M., Suerder, D., Klersy, C., Regoli, F., Murzilli, R., Moccetti, T., Delhaas, T., Krause, R., Prinzen, F. W. & Auricchio, A., Jun 2015, In : Heart Rhythm. 12, 6, p. 1259-1267

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)

Longitudinal Strain "Think Globally, Track Locally"

Lumens, J., Prinzen, F. W. & Delhaas, T., Dec 2015, In : JACC-Cardiovascular Imaging. 8, 12, p. 1360-1363

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Management of children with dilated cardiomyopathy in The Netherlands: Implications of a low early transplantation rate

den Boer, S. L., van Osch-Gevers, M. L., van Ingen, G., Sarvaas, G. J. D. M., van Iperen, G. G., Tanke, R. B., Backx, A. P. C. M., ten Harkel, A. D. J., Helbing, W. A., Delhaas, T., Bogers, A. J. J. C., Rammeloo, L. A. J. & Dalinghaus, M., Jul 2015, In : Journal of Heart and Lung Transplantation. 34, 7, p. 963-969

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Multipotent adult progenitor cells for hypoxic-ischemic injury in the preterm brain

Jellema, R. K., Ophelders, D. R. M. G., Zwanenburg, A., Nikiforou, M., Delhaas, T., Andriessen, P., Mays, R. W., Deans, R., Germeraad, W. T. V., Wolfs, T. G. A. M. & Kramer, B. W., 23 Dec 2015, In : Journal of Neuroinflammation. 12, p. 241

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)
7 Citations (Scopus)

Pressure-dependence of arterial stiffness: potential clinical implications

Spronck, B., Heusinkveld, M. H. G., Vanmolkot, F. H., 't Roodt, J. O., Hermeling, E., Delhaas, T., Kroon, A. A. & Reesink, K. D., Feb 2015, In : Journal of Hypertension. 33, 2, p. 330-338

Research output: Contribution to journalArticleAcademicpeer-review

15 Citations (Scopus)

Responses of the spleen to intraamniotic lipopolysaccharide exposure in fetal sheep

Kuypers, E., Willems, M. G. M., Jellema, R. K., Kemp, M. W., Newnham, J. P., Delhaas, T., Kallapur, S. G., Jobe, A. H., Wolfs, T. G. A. M. & Kramer, B. W., Jan 2015, In : Pediatric Research. 77, 1, p. 29-35

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Treatment of pulmonary arterial hypertension in children

Latus, H., Delhaas, T., Schranz, D. & Apitz, C., Apr 2015, In : Nature Reviews Cardiology. 12, 4, p. 244-254

Research output: Contribution to journalArticleAcademicpeer-review

14 Citations (Scopus)

Using trend templates in a neonatal seizure algorithm improves detection of short seizures in a foetal ovine model

Zwanenburg, A., Andriessen, P., Jellema, R. K., Niemarkt, H. J., Wolfs, T. G. A. M., Kramer, B. W. & Delhaas, T., Mar 2015, In : Physiological Measurement. 36, 3, p. 369-384

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)
2014

Altered canonical Wingless-It signaling in the ovine fetal lung after exposure to intra-amniotic lipopolysaccharide and antenatal betamethasone

Kuypers, E., Willems, M. G. M., Collins, J. J. P., Wolfs, T. G. A. M., Nitsos, I., Pillow, J. J., Polglase, G. R., Kemp, M. W., Newnham, J. P., Delhaas, T., Jobe, A. H., Kallapur, S. G. & Kramer, B. W., Feb 2014, In : Pediatric Research. 75, 2, p. 281-287

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)
9 Citations (Scopus)

Clinical correlates of echocardiographic tissue velocity imaging abnormalities of the left atrial wall during atrial fibrillation

Limantoro, I., de Vos, C. B., Delhaas, T., Weijs, B., Blaauw, Y., Schotten, U., Kietselaer, B., Pisters, R. & Crijns, H. J. G. M., Nov 2014, In : EP Europace. 16, 11, p. 1546-1553

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

Effects of activation pattern and active stress development on myocardial shear in a model with adaptive myofiber reorientation

Pluijmert, M., Bovendeerd, P. H. M., Kroon, W., Prinzen, F. W. & Delhaas, T., Feb 2014, In : American Journal of Physiology-heart and Circulatory Physiology. 306, 4, p. H538-H546

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

Influence of left ventricular lead position relative to scar location on response to cardiac resynchronization therapy: a model study

Huntjens, P. R., Walmsley, J., Ploux, S., Bordachar, P., Prinzen, F. W., Delhaas, T. & Lumens, J., Nov 2014, In : EP Europace. 16 Suppl 4, p. iv62-iv68

Research output: Contribution to journalArticleAcademicpeer-review

10 Citations (Scopus)

Long-Term Risk to Develop Hypertension in Women With Former Preeclampsia: A Longitudinal Pilot Study

Ghossein-Doha, C., Spaanderman, M., van Kuijk, S. M. J., Kroon, A. A., Delhaas, T. & Peeters, L., 1 Jan 2014, In : Reproductive Sciences. 21, 7, p. 846-853

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)

Mechano-electrical coupling as framework for understanding functional remodeling during LBBB and CRT

Kuijpers, N. H. L., Hermeling, E., Lumens, J., ten Eikelder, H. M. M., Delhaas, T. & Prinzen, F. W., 15 Jun 2014, In : American Journal of Physiology-heart and Circulatory Physiology. 306, 12, p. H1644-H1659

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Satellite cells in human skeletal muscle; from birth to old age.

Verdijk, L. B., Snijders, T., Drost, M., Delhaas, T., Kadi, F. & van Loon, L. J., Apr 2014, In : Age. 36, 2, p. 545-557 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

40 Citations (Scopus)
1 Citation (Scopus)

Tissue velocity imaging of the left atrium predicts response to flecainide in patients with acute atrial fibrillation

Limantoro, I., De Vos, C. B., Delhaas, T., Marcos, E., Blaauw, Y., Weijs, B., Tieleman, R. G., Pisters, R., Schotten, U., Van Gelder, I. C. & Crijns, H. J. G. M., Mar 2014, In : Heart Rhythm. 11, 3, p. 478-484

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

Ureter Smooth Muscle Cell Orientation in Rat Is Predominantly Longitudinal

Spronck, B., Merken, J. J., Reesink, K. D., Kroon, W. & Delhaas, T., 21 Jan 2014, In : PLOS ONE. 9, 1, e86207.

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)