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Research Output 2005 2019

2019

A gain-of-function sodium channel beta 2-subunit mutation in painful diabetic neuropathy

May 2019, In : Molecular Pain. 15, p. 1-14 14 p., 1744806919849802.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Assessment of fibroblast nuclear morphology aids interpretation of LMNA variants

van Tienen, F., Lindsey, P., Kamps, M., Krapels, I., Ramaekers, F., Brunner, H., van den Wijngaard, A. & Broers, J., Mar 2019, In : European Journal of Human Genetics. 27, 3, p. 389–399 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Healthy, mtDNA-mutation free mesoangioblasts from mtDNA patients qualify for autologous therapy

van Tienen, F., Zelissen, R., Timmer, E., van Gisbergen, M., Lindsey, P., Quattrocelli, M., Sampaolesi, M., Mulder-den Hartog, E., de Coo, I. & Smeets, H., 21 Dec 2019, In : Stem Cell Research & Therapy. 10, 1, 10 p., 405.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Yield of peripheral sodium channels gene screening in pure small fibre neuropathy

Eijkenboom, I., Sopacua, M., Hoeijmakers, J., de Greef, B., Lindsey, P., Almomani, R., Marchi, M., Vanoevelen, J., J.M. Smeets, H., Waxman, S. G., Lauria, G., Merkies, I., Faber, K. & Gerrits, M., Mar 2019, In : Journal of Neurology Neurosurgery and Psychiatry. 90, 3, p. 342-352 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

2018

Mutation-specific effects in germline transmission of pathogenic mtDNA variants

Otten, A. B. C., Sallevelt, S. C. E. H., Carling, P. J., Dreesen, J. C. F. M., Drusedau, M., Spierts, S., Paulussen, A. D. C., de Die-Smulders, C. E. M., Herbert, M., Chinnery, P. F., Samuels, D. C., Lindsey, P. & Smeets, H. J. M., 1 Jul 2018, In : Human Reproduction. 33, 7, p. 1331-1341 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

2017

Network topology of NaV1.7 mutations in sodium channel-related painful disorders

Kapetis, D., Sassone, J., Yang, Y., Galbardi, B., Xenakis, M. N., Westra, R. L., Szklarczyk, R., Lindsey, P., Faber, C. G., Gerrits, M., Merkies, I. S. J., Dib-Hajj, S. D., Mantegazza, M., Waxman, S. G., J.M. Smeets, H. & Lauria, G., 24 Feb 2017, In : BMC Systems Biology. 11, 16 p., 28.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2016

Assessing biases of information contained in pedigrees for the classification of BRCA-genetic variants: a study arising from the ENIGMA analytical working group

Kerkhofs, C. H. H., Spurdle, A. B., Lindsey, P. J., Goldgar, D. E. & Gomez-Garcia, E. B., 30 Apr 2016, In : Hereditary Cancer in Clinical Practice. 14, 10.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
5 Citations (Scopus)

Hypertrophic remodelling in cardiac regulatory myosin light chain (MYL2) founder mutation carriers

Claes, G. R. F., van Tienen, F. H. J., Lindsey, P., Krapels, I. P. C., van den Enden, A., Hoos, M., Barrois, Y. E. G., Janssen, J., Paulussen, A. D. C., Sels, J-W. E. M., Kuijpers, S. H. H., van Tintelen, J. P., van den Berg, M. P., Heesen, W. F., Garcia-Pavia, P., Perrot, A., Christiaans, I., Salemink, S., Marcelis, C. L. M., Smeets, B. & 3 others, Brunner, H. G., Volders, P. G. A. & van den Wijngaard, A., 14 Jun 2016, In : European Heart Journal. 37, 23, p. 1815-1822

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Plasma cathepsin D correlates with histological classifications of fatty liver disease in adults and responds to intervention

Walenbergh, S. M. A., Houben, T., Rensen, S. S., Bieghs, V., Hendrikx, T., van Gorp, P. J., Oligschläger, Y., Jeurissen, M. L. J., Gijbels, M. J. J., Buurman, W. A., Vreugdenhil, A. C. E., Greve, J. W. M., Plat, J., Hofker, M. H., Kalhan, S., Pihlajamaki, J., Lindsey, P., Koek, G. H. & Shiri-Sverdlov, R., 6 Dec 2016, In : Scientific Reports. 6, 38278.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2015
9 Citations (Scopus)

Plasma cathepsin d levels: a novel tool to predict pediatric hepatic inflammation

Walenbergh, S. M., Houben, T., Hendrikx, T., Jeurissen, M. L. J., van Gorp, P. J., Vreugdenhil, A. C., Adriaanse, M., Buurman, W., Hofker, M., Mosca, A., Lindsey, P. J., Alisi, A., Liccardo, D., Panera, N., Koek, G. H., Nobili, V. & Shiri-Sverdlov, R., 1 Jan 2015, In : American Journal of Gastroenterology. 110, 3, p. 462-470

Research output: Contribution to journalArticleAcademicpeer-review

2014
12 Citations (Scopus)

Serotonergic reinforcement of intestinal barrier function is impaired in irritable bowel syndrome

Keszthelyi, D., Troost, F. J., Jonkers, D. M., van Eijk, H. M., Lindsey, P. J., Dekker, J., Buurman, W. & Masclee, A. A., Aug 2014, In : Alimentary Pharmacology & Therapeutics. 40, 4, p. 392-402 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

2013
28 Citations (Scopus)

A randomised controlled phase II trial of pre-operative celecoxib treatment reveals anti-tumour transcriptional response in primary breast cancer

Brandao, R. D., Veeck, J., Van de Vijver, K. K., Lindsey, P., de Vries, B., van Elssen, C. H., Blok, M. J., Keymeulen, K., Ayoubi, T., Smeets, H. J., Tjan-Heijnen, V. C. & Hupperets, P. S., 1 Jan 2013, In : Breast Cancer Research. 15, 2, p. R29

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Do genetic factors contribute to the relation between education and metabolic risk factors in young adults? A twin study

Vermeiren, A. P., Bosma, H., Gielen, M. J. F., Lindsey, P. J., Derom, C., Vlietinck, R., Loos, R. J. & Zeegers, M. P. A., Dec 2013, In : European Journal of Public Health. 23, 6, p. 986-991 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

2012
3 Citations (Scopus)

Alternative procedure to shorten rectal barostat procedure for the assessment of rectal compliance and visceral perception: a feasibility study.

Vanhoutvin, S. A., Troost, F. J., Kilkens, T. O. C., Lindsey, P. J., Jonkers, D. M. A. E., Venema, K., Masclee, A. A. M. & Brummer, R. J., 1 Jan 2012, In : Journal of Gastroenterology. 47, 8, p. 896-903

Research output: Contribution to journalArticleAcademicpeer-review

14 Citations (Scopus)

Does meal ingestion enhance sensitivity of visceroperception assessment in irritable bowel syndrome?

Ludidi, S., Conchillo, J. M., Keszthelyi, D., Koning, C. J. A., Vanhoutvin, S. A., Lindsey, P. J., Leufkens, A. M., Kruimel, J. W., Jonkers, D. M. A. E. & Masclee, A. A. M., 1 Jan 2012, In : Neurogastroenterology and Motility. 24, 1, p. 47-53 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Patient-derived fibroblasts indicate oxidative stress status and may justify antioxidant therapy in OXPHOS disorders

Voets, A. M., Lindsey, P. J., Vanherle, S. J. V., Timmer, E. D., Esseling, J. J., Koopman, W. J. H., Willems, P. H. G. M., Schoonderwoerd, G. C., De Groote, P., the Poll, B. T., de Coo, I. F. M. & Smeets, H. J. M., Nov 2012, In : Biochimica et Biophysica Acta-bioenergetics. 1817, 11, p. 1971-1978

Research output: Contribution to journalArticleAcademicpeer-review

35 Citations (Scopus)

Physical activity is the key determinant of skeletal muscle mitochondrial function in type 2 diabetes.

van Tienen, F. H. J., Praet, S. F., Feyter, H. M., van den Broek, N. M., Lindsey, P. J., Schoonderwoerd, K. G., Coo, I. F., Nicolay, K., Prompers, J. J., Smeets, H. J. M. & van Loon, L. J. C., Sep 2012, In : Journal of Clinical Endocrinology & Metabolism. 97, 9, p. 3261-3269 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)

Transcriptional changes in oxphos complex i deficiency are related to anti-oxidant pathways and could explain the disturbed calcium homeostasis

Voets, A. M., Huigsloot, M., Lindsey, P. J., Leenders, A. M., Koopman, W. J. H., Willems, P., Rodenburg, R. J., Smeitink, J. A. M. & Smeets, H. J. M., 1 Jan 2012, In : Biochimica et Biophysica Acta-Molecular Basis of Disease. 1822, 7, p. 1161-1168

Research output: Contribution to journalArticleAcademicpeer-review

2011
4 Citations (Scopus)

Arginine deficiency causes runting in the suckling period by selectively activating the stress kinase GCN2

Marion, V., Sankaranarayanan, S., de Theije, C. C., van Dijk, P. J., Lindsey, P. J., Lamers, M. C., Harding, H. P., Ron, D., Lamers, W. H. & Köhler, S. E., 18 Mar 2011, In : Journal of Biological Chemistry. 286, 11, p. 8866-8874 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

27 Citations (Scopus)
2010
9 Citations (Scopus)
2009
69 Citations (Scopus)

Butyrate-induced transcriptional changes in human colonic mucosa

Vanhoutvin, S. A., Troost, F. J., Hamer, H. M. H., Lindsey, P. J., Koek, G. H., Jonkers, D. M., Kodde, A., Venema, K. & Brummer, R. J., 1 Jan 2009, In : PLOS ONE. 4, 8, e6759.

Research output: Contribution to journalArticleAcademicpeer-review

60 Citations (Scopus)

The effects of butyrate enemas on visceral perception in healthy volunteers.

Vanhoutvin, S. A., Troost, F. J., Kilkens, T. O., Lindsey, P. J., Hamer, H. M. H., Jonkers, D. M., Venema, K. & Brummer, R. J. M., 1 Jan 2009, In : Neurogastroenterology and Motility. 21, 9, p. 952-e76

Research output: Contribution to journalArticleAcademicpeer-review

2008
9 Citations (Scopus)

Altered myocardial gene expression reveals possible maladaptive processes in heterozygous and homozygous cardiac myosin-binding protein C knockout mice.

Eijssen, L. M. T., van den Bosch, B. J. C., Vignier, N., Lindsey, P. J., van den Burg, C. M. M., Carrier, L., Doevendans, P. A. F. M., van der Vusse, G. J. & Smeets, H. J., 1 Jan 2008, In : Genomics. 91, 1, p. 52-60

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

A novel stepwise analysis procedure of genome-wide expression profiles identifies transcript signatures of thiamine genes as classifiers of mitochondrial mutants.

Eijssen, L. M. T., Lindsey, P. J., Peeters, R., Westra, R. L., van Eijsden, R. G. E., Bolotin-Fukuhara, M., Smeets, H. J. & Vlietinck, R. F. M., 1 Jan 2008, In : Yeast. 25, 2, p. 129-140

Research output: Contribution to journalArticleAcademicpeer-review

45 Citations (Scopus)

Identification of the transcriptional response of human intestinal mucosa to Lactobacillus plantarum WCFS1 in vivo

Troost, F. J., van Baarlen, P., Lindsey, P., Kodde, A., de Vos, W. M., Kleerebezem, M. & Brummer, R. J., 1 Jan 2008, In : BMC Genomics. 9, p. 374

Research output: Contribution to journalArticleAcademicpeer-review

25 Citations (Scopus)

Modeling genetic and environmental factors to increase heritability and ease the identification of candidate genes for birth weight: a twin study.

Gielen, M. J. F., Lindsey, P., Derom, C., Smeets, H. J., Souren, N. Y. P., Paulussen, A., Derom, R. & Nijhuis, J. G., 1 Jan 2008, In : Behavior Genetics. 38, 1, p. 44-54

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Scopus)

Termination of damaged protein repair defines the occurrence of symptoms in carriers of the m.3243A > G tRNA(Leu) mutation.

van Eijsden, R., Eijssen, L. M., Lindsey, P., van den Burg, C., de Wit, E., Rubio-Gozalbo, M. E., de Die-Smulders, C. E. M., Ayoubi, T., Sluiter, W., de Coo, I. & Smeets, H., 1 Jan 2008, In : Journal of Medical Genetics. 45, 8, p. 525-534

Research output: Contribution to journalArticleAcademicpeer-review

26 Citations (Scopus)

Twin-specific intrauterine 'growth' charts based on cross-sectional birthweight data.

Gielen, M., Lindsey, P. J., Derom, C., Loos, R. J. F., Souren, N. Y. P., Paulussen, A. D., Zeegers, M. P. A., Derom, R., Vlietinck, R. F. M. & Nijhuis, J. G., 1 Jan 2008, In : Twin Research and Human Genetics. 11, 2, p. 224-235

Research output: Contribution to journalArticleAcademicpeer-review

2007

Impact of two functional progesterone receptor polymorphisms (PRP): +331G/A and PROGINS on the cancer risks in familial breast/ovarian cancer

Romano, A., Baars, H., Martens, R. X., Brandao, R. D., Detisch, Y., Jongen, E., Blok, M. J., Lindsey, P. J., Fischer, D. C. & Gomez-Garcia, E. B., 1 Jan 2007, In : The Open Cancer Journal. 1, p. 1-8

Research output: Contribution to journalArticleAcademicpeer-review

13 Citations (Scopus)

Twin Birth Weight Standards

Gielen, M. J. F., Lindsey, P. J., Derom, C., Loos, R. J., Derom, R., Nijhuis, J. & Vlietinck, R., 1 Jan 2007, In : Neonatology. 92, 3, p. 164-173

Research output: Contribution to journalArticleAcademicpeer-review

2006
11 Citations (Scopus)

Curves of placental weights of live-born twins

Gielen, M. J. F., Lindsey, P. J., Derom, C., Loos, R. J., Derom, R., Nijhuis, J. G. & Vlietinck, R. F. M., 1 Jan 2006, In : Twin Research and Human Genetics. 9, 5, p. 664-672

Research output: Contribution to journalArticleAcademicpeer-review

29 Citations (Scopus)

Early and transient gene expression changes in pressure overload-induced cardiac hypertrophy in mice

van den Bosch, B. J., Lindsey, P. J., van den Burg, C. M., van Vlies, S. A., Lips, DJ., van der Vusse, G. J., Ayoubi, T. A. Y., Doevendans, P. A. F. M. & Smeets, H. J. M., 1 Jan 2006, In : Genomics. 88, 4, p. 480-8

Research output: Contribution to journalArticleAcademicpeer-review

15 Citations (Scopus)

Identification of TUB as a novel candidate gene influencing body weight in humans

Shiri-Sverdlov, R., Custers, A., van Vliet-Ostaptchouk, J. V., van Gorp, P. J. J., Lindsey, P. J., van Tilburg, J. H. O., Zhernakova, S., Feskens, E., van der A, D. L., Dolle, M. E., van Haeften, T. W., Koeleman, B. P., Hofker, M. H. & Wijmenga, C., 1 Jan 2006, In : Diabetes. 55, 2, p. 385-389

Research output: Contribution to journalArticleAcademicpeer-review

15 Citations (Scopus)

Multivariate distributions with correlation matrices for repeated measurements.

Lindsey, J. K. & Lindsey, P. J., 1 Jan 2006, In : Computational Statistics & Data Analysis. 50, 3, p. 720-732

Research output: Contribution to journalArticleAcademicpeer-review

32 Citations (Scopus)

Two functionally relevant polymorphisms in the human progesterone receptor gene (+331 G/A and progins) and the predisposition for breast and/or ovarian cancer

Romano, A., Lindsey, P. J., Fischer, D. C., Delvoux, B., Paulussen, A. D., Janssen, R. G. J. H. & Kieback, D. G., 1 Jan 2006, In : Gynecologic Oncology. 101, 2, p. 287-297

Research output: Contribution to journalArticleAcademicpeer-review

2005
36 Citations (Scopus)

Regional absence of mitochondria causing energy depletion in the myocardium of muscle LIM protein knockout mice

van den Bosch, B. J., van den Burg, C. M. M., Schoonderwoerd, K., Lindsey, P. J., Scholte, H. R., de Coo, R. F., van Rooij, E., Rockman, H. A., Doevendans, P. A. F. M. & Smeets, H. J., 1 Jan 2005, In : Cardiovascular Research. 65, 2, p. 411-418

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Scopus)

Up-regulation of CD36/FAT in preadipocytes in familial combined hyperlipidemia

Meex, S. J. R., van der Kallen, C. J. H., van Greevenbroek, M. M., Eurlings, P. M., El Hasnaoui, M. M., Evelo, C. T., Lindsey, P. J., Luiken, J. J. F. P., Glatz, J. F. & de Bruin, T. W., 1 Jan 2005, In : Faseb Journal. 19, 14, p. 2063-2065

Research output: Contribution to journalArticleAcademicpeer-review