TfamKnockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos

Auke B. C. Otten, Rick Kamps, Patrick Lindsey, Mike Gerards, Helene Pendeville-Samain, Marc Muller, Florence H. J. van Tienen, Hubert J. M. Smeets*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number381
Number of pages11
JournalFrontiers in Cell and Developmental Biology
Volume8
DOIs
Publication statusPublished - 12 Jun 2020

Keywords

  • mtDNA bottleneck
  • zebrafish embryogenesis
  • OXPHOS deficiency
  • transcriptomics
  • TFAM
  • mitochondria
  • MITOCHONDRIAL TRANSCRIPTION FACTOR
  • IN-VIVO
  • DNA
  • MUTATIONS
  • PROTEIN
  • PANTHER

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