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Research Output 2007 2019

  • 37 Article
  • 3 Comment/Letter to the editor
  • 2 Review article
  • 1 Doctoral Thesis

Incidence of cardiovascular disease in familial combined hyperlipidemia: A 15-year follow-up study

Luijten, J., van Greevenbroek, M. M. J., Schaper, N. C., Meex, S. J. R., van der Steen, C., Meijer, L. J., de Boer, D., de Graaf, J., Stehouwer, C. D. A. & Brouwers, M. C. G. J., Jan 2019, In : Atherosclerosis. 280, p. 1-6 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Movement disorders and nonmotor neuropsychological symptoms in children and adults with classical galactosemia

Kuiper, A., Grunewald, S., Murphy, E., Coenen, M. A., Eggink, H., Zutt, R., Rubio-Gozalbo, M. E., Bosch, A. M., Williams, M., Derks, T. G. J., Lachmann, R. H. L., Brouwers, M. C. G. J., Janssen, M. C. H., Tijssen, M. A. & de Koning, T. J., May 2019, In : Journal of Inherited Metabolic Disease. 42, 3, p. 451-458 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Patients With Aldolase B Deficiency Are Characterized by Increased Intrahepatic Triglyceride Content

Simons, N., Debray, F-G., Schaper, N. C., Kooi, M. E., Feskens, E. J. M., Hollak, C. E. M., Lindeboom, L., Koek, G. H., Bons, J. A. P., Lefeber, D. J., Hodson, L., Schalkwijk, C. G., Stehouwer, C. D. A., Cassiman, D. & Brouwers, M. C. G. J., Nov 2019, In : Journal of Clinical Endocrinology & Metabolism. 104, 11, p. 5053-5061 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Association of common gene variants in glucokinase regulatory protein with cardiorenal disease: A systematic review and meta-analysis

Simons, P. I. H. G., Simons, N., Stehouwer, C. D. A., Schalkwijk, C. G., Schaper, N. C. & Brouwers, M. C. G. J., 23 Oct 2018, In : PLOS ONE. 13, 10, 14 p., 0206174.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Non-alcoholic fatty liver disease concerns with glucokinase activators

Hodson, L. & Brouwers, M. C. G. J., 1 Sep 2018, In : The Lancet Diabetes & Endocrinology. 6, 9, p. 684-685 3 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

Risk of a first-ever acute myocardial infarction and all-cause mortality with sulphonylurea treatment: A population-based cohort study

van Dalem, J., Brouwers, M. C. G. J., Stehouwer, C. D. A., Krings, A., Klungel, O. H., Driessen, J. H. M., de Vries, F. & Burden, A. M., Apr 2018, In : Diabetes Obesity & Metabolism. 20, 4, p. 1056-1060 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The impact of metabolic control and tetrahydrobiopterin treatment on health related quality of life of patients with early-treated phenylketonuria: A PKU-COBESO study

Huijbregts, S. C. J., Bosch, A. M., Simons, Q. A., Jahja, R., Brouwers, M. C. G. J., De Sonneville, L. M. J., De Vries, M. C., Hofstede, F. C., Hollak, C. E. M., Janssen, M. C. H., Langendonk, J. G., Rubio-Gozalbo, M. E., Van der Meere, J. J., Van der Ploeg, A. T. & Van Spronsen, F. J., 1 Sep 2018, In : Molecular Genetics and Metabolism. 125, 1-2, p. 96-103 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

2017

Cardiovascular and metabolic effects of metformin in patients with type 1 diabetes (REMOVAL): a double-blind, randomised, placebo-controlled trial

Petrie, J. R., Chaturvedi, N., Ford, I., Brouwers, M. C. G. J., Greenlaw, N., Tillin, T., Hramiak, I., Hughes, A. D., Jenkins, A. J., Klein, B. E. K., Klein, R., Ooi, T. C., Rossing, P., Stehouwer, C. D. A., Sattar, N. & Colhoun, H. M., Aug 2017, In : The Lancet Diabetes & Endocrinology. 5, 8, p. 597-609 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Cognitive Profile and Mental Health in Adult Phenylketonuria: A PKU-COBESO Study

Jahja, R., van der Meere, J. J., Legemaat, A. M., Rubio-Gozalbo, M. E., Hofstede, F. C., van der Ploeg, A. T., Langendonk, J. G., Huijbregts, S. C. J., de Sonneville, L. M. J., Bosch, A. M., Hollak, C. E. M., Brouwers, M. C. G. J., de Vries, M. C., Janssen, M. C. H. & van Spronsen, F. J., May 2017, In : Neuropsychology. 31, 4, p. 437-447 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Long-Term Follow-Up of Cognition and Mental Health in Adult Phenylketonuria: A PKU-COBESO Study

Jahja, R., van Spronsen, F. J., de Sonneville, L. M. J., van der Meere, J. J., Bosch, A. M., Hollak, C. E. M., Rubio-Gozalbo, M. E., Brouwers, M. C. G. J., Hofstede, F. C., de Vries, M. C., Janssen, M. C. H., van der Ploeg, A. T., Langendonk, J. G. & Huijbregts, S. C. J., Sep 2017, In : Behavior Genetics. 47, 5, p. 486-497 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

PNPLA3, TM6SF2, and MBOAT7 Genotypes and Coronary Artery Disease

Simons, N., Isaacs, A., Koek, G. H., Kuc, S., Schaper, N. C. & Brouwers, M. C. G. J., Mar 2017, In : Gastroenterology. 152, 4, p. 912-913 2 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

Prognostic value of plasma lactate levels in a retrospective cohort presenting at a university hospital emergency department

van den Nouland, D. P. A., Brouwers, M. C. G. J. & Stassen, P. M., Jan 2017, In : BMJ Open. 7, 1, 9 p., 011450.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Propionic acidemia as a cause of adult-onset dilated cardiomyopathy

Riemersma, M., Hazebroek, M. R., Helderman-van den Enden, A. T. J. M., Salomons, G. S., Ferdinandusse, S., Brouwers, M. C. G. J., van der Ploeg, L., Heymans, S., Glatz, J. F. C., van den Wijngaard, A., Krapels, I. P. C., Bierau, J. & Brunner, H. G., Nov 2017, In : European Journal of Human Genetics. 25, 11, p. 1195-1201 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Het risico op hypoglykemieën bij sulfonylureumderivaten ten opzichte van metformine in relatie tot nierfunctie en metabolietgroep

van Dalem, J., Brouwers, M., Stehouwer, C., Krings, A., Leufkens, H. G. M., Driessen, J. H. M., de Vries, F. & Burden, A., 2016, In : Nederlands Platform voor Farmaceutisch Onderzoek. 1, a1636.

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Position statement on the role of healthcare professionals, patient organizations and industry in European Reference Networks

Hollak, C. E. M., Biegstraaten, M., Baumgartner, M. R., Belmatoug, N., Bembi, B., Bosch, A., Brouwers, M., Dekker, H., Dobbelaere, D., Engelen, M., Groenendijk, M. C., Lachmann, R., Langendonk, J. G., Langeveld, M., Linthorst, G., Morava, E., Poll-The, B. T., Rahman, S., Rubio Gozalbo, E., Spiekerkoetter, U. & 4 others, Treacy, E., Wanders, R., Zschocke, J. & Hagendijk, R., 25 Jan 2016, In : Orphanet Journal of Rare Diseases. 11, 7.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2 Citations (Scopus)

Risk of hypoglycaemia in users of sulphonylureas compared with metformin in relation to renal function and sulphonylurea metabolite group: population based cohort study

van Dalem, J., Brouwers, M. C. G. J., Stehouwer, C. D. A., Krings, A., Leufkens, H. G. M., Driessen, J. H. M., de Vries, F. & Burden, A. M., 13 Jul 2016, In : BMJ (e). 354, i3625.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
5 Citations (Scopus)

Social-cognitive functioning and social skills in patients with early treated phenylketonuria: a PKU-COBESO study

Jahja, R., van Spronsen, F. J., de Sonneville, L. M. J., van der Meere, J. J., Bosch, A. M., Hollak, C. E. M., Rubio Gozalbo, E., Brouwers, M. C. G. J., Hofstede, F. C., de Vries, M. C., Janssen, M. C. H., van der Ploeg, A. T., Langendonk, J. G. & Huijbregts, S. C. J., May 2016, In : Journal of Inherited Metabolic Disease. 39, 3, p. 355-362

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2015

Electrolyte and Acid-Base Disturbances in Diabetes Mellitus

Brouwers, M. C. G. J., 17 Dec 2015, In : New England Journal of Medicine. 373, 25, p. 2482-2482

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)

Elevated Lactate Levels in Patients With Poorly Regulated Type 1 Diabetes and Glycogenic Hepatopathy: A New Feature of Mauriac Syndrome

Brouwers, M. C. G. J., Ham, J. C., Wisse, E., Misra, S., Cleuren - Landewe, S., Rosenthal, M., Patel, D., Oliver, N., Bilo, H. J. G. & Murphy, E., Feb 2015, In : Diabetes Care. 38, 2, p. E11-E12

Research output: Contribution to journalArticleAcademicpeer-review

Is BRIEF a useful instrument in day to day care of patients with phenylketonuria?

Liemburg, G. B., Jahja, R., van Spronsen, F. J., de Sonneville, L. M. J., van der Meere, J. J., Bosch, A. M., Hollak, C. E. M., Rubio-Gozalbo, M. E., Brouwers, M. C. G. J., Hofstede, F. C., de Vries, M. C., Janssen, M. C. H., van der Ploeg, A. T., Langendonk, J. G. & Huijbregts, S. C. J., Mar 2015, In : Molecular Genetics and Metabolism. 114, 3, p. 425-430

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)

Modulation of Glucokinase Regulatory Protein: A Double-Edged Sword?

Brouwers, M. C. G. J., Jacobs, C., Bast, A., Stehouwer, C. D. A. & Schaper, N. C., 1 Jan 2015, In : Trends in Molecular Medicine. 21, 10, p. 583-594

Research output: Contribution to journalArticleAcademicpeer-review

2014
3 Citations (Scopus)
9 Citations (Scopus)

Familial combined hyperlipidemia: from molecular insights to tailored therapy

van Greevenbroek, M. M. J., Stalenhoef, A. F. H., de Graaf, J. & Brouwers, M. C. G. J., Jun 2014, In : Current Opinion in Lipidology. 25, 3, p. 176-182

Research output: Contribution to journalArticleAcademicpeer-review

2013

Mental health and social functioning in early treated Phenylketonuria: The PKU-COBESO study

Jahja, R., Huijbregts, S. C. J., de Sonneville, L. M. J., van der Meere, J. J., Bosch, A. M., Hollak, C. E. M., Rubio-Gozalbo, M. E., Brouwers, M. C. G. J., Hofstede, F. C., de Vries, M. C., Janssen, M. C. H., van der Ploeg, A. T., Langendonk, J. G. & van Spronsen, F. J., 2013, In : Molecular Genetics and Metabolism. 110, p. S57-S61

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Scopus)

Plasma proprotein convertase subtilisin kexin type 9 levels are related to markers of cholesterol synthesis in familial combined hyperlipidemia

Brouwers, M. C. G. J., Konrad, R. J., van Himbergen, T. M., Isaacs, A., Otokozawa, S., Troutt, J. S., Schaefer, E. J., van Greevenbroek, M. M. J., Stalenhoef, A. F. H. & de Graaf, J., Nov 2013, In : Nutrition Metabolism and Cardiovascular Diseases. 23, 11, p. 1115-1121

Research output: Contribution to journalArticleAcademicpeer-review

2012
7 Citations (Scopus)

Metformin-associated lactic acidosis in a patient with normal kidney function.

van Sloten, T. T., Pijpers, E., Stehouwer, C. D. A. & Brouwers, M. C., Jun 2012, In : Diabetes Research and Clinical Practice. 96, 3, p. E57-E58 2 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

The genetics of familial combined hyperlipidaemia

Brouwers, M. C. G. J., van Greevenbroek, M. M. J., Stehouwer, C. D. A., de Graaf, J. & Stalenhoef, A. F. H., Jun 2012, In : Nature Reviews Endocrinology. 8, 6, p. 352-362

Research output: Contribution to journalArticleAcademicpeer-review

2011
10 Citations (Scopus)

Plasma proprotein convertase subtilisin kexin type 9 is a heritable trait of familial combined hyperlipidemia

Brouwers, M. C., van Greevenbroek, M. M. J., Troutt, J., Bonner Freeman, A., Lu, A., Schaper, N. C., Konrad, R. J. & Stehouwer, C. D. A., 1 Jan 2011, In : Clinical Science. 121, p. 397-403

Research output: Contribution to journalArticleAcademicpeer-review

15 Citations (Scopus)

Novel drugs in familial combined hyperlipidemia: lessons from type 2 diabetes mellitus.

Brouwers, M. C., de Graaf, J., van Greevenbroek, M. M. J., Schaper, N. C., Stehouwer, C. D. A. & Stalenhoef, A. F., 1 Jan 2010, In : Current Opinion in Lipidology. 21, 6, p. 530-538

Research output: Contribution to journalArticleAcademicpeer-review

2009
17 Citations (Scopus)

Increased arterial stiffness in familial combined hyperlipidemia

Brouwers, M. C., Reesink, K. D., van Greevenbroek, M. M., Meinders, J. M., van der Kallen, C. J., Schaper, N., Hoeks, A. P. & Stehouwer, C. D., 1 Jan 2009, In : Journal of Hypertension. 27, 5, p. 1009-16

Research output: Contribution to journalArticleAcademicpeer-review

2008
358 Downloads (Pure)

Hepatic steatosis in familial combined hyperlipidemia

Brouwers, M. C. G. J., 1 Jan 2008, Maastricht: Universiteit Maastricht. 165 p.

Research output: ThesisDoctoral ThesisInternal

Open Access
File
1 Citation (Scopus)
2007
48 Citations (Scopus)