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  • A characterization of cis- and trans-heritability of RNA-Seq-based gene expression

    Ouwens, K. G., Jansen, R., Nivard, M. G., van Dongen, J., Frieser, M. J., Hottenga, J-J., Arindrarto, W., Claringbould, A., van Iterson, M., Mei, H., Franke, L., Heijmans, B. T., 't Hoen, P. A. C., van Meurs, J., Brooks, A., Penninx, B. W. J. H., Boomsma, D., Isaacs, A., Pool, R., Hottenga, J. J. & 31 others, van Greevenbroek, M. M. J., Stehouwer, C. D. A., van der Kallen, C. J. H., Schalkwijk, C. G., Wijmenga, C., Zhernakova, S., Tigchelaar, E. F., Slagboom, P. E., Beekman, M., Deelen, J., van Heemst, D., Veldink, J. H., van den Berg, L. H., van Duijn, C. M., Hofman, B. A., Uitterlinden, A. G., Jhamai, P. M., Verbiest, M., Suchiman, H. E. D., Verkerk, M., van der Breggen, R., van Rooij, J., Lakenberg, N., van Galen, M., Bot, J., Zhernakova, D., van't Hof, P., Deelen, P., Nooren, I., Moed, M. & BIOS Consortium, Feb 2020, In: European Journal of Human Genetics. 28, 2, p. 253-263 11 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  • JavaCyte, a novel open-source tool for automated quantification of key hallmarks of cardiac structural remodeling

    Winters, J., von Braunmuhl, M. E., Zeemering, S., Gilbers, M., Ten Brink, T., Scaf, B., Guasch, E., Mont, L., Batlle, M., Sinner, M., Hatem, S., Mansour, M. K., Fabritz, L., Sommerfeld, L. C., Kirchhof, P., Isaacs, A., Stoll, M., Schotten, U. & Verheule, S., 18 Nov 2020, In: Scientific Reports. 10, 1, 15 p., 20074.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
  • Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

    Ntalla, I., Weng, L-C., Cartwright, J. H., Hall, A. W., Sveinbjornsson, G., Tucker, N. R., Choi, S. H., Chaffin, M. D., Roselli, C., Barnes, M. R., Mifsud, B., Warren, H. R., Hayward, C., Marten, J., Cranley, J. J., Concas, M. P., Gasparini, P., Boutin, T., Kolcic, I., Polasek, O. & 167 others, Rudan, I., Araujo, N. M., Lima-Costa, M. F., Ribeiro, A. L. P., Souza, R. P., Tarazona-Santos, E., Giedraitis, V., Ingelsson, E., Mahajan, A., Morris, A. P., Del Greco, F. M., Foco, L., Gogele, M., Hicks, A. A., Cook, J. P., Lind, L., Lindgren, C. M., Sundstrom, J., Nelson, C. P., Riaz, M. B., Samani, N. J., Sinagra, G., Ulivi, S., Kahonen, M., Mishra, P. P., Mononen, N., Nikus, K., Caulfield, M. J., Dominiczak, A., Padmanabhan, S., Montasser, M. E., O'Connell, J. R., Ryan, K., Shuldiner, A. R., Aeschbacher, S., Conen, D., Risch, L., Theriault, S., Hutri-Kahonen, N., Lehtimaki, T., Lyytikainen, L-P., Raitakari, O. T., Barnes, C. L. K., Campbell, H., Joshi, P. K., Wilson, J. F., Isaacs, A., Kors, J. A., van Duijn, C. M., Huang, P. L., Gudnason, V., Harris, T. B., Launer, L. J., Smith, A., Bottinger, E. P., Loos, R. J. F., Nadkarni, G. N., Preuss, M. H., Correa, A., Mei, H., Wilson, J., Meitinger, T., Mueller-Nurasyid, M., Peters, A., Waldenberger, M., Mangino, M., Spector, T. D., Rienstra, M., van de Vegte, Y. J., van der Harst, P., Verweij, N., Kaab, S., Schramm, K., Sinner, M. F., Strauch, K., Cutler, M. J., Fatkin, D., London, B., Olesen, M., Roden, D. M., Shoemaker, M. B., Smith, J. G., Biggs, M. L., Bis, J. C., Brody, J. A., Psaty, B. M., Rice, K., Sotoodehnia, N., De Grandi, A., Fuchsberger, C., Pattaro, C., Pramstaller, P. P., Ford, I., Jukema, J. W., Macfarlane, P. W., Trompet, S., Doerr, M., Felix, S. B., Voelker, U., Weiss, S., Havulinna, A. S., Jula, A., Saaksjarvi, K., Salomaa, V., Guo, X., Heckbert, S. R., Lin, H. J., Rotter, J., Taylor, K. D., Yao, J., de Mutsert, R., Maan, A. C., Mook-Kanamori, D. O., Noordam, R., Cucca, F., Ding, J., Lakatta, E. G., Qian, Y., Tarasov, K., Levy, D., Lin, H., Newton-Cheh, C. H., Lunetta, K. L., Murray, A. D., Porteous, D. J., Smith, B. H., Stricker, B. H., Uitterlinden, A., van den Berg, M. E., Haessler, J., Jackson, R. D., Kooperberg, C., Peters, U., Reiner, A. P., Whitsel, E. A., Alonso, A., Arking, D. E., Boerwinkle, E., Ehret, G. B., Soliman, E. Z., Avery, C. L., Gogarten, S. M., Kerr, K. F., Laurie, C. C., Seyerle, A. A., Stilp, A., Assa, S., Said, M. A., van der Ende, M. Y., Lambiase, P. D., Orini, M., Ramirez, J., Van Duijvenboden, S., Arnar, D. O., Gudbjartsson, D. F., Holm, H., Sulem, P., Thorleifsson, G., Thorolfsdottir, R. B., Thorsteinsdottir, U., Benjamin, E. J., Tinker, A., Stefansson, K., Ellinor, P. T., Jamshidi, Y., Lubitz, S. A. & Munroe, P. B., 21 May 2020, In: Nature Communications. 11, 1, 12 p., 2542.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
  • Non-alcoholic fatty liver disease and cardiovascular disease: assessing the evidence for causality

    Brouwers, M. C. G. J., Simons, N., Stehouwer, C. D. A. & Isaacs, A., Feb 2020, In: Diabetologia. 63, 2, p. 253-260 8 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
  • An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis

    Liu, J., Carnero-Montoro, E., van Dongen, J., Lent, S., Nedeljkovic, I., Ligthart, S., Tsai, P-C., Martin, T. C., Mandaviya, P. R., Jansen, R., Peters, M. J., Duijts, L., Jaddoe, V. W. V., Tiemeier, H., Felix, J. F., Willemsen, G., de Geus, E. J. C., Chu, A. Y., Levy, D., Hwang, S-J. & 37 others, Bressler, J., Gondalia, R., Salfati, E. L., Herder, C., Hidalgo, B. A., Tanaka, T., Moore, A. Z., Lemaitre, R. N., Jhun, M. A., Smith, J. A., Sotoodehnia, N., Bandinelli, S., Ferrucci, L., Arnett, D. K., Grallert, H., Assimes, T. L., Hou, L., Baccarelli, A., Whitsel, E. A., van Dijk, K. W., Amin, N., Uitterlinden, A. G., Sijbrands, E. J. G., Franco, O. H., Dehghan, A., Spector, T. D., Dupuis, J., Hivert, M-F., Rotter, J., Meigs, J. B., Pankow, J. S., van Meurs, J. B. J., Isaacs, A., Boomsma, D., Bell, J. T., Demirkan, A. & van Duijn, C. M., 13 Jun 2019, In: Nature Communications. 10, 11 p., 2581.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
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