20052020

Research output per year

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Article
2020

Mephedrone and Alcohol Interactions in Humans

Papaseit, E., Pérez-Mañá, C., de Sousa Fernandes Perna, E. B., Olesti, E., Mateus, J., Kuypers, K. P. C., Theunissen, E. L., Fonseca, F., Torrens, M., Ramaekers, J. G., de la Torre, R. & Farré, M., 28 Jan 2020, In : Frontiers in Pharmacology. 10, 17 p., 1588.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2019
Open Access
Open Access

Cocaine enhances figural, but impairs verbal 'flexible' divergent thinking

Hutten, N. R. P. W., Steenbergen, L., Colzato, L. S., Hommel, B., Theunissen, E. L., Ramaekers, J. G. & Kuypers, K. P. C., Jul 2019, In : European Neuropsychopharmacology. 29, 7, p. 813-824 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Motives and Side-Effects of Microdosing With Psychedelics Among Users

Hutten, N. R. P. W., Mason, N. L., Dolder, P. C. & Kuypers, K. P. C., Jul 2019, In : International Journal of Neuropsychopharmacology. 22, 7, p. 426-434 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Pharmacokinetic properties of 4-fluoroamphetamine in serum and oral fluid after oral ingestion

Toennes, S. W., Schneider, D., Pogoda, W., Paulke, A., Wunder, C., Theunissen, E. L., Kuypers, K. P. C., de Sousa Fernandes Perna, E. & Ramaekers, J. G., Jul 2019, In : Drug Testing and Analysis. 11, 7, p. 1028-1034 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Psychedelic medicine: The biology underlying the persisting psychedelic effects

Kuypers, K. P. C., Apr 2019, In : Medical Hypotheses. 125, p. 21-24 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Self-Rated Effectiveness of Microdosing With Psychedelics for Mental and Physical Health Problems Among Microdosers

Hutten, N. R. P. W., Mason, N. L., Dolder, P. C. & Kuypers, K. P. C., 13 Sep 2019, In : Frontiers in Psychiatry. 10, 9 p., 672.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Sub-Acute Effects of Psilocybin on Empathy, Creative Thinking, and Subjective Well-Being

Mason, N. L., Mischler, E., Uthaug, M. & Kuypers, K. P. C., 2019, In : Journal of Psychoactive Drugs. 51, 2, p. 123-134 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2018

A single dose of cocaine enhances prospective memory performance

Hutten, N. RPW., Kuypers, K. PC., van Wel, J. HP., Theunissen, E. L., Toennes, S. W., Verkes, R-J. & Ramaekers, J. G., Aug 2018, In : Journal of Psychopharmacology. 32, 8, p. 883–892 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Depressive mood ratings are reduced by MDMA in female polydrug ecstasy users homozygous for the l-allele of the serotonin transporter

Kuypers, K. P. C., de la Torre, R., Farre, M., Xicota, L., Perna, E. B. D. S. F., Theunissen, E. L. & Ramaekers, J. G., 18 Jan 2018, In : Scientific Reports. 8, 7 p., 1061.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Drug liking and wanting, not impulsive action or reflection is increased by 4-fluoroamphetamine

Kuypers, K. P. C., de Sousa Fernandes Perna, E. B., Dolder, P. C., Toennes, S. W., Theunissen, E. L., Mason, N. L., Hutten, N. R. P. W. & Ramaekers, J. G., Aug 2018, In : Psychopharmacology. 235, 8, p. 2349-2356 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

MDMA-induced indifference to negative sounds is mediated by the 5-HT2A receptor

Kuypers, K. P. C., de la Torre, R., Farre, M., Pizarro, N., Xicota, L. & Ramaekers, J. G., Feb 2018, In : Psychopharmacology. 235, 2, p. 481-490 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Out of the box: A psychedelic model to study the creative mind

Kuypers, K. P. C., Jun 2018, In : Medical Hypotheses. 115, p. 13-16 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Peripheral endocannabinoid concentrations are not associated with verbal memory impairment during MDMA intoxication

Haijen, E., Farre, M., de la Torre, R., Pastor, A. M., Olesti, E., Pizarro, N., Ramaekers, J. G. & Kuypers, K. P. C., Mar 2018, In : Psychopharmacology. 235, 3, p. 709-717 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access

Sub-acute and long-term effects of ayahuasca on affect and cognitive thinking style and their association with ego dissolution

Uthaug, M. V., van Oorsouw, K., Kuypers, K. P. C., van Boxtel, M., Broers, N. J., Mason, N. L., Toennes, S. W., Riba, J. & Ramaekers, J. G., Oct 2018, In : Psychopharmacology. 235, 10, p. 2979–2989 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Brain reactivity to alcohol and cannabis marketing during sobriety and intoxication

de Sousa Fernandes Perna, E. B., Theunissen, E. L., Kuypers, K. P. C., Evers, E. A., Stiers, P., Toennes, S. W., Witteman, J., van Dalen, W. & Ramaekers, J. G., May 2017, In : Addiction Biology. 22, 3, p. 823–832 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Emotional empathic responses to dynamic negative affective stimuli is gender-dependent

Kuypers, K. P. C., 31 Aug 2017, In : Frontiers in Psychology. 8, 1491.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

MDMA-induced dissociative state not mediated by the 5-HT2A receptor

Puxty, D. J., Ramaekers, J. G., de la Torre, R., Farré, M., Pizarro, N., Pujadas, M. & Kuypers, K. P. C., 11 Jul 2017, In : Frontiers in Pharmacology. 8, 9 p., 455.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Multifaceted empathy of healthy volunteers after single doses of MDMA: A pooled sample of placebo-controlled studies

Kuypers, K. P., Dolder, P. C., Ramaekers, J. G. & Liechti, M. E., May 2017, In : Journal of Psychopharmacology. 31, 5, p. 589–598 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2016

Ayahuasca enhances creative divergent thinking while decreasing conventional convergent thinking

Kuypers, K. P. C., Riba, J., de la Fuente Revenga, M., Barker, S., Theunissen, E. L. & Ramaekers, J. G., Sep 2016, In : Psychopharmacology. 233, 18, p. 3395–3403 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
1 Citation (Scopus)
180 Downloads (Pure)

Cannabis and tolerance: acute drug impairment as a function of cannabis use history

Ramaekers, J. G., van Wel, J. H., Spronk, D. B., Toennes, S. W., Kuypers, K. P. C., Theunissen, E. L. & Verkes, R. J., 26 May 2016, In : Scientific Reports. 6, 8 p., 26843.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
2 Citations (Scopus)
169 Downloads (Pure)

Neurocognitive performance following acute mephedrone administration, with and without alcohol

de Sousa Fernandes Perna, E. B., Papaseit, E., Pérez-Mañá, C., Mateus, J., Theunissen, E. L., Kuypers, K. P. C., de la Torre, R., Farré, M. & Ramaekers, J. G., Dec 2016, In : Journal of Psychopharmacology. 30, 12, p. 1305–1312 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Subjective aggression during alcohol and cannabis intoxication before and after aggression exposure

De Sousa Fernandes Perna, E. B., Theunissen, E. L., Kuypers, K. P. C., Toennes, S. W. & Ramaekers, J. G., Sep 2016, In : Psychopharmacology. 233, 18, p. 3331–3340 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
2 Citations (Scopus)
159 Downloads (Pure)

Verbal memory impairment in polydrug ecstasy users: A clinical perspective

Kuypers, K. P. C., Theunissen, E. L., van Wel, J. H. P., de Sousa, E. B., Perna, F., Linssen, A., Sambeth, A., Schultz, B. G. & Ramaekers, J. G., 23 Feb 2016, In : PLOS ONE. 11, 2, 0149438.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
1 Citation (Scopus)
152 Downloads (Pure)
2015

Cannabis and cocaine decrease cognitive impulse control and functional corticostriatal connectivity in drug users with low activity DBH genotypes

Ramaekers, J. G., van Wel, J. H., Spronk, D., Franke, B., Kenis, G., Toennes, S. W., Kuypers, K. P. C., Theunissen, E. L., Stiers, P. & Verkes, R. J., 14 Dec 2015, In : Brain Imaging and Behavior. p. 1254–1263

Research output: Contribution to journalArticleAcademicpeer-review

Changes in serotonin transporter (5-HTT) gene expression in peripheral blood cells after MDMA intake

Yubero-Lahoz, S., Kuypers, K. P. C., Ramaekers, J. G., Langohr, K., Farre, M. & de la Torre, R., Jun 2015, In : Psychopharmacology. 232, 11, p. 1921-1929

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

MDMA, cannabis, and cocaine produce acute dissociative symptoms

van Heugten-Van der Kloet, D., Giesbrecht, T., van Wel, J., Bosker, W. M., Kuypers, K. P. C., Theunissen, E. L., Spronk, D. B., Verkes, R. J., Merckelbach, H. & Ramaekers, J. G., 30 Aug 2015, In : Psychiatry Research. 228, 3, p. 907-912 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Psychedelic symptoms of cannabis and cocaine use as a function of trait impulsivity

van Wel, J. H. P., Spronk, D. B., Kuypers, K. P. C., Theunissen, E. L., Toennes, S. W., Verkes, R. J. & Ramaekers, J. G., 1 Mar 2015, In : Journal of Psychopharmacology. 29, 3, p. 324-334 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Rivastigmine but not vardenafil reverses cannabis-induced impairment of verbal memory in healthy humans

Theunissen, E. L., Heckman, P., de Sousa Fernandes Perna, E. B., Kuypers, K. P. C., Sambeth, A., Blokland, A., Prickaerts, J., Toennes, S. W. & Ramaekers, J. G., 1 Jan 2015, In : Psychopharmacology. 232, 2, p. 343-353 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)
2014

Memory and mood during MDMA intoxication, with and without memantine pretreatment

de Sousa Fernandes Perna, E. B., Theunissen, E. L., Kuypers, K. P. C., Heckman, P., de la Torre, R., Farre, M. & Ramaekers, J. G., Dec 2014, In : Neuropharmacology. 87, p. 198-205 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)

No evidence that MDMA-induced enhancement of emotional empathy is related to peripheral oxytocin levels or 5-HT1a receptor activation

Kuypers, K. P. C., de la Torre, R., Farre, M., Yubero-Lahoz, S., Dziobek, I., Bos, W. & Ramaekers, J. G., 27 Jun 2014, In : PLOS ONE. 9, 6, 14 p., e100719.

Research output: Contribution to journalArticleAcademicpeer-review

19 Citations (Scopus)
2013

Escitalopram Decreases Cross-Regional Functional Connectivity within the Default-Mode Network

van de Ven, V., Wingen, M., Kuypers, K. P. C., Ramaekers, J. G. & Formisano, E., 27 Jun 2013, In : PLOS ONE. 8, 6, 10 p., 68355.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
16 Citations (Scopus)

Inhibition of MDMA-induced increase in cortisol does not prevent acute impairment of verbal memory

Kuypers, K. P. C., de la Torre, R., Farre, M., Pujadas, M. & Ramaekers, J. G., 1 Jan 2013, In : British Journal of Pharmacology. 168, 3, p. 607-617

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Methylphenidate reduces functional connectivity of nucleus accumbens in brain reward circuit

Ramaekers, J. G., Evers, E. A., Theunissen, E. L., Kuypers, K. P. C., Goulas, A. & Stiers, P., Sep 2013, In : Psychopharmacology. 229, 2, p. 219-226 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

15 Citations (Scopus)

Psychomotor function in chronic daily Cannabis smokers during sustained abstinence

Bosker, W. M., Karschner, E. L., Lee, D., Goodwin, R. S., Hirvonen, J., Innis, R. B., Theunissen, E. L., Kuypers, K. P. C., Huestis, M. A. & Ramaekers, J. G., 2 Jan 2013, In : PLOS ONE. 8, 1, 7 p., 53127.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
25 Citations (Scopus)

Single doses of THC and cocaine decrease proficiency of impulse control in heavy cannabis users

van Wel, J. H. P., Kuypers, K. P. C., Theunissen, E. L., Toennes, S. W., Spronk, D. B., Verkes, R. J. & Ramaekers, J. G., Dec 2013, In : British Journal of Pharmacology. 170, 7, p. 1410-1420 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Scopus)
2012

A case-control study estimating accident risk for alcohol, medicines and illegal drugs

Kuypers, K. P. C., Legrand, S. A., Ramaekers, J. G. & Verstraete, A. G., 28 Aug 2012, In : PLOS ONE. 7, 8, 9 p., e43496.

Research output: Contribution to journalArticleAcademicpeer-review

36 Citations (Scopus)

A placebo-controlled study to assess Standardized Field Sobriety Tests performance during alcohol and cannabis intoxication in heavy cannabis users and accuracy of point of collection testing devices for detecting THC in oral fluid

Bosker, W. M., Theunissen, E. L., Conen, S., Kuypers, K. P. C., Jeffery, W. K., Walls, H. C., Kauert, G. F., Toennes, S. W., Moeller, M. R. & Ramaekers, J. G., Oct 2012, In : Psychopharmacology. 223, 4, p. 439-446 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

19 Citations (Scopus)

Effects of acute MDMA intoxication on mood and impulsivity: role of the 5-HT(2) and 5-HT(1) receptors

van Wel, J. H. P., Kuypers, K. P. C., Theunissen, E. L., Bosker, W. M., Bakker, K. & Ramaekers, J. G., 10 Jul 2012, In : PLOS ONE. 7, 7, 8 p., 40187.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
20 Citations (Scopus)

Effects of stimulant drugs on actual and simulated driving: perspectives from four experimental studies conducted as part of the DRUID research consortium.

Ramaekers, J. G., Kuypers, K. P. C., Bosker, W. M., Brookhuis, K. A., Veldstra, J. A., Simons, R., Martens, M., Hjalmdahl, M., Forsman, A. & Knoche, A., 1 Jan 2012, In : Psychopharmacology. 222, 3, p. 413-418

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

MDMA (ecstasy) effects on actual driving performance before and after sleep deprivation, as function of dose and concentration in blood and oral fluid

Bosker, W. M., Kuypers, K. P. C., Conen, S., Kauert, G. F., Toennes, S. W., Skopp, G. & Ramaekers, J. G., Aug 2012, In : Psychopharmacology. 222, 3, p. 367-376 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

10 Citations (Scopus)

Medicinal Delta(9)-tetrahydrocannabinol (dronabinol) impairs on-the-road driving performance of occasional and heavy cannabis users but is not detected in Standard Field Sobriety Tests

Bosker, W. M., Kuypers, K. P. C., Theunissen, E. L., Surinx, A., Blankespoor, R. J., Skopp, G., Jeffery, W. K., Walls, H. C., van Leeuwen, C. J. & Ramaekers, J. G., Oct 2012, In : Addiction. 107, 10, p. 1837-1844 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

18 Citations (Scopus)
2011

Blockade of 5-HT(2) receptor selectively prevents MDMA-induced verbal memory impairment

van Wel, J. H. P., Kuypers, K. P. C., Theunissen, E. L., Bosker, W. M., Bakker, K. & Ramaekers, J. G., 1 Jan 2011, In : Neuropsychopharmacology. 36, 9, p. 1932-1939

Research output: Contribution to journalArticleAcademicpeer-review

14 Citations (Scopus)