Erik Biessen

2025

Inhibition of intracellular versus extracellular cathepsin D differentially alters the liver lipidome of mice with metabolic dysfunction-associated steatohepatitis

Vermeulen, I., Li, M., van Mourik, H., Yadati, T., Eijkel, G., Balluff, B., Godschalk, R., Temmerman, L., Biessen, E. A. L., Kulkarni, A., Theys, J., Houben, T., Cillero-Pastor, B. & Shiri-Sverdlov, R., Apr 2025, In: FEBS Journal. 292, 7, p. 1781-1797 17 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

MicroRNA-26b protects against MASH development in mice and can be efficiently targeted with lipid nanoparticles

Peters, L., Rakateli, L., Huchzermeier, R., Bonnin-Marquez, A., Maas, S. L., Lin, C., Jans, A., Geng, Y., Gorter, A., Gijbels, M., Rensen, S., Olinga, P., Hendrikx, T., Krawczyk, M., Brisbois, M., Jankowski, J., Bidzhekov, K., Weber, C., Biessen, E. A. L. & Shiri-Sverdlov, R. & 4 others, Houben, T., Doering, Y., Bartneck, M. & van der Vorst, E., 22 Apr 2025, In: Elife. 13, 22 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Protein carbamylation in atherosclerotic plaques correlates with uremia and disease progression, localizing predominantly to foam cells

Saar-Kovrov, V., Pawlowska, A., Guillot, A., Gijbels, M. J. J., Sluimer, J. C., Temmerman, L., Goossens, P., Mees, B. M. E., Tacke, F., Jankowski, V., Jankowski, J., Donners, M. M. P. C. & Biessen, E. A. L., 28 May 2025, In: Frontiers in Immunology. 16, 15 p., 1532250.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

The significance of PAX5 in Merkel cell carcinoma

Chteinberg, E., Kolarova, J., Vogt, J., Macamo, A., Bormann, F., Kretzmer, H., Speel, E. J., van den Oord, J., Schneider, C., Stilgenbauer, S., Becker, J. C., Winnepenninckx, V., Biessen, E., Zenke, M., Kurz, A. K., Siebert, R. & zur Hausen, A., May 2025, In: Journal of Pathology. 266, 1, p. 81-94 14 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

2024

CCL18 aggravates atherosclerosis by inducing CCR6-dependent T-cell influx and polarization

Singh, A., Kraaijeveld, A. O., Curaj, A., Wichapong, K., Hammerich, L., de Jager, S. C. A., Bot, I., Atamas, S. P., van Berkel, T. J. C., Jukema, J. W., Comerford, I., Mccoll, S. R., Mees, B., Heemskerk, J. W. M., Nicolaes, G. A. F., Hackeng, T., Liehn, E. A., Tacke, F. & Biessen, E. A. L., 13 May 2024, In: Frontiers in Immunology. 15, 15 p., 1327051.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Colony stimulating factor 1 receptor (Csf1r) expressing cell ablation in mafia (macrophage-specific Fas-induced apoptosis) mice alters monocyte landscape and atherosclerotic lesion characteristics

Medina, I., Wieland, E. B., Temmerman, L., Otten, J. J. T., Bermudez, B., Bot, I., Rademakers, T., Wijnands, E., Schurgers, L., Mees, B., van Berkel, T. J. C., Goossens, P. & Biessen, E. A. L., Nov 2024, In: European Journal of Immunology. 54, 11, 2350943.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Genome-scale metabolic network of human carotid plaque reveals the pivotal role of glutamine/glutamate metabolism in macrophage modulating plaque inflammation and vulnerability

Jin, H., Zhang, C., Nagenborg, J., Juhasz, P., Ruder, A. V., Sikkink, C. J. J. M., Mees, B. M. E., Waring, O., Sluimer, J. C., Neumann, D., Goossens, P., Donners, M. M. P. C., Mardinoglu, A. & Biessen, E. A. L., 8 Jul 2024, In: Cardiovascular Diabetology. 23, 1, 240.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Human atherosclerotic plaque transcriptomics reveals endothelial beta-2 spectrin as a potential regulator a leaky plaque microvasculature phenotype

Rademakers, T., Manca, M., Jin, H., Orban, T., Perisic, L. M., Frissen, H. J. M., Rühle, F., Hautvast, P., van Rijssel, J., van Kuijk, K., Mees, B. M. E., Peutz-Kootstra, C. J., Heeneman, S., Daemen, M. J. A. P., Pasterkamp, G., Stoll, M., van Zandvoort, M. A. M. J., Hedin, U., Dequiedt, F. & van Buul, J. D. & 2 others, Sluimer, J. C. & Biessen, E. A. L., Aug 2024, In: Angiogenesis. 27, 3, p. 461-474 14 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Identification of a gene network driving the attenuated response to lipopolysaccharide of monocytes from hypertensive coronary artery disease patients

Lu, C., Donners, M. M. P. C., de Baaij, J. B. J., Jin, H., Otten, J. J. T., Manca, M., van Zonneveld, A. J., Jukema, J. W., Kraaijeveld, A., Kuiper, J., Pasterkamp, G., Mees, B., Sluimer, J. C., Cavill, R., Karel, J. M. H., Goossens, P. & Biessen, E. A. L., 12 Feb 2024, In: Frontiers in Immunology. 15, 13 p., 1286382.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Increased levels of a mycophenolic acid metabolite in patients with kidney failure negatively affect cardiomyocyte health

Harlacher, E., Schulte, C., Vondenhoff, S., Schmitt-Kopplin, P., Diederich, P., Hemmers, C., Moellmann, J., Wollenhaupt, J., Veltrop, R., Biessen, E., Lehrke, M., Peters, B., Schlieper, G., Kuppe, C., Floege, J., Jankowski, V., Marx, N., Jankowski, J. & Noels, H., 6 Mar 2024, In: Frontiers in Cardiovascular Medicine. 11, 11 p., 1346475.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

In situ lipid-loading activates peripheral dendritic cell subsets characterized by cellular ROS accumulation but compromises their capacity to prime naïve T cells

Christ, A., Maas, S. L., Jin, H., Lu, C., Legein, B., Wijnands, E., Temmerman, L., Otten, J., Isaacs, A., Zenke, M., Stoll, M., Biessen, E. A. L. & van der Vorst, E. P. C., 5 Jan 2024, In: Free Radical Biology and Medicine. 210, p. 406-415 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Macrophage heterogeneity in atherosclerosis: A matter of context

Wieland, E. B., Kempen, L. J., Donners, M. M., Biessen, E. A. & Goossens, P., Jan 2024, In: European journal of immunology. 54, 1, 9 p., 2350464.

Research output: Contribution to journal › (Systematic) Review article › peer-review

Open Access

The calcium-sensing-receptor (CaSR) in adipocytes contributes to sex-differences in the susceptibility to high fat diet induced obesity and atherosclerosis

Adam, S., Maas, S. L., Huchzermeier, R., Rakateli, L., Abschlag, K., Hohl, M., Liao, L., Bartneck, M., Teunissen, M., Wouters, K., Santovito, D., Jankowski, J., Biessen, E. A. L. & van der Vorst, E. P. C., 1 Sept 2024, In: EBioMedicine. 107, 16 p., 105293.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

2023

Amlodipine limits microglia activation and cognitive dysfunction in aged hypertensive mice

Kerkhofs, D., Helgers, R., Hermes, D., Steinbusch, H. P. J., Van Essen, H., Leenders, P., Prickaerts, J., Staals, J., Biessen, E. A., Van Oostenbrugge, R. J. & Foulquier, S., 1 Jul 2023, In: Journal of Hypertension. 41, 7, p. 1159-1167 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Blood Milieu in Acute Myocardial Infarction Reprograms Human Macrophages for Trauma Repair

Fontaine, M. A. C., Jin, H., Gagliardi, M., Rousch, M., Wijnands, E., Stoll, M., Li, X., Schurgers, L., Reutelingsperger, C., Schalkwijk, C., van den Akker, N. M. S., Molin, D. G. M., Gullestad, L., Eritsland, J., Hoffman, P., Skjelland, M., Andersen, G. Ø., Aukrust, P., Karel, J. & Smirnov, E. & 3 others, Halvorsen, B., Temmerman, L. & Biessen, E. A. L., 14 Feb 2023, In: Advanced Science. 10, 5, 14 p., 2203053.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Culture density influences the functional phenotype of human macrophages

Ruder, A. V., Temmerman, L., van Dommelen, J. M. A., Nagenborg, J., Lu, C., Sluimer, J. C., Goossens, P. & Biessen, E. A. L., 10 Mar 2023, In: Frontiers in Immunology. 14, 1, 9 p., 1078591.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Endothelial ADAM10 controls cellular response to oxLDL and its deficiency exacerbates atherosclerosis with intraplaque hemorrhage and neovascularization in mice

van der Vorst, E. P. C., Maas, S. L., Theodorou, K., Peters, L. J. F., Jin, H., Rademakers, T., Gijbels, M. J., Rousch, M., Jansen, Y., Weber, C., Lehrke, M., Lebherz, C., Yildiz, D., Ludwig, A., Bentzon, J. F., Biessen, E. A. L. & Donners, M. M. P. C., 27 Jan 2023, In: Frontiers in Cardiovascular Medicine. 10, 1, 13 p., 974918.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

GM-CSF-activated STAT5A regulates macrophage functions and inflammation in atherosclerosis

Nagenborg, J., Jin, H., Ruder, A. V., Temmerman, L., Mees, B., Schalkwijk, C., Müller-Klieser, D., Berg, T., Goossens, P., Donners, M. M. P. C. & Biessen, E. A. L., 18 Oct 2023, In: Frontiers in Immunology. 14, 14 p., 1165306.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Human and murine fibroblast single-cell transcriptomics reveals fibroblast clusters are differentially affected by ageing and serum cholesterol

van Kuijk, K., McCracken, I. R., Tillie, R. J. H. A., Asselberghs, S. E. J., Kheder, D. A., Muitjens, S., Jin, H., Taylor, R. S., Schreur, R. W., Kuppe, C., Dobie, R., Ramachandran, P., Gijbels, M. J., Temmerman, L., Kirkwoord, P. M., Luyten, J., Li, Y. M., Noels, H., Goossens, P. & Wilson-Kanamori, J. R. & 8 others, Schurgers, L. J., Shen, Y. H., Mees, B. M. E., Biessen, E. A. L., Henderson, N. C., Kramann, R., Baker, A. H. & Sluimer, J. C., 4 Jul 2023, In: Cardiovascular Research. 119, 7, p. 1509-1523 15 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Identification Of A Prdm1-Regulated T-Cell Network Which Controls T-Cell Driven Plaque Inflammation In Human And Mouse Atherosclerosis

Maas, S., Jin, H., Lu, C., Nagenborg, J., Manca, M., Karel, J., Cavill, R., Sikkink, C., Yu, B., Nadeau, S., Dos Santos, J., Gijbels, M., Mees, B., Smirnov, E., Sluimer, J., Martins, G., Van der Vorst, E. & Biessen, E., 1 Aug 2023, In: Atherosclerosis. 379, S1, p. S11-S11 1 p.

Research output: Contribution to journal › Conference Abstract/Poster in journal › Academic

Mast cells participate in smooth muscle cell reprogramming and atherosclerotic plaque calcification

Skenteris, N. T., Hemme, E., Delfos, L., Karadimou, G., Karlof, E., Lengquist, M., Kronqvist, M., Zhang, X., Maegdefessel, L., Schurgers, L. J., Arnardottir, H., Biessen, E. A. L., Bot, I. & Matic, L., 1 Jun 2023, In: Vascular Pharmacology. 150, 1, 13 p., 107167.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Monocyte heterogeneity in cardiovascular disease

Ruder, A., Wetzels, S. M. W., Temmerman, L., Biessen, E. A. L. & Goossens, P., 5 Sept 2023, In: Cardiovascular Research. 119, 11, p. 2033-2045 13 p.

Research output: Contribution to journal › (Systematic) Review article › peer-review

Open Access

Protocol for multispectral imaging on cryosections to map myeloid cell heterogeneity in its spatial context

Wieland, E. B., Kempen, L. J. A. P., Lu, C., Donners, M. M. P. C., Biessen, E. A. L. & Goossens, P., 15 Dec 2023, In: STAR protocols. 4, 4, 17 p., 102601.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Sex-specific differences in cytokine signaling pathways in circulating monocytes of cardiovascular disease patients

Lu, C., Donners, M. M. P. C., Karel, J., de Boer, H., van Zonneveld, A. J., den Ruijter, H., Jukema, J. W., Kraaijeveld, A., Kuiper, J., Pasterkamp, G., Cavill, R., Perales-Patón, J., Ferrannini, E., Goossens, P. & Biessen, E. A. L., Nov 2023, In: Atherosclerosis. 384, 10 p., 117123.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

2022

Deficiency of myeloid PHD proteins aggravates atherogenesis via macrophage apoptosis and paracrine fibrotic signalling

van Kuijk, K., Demandt, J. A. F., Perales-Patón, J., Theelen, T. L., Kuppe, C., Marsch, E., de Bruijn, J., Jin, H., Gijbels, M. J., Matic, L., Mees, B. M. E., Reutelingsperger, C. P. M., Hedin, U., Biessen, E. A. L., Carmeliet, P., Baker, A. H., Kramann, R. K., Schurgers, L. J., Saez-Rodriguez, J. & Sluimer, J. C., 25 Mar 2022, In: Cardiovascular Research. 118, 5, p. 1232-1246 15 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Editorial: DNA repair and immune response

Basso, P. J., Rocha, C. R. R., Biessen, E. A. L., der Pluijm, I. V., Menck, C. F. M. & Câmara, N. O. S., 30 Sept 2022, In: Frontiers in Immunology. 13, p. 1034689 1034689.

Research output: Contribution to journal › Editorial › Academic › peer-review

Open Access

Identification of a PRDM1-regulated T cell network to regulate T cell driving plaque inflammation in human and mouse atherosclerosis

Maas, S. L., Jin, H., Lu, C., Nagenborg, J., Karel, J. M. H., Cavill, R., Sikkink, C. J. J. M., Nadeau, S., Gijbels, M., Mees, B. M. E., Smirnov, E., Sluimer, J. C., Martins, G. A., Van der Vorst, E. P. C. & Biessen, E. A. L., 1 Oct 2022, In: European Heart Journal. 43, p. 3049-3049 1 p.

Research output: Contribution to journal › Conference Abstract/Poster in journal › Academic

Open Access

Identification of CD8+T cell PRDM1 in high-risk human plaques and its regulatory role in murine lesion development

Maas, S. L., Jin, H., Lu, C., Nagenborg, J., Manca, M., Karel, J. M. H., Cavill, R., Waring, O., Sikkink, C. J. J. M., Mees, B. M. E., Daemen, M. J. A. P., Smirnov, E., Sluimer, J., van der Vorst, E. P. C. & Biessen, E. A. L., 10 Jun 2022, In: Cardiovascular Research. 118, SUPPL 1, 1 p.

Research output: Contribution to journal › Conference Abstract/Poster in journal › Academic

Open Access

Identification Of Cd8+T Cell Prdm1 In High-Risk Human Plaques And Its Regulatory Role In Murine Lesion Development

Jin, H., Maas, S. L., Lu, C., Nagenborg, J., Manca, M., Karel, J. M. H., Cavill, R., Waring, O., Sikkink, C. J. J. M., Mees, B. M. E., Daemen, M. J. A. P., Smirnov, E., Sluimer, J., Van der Vorst, E. & Biessen, E. A. L., 1 Aug 2022, In: Atherosclerosis. 355, p. E9-E9 1 p.

Research output: Contribution to journal › Conference Abstract/Poster in journal › Academic

Integrating multiplex immunofluorescent and mass spectrometry imaging to map myeloid heterogeneity in its metabolic and cellular context

Goossens, P., Lu, C., Cao, J., Gijbels, M. J., Karel, J. M. H., Wijnands, E., Claes, B. S. R., Fazzi, G. E., Hendriks, T. F. E., Wouters, K., Smirnov, E., van Zandvoort, M. J. M., Balluff, B., Cuypers, E., Donners, M. M. P. C., Heeren, R. M. A. & Biessen, E. A. L., 2 Aug 2022, In: Cell Metabolism. 34, 8, p. 1214-1225.e6 19 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Low Density Lipoprotein Exposure of Plasmacytoid Dendritic Cells Blunts Toll-like Receptor 7/9 Signaling via NUR77

Christ, A., Goossens, P. G., Wijnands, E., Jin, H., Legein, B., Oth, T., Isaacs, A., Stoll, M., Vanderlocht, J., Lutgens, E., Daemen, M. J. A. P., Zenke, M. & Biessen, E. A. L., 17 May 2022, In: Biomedicines. 10, 5, 17 p., 1152.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Magnetic resonance imaging contrast-enhancement with superparamagnetic iron oxide nanoparticles amplifies macrophage foam cell apoptosis in human and murine atherosclerosis

Segers, F. M. E., Ruder, A. V., Westra, M. M., Lammers, T., Dadfar, S. M., Roemhild, K., Lam, T. S., Eline Kooi, M., Cleutjens, K. B. J. M., Verheyen, F. K., Schurink, G. W. H., Haenen, G. R., van Berkel, T. J. C., Bot, I., Halvorsen, B., Sluimer, J. C. & Biessen, E. A. L., 2022, In: Cardiovascular Research. 118, p. 3346-3359 14 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

MicroRNA-26b Attenuates Platelet Adhesion and Aggregation in Mice

Peters, L. J. F., Baaten, C. C. F. M. J., Maas, S. L., Lu, C., Nagy, M., Jooss, N. J., Bidzhekov, K., Santovito, D., Moreno-Andrés, D., Jankowski, J., Biessen, E. A. L., Döring, Y., Heemskerk, J. W. M., Weber, C., Kuijpers, M. J. E. & van der Vorst, E. P. C., May 2022, In: Biomedicines. 10, 5, 14 p., 983.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Pro-oxidative priming but maintained cardiac function in a broad spectrum of murine models of chronic kidney disease

Wollenhaupt, J., Frisch, J., Harlacher, E., Wong, D. W. L., Jin, H., Schulte, C., Vondenhoff, S., Moellmann, J., Klinkhammer, B. M., Zhang, L., Baleanu-Curaj, A., Liehn, E. A., Speer, T., Kazakov, A., Werner, C., van der Vorst, E. P. C., Selejan, S.-R., Hohl, M., Böhm, M. & Kramann, R. & 8 others, Biessen, E. A. L., Lehrke, M., Marx, N., Jankowski, J., Maack, C., Boor, P., Prates Roma, L. & Noels, H., Oct 2022, In: Redox Biology. 56, 14 p., 102459.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Protective role of chaperone-mediated autophagy against atherosclerosis

Madrigal-Matute, J., de Bruijn, J., van Kuijk, K., Riascos-Bernal, D. F., Diaz, A., Tasset, I., Martín-Segura, A., Gijbels, M. J. J., Sander, B., Kaushik, S., Biessen, E. A. L., Tiano, S., Bourdenx, M., Krause, G. J., McCracken, I., Baker, A. H., Jin, H., Sibinga, N. E. S., Bravo-Cordero, J. J. & Macian, F. & 6 others, Singh, R., Rensen, P. C. N., Berbée, J. F. P., Pasterkamp, G., Sluimer, J. C. & Cuervo, A. M., 5 Apr 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 14, 12 p., e2121133119.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Temporal Transcript Profiling Identifies a Role for Unfolded Protein Stress in Human Gut Ischemia-Reperfusion Injury

Kip, A. M., Grootjans, J., Manca, M., Hadfoune, M., Boonen, B., Derikx, J. P. M., Biessen, E. A. L., Olde Damink, S. W. M., Dejong, C. H. C., Buurman, W. A. & Lenaerts, K., 2022, In: Cellular and molecular gastroenterology and hepatology. 13, 3, p. 681-694 14 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Triglyceride breakdown from lipid droplets regulates the inflammatory response in macrophages

van Dierendonck, X. A. M. H., Vrieling, F., Smeehuijzen, L., Deng, L., Boogaard, J. P., Croes, C. A., Temmerman, L., Wetzels, S., Biessen, E., Kersten, S. & Stienstra, R., 22 Mar 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 12, 12 p., e2114739119.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Two-faced Janus: The dual role of macrophages in atherosclerotic calcification

Waring, O. J., Skenteris, N. T., Biessen, E. A. L. & Donners, M. M. P. C., 1 Sept 2022, In: Cardiovascular Research. 118, 13, p. 2768–2777 10 p.

Research output: Contribution to journal › (Systematic) Review article › peer-review

Open Access

Unwrapped and uNCORked: PPAR-γ repression in atherosclerosis

Van der Vorst, E. P. C. & Biessen, E. A. L., 12 Feb 2022, In: European Heart Journal. 43, 7, p. E32-E34 3 p., ehz770.

Research output: Contribution to journal › Editorial › Academic › peer-review

2021

Adipocyte calcium sensing receptor is not involved in visceral adipose tissue inflammation or atherosclerosis development in hyperlipidemic Apoe(-/-) mice

Sundararaman, S. S., Peters, L. J. F., Jansen, Y., Gencer, S., Yan, Y., Nazir, S., Marquez, A. B., Kahles, F., Lehrke, M., Biessen, E. A. L., Jankowski, J., Weber, C., Doering, Y. & van der Vorst, E. P. C., 17 May 2021, In: Scientific Reports. 11, 1, 9 p., 10409.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Arterial lymphangiogenesis ReSPONDINg 2 a new cue: the R-spondin2/LRG4 axis limits VEGFR3-mediated lymphangiogenesis and reverse cholesterol transport

Sluimer, J. C. & Biessen, E. A. L., 1 Jun 2021, In: Cardiovascular Research. 117, 6, p. 1417-1419 3 p.

Research output: Contribution to journal › Editorial › Academic › peer-review

Open Access

A Switch from Cell-Associated to Soluble PDGF-B Protects against Atherosclerosis, despite Driving Extramedullary Hematopoiesis

Tillie, R. J. H. A., Theelen, T. L., van Kuijk, K., Temmerman, L., de Bruijn, J., Gijbels, M., Betsholtz, C., Biessen, E. A. L. & Sluimer, J. C., 10 Jul 2021, In: Cells. 10, 7, 18 p., 1746.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

CCR6 Deficiency Increases Infarct Size after Murine Acute Myocardial Infarction

Schumacher, D., Liehn, E. A., Singh, A., Curaj, A., Wijnands, E., Lira, S. A., Tacke, F., Jankowski, J., Biessen, E. A. L. & van der Vorst, E. P. C., 1 Nov 2021, In: Biomedicines. 9, 11, 11 p., 1532.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Development of the BioHybrid Assay: Combining Primary Human Vascular Smooth Muscle Cells and Blood to Measure Vascular Calcification Propensity

Jaminon, A. M. G., Akbulut, A. C., Rapp, N., Kramann, R., Biessen, E. A. L., Temmerman, L., Mees, B., Brandenburg, V., Dzhanaev, R., Jahnen-Dechent, W., Floege, J., Uitto, J., Reutelingsperger, C. P. & Schurgers, L. J., 1 Aug 2021, In: Cells. 10, 8, 13 p., 2097.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

DNA glycosylase Neil3 regulates vascular smooth muscle cell biology during atherosclerosis development

Quiles-Jimenez, A., Gregersen, I., Segers, F. M., Skarpengland, T., Kroustallaki, P., Yang, K., Kong, X. Y., Lauritzen, K. H., Olsen, M. B., Karlsen, T. R., Nyman, T. A., Sagen, E. L., Bjerkeli, V., Suganthan, R., Nygard, S., Scheffler, K., Prins, J., Van der Veer, E., Ogaard, J. D. S. & Floisand, Y. & 10 others, Jorgensen, H. F., Holven, K. B., Biessen, E. A., Nilsen, H., Dahl, T. B., Holm, S., Bennett, M. R., Aukrust, P., Bjoras, M. & Halvorsen, B., May 2021, In: Atherosclerosis. 324, p. 123-132 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Efficacy and safety of spore-forming probiotics in the treatment of functional dyspepsia: a pilot randomised, double-blind, placebo-controlled trial

Wauters, L., Slaets, H., De Paepe, K., Ceulemans, M., Wetzels, S., Geboers, K., Toth, J., Thys, W., Dybajlo, R., Walgraeve, D., Biessen, E., Verbeke, K., Tack, J., Van de Wiele, T., Hellings, N. & Vanuytsel, T., 1 Oct 2021, In: The Lancet Gastroenterology and Hepatology. 6, 10, p. 784-792 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

Integrative multiomics analysis of human atherosclerosis reveals a serum response factor-driven network associated with intraplaque hemorrhage

Jin, H., Goossens, P., Juhasz, P., Eijgelaar, W.-J., Manca, M., Karel, J., Smirnov, E., Sikkink, C. J. J. M., Mees, B., Waring, O., van Kuijk, K., Fazzi, G., Gijbels, M., Kutmon, M., Evelo, C., Hedin, U., Daemen, M. J., Sluimer, J., Matic, L. P. & Biessen, E., 27 Jun 2021, In: Clinical and Translational Medicine. 11, 6, 21 p., e458.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

N-Acetyl Galactosamine Targeting: Paving the Way for Clinical Application of Nucleotide Medicines in Cardiovascular Diseases

Biessen, E. A. L. & Van Berkel, T. J. C., 1 Dec 2021, In: Arteriosclerosis Thrombosis and Vascular Biology. 41, 12, p. 2855-2865 11 p.

Research output: Contribution to journal › (Systematic) Review article › peer-review

Open Access

Non-canonical glutamine transamination sustains efferocytosis by coupling redox buffering to oxidative phosphorylation

Merlin, J., Ivanov, S., Dumont, A., Sergushichev, A., Gall, J., Stunault, M., Ayrault, M., Vaillant, N., Castiglione, A., Swain, A., Orange, F., Gallerand, A., Berton, T., Martin, J.-C., Carobbio, S., Masson, J., Gaisler-Salomon, I., Maechler, P., Rayport, S. & Sluimer, J. C. & 6 others, Biessen, E. A. L., Guinamard, R. R., Gautier, E. L., Thorp, E. B., Artyomov, M. N. & Yvan-Charvet, L., Oct 2021, In: Nature Metabolism. 3, 10, p. 1313-1326 29 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

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Proteoglycan 4 Modulates Osteogenic Smooth Muscle Cell Differentiation during Vascular Remodeling and Intimal Calcification

Seime, T., Akbulut, A. C., Liljeqvist, M. L., Siika, A., Jin, H., Winski, G., van Gorp, R. H., Karlöf, E., Lengquist, M., Buckler, A. J., Kronqvist, M., Waring, O. J., Lindeman, J. H. N., Biessen, E. A. L., Maegdefessel, L., Razuvaev, A., Schurgers, L. J., Hedin, U. & Matic, L., 21 May 2021, In: Cells. 10, 6, 26 p., 1276.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Erik Biessen

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