Temporal Transcript Profiling Identifies a Role for Unfolded Protein Stress in Human Gut Ischemia-Reperfusion Injury

Anna M Kip, Joep Grootjans, Marco Manca, M'hamed Hadfoune, Bas Boonen, Joep P M Derikx, Erik A L Biessen, Steven W M Olde Damink, Cornelis H C Dejong, Wim A Buurman, Kaatje Lenaerts*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Web of Science)
Original languageEnglish
Pages (from-to)681-694
Number of pages14
JournalCellular and molecular gastroenterology and hepatology
Volume13
Issue number3
Early online date11 Nov 2021
DOIs
Publication statusPublished - 2022

Keywords

  • Transcriptomics
  • Intestinal Ischemia-Reperfusion
  • Unfolded Protein Response
  • Human Intestinal Organoids
  • ENDOPLASMIC-RETICULUM STRESS
  • HYPOXIA-INDUCIBLE FACTOR
  • INDUCED INFLAMMATION
  • CELL-SURVIVAL
  • FACTOR-I
  • KAPPA-B
  • ER
  • ACTIVATION
  • KINASE
  • DEATH

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