20042020

Research output per year

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Research Output

2020

Biperiden Selectively Impairs Verbal Episodic Memory in a Dose- and Time-Dependent Manner in Healthy Subjects

Borghans, L., Sambeth, A. & Blokland, A., 2020, In : Journal of Clinical Psychopharmacology. 40, 1, p. 30-37 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2019

Acute treatment with the PDE4 inhibitor roflumilast improves verbal word memory in healthy old individuals: a double-blind placebo-controlled study

Blokland, A., Van Duinen, M. A., Sambeth, A., Heckman, P. R. A., Tsai, M., Lahu, G., Uz, T. & Prickaerts, J., May 2019, In : Neurobiology of Aging. 77, p. 37-43 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

No interaction between rivastigmine and citalopram on memory and novelty processing in healthy human volunteers

Heckman, P. R. A., Blokland, A. & Sambeth, A., Feb 2019, In : Journal of Psychopharmacology. 33, 2, p. 210-218 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2018

Acute administration of roflumilast enhances immediate recall of verbal word memory in healthy young adults

Van Duinen, M. A., Sambeth, A., Heckman, P. R. A., Smit, S., Tsai, M., Lahu, G., Uz, T., Blokland, A. & Prickaerts, J., 15 Mar 2018, In : Neuropharmacology. 131, p. 31-38 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Acute administration of roflumilast enhances sensory gating in healthy young humans in a randomized trial

Heckman, P. R. A., Van Duinen, M. A., Blokland, A., Uz, T., Prickaerts, J. & Sambeth, A., Jan 2018, In : Psychopharmacology. 235, 1, p. 301–308 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The effects of the soluble guanylate cyclase stimulator riociguat on memory performance in healthy volunteers with a biperiden-induced memory impairment

Borghans, L. G. J. M., Sambeth, A., Prickaerts, J., Ramaekers, J. G. & Blokland, A., Aug 2018, In : Psychopharmacology. 235, 8, p. 2407-2416 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2017

A combination of nootropic ingredients (CAF+) is not better than caffeine in improving cognitive functions

Caldenhove, S., Sambeth, A., Sharma, S., G., W. & Blokland, A., 18 Dec 2017, In : Journal of Cognitive Enhancement. 2, 1, p. 106-113

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Effects of biperiden and acute tryptophan depletion and their combination on verbal memory and electroencephalography

Borghans, L., Blokland, A. & Sambeth, A., Mar 2017, In : European Neuropsychopharmacology. 27, p. S65-S66

Research output: Contribution to journalConference Abstract/Poster in journalAcademic

Effects of biperiden and acute tryptophan depletion and their combination on verbal word memory and EEG

Borghans, L. G. J. M., Blokland, A. & Sambeth, A., Apr 2017, In : Psychopharmacology. 234, 7, p. 1135-1143

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Effects of riociguat and biperiden on memory

Borghans, L. G. J. M., Sambeth, A., Prickaerts, J. H. H. J., Ramaekers, J. G. & Blokland, A., Oct 2017, p. S645-S645.

Research output: Contribution to conferencePosterAcademic

Role of acetylcholine and serotonin in novelty processing using an oddball paradigm

Caldenhove, S., Borghans, L., Blokland, A. & Sambeth, A., 28 Jul 2017, In : Behavioural Brain Research. 331, p. 199-204 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The PDE4-inhibitor roflumilast improves memory: findings from a translational perspective

Van Duinen, M. A., Sambeth, A., Heckman, P. R. A., Tsai, M., Lahu, G., Uz, T., Blokland, A. & Prickaerts, J., Oct 2017, In : European Neuropsychopharmacology. 27, Suppl 4, p. S1024-S1025

Research output: Contribution to journalConference Abstract/Poster in journalAcademic

2016

The PDE4 inhibitor roflumilast improves memory in rodents at non-emetic doses

Vanmierlo, T., Creemers, P., Akkerman, S., van Duinen, M., Sambeth, A., De Vry, J., Uz, T., Blokland, A. & Prickaerts, J., 15 Apr 2016, In : Behavioural Brain Research. 303, p. 26-33 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Verbal memory impairment in polydrug ecstasy users: A clinical perspective

Kuypers, K. P. C., Theunissen, E. L., van Wel, J. H. P., de Sousa, E. B., Perna, F., Linssen, A., Sambeth, A., Schultz, B. G. & Ramaekers, J. G., 23 Feb 2016, In : PLOS ONE. 11, 2, 0149438.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
1 Citation (Scopus)
152 Downloads (Pure)

Why an M1 Antagonist Could Be a More Selective Model for Memory Impairment than Scopolamine

Blokland, A., Sambeth, A., Prickaerts, J. & Riedel, W. J., 30 Sep 2016, In : Frontiers in Neurology. 7, 4 p., 167.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
140 Downloads (Pure)
2015

Biperiden selectively induces memory impairment in healthy volunteers : no interaction with citalopram

Sambeth, A., Riedel, W. J., Klinkenberg, I., Kähkönen, S. & Blokland, A., 1 Jan 2015, In : Psychopharmacology. 232, 11, p. 1887-1897

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)

Rivastigmine but not vardenafil reverses cannabis-induced impairment of verbal memory in healthy humans

Theunissen, E. L., Heckman, P., de Sousa Fernandes Perna, E. B., Kuypers, K. P. C., Sambeth, A., Blokland, A., Prickaerts, J., Toennes, S. W. & Ramaekers, J. G., 1 Jan 2015, In : Psychopharmacology. 232, 2, p. 343-353 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

The use of EEG parameters as predictors of drug effects on cognition

Blokland, A., Prickaerts, J., van Duinen, M. & Sambeth, A., 15 Jul 2015, In : European Journal of Pharmacology. 759, p. 163-168 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Treatment of cognitive impairment in schizophrenia: potential value of phosphodiesterase inhibitors in prefrontal dysfunction

van Duinen, M., Reneerkens, O. A. H., Lambrecht, L., Sambeth, A., Rutten, B. P. F., van Os, J., Blokland, A. & Prickaerts, J., 1 Jan 2015, In : Current Pharmaceutical Design. 21, 26, p. 3813-3828 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)
2014

Cognitive effects of methylphenidate and levodopa in healthy volunteers

Linssen, A. M. W., Sambeth, A., Vuurman, E. F. P. M. & Riedel, W. J., 1 Jan 2014, In : European Neuropsychopharmacology. 24, 2, p. 200-206

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)

Cognitive effects of methylphenidate in healthy volunteers: a review of single dose studies

Linssen, A. M. W., Sambeth, A., Vuurman, E. F. P. M. & Riedel, W. J., Jun 2014, In : International Journal of Neuropsychopharmacology. 17, 6, p. 961-977 17 p.

Research output: Contribution to journalArticleAcademicpeer-review

30 Citations (Scopus)

Effects of remifentanil on processing of auditory stimuli: A combined MEG/EEG study

Quaedflieg, C. W. E. M., Münte, S., Kalso, E. & Sambeth, A., 1 Jan 2014, In : Journal of Psychopharmacology. 28, 1, p. 39-48

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)
2013

Central nervous system-impairing effects of hydroxyzine as a function of histamine availability

Conen, S., Theunissen, E. L., Vermeeren, A., Sambeth, A. & Ramaekers, J. G., Apr 2013, In : Journal of Clinical Psychopharmacology. 33, 2, p. 276-279 4 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

Cholinergic gating of hippocampal auditory evoked potentials in freely moving rats

Klinkenberg, I., Sambeth, A. & Blokland, A., Aug 2013, In : European Neuropsychopharmacology. 23, 8, p. 988-997 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Cholinergic modulation of auditory processing, sensory gating and novelty detection in human participants

Klinkenberg, I., Blokland, A., Riedel, W. J. & Sambeth, A., Feb 2013, In : Psychopharmacology. 225, 4, p. 903-921 19 p.

Research output: Contribution to journalArticleAcademicpeer-review

13 Citations (Scopus)

Effects of remifentanil on cognitive and psychomotor functioning and mood

Münte, S., Quaedflieg, C. W. E. M., Sambeth, A., Wang, M. & Kalso, E., Sep 2013, In : British Journal of Anaesthesia. 111, 3, p. 517-518 2 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

3 Citations (Scopus)

Higher, faster, stronger: The effect of dynamic stimuli on response preparation and CNV amplitude

Linssen, A. M. W., Sambeth, A., Riedel, W. J. & Vuurman, E. F. P. M., 15 Jan 2013, In : Behavioural Brain Research. 237, p. 308-312 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

Learning-induced neural plasticity of speech processing before birth

Partanen, E., Kujala, T., Naatanen, R., Liitola, A., Sambeth, A. & Huotilainen, M., 10 Sep 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 37, p. 15145-15150 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

39 Citations (Scopus)

PDE2 and PDE10, but not PDE5, inhibition affect basic auditory information processing in rats

Reneerkens, O. A. H., Sambeth, A., Blokland, A. & Prickaerts, J., 1 Aug 2013, In : Behavioural Brain Research. 250, p. 251-256 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

The PDE5 inhibitor vardenafil does not affect auditory sensory gating in rats and humans

Reneerkens, O. A. H., Sambeth, A., van Duinen, M. A., Blokland, A., Steinbusch, H. W. M. & Prickaerts, J., 1 Jan 2013, In : Psychopharmacology. 225, 2, p. 303-312 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)
2012

Evoked magnetic fields from primary and secondary somatosensory cortices: A reliable tool for assessment of cortical processing in the neonatal period

Nevalainen, P., Pihko, E., Metsaranta, M., Sambeth, A., Wikstrom, H., Okada, Y., Autti, T. & Lauronen, L., Dec 2012, In : Clinical Neurophysiology. 123, 12, p. 2377-2383 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

10 Citations (Scopus)

Human electrophysiological correlates of learned irrelevance: effects of the muscarinic M1 antagonist biperiden

Klinkenberg, I., Blokland, A., Riedel, W. & Sambeth, A., Nov 2012, In : International Journal of Neuropsychopharmacology. 15, 10, p. 1375-1385 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Methylphenidate produces selective enhancement of declarative memory consolidation in healthy volunteers

Linssen, A. M. W., Vuurman, E. F. P. M., Sambeth, A. & Riedel, W. J., Jun 2012, In : Psychopharmacology. 221, 4, p. 611-619 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

31 Citations (Scopus)

Neurophysiological functioning of occasional and heavy cannabis users during THC intoxication

Theunissen, E., Kauert, G. F., Toennes, S. W., Moeller, M. R., Sambeth, A., Blanchard, M. M. & Ramaekers, J., 1 Jan 2012, In : Psychopharmacology. 220, 2, p. 341-350

Research output: Contribution to journalArticleAcademicpeer-review

29 Citations (Scopus)
2011

Acetylcholine and attention

Klinkenberg, I., Sambeth, A. & Blokland, A., 1 Jan 2011, In : Behavioural Brain Research. 221, 2, p. 430-442

Research output: Contribution to journalArticleAcademicpeer-review

97 Citations (Scopus)

Auditory P300 and N100 components as intermediate phenotypes for psychotic disorder: Familial liability and reliability

Simons, C. J. P., Sambeth, A., Krabbendam, A. C., Pfeifer, S., van Os, J. J. & Riedel, W. J., 1 Jan 2011, In : Clinical Neurophysiology. 122, 10, p. 1984-1990

Research output: Contribution to journalArticleAcademicpeer-review

Contingent negative variation as a dopaminergic biomarker: evidence from dose-related effects of methylphenidate

Linssen, A. M. W., Vuurman, E. F. P. M., Sambeth, A., Nave, S., Spooren, W., Vargas, G., Santarelli, L. & Riedel, W. J., Dec 2011, In : Psychopharmacology. 218, 3, p. 533-542 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

30 Citations (Scopus)

Dopaminergic modulation of cognitive function. the influence of methylphenidate on cognitive performance in healthy volunteers

Linssen, A. M. W., Vuurman, E., Sambeth, A., Nave, S. & Riedel, W., 1 Jan 2011, p. A30-A30.

Research output: Contribution to conferenceAbstractAcademic

Effects of tyrosine/phenylalanine depletion on electrophysiological correlates of memory in healthy volunteers

Linssen, A. M. W., Riedel, W. J. & Sambeth, A., Feb 2011, In : Journal of Psychopharmacology. 25, 2, p. 230-238 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

Enhanced dopamine availability and response readiness. The influence of 3 doses of methylphenidate on contingent negative variation in the EEG of healthy volunteers

Linssen, A. M. W., Vuurman, E. F. P. M., Sambeth, A., Navé, S. & Riedel, W. J., 1 Jan 2011, In : Neuroscience Letters. 500, suppl., e25.

Research output: Contribution to journalArticleAcademicpeer-review

Human eeg correlates of learned irrelevance: effects of the muscarinic m1 antagonist biperiden

Klinkenberg, I. P. M., Blokland, A. & Sambeth, A., 1 Jan 2011, p. A30-A30.

Research output: Contribution to conferenceAbstractAcademic

2010

Enhanced dopamine availability and response readiness. The influence of 3 doses of methylphenidate on contingent negative variation in the eeg of healthy volunteers

Linssen, A. M. W., Vuurman, E., Sambeth, A., Nave, S. & Riedel, W., 1 Jan 2010, p. A56-A56.

Research output: Contribution to conferenceAbstractAcademic

The effects of acute tryptophan depletion on brain activation during cognition and emotional processing in healthy volunteers.

Evers, E. A. T., Sambeth, A., Ramaekers, J. G., Riedel, W. J. & van der Veen, F. M., 1 Jan 2010, In : Current Pharmaceutical Design. 16, 18, p. 1998-2011

Research output: Contribution to journalArticleAcademicpeer-review

15 Citations (Scopus)
2009

Change detection in newborns using a multiple deviant paradigm: a study using magnetoencephalography

Sambeth, A., Pakarinen, S., Ruohio, K., Fellman, V., van Zuijen, T. L. & Huotilainen, M., 1 Jan 2009, In : Clinical Neurophysiology. 120, 3, p. 530-538

Research output: Contribution to journalArticleAcademicpeer-review

20 Citations (Scopus)

Effects of acute tryptophan depletion on memory, attention and executive functions: a systematic review

Mendelsohn, D., Riedel, W. J. & Sambeth, A., 1 Jan 2009, In : Neuroscience and Biobehavioral Reviews. 33, 6, p. 926-952

Research output: Contribution to journalArticleAcademicpeer-review

83 Citations (Scopus)
10 Citations (Scopus)

Hippocampal theta frequency and novelty

Sambeth, A., Meeter, M. & Blokland, A., 1 Jan 2009, In : Hippocampus. 19, p. 407-408;

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)
10 Citations (Scopus)

Memory impairments in humans after acute tryptophan depletion using a novel gelatin-based protein drink

Sambeth, A., Riedel, W. J., Tillie, D. E., Blokland, A., Postma, A. & Schmitt, J. A. J., 1 Jan 2009, In : Journal of Psychopharmacology. 23, 1, p. 56-64

Research output: Contribution to journalArticleAcademicpeer-review

24 Citations (Scopus)