The PDE4 inhibitor roflumilast improves memory in rodents at non-emetic doses

Tim Vanmierlo, Pim Creemers, Sven Akkerman, Marlies van Duinen, Anke Sambeth, Jochen De Vry, Tolga Uz, Arjan Blokland, Jos Prickaerts*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

57 Citations (Web of Science)
1 Downloads (Pure)
Original languageEnglish
Pages (from-to)26-33
Number of pages8
JournalBehavioural Brain Research
Publication statusPublished - 15 Apr 2016


  • PDE4
  • PDE4 inhibition
  • Roflumilast
  • Rolipram
  • Cognition
  • Memory
  • Emesis
  • cAMP

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