The PDE4 inhibitor roflumilast improves memory in rodents at non-emetic doses

Tim Vanmierlo; Pim Creemers; Sven Akkerman; Marlies van Duinen; Anke Sambeth; Jochen De Vry; Tolga Uz; Arjan Blokland; Jos Prickaerts

doi:10.1016/j.bbr.2016.01.031

The PDE4 inhibitor roflumilast improves memory in rodents at non-emetic doses

Tim Vanmierlo, Pim Creemers, Sven Akkerman, Marlies van Duinen, Anke Sambeth, Jochen De Vry, Tolga Uz, Arjan Blokland, Jos Prickaerts^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

57 Citations (Web of Science)

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Original language	English
Pages (from-to)	26-33
Number of pages	8
Journal	Behavioural Brain Research
Volume	303
DOIs	https://doi.org/10.1016/j.bbr.2016.01.031
Publication status	Published - 15 Apr 2016

Keywords

PDE4
PDE4 inhibition
Roflumilast
Rolipram
Cognition
Memory
Emesis
cAMP

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10.1016/j.bbr.2016.01.031

Full textFinal published version, 1.06 MBLicence: Taverne

Cite this

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title = "The PDE4 inhibitor roflumilast improves memory in rodents at non-emetic doses",

keywords = "PDE4, PDE4 inhibition, Roflumilast, Rolipram, Cognition, Memory, Emesis, cAMP",

author = "Tim Vanmierlo and Pim Creemers and Sven Akkerman and {van Duinen}, Marlies and Anke Sambeth and {De Vry}, Jochen and Tolga Uz and Arjan Blokland and Jos Prickaerts",

year = "2016",

month = apr,

day = "15",

doi = "10.1016/j.bbr.2016.01.031",

language = "English",

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journal = "Behavioural Brain Research",

issn = "0166-4328",

publisher = "Elsevier Science",

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T1 - The PDE4 inhibitor roflumilast improves memory in rodents at non-emetic doses

AU - Vanmierlo, Tim

AU - Creemers, Pim

AU - Akkerman, Sven

AU - van Duinen, Marlies

AU - Sambeth, Anke

AU - De Vry, Jochen

AU - Uz, Tolga

AU - Blokland, Arjan

AU - Prickaerts, Jos

PY - 2016/4/15

Y1 - 2016/4/15

KW - PDE4

KW - PDE4 inhibition

KW - Roflumilast

KW - Rolipram

KW - Cognition

KW - Memory

KW - Emesis

KW - cAMP

U2 - 10.1016/j.bbr.2016.01.031

DO - 10.1016/j.bbr.2016.01.031

M3 - Article

C2 - 26794595

VL - 303

SP - 26

EP - 33

JO - Behavioural Brain Research

JF - Behavioural Brain Research

SN - 0166-4328

ER -