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Research Output

2018

Cross-Species Molecular Imaging of Bile Salts and Lipids in Liver: Identification of Molecular Structural Markers in Health and Disease

Flinders, B., Huizing, L. R. S., van Heerden, M., Cuyckens, F., Neumann, U. P., van der Laan, L. J. W., Damink, S. W. M. O., Heeren, R. M. A., Schaap, F. G. & Vreeken, R. J., 16 Oct 2018, In : Analytical Chemistry. 90, 20, p. 11835-11846 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Farnesoid X Receptor (FXR) Agonist Obeticholic Acid (OCA) Restores Liver Regeneration after Partial Hepatectomy in Bile Acid Deprived Rats but Does Not Overdrive Natural FXR Activation in the Physiologic Process of Liver Regeneration

Dahrenmoller, C., Schaap, F. G., Damink, S. O., Van Mierlo, K., Jansen, P. L. M., Horsmans, Y. & Leclercq, I. A., 1 Oct 2018, In : Hepatology. 68, p. 827A-828A 2 p.

Research output: Contribution to journalConference Abstract/Poster in journalAcademic

FXR agonist obeticholic acid induces liver growth but exacerbates biliary injury in rats with obstructive cholestasis

van Golen, R. F., Olthof, P. B., Lionarons, D. A., Reiniers, M. J., Alles, L. K., Uz, Z., de Haan, L., Ergin, B., de Waart, D. R., Maas, A., Verheij, J., Jansen, P. L., Darnink, S. W. O., Schaap, F. G., van Gulik, T. M. & Heger, M., 8 Nov 2018, In : Scientific Reports. 8, 10 p., 16529.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Ophthalmic acid as a read-out for hepatic glutathione metabolism in humans

Kim Mc van, M., Dello, S. A., de Jong, M. C., van Eijk, H. M., de Kok, T. M., Briedé, J. J., Schaap, F. G., Damink, S. W. O. & Dejong, C. H., 30 Jul 2018, In : Journal of clinical and translational research. 3, Suppl 2, p. 366-374 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

The role of macrophages in the development of biliary injury in a lipopolysaccharide-aggravated hepatic ischaemia-reperfusion model

Reiling, J., Bridle, K. R., Schaap, F. G., Jaskowski, L., Santrampurwala, N., Britton, L. J., Campbell, C. M., Jansen, P. L. M., Damink, S. W. M. O., Crawford, D. H. G., Dejong, C. H. C. & Fawcett, J., Apr 2018, In : Biochimica et Biophysica Acta-Molecular Basis of Disease. 1864, 4, p. 1284-1292 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

2019

Differential effects of a 40-hour fast and bile acid supplementation on human GLP-1 and FGF19 responses

van Nierop, F. S., Meessen, E. C. E., Nelissen, K. G. M., Achterbergh, R., Lammers, L. A., Vaz, F. M., Mathot, R. A. A., Klumpen, H-J., Damink, S. W. O., Schaap, F. G., Romijn, J. A., Kemper, E. M. & Soeters, M. R., Sep 2019, In : American Journal of Physiology : Endocrinology and Metabolism. 317, 3, p. E494-E502 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Duodenal-jejunal lining increases postprandial unconjugated bile acid responses and disrupts the bile acid-FXR-FGF19 axis in humans

van Nierop, F. S., de Jonge, C., Kulik, W., Bouvy, N., Schaap, F. G., Damink, S. W. O., Rensen, S., Romijn, J. A., Greve, J. W. M. & Soeters, M. R., Apr 2019, In : Metabolism-Clinical and Experimental. 93, p. 25-32 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Effect of Plasmapheresis on Cholestatic Pruritus and Autotaxin Activity During Pregnancy

Heerkens, M., Dedden, S., Scheepers, H., Van Paassen, P., Masclee, A., de Die-Smulders, C., Olde Damink, S. W. M., Schaap, F. G., Jansen, P., Koek, G., Beuers, U. & Verbeek, J., Jun 2019, In : Hepatology. 69, 6, p. 2707-2710 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Gallbladder Dyskinesia Is Associated With an Impaired Postprandial Fibroblast Growth Factor 19 Response in Critically Ill Patients

Koelfat, K. V. K., Plummer, M. P., Schaap, F. G., Lenicek, M., Jansen, P. L. M., Deane, A. M. & Damink, S. W. M. O., Jul 2019, In : Hepatology. 70, 1, p. 308-318 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

The cholic acid extension study in Zellweger spectrum disorders: Results and implications for therapy

Klouwer, F. C. C., Koot, B. G. P., Berendse, K., Kemper, E. M., Ferdinandusse, S., Koelfat, K. V. K., Lenicek, M., Vaz, F. M., Engelen, M., Jansen, P. L. M., Wanders, R. J. A., Waterham, H. R., Schaap, F. G. & Poll-The, B. T., Mar 2019, In : Journal of Inherited Metabolic Disease. 42, 2, p. 303-312 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2020

Bile acids drive the newborn's gut microbiota maturation

van Best, N., Rolle-Kampczyk, U., Schaap, F. G., Basic, M., Damink, S. W. M. O., Bleich, A., Savelkoul, P. H. M., von Bergen, M., Penders, J. & Hornef, M. W., 23 Jul 2020, In : Nature Communications. 11, 1, 13 p., 3692.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access