Validation of gene expression profiles from cholestatic hepatotoxicants in vitro against human in vivo cholestasis

Wim F. P. M. Van den Hof*, Maarten L. J. Coonen, Marcel van Herwijnen, Karen Brauers, Danyel Jennen, Steven W. M. Olde Damink, Frank G. Schaap, Jos C. S. Kleinjans

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)322-329
Number of pages8
JournalToxicology in Vitro
Volume44
DOIs
Publication statusPublished - Oct 2017

Keywords

  • Cholestasis
  • Hepatotoxicity
  • Liver
  • HepG2
  • Primary human hepatocytes
  • Primary mouse hepatocytes
  • SALT EXPORT PUMP
  • PATHWAY
  • HEPATOCYTES
  • LIVER
  • CHLORPROMAZINE
  • INHIBITION
  • METABOLISM
  • SULFATION
  • GROWTH
  • CELLS

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