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Research Output 2010 2019

2019

Extracellular Vesicles as Transmitters of Hypoxia Tolerance in Solid Cancers

Zonneveld, M. I., Keulers, T. G. H. & Rouschop, K. M. A., Feb 2019, In : Cancers. 11, 2, 17 p., 154.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Tumour hypoxia: Effects on autophagy and intercellular communication

Keulers, T., 2019

Research output: ThesisDoctoral ThesisInternal

2018

EGFRvIII expression triggers a metabolic dependency and therapeutic vulnerability sensitive to autophagy inhibition

Jutten, B., Keulers, T. G., Peeters, H. J. M., Schaaf, M. B. E., Savelkouls, K. G. M., Compter, I., Clarijs, R., Schijns, O. E. M. G., Ackermans, L., Teernstra, O. P. M., Zonneveld, M. I., Colaris, R. M. E., Dubois, L., Vooijs, M. A., Bussink, J., Sotelo, J., Theys, J., Lammering, G. & Rouschop, K. M. A., 1 Jan 2018, In : Autophagy. 14, 2, p. 283-295 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2017

Leukocyte Bim deficiency does not impact atherogenesis in ldlr(-/-) mice, despite a pronounced induction of autoimmune inflammation

Temmerman, L., Westra, M. M., Bot, I., van Vlijmen, B. J. M., Van Bree, N., Bot, M., Habets, K. L. L., Keulers, T. G. H., van der Vlag, J., Cotter, T. G., van Berkel, T. J. C. & Biessen, E. A. L., 8 Jun 2017, In : Scientific Reports. 7, 11 p., 3086.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2016

Autophagy-Dependent Secretion: Contribution to Tumor Progression

Keulers, T. G., Schaaf, M. B. E. & Rouschop, K. M. A., 25 Nov 2016, In : Frontiers in Oncology. 6, 251.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
5 Citations (Scopus)

LC3/GABARAP family proteins: autophagy-(un) related functions

Schaaf, M. B. E., Keulers, T. G., Vooijs, M. A. & Rouschop, K. M. A., Dec 2016, In : Faseb Journal. 30, 12, p. 3961-3978

Research output: Contribution to journalArticleAcademicpeer-review

2015
4 Citations (Scopus)

GABARAPL1 is required for increased EGFR membrane expression during hypoxia

Keulers, T. G., Schaaf, M. B. E., Peeters, H. J. M., Savelkouls, K. G. M., Vooijs, M. A., Bussink, J., Jutten, B. & Rouschop, K. M. A., Sep 2015, In : Radiotherapy and Oncology. 116, 3, p. 417-422

Research output: Contribution to journalArticleAcademicpeer-review

2013
8 Citations (Scopus)

EGFR overexpressing cells and tumors are dependent on autophagy for growth and survival

Jutten, B., Keulers, T. G., Schaaf, M. B. E., Savelkouls, K., Theys, J., Span, P. N., Vooijs, M. A., Bussink, J. & Rouschop, K. M. A., Sep 2013, In : Radiotherapy and Oncology. 108, 3, p. 479-483

Research output: Contribution to journalArticleAcademicpeer-review

51 Citations (Scopus)
18 Citations (Scopus)

The autophagy associated gene, ULK1, promotes tolerance to chronic and acute hypoxia

Schaaf, M. B. E., Cojocari, D., Keulers, T. G., Jutten, B., Starmans, M. H., de Jong, M. C., Begg, A. C., Savelkouls, K. G. M., Bussink, J., Vooijs, M., Wouters, B. G. & Rouschop, K. M. A., Sep 2013, In : Radiotherapy and Oncology. 108, 3, p. 529-534

Research output: Contribution to journalArticleAcademicpeer-review

2011

Deregulation of cap-dependent mRNA translation increases tumour radiosensitivity through reduction of the hypoxic fraction

Rouschop, K. M. A., Dubois, L., Schaaf, M. B. E., van den Beucken, T., Lieuwes, N., Keulers, T. G. H., Savelkouls, K. G. M., Bussink, J., van der Kogel, A. J., Koritzinsky, M. & Wouters, B. G., Jun 2011, In : Radiotherapy and Oncology. 99, 3, p. 385-391

Research output: Contribution to journalArticleAcademicpeer-review

2010

The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5

Rouschop, K. M. A., van den Beucken, T., Dubois, L., Niessen, H., Bussink, J., Savelkouls, K., Keulers, T., Mujcic, H., Landuyt, W., Voncken, J. W., Lambin, P., van der Kogel, A. J., Koritzinsky, M. & Wouters, B. G., Jan 2010, In : Journal of Clinical Investigation. 120, 1, p. 127-141

Research output: Contribution to journalArticleAcademicpeer-review