Deregulation of cap-dependent mRNA translation increases tumour radiosensitivity through reduction of the hypoxic fraction

Kasper M. A. Rouschop*, Ludwig Dubois, Marco B. E. Schaaf, Twan van den Beucken, Natasja Lieuwes, Tom G. H. Keulers, Kim G. M. Savelkouls, Johan Bussink, Albert J. van der Kogel, Marianne Koritzinsky, Bradly G. Wouters

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

20 Citations (Web of Science)
9 Downloads (Pure)
Original languageEnglish
Pages (from-to)385-391
JournalRadiotherapy and Oncology
Issue number3
Publication statusPublished - Jun 2011


  • eIF4E
  • mTOR
  • Hypoxia
  • Necrosis
  • Irradiation

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