Deregulation of cap-dependent mRNA translation increases tumour radiosensitivity through reduction of the hypoxic fraction

Kasper M. A. Rouschop, Ludwig Dubois, Marco B. E. Schaaf, Twan van den Beucken, Natasja Lieuwes, Tom G. H. Keulers, Kim G. M. Savelkouls, Johan Bussink, Albert J. van der Kogel, Marianne Koritzinsky, Bradly G. Wouters

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)385-391
JournalRadiotherapy and Oncology
Volume99
Issue number3
DOIs
Publication statusPublished - Jun 2011

Keywords

  • eIF4E
  • mTOR
  • Hypoxia
  • Necrosis
  • Irradiation

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