MERLN - Institute for Technology-Inspired Regenerative Medicine

Research output

Research output per year 2014 2016 2017 2020 2021 2022 2023 2024

• 554 Article
• 100 (Systematic) Review article
• 39 Doctoral Thesis
• 28 Chapter
• 44 More
  • 14 Editorial
  • 9 Erratum / corrigendum / retractions
  • 8 Conference article in proceeding
  • 7 Conference Abstract/Poster in journal
  • 3 Inaugural speech
  • 1 Book
  • 1 Report
  • 1 Web publication/site

Research output per year

Research output per year

Search results

• 2024

  3D Niche-Inspired Scaffolds as a Stem Cell Delivery System for the Regeneration of the Osteochondral Interface

  Camarero-Espinosa, S., Beeren, I., Liu, H., Gomes, D. B., Zonderland, J., Lourenço, A. F. H., van Beurden, D., Peters, M., Koper, D., Emans, P., Kessler, P., Rademakers, T., Baker, M. B., Bouvy, N. & Moroni, L., 16 Jan 2024, In: Advanced Materials. 15 p., 2310258.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• A Modular Microfluidic Organoid Platform Using LEGO® -like Bricks

  Carvalho, D. J., Kip, A. M., Tegel, A., Stich, M., Krause, C., Romitti, M., Branca, C., Verhoeven, B., Costagliola, S., Moroni, L. & Giselbrecht, S., 21 Jan 2024, (E-pub ahead of print) In: Advanced Healthcare Materials. 13 p., 2303444.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Amorphous magnesium phosphate-graphene oxide nano particles laden 3D-printed chitosan scaffolds with enhanced osteogenic potential and antibacterial properties

  Pahlevanzadeh, F., Emadi, R., Kharaziha, M., Poursamar, S. A., Nejatidanesh, F., Emadi, H., Aslani, R., Moroni, L. & Setayeshmehr, M., 1 Apr 2024, In: Biomaterials Advances. 158, 213760.

  Research output: Contribution to journal › Article › Academic › peer-review
  1 Downloads (Pure)

• Aprepitant Restores Corneal Sensitivity and Reduces Pain in DED

  Bonelli, F., Campestre, F., Lasagni Vitar, R. M., Demirsoy, I. H., Fonteyne, P. & Ferrari, G., 1 Feb 2024, In: Translational Vision Science & Technology. 13, 2, p. 9

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Automated, High-Throughput Phenotypic Screening and Analysis Platform to Study Pre- and Post-Implantation Morphogenesis in Stem Cell-Derived Embryo-Like Structures

  Shankar, V., van Blitterswijk, C., Vrij, E. & Giselbrecht, S., Jan 2024, In: Advanced Science. 11, 4, 16 p., 2304987.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Chondrogenesis of mesenchymal stromal cells on the 3D printed polycaprolactone/fibrin/decellular cartilage matrix hybrid scaffolds in the presence of piascledine

  Honarvar, A., Setayeshmehr, M., Ghaedamini, S., Hashemibeni, B., Moroni, L. & Karbasi, S., 2024, In: Journal of Biomaterials Science-Polymer Edition. 35, 6, p. 799-822 24 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Development of 4D-bioprinted shape-morphing magnetic constructs for cartilage regeneration using a silk fibroin-gelatin bioink

  Chakraborty, J., Fernández-Pérez, J., Takhsha Ghahfarokhi, M., van Kampen, K. A., ten Brink, T., Ramis, J., Kalogeropoulou, M., Cabassi, R., de Julián Fernández, C., Albertini, F., Mota, C., Ghosh, S. & Moroni, L., 20 Mar 2024, In: Cell Reports Physical Science. 5, 3, 22 p., 101819.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Development of Muscle Tendon Junction in vitro Using Aligned Electrospun PCL Fibres

  Iwasaki, N., Roldo, M., Karali, A., Sensini, A. & Blunn, G., 1 Jan 2024, (E-pub ahead of print) In: Engineered Regeneration.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Differential proteomics profile of microcapillary networks in response to sound pattern-driven local cell density enhancement

  Di Marzio, N., Tognato, R., Bella, E. D., De Giorgis, V., Manfredi, M., Cochis, A., Alini, M. & Serra, T., 1 Jun 2024, In: Biomaterials and Biosystems. 14, 100094.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Engineering Sensory Ganglion Multicellular System to Model Tissue Nerve Ingrowth

  Ma, J., Eglauf, J., Grad, S., Alini, M. & Serra, T., 20 Mar 2024, In: Advanced Science. 11, 11, 16 p., 2308478.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Full-field strain distribution in hierarchical electrospun nanofibrous poly-L(lactic) acid/collagen scaffolds for tendon and ligament regeneration: A multiscale study

  Sensini, A., Stamati, O., Marchiori, G., Sancisi, N., Gotti, C., Giavaresi, G., Cristofolini, L., Focarete, M. L., Zucchelli, A. & Tozzi, G., 15 Mar 2024, (E-pub ahead of print) In: Heliyon. 10, 5, e26796.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Human conjunctiva organoids to study ocular surface homeostasis and disease

  Bannier-Hélaouët, M., Korving, J., Ma, Z., Begthel, H., Giladi, A., Lamers, M. M., van de Wetering, W. J., Yawata, N., Yawata, M., LaPointe, V. L. S., Dickman, M. M., Kalmann, R., Imhoff, S. M., van Es, J. H., López-Iglesias, C., Peters, P. J., Haagmans, B. L., Wu, W. & Clevers, H., 1 Feb 2024, In: Cell Stem Cell. 31, 2, p. 227-243.e12

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Impression 3D et bioimpression pour la régénération osseuse en chirurgie orale

  Translated title of the contribution: Uses of 3D printing and Bioprinting for pre-implant bone reconstruction in Oral SurgeryCatros, S., Fenelon, M., De Oliveira, H., Shayya, G., Babilotte, J., Chassande, O. & Fricain, J-C., 1 Feb 2024, In: M S-Medecine Sciences. 40, 1, p. 92-97 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Improved on-tissue detection of the anti-cancer agent doxorubicin by quantitative matrix-assisted laser desorption/ionization mass spectrometry imaging

  Van Assche, C. X. L., Krüger, D. N., Flinders, B., Vandenbosch, M., Franssen, C., Guns, P. J. D., Heeren, R. M. A. & Cillero-Pastor, B., 1 May 2024, In: Talanta. 271, 9 p., 125667.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Introducing Dynamicity: Engineering Stress Relaxation Into Hydrogels Via Thiol-Ene Modified Alginate for Mechanobiological in vitro Modeling of the Cornea

  Feliciano, A. J., Grant, R., Fernandez-Perez, J., Giselbrecht, S. & Baker, M. B., Jan 2024, In: Macromolecular Bioscience. 24, 1, 18 p., 2300109.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Mass spectrometry imaging reveals flavor distribution in edible mushrooms

  Vats, M., Cillero-Pastor, B., Flinders, B., Cuypers, E. & Heeren, R. M. A., May 2024, In: Journal of Food Science and Technology-Mysore. 61, 5, p. 888-896 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Microfluidically Aligned Collagen to Maintain the Phenotype of Tenocytes In Vitro

  Giacomini, F., Baião Barata, D., Suk Rho, H., Tahmasebi Birgani, Z., van Blitterswijk, C., Giselbrecht, S., Truckenmüller, R. & Habibovic, P., 1 Mar 2024, In: Advanced Healthcare Materials. 13, 6, 18 p., 2303672.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Monochorionic Twinning in Bioengineered Human Embryo Models

  Luijkx, D. G., Ak, A., Guo, G., van Blitterswijk, C. A., Giselbrecht, S. & Vrij, E. J., 9 Apr 2024, (E-pub ahead of print) In: Advanced Materials. 2313306.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Multipotent adult progenitor cells prevent functional impairment and improve development in inflammation driven detriment of preterm ovine lungs

  Neuen, S. M. L., Ophelders, D. R. M. G., Widowski, H., Hütten, M. C., Brokken, T., van Gorp, C., Nikkels, P. G. J., Severens-Rijvers, C. A. H., Sthijns, M. M. J. P. E., van Blitterswijk, C. A., Troost, F. J., LaPointe, V. L. S., Jolani, S., Seiler, C., Pillow, J. J., Delhaas, T., Reynaert, N. L. & Wolfs, T. G. A. M., 1 Dec 2024, In: Regenerative Therapy. 27, p. 207-217 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Nanofunctionalized Microparticles for Glucose Delivery in Three-Dimensional Cell Assemblies

  Fois, M. G., Zengin, A., Song, K., Giselbrecht, S., Habibovic, P., Truckenmüller, R. K., van Rijt, S. & Tahmasebi Birgani, Z. N., 10 Apr 2024, In: ACS Applied Materials & Interfaces. 16, 14, p. 17347-17360 14 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Optimization of a tunable process for rapid production of calcium phosphate microparticles using a droplet-based microfluidic platform

  Alaoui Selsouli, Y., Rho, H. S., Eischen-Loges, M., Galván-Chacón, V. P., Stähli, C., Viecelli, Y., Döbelin, N., Bohner, M., Tahmasebi Birgani, Z. & Habibovic, P., 27 Mar 2024, In: Frontiers in bioengineering and biotechnology. 12, 1352184.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Purification of an Acidic Polysaccharide with Anticoagulant Activity from the Marine Sponge Sarcotragus spinosulus

  Nieddu, G., Obino, G., Ciampelli, C., Brunetti, A., Cubeddu, T., Manconi, R., Stocchino, G. A., Deiana, G. A., Formato, M. & Lepedda, A. J., 21 Mar 2024, In: Marine Drugs. 22, 3, 19 p., 139.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Scaffolds with a Tunable Nonlinear Elastic Region Using a Corrugated Design

  van Kampen, K. A., ten Brink, T., Mota, C. & Moroni, L., 1 Feb 2024, (E-pub ahead of print) In: Small Structures. 17 p., 2300399.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Spatial omics reveals molecular changes in focal cortical dysplasia type II

  Vermeulen, I., Rodriguez-Alvarez, N., François, L., Viot, D., Poosti, F., Aronica, E., Dedeurwaerdere, S., Barton, P., Cillero-Pastor, B. & Heeren, R. M. A., 2 Apr 2024, In: Neurobiology of Disease. 195, 106491.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Surgical suction filter-derived bone graft displays osteogenic miRNA and mRNA patterns

  Groven, R. V. M., Blokhuis, J. T., Poeze, M., van Griensven, M. & Blokhuis, T. J., Feb 2024, In: European Journal of Trauma and Emergency Surgery. 50, 1, p. 315-326 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• The role of plasma-induced surface chemistry on polycaprolactone nanofibers to direct chondrogenic differentiation of human mesenchymal stem cells

  Asadian, M., Tomasina, C., Onyshchenko, Y., Chan, K. V., Norouzi, M., Zonderland, J., Camarero-Espinosa, S., Morent, R., De Geyter, N. & Moroni, L., Feb 2024, In: Journal of Biomedical Materials Research Part A. 112, 2, p. 210 - 230 21 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• YAP mediates apoptosis through failed integrin adhesion reinforcement

  Shi, L., Nadjar-Boger, E., Jafarinia, H., Carlier, A. & Wolfenson, H., 21 Feb 2024, In: Cell Reports. 43, 3, 113811.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2023

  3D printed tubulointerstitium chip as an in vitro testing platform

  Addario, G., Eussen, D., Djudjaj, S., Boor, P., Moroni, L. & Mota, C., Dec 2023, (E-pub ahead of print) In: Macromolecular Bioscience. 12 p., 2300440.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Adipose-derived Stromal Cells Preserve Pancreatic Islet Function in A Transplantable 3d Bioprinted Scaffold

  Abadpour, S., Niemi, E. M., Orrhult, L. S., Hermanns, C., de Vries, R., Nogueira, L. P., Haugen, H. J., Josefsen, D., Krauss, S., Gatenholm, P., van Apeldoorn, A. & Scholz, H., Dec 2023, In: Advanced Healthcare Materials. 12, 32, 15 p., 2300640.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• A Humanized In Vitro Model of Innervated Skin for Transdermal Analgesic Testing

  Malheiro, A., Thon, M., Lourenço, A. F., Gamardo, A. S., Gibbs, S., Wieringa, P. & Moroni, L., Jan 2023, In: Macromolecular Bioscience. 23, 1, 11 p., e2200387.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File
  16 Downloads (Pure)

• A methodological approach towards the bio-inspired design of novel scaffolds for tissue engineering

  Fucile, P., Lamonaca, F., Gloria, A. & Moroni, L., 1 Dec 2023, In: Acta IMEKO. 12, 4, 47.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• An in vitro model system based on calcium- and phosphate ion-induced hMSC spheroid mineralization

  Vermeulen, S., Knoops, K., Duimel, H., Parvizifard, M., van Beurden, D., López-Iglesias, C., Giselbrecht, S., Truckenmüller, R., Habibovic, P. & Tahmasebi Birgani, Z., 1 Dec 2023, In: Materials today. Bio. 23, 1, 15 p., 100844.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• A potential osteogenic role for microRNA-181a-5p during palatogenesis

  Schoen, C., Bloemen, M., Carels, C. E. L., Verhaegh, G. W., Van Rheden, R., Roa, L. A., Glennon, J. C. & Von den Hoff, J. W., 18 Sept 2023, In: European Journal of Orthodontics. 45, 5, p. 575-583 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Arduino Automated Microwave Oven for Tissue Decalcification

  Savadori, P., Dalfino, S., Piazzoni, M., Inchingolo, F., Del Fabbro, M., Tartaglia, G. M. & Giardino, L., 1 Jan 2023, In: Bioengineering. 10, 1, 10 p., 79.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• A simplified method for detecting Gram-positive and Gram-negative bacteria in dental histological samples: A preliminary and comparative study

  Savadori, P., Dalfino, S., Piazzoni, M., Parrini, M., Del Fabbro, M., Tartaglia, G. M. & Giardino, L., 1 Jan 2023, In: Acta Histochemica. 125, 1, 7 p., 151992.

  Research output: Contribution to journal › Article › Academic › peer-review

• A single-cell RNA-seq analysis unravels the heterogeneity of primary cultured human corneal endothelial cells

  Català, P., Groen, N., LaPointe, V. L. S. & Dickman, M. M., 8 Jun 2023, In: Scientific Reports. 13, 1, 14 p., 9361.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Assessing the response of human primary macrophages to defined fibrous architectures fabricated by melt electrowriting

  Mondadori, C., Chandrakar, A., Lopa, S., Wieringa, P., Talò, G., Perego, S., Lombardi, G., Colombini, A., Moretti, M. & Moroni, L., Mar 2023, In: Bioactive Materials. 21, 1, p. 209-222 14 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Biodegradable Poly(ester) Urethane Acrylate Resins for Digital Light Processing: From Polymer Synthesis to 3D Printed Tissue Engineering Constructs

  Wang, R., Damanik, F., Kuhnt, T., Jaminon, A., Hafeez, S., Liu, H., Ippel, H., Dijkstra, P. J., Bouvy, N., Schurgers, L., ten Cate, A. T., Dias, A., Moroni, L. & Baker, M. B., 6 Jul 2023, In: Advanced Healthcare Materials. 12, 17, 13 p., 2202648.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Biofabrication of engineered dento-alveolar tissue

  EzEldeen, M., Moroni, L., Nejad, Z. M., Jacobs, R. & Mota, C., 1 May 2023, In: Biomaterials Advances. 148, 1, 15 p., 213371.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Bioprinting of Cardiac Tissue in Space: Where Are We?

  Tabury, K., Rehnberg, E., Baselet, B., Baatout, S. & Moroni, L., 1 Jun 2023, In: Advanced Healthcare Materials. 12, 23, 15 p., 2203338.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Bioprinting of Stem Cell Spheroids Followed by Post-Printing Chondrogenic Differentiation for Cartilage Tissue Engineering

  Decarli, M. C., Seijas-Gamardo, A., Morgan, F. L. C., Wieringa, P., Baker, M. B., Silva, J. V. L., Moraes, A. M., Moroni, L. & Mota, C., 27 Jul 2023, In: Advanced Healthcare Materials. 12, 19, 17 p., 2203021.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Cellular uptake of modified mRNA occurs via caveolae-mediated endocytosis, yielding high protein expression in slow-dividing cells

  Del Toro Runzer, C., Anand, S., Mota, C., Moroni, L., Plank, C., van Griensven, M. & Balmayor, E. R., 13 Jun 2023, In: Molecular Therapy - Nucleic Acids. 32, 1, p. 960-979 20 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Chitin nanofibrils modulate mechanical response in tympanic membrane replacements

  Anand, S., Azimi, B., Lucena, M., Ricci, C., Candito, M., Zavagna, L., Astolfi, L., Coltelli, M. B., Lazzeri, A., Berrettini, S., Moroni, L., Danti, S. & Mota, C., 15 Jun 2023, In: Carbohydrate Polymers. 310, 1, 120732.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Chitosan/polydopamine/octacalcium phosphate composite microcarrier simulates natural bone components to induce osteogenic differentiation of stem cells

  Liu, G., Ma, M., Yang, H., He, W., Xie, Y., Li, J., Li, J., Zhao, F. & Zheng, Y., 1 Nov 2023, In: Biomaterials Advances. 154, 1, 12 p., 213642.

  Research output: Contribution to journal › Article › Academic › peer-review

• Circulating miRNA expression in extracellular vesicles is associated with specific injuries after multiple trauma and surgical invasiveness

  Groven, R. V. M., Greven, J., Mert, Ü., Horst, K., Zhao, Q., Blokhuis, T. J., Huber-Lang, M., Hildebrand, F. & van Griensven, M., 23 Oct 2023, In: Frontiers in Immunology. 14, 1, 11 p., 1273612.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Coculture of adipose-derived mesenchymal stem cells/macrophages on decellularized placental sponge promotes differentiation into the osteogenic lineage

  Khosrowpour, Z., Hashemi, S. M., Mohammadi-Yeganeh, S., Moghtadaei, M., Brouki Milan, P., Moroni, L., Kundu, S. C. & Gholipourmalekabadi, M., Jan 2023, In: Artificial Organs. 47, 1, p. 47-61 15 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File
  115 Downloads (Pure)

• CODA: a combo-Seq data analysis workflow

  Nazzari, M., Hauser, D., van Herwijnen, M., Romitti, M., Carvalho, D. J., Kip, A. M. & Caiment, F., Jan 2023, In: Briefings in Bioinformatics. 24, 1, 14 p., bbac582.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Complementary Supramolecular Functionalization Enhances Antifouling Surfaces: A Ureidopyrimidinone-Functionalized Phosphorylcholine Polymer

  Feliciano, A. J., Soares, E., Bosman, A. W., van Blitterswijk, C., Moroni, L., LaPointe, V. L. S. & Baker, M. B., 6 Jul 2023, In: ACS Biomaterial Science and Engineering. 9, 8, p. 4619-4631 13 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Computational evidence for multi-layer crosstalk between the cadherin-11 and PDGFR pathways

  Karagöz, Z., Passanha, F. R., Robeerst, L., van Griensven, M., LaPointe, V. L. S. & Carlier, A., 22 Sept 2023, In: Scientific Reports. 13, 1, 12 p., 15804.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Decoupling the role of chemistry and microstructure in hMSCs response to an osteoinductive calcium phosphate ceramic

  Galván-Chacón, V. P., de Melo Pereira, D., Vermeulen, S., Yuan, H., Li, J. & Habibović, P., Jan 2023, In: Bioactive Materials. 19, 1, p. 127-138 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access