Automated multiscale vessel analysis for the quantification of MR angiography of peripheral arteriogenesis

Karolien Jaspers; Jos M. G. M. Slenter; Tim Leiner; Allard Wagenaar; Mark J. Post; Walter H. Backes

doi:10.1002/jmri.22819

Automated multiscale vessel analysis for the quantification of MR angiography of peripheral arteriogenesis

Karolien Jaspers, Jos M. G. M. Slenter, Tim Leiner, Allard Wagenaar, Mark J. Post, Walter H. Backes^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Purpose: To automatically analyze the time course of collateralization in a rat hindlimb ischemia model based on signal intensity distribution (SID). Materials and Methods: Time-of-flight magnetic resonance angiograms (TOF-MRA) were acquired in eight rats at 2, 7, and 21 days after unilateral femoral artery ligation. Analysis was performed on maximum intensity projections filtered with multiscale vessel enhancement filter. Differences in SID between ligated limb and a reference region were monitored over time and compared to manual collateral artery identification. Results: The differences in SID correlated well with the number of collateral arteries found with manual quantification. The time courses of ultrasmall (diameter

Original language	English
Pages (from-to)	379-386
Journal	Journal of Magnetic Resonance Imaging
Volume	35
Issue number	2
DOIs	https://doi.org/10.1002/jmri.22819
Publication status	Published - Feb 2012

Keywords

TOF-MRA
image filtering
collateral arteries
histogram analysis

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10.1002/jmri.22819

Cite this

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title = "Automated multiscale vessel analysis for the quantification of MR angiography of peripheral arteriogenesis",

abstract = "Purpose: To automatically analyze the time course of collateralization in a rat hindlimb ischemia model based on signal intensity distribution (SID). Materials and Methods: Time-of-flight magnetic resonance angiograms (TOF-MRA) were acquired in eight rats at 2, 7, and 21 days after unilateral femoral artery ligation. Analysis was performed on maximum intensity projections filtered with multiscale vessel enhancement filter. Differences in SID between ligated limb and a reference region were monitored over time and compared to manual collateral artery identification. Results: The differences in SID correlated well with the number of collateral arteries found with manual quantification. The time courses of ultrasmall (diameter ",

keywords = "TOF-MRA, image filtering, collateral arteries, histogram analysis",

author = "Karolien Jaspers and Slenter, {Jos M. G. M.} and Tim Leiner and Allard Wagenaar and Post, {Mark J.} and Backes, {Walter H.}",

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T1 - Automated multiscale vessel analysis for the quantification of MR angiography of peripheral arteriogenesis

AU - Jaspers, Karolien

AU - Slenter, Jos M. G. M.

AU - Leiner, Tim

AU - Wagenaar, Allard

AU - Post, Mark J.

AU - Backes, Walter H.

PY - 2012/2

Y1 - 2012/2

N2 - Purpose: To automatically analyze the time course of collateralization in a rat hindlimb ischemia model based on signal intensity distribution (SID). Materials and Methods: Time-of-flight magnetic resonance angiograms (TOF-MRA) were acquired in eight rats at 2, 7, and 21 days after unilateral femoral artery ligation. Analysis was performed on maximum intensity projections filtered with multiscale vessel enhancement filter. Differences in SID between ligated limb and a reference region were monitored over time and compared to manual collateral artery identification. Results: The differences in SID correlated well with the number of collateral arteries found with manual quantification. The time courses of ultrasmall (diameter

AB - Purpose: To automatically analyze the time course of collateralization in a rat hindlimb ischemia model based on signal intensity distribution (SID). Materials and Methods: Time-of-flight magnetic resonance angiograms (TOF-MRA) were acquired in eight rats at 2, 7, and 21 days after unilateral femoral artery ligation. Analysis was performed on maximum intensity projections filtered with multiscale vessel enhancement filter. Differences in SID between ligated limb and a reference region were monitored over time and compared to manual collateral artery identification. Results: The differences in SID correlated well with the number of collateral arteries found with manual quantification. The time courses of ultrasmall (diameter

KW - TOF-MRA

KW - image filtering

KW - collateral arteries

KW - histogram analysis

U2 - 10.1002/jmri.22819

DO - 10.1002/jmri.22819

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SP - 379

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JF - Journal of Magnetic Resonance Imaging

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