Do-(Not-)Mechanical-Circulatory-Support Orders: Should We Ask All Cardiac Surgery Patients for Informed Consent for Post-Cardiotomy Extracorporeal Life Circulatory Support?

J. Simons, M. Suverein, W. van Mook, K. Caliskan, O. Soliman, M. van de Poll, T. Delnoij, J. Maessen, B. Mees, R. Lorusso*

*Corresponding author for this work

Research output: Contribution to journal(Systematic) Review article peer-review

3 Citations (Web of Science)


Post-cardiotomy extracorporeal life support (PC-ECLS) has seen a substantial increase in use over the past 10 years. PC-ECLS can be a life-saving procedure and is mostly applied in the presence of unexpected, severe cardio-respiratory complication. Despite PC-ECLS being critical in allowing for organ recovery, it is unfortunately closely connected with an unpredictable outcomes, high morbidity, and, even in the case of cardiac function improvement, potential sustained disabilities that have a life-changing impact for the patient and his or her family. Since the decision to start PC-ECLS is made in an acute setting, there is often only limited or no time for self-determined choices. Due to the major impact of the intervention, it would be highly desirable to obtain informed consent before starting PC-ECLS, since the autonomy of the patient and shared-decision making are two of the most important ethical values in modern medicine. Recent developments regarding awareness of the impacts of a prolonged intensive care stay make this a particularly relevant topic. Therefore, it would be desirable to develop a structural strategy that takes into account the likelihood of such an intervention and the wishes and preferences of the patient, and thus the related autonomy of the patient. This article proposes key points for such a strategy in the form of a PC-ECLS informed consent, a do-(not-)mechanical-circulatory-support order (D(N)MCS), and specific guidelines to determine the extent of the shared decision making. The concept presented in this article could be a starting point for improved and ethical PC-ECLS treatment and application.
Original languageEnglish
Article number383
Number of pages12
JournalJournal of Clinical Medicine
Issue number3
Publication statusPublished - Jan 2021


  • cardiogenic-shock
  • complications
  • d(n)mcs
  • do-(not-)mechanical-circulatory-support
  • ecmo
  • els
  • ethics
  • experience
  • extracorporeal life support
  • long-term outcomes
  • membrane-oxygenation
  • mortality risk score
  • pc-ecls
  • post-cardiotomy extracorporeal life support
  • quality-of-life
  • resuscitation
  • survivors
  • ELS
  • D(N)MCS
  • ECMO

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