Differential brain activation patterns in adult attention-deficit hyperactivity disorder (ADHD) associated with task switching

P. Dibbets, E.A.T. Evers, P.P.M. Hurks, K. Bakker, J. Jolles

Research output: Contribution to journalArticleAcademicpeer-review

28 Citations (Scopus)

Abstract

Objective: The main aim of the study was to examine blood oxygen level dependent response during task switching in adults with attention-deficit/hyperactivity disorder (ADHD). Method: Fifteen male adults with ADHD and 14 controls participated and performed a task-switching paradigm. Results: Behaviorally, no specific executive control problems were observed in the ADHD participants, although they did display more errors in general. The neuroimaging data did show remarkable differences between the ADHD and control adults: Adults with ADHD engaged more strongly the dorsal anterior cingulate cortex, middle temporal gyrus, precuneus, lingual gyms, precentral gyrus, and insula than did the healthy controls during task switching. Controls displayed more task-related activity in the putamen, posterior cingulate gyrus, medial frontal gyrus, thalamus, orbitofrontal cortex, and postcentral gyrus. Conclusions: ADHD adults did not display specific executive control problems at a behavioral level, but did engage different brain areas during task switching compared with healthy controls. The results are discussed in the framework of the executive frontostriatal circuitry, conflict detection, and Intentional networks.

Original languageEnglish
Pages (from-to)413-423
Number of pages11
JournalNeuropsychology
Volume24
Issue number4
DOIs
Publication statusPublished - Jul 2010

Keywords

  • ANTERIOR CINGULATE CORTEX
  • CHILDREN
  • DEFICIT/HYPERACTIVITY DISORDER
  • EVENT-RELATED FMRI
  • FUNCTIONAL MRI
  • INTERFERENCE
  • LIFE-SPAN
  • RESPONSE-INHIBITION
  • VERBAL FLUENCY
  • WORKING-MEMORY
  • attention-deficit/hyperactivity disorder
  • executive control
  • frontostriatal circuitry
  • neuroimaging
  • task switching

Cite this

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title = "Differential brain activation patterns in adult attention-deficit hyperactivity disorder (ADHD) associated with task switching",
abstract = "Objective: The main aim of the study was to examine blood oxygen level dependent response during task switching in adults with attention-deficit/hyperactivity disorder (ADHD). Method: Fifteen male adults with ADHD and 14 controls participated and performed a task-switching paradigm. Results: Behaviorally, no specific executive control problems were observed in the ADHD participants, although they did display more errors in general. The neuroimaging data did show remarkable differences between the ADHD and control adults: Adults with ADHD engaged more strongly the dorsal anterior cingulate cortex, middle temporal gyrus, precuneus, lingual gyms, precentral gyrus, and insula than did the healthy controls during task switching. Controls displayed more task-related activity in the putamen, posterior cingulate gyrus, medial frontal gyrus, thalamus, orbitofrontal cortex, and postcentral gyrus. Conclusions: ADHD adults did not display specific executive control problems at a behavioral level, but did engage different brain areas during task switching compared with healthy controls. The results are discussed in the framework of the executive frontostriatal circuitry, conflict detection, and Intentional networks.",
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Differential brain activation patterns in adult attention-deficit hyperactivity disorder (ADHD) associated with task switching. / Dibbets, P.; Evers, E.A.T.; Hurks, P.P.M.; Bakker, K.; Jolles, J.

In: Neuropsychology, Vol. 24, No. 4, 07.2010, p. 413-423.

Research output: Contribution to journalArticleAcademicpeer-review

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AB - Objective: The main aim of the study was to examine blood oxygen level dependent response during task switching in adults with attention-deficit/hyperactivity disorder (ADHD). Method: Fifteen male adults with ADHD and 14 controls participated and performed a task-switching paradigm. Results: Behaviorally, no specific executive control problems were observed in the ADHD participants, although they did display more errors in general. The neuroimaging data did show remarkable differences between the ADHD and control adults: Adults with ADHD engaged more strongly the dorsal anterior cingulate cortex, middle temporal gyrus, precuneus, lingual gyms, precentral gyrus, and insula than did the healthy controls during task switching. Controls displayed more task-related activity in the putamen, posterior cingulate gyrus, medial frontal gyrus, thalamus, orbitofrontal cortex, and postcentral gyrus. Conclusions: ADHD adults did not display specific executive control problems at a behavioral level, but did engage different brain areas during task switching compared with healthy controls. The results are discussed in the framework of the executive frontostriatal circuitry, conflict detection, and Intentional networks.

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