TY - JOUR
T1 - Year-Round Respiratory Syncytial Virus Transmission in The Netherlands Following the COVID-19 Pandemic
T2 - A Prospective Nationwide Observational and Modeling Study
AU - Löwensteyn, Yvette N
AU - Zheng, Zhe
AU - Rave, Neele
AU - Bannier, Michiel A G E
AU - Billard, Marie-Noëlle
AU - Casalegno, Jean-Sebastien
AU - Pitzer, Virginia E
AU - Wildenbeest, Joanne G
AU - Weinberger, Daniel M
AU - Bont, Louis
AU - SPREAD study group
PY - 2023/8
Y1 - 2023/8
N2 - We initiated a nationwide prospective study to monitor RSV-related pediatric hospitalizations in 46 hospitals throughout the Netherlands between May 2021 - August 2022. We showed year-round RSV transmission in the Netherlands after an initial 2021 summer outbreak. The pattern was unprecedented and distinct from neighboring countries. We extended a dynamic simulation model to evaluate the impact of waning immunity on pediatric RSV hospitalizations in the Netherlands using four different scenarios. Our results suggest that the observed continuous RSV transmission pattern could be associated with waning immunity due to the period of very low RSV circulation during the COVID-19 pandemic.
AB - We initiated a nationwide prospective study to monitor RSV-related pediatric hospitalizations in 46 hospitals throughout the Netherlands between May 2021 - August 2022. We showed year-round RSV transmission in the Netherlands after an initial 2021 summer outbreak. The pattern was unprecedented and distinct from neighboring countries. We extended a dynamic simulation model to evaluate the impact of waning immunity on pediatric RSV hospitalizations in the Netherlands using four different scenarios. Our results suggest that the observed continuous RSV transmission pattern could be associated with waning immunity due to the period of very low RSV circulation during the COVID-19 pandemic.
KW - COVID-19
KW - Respiratory syncytial virus
KW - epidemic timing
KW - immunity debt
KW - seasonality
KW - transmission
KW - waning immunity
U2 - 10.1093/infdis/jiad282
DO - 10.1093/infdis/jiad282
M3 - Article
SN - 0022-1899
VL - 228
SP - 1394
EP - 1399
JO - Journal of Infectious Diseases
JF - Journal of Infectious Diseases
IS - 10
ER -