Vitamin K supplementation increases vitamin K tissue levels but fails to counteract ectopic calcification in a mouse model for pseudoxanthoma elasticum

Theo G. M. F. Gorgels; Jan H. Waarsing; Marjolein Herfs; Danielle Versteeg; Frank Schoensiegel; Toshiro Sato; Reinier O. Schlingemann; Boris Ivandic; Cees Vermeer; Leon J. Schurgers; Arthur A B Bergen

doi:10.1007/s00109-011-0782-y

Vitamin K supplementation increases vitamin K tissue levels but fails to counteract ectopic calcification in a mouse model for pseudoxanthoma elasticum

Theo G. M. F. Gorgels^*, Jan H. Waarsing, Marjolein Herfs, Danielle Versteeg, Frank Schoensiegel, Toshiro Sato, Reinier O. Schlingemann, Boris Ivandic, Cees Vermeer, Leon J. Schurgers, Arthur A B Bergen

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

30 Citations (Web of Science)

Original language	English
Pages (from-to)	1125-1135
Journal	Journal of Molecular Medicine
Volume	89
Issue number	11
DOIs	https://doi.org/10.1007/s00109-011-0782-y
Publication status	Published - Nov 2011

Keywords

Pseudoxanthoma elasticum
ABC transporter
Vitamin K
Ectopic calcification
Vascular calcification
Connective tissue
Cardiovascular
Vitamins
Calcium metabolism
Mouse models

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10.1007/s00109-011-0782-y

Cite this

Gorgels, T. G. M. F., Waarsing, J. H., Herfs, M., Versteeg, D., Schoensiegel, F., Sato, T., Schlingemann, R. O., Ivandic, B., Vermeer, C., Schurgers, L. J., & Bergen, A. A. B. (2011). Vitamin K supplementation increases vitamin K tissue levels but fails to counteract ectopic calcification in a mouse model for pseudoxanthoma elasticum. Journal of Molecular Medicine, 89(11), 1125-1135. https://doi.org/10.1007/s00109-011-0782-y

Gorgels, Theo G. M. F. ; Waarsing, Jan H. ; Herfs, Marjolein ; Versteeg, Danielle ; Schoensiegel, Frank ; Sato, Toshiro ; Schlingemann, Reinier O. ; Ivandic, Boris ; Vermeer, Cees ; Schurgers, Leon J. ; Bergen, Arthur A B. / Vitamin K supplementation increases vitamin K tissue levels but fails to counteract ectopic calcification in a mouse model for pseudoxanthoma elasticum. In: Journal of Molecular Medicine. 2011 ; Vol. 89, No. 11. pp. 1125-1135.

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title = "Vitamin K supplementation increases vitamin K tissue levels but fails to counteract ectopic calcification in a mouse model for pseudoxanthoma elasticum",

keywords = "Pseudoxanthoma elasticum, ABC transporter, Vitamin K, Ectopic calcification, Vascular calcification, Connective tissue, Cardiovascular, Vitamins, Calcium metabolism, Mouse models",

author = "Gorgels, {Theo G. M. F.} and Waarsing, {Jan H.} and Marjolein Herfs and Danielle Versteeg and Frank Schoensiegel and Toshiro Sato and Schlingemann, {Reinier O.} and Boris Ivandic and Cees Vermeer and Schurgers, {Leon J.} and Bergen, {Arthur A B}",

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Gorgels, TGMF, Waarsing, JH, Herfs, M, Versteeg, D, Schoensiegel, F, Sato, T, Schlingemann, RO, Ivandic, B, Vermeer, C , Schurgers, LJ & Bergen, AAB 2011, 'Vitamin K supplementation increases vitamin K tissue levels but fails to counteract ectopic calcification in a mouse model for pseudoxanthoma elasticum', Journal of Molecular Medicine, vol. 89, no. 11, pp. 1125-1135. https://doi.org/10.1007/s00109-011-0782-y

Vitamin K supplementation increases vitamin K tissue levels but fails to counteract ectopic calcification in a mouse model for pseudoxanthoma elasticum. / Gorgels, Theo G. M. F.; Waarsing, Jan H.; Herfs, Marjolein; Versteeg, Danielle; Schoensiegel, Frank; Sato, Toshiro; Schlingemann, Reinier O.; Ivandic, Boris; Vermeer, Cees ; Schurgers, Leon J.; Bergen, Arthur A B.

In: Journal of Molecular Medicine, Vol. 89, No. 11, 11.2011, p. 1125-1135.

Research output: Contribution to journal › Article › Academic › peer-review

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T1 - Vitamin K supplementation increases vitamin K tissue levels but fails to counteract ectopic calcification in a mouse model for pseudoxanthoma elasticum

AU - Gorgels, Theo G. M. F.

AU - Waarsing, Jan H.

AU - Herfs, Marjolein

AU - Versteeg, Danielle

AU - Schoensiegel, Frank

AU - Sato, Toshiro

AU - Schlingemann, Reinier O.

AU - Ivandic, Boris

AU - Vermeer, Cees

AU - Schurgers, Leon J.

AU - Bergen, Arthur A B

PY - 2011/11

Y1 - 2011/11

KW - Pseudoxanthoma elasticum

KW - ABC transporter

KW - Vitamin K

KW - Ectopic calcification

KW - Vascular calcification

KW - Connective tissue

KW - Cardiovascular

KW - Vitamins

KW - Calcium metabolism

KW - Mouse models

U2 - 10.1007/s00109-011-0782-y

DO - 10.1007/s00109-011-0782-y

M3 - Article

VL - 89

SP - 1125

EP - 1135

JO - Journal of Molecular Medicine

JF - Journal of Molecular Medicine

SN - 0946-2716

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ER -