Vitamin K supplementation increases vitamin K tissue levels but fails to counteract ectopic calcification in a mouse model for pseudoxanthoma elasticum

Theo G. M. F. Gorgels, Jan H. Waarsing, Marjolein Herfs, Danielle Versteeg, Frank Schoensiegel, Toshiro Sato, Reinier O. Schlingemann, Boris Ivandic, Cees Vermeer, Leon J. Schurgers, Arthur A B Bergen

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1125-1135
JournalJournal of Molecular Medicine
Volume89
Issue number11
DOIs
Publication statusPublished - Nov 2011

Keywords

  • Pseudoxanthoma elasticum
  • ABC transporter
  • Vitamin K
  • Ectopic calcification
  • Vascular calcification
  • Connective tissue
  • Cardiovascular
  • Vitamins
  • Calcium metabolism
  • Mouse models

Cite this

Gorgels, T. G. M. F., Waarsing, J. H., Herfs, M., Versteeg, D., Schoensiegel, F., Sato, T., Schlingemann, R. O., Ivandic, B., Vermeer, C., Schurgers, L. J., & Bergen, A. A. B. (2011). Vitamin K supplementation increases vitamin K tissue levels but fails to counteract ectopic calcification in a mouse model for pseudoxanthoma elasticum. Journal of Molecular Medicine, 89(11), 1125-1135. https://doi.org/10.1007/s00109-011-0782-y