Vascular CXCR4 Limits Atherosclerosis by Maintaining Arterial Integrity Evidence From Mouse and Human Studies

Yvonne Doring, Heidi Noels, Emiel P. C. van der Vorst, Carlos Neideck, Virginia Egea, Maik Drechsler, Manuela Mandl, Lukas Pawig, Yvonne Jansen, Katrin Schroeder, Kiril Bidzhekov, Remco T. A. Megens, Wendy Theelen, Barbara M. Klinkhammer, Peter Boor, Leon Schurgers, Rick van Gorp, Christian Ries, Pascal J. H. Kusters, Allard van der WalTilman M. Hackeng, Gabor Gaebel, Ralf P. Brandes, Oliver Soehnlein, Esther Lutgens, Dietmar Vestweber, Daniel Teupser, Lesca M. Holdt, Daniel J. Rader, Danish Saleheen, Christian Weber*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)388-403
Number of pages39
JournalCirculation
Volume136
Issue number4
DOIs
Publication statusPublished - 25 Jul 2017

Keywords

  • atherosclerosis
  • cadherins
  • endothelial cells
  • receptors, CXCR4
  • permeability
  • smooth muscle cell phenotype
  • WNT signaling pathway
  • SMOOTH-MUSCLE-CELLS
  • CHEMOKINE RECEPTOR CXCR4
  • MACROPHAGE-LIKE CELLS
  • E-DEFICIENT MICE
  • VE-CADHERIN
  • MYOCARDIAL-INFARCTION
  • CHOLESTEROL EFFLUX
  • PROMOTES ATHEROSCLEROSIS
  • NEOINTIMAL HYPERPLASIA
  • CARDIOVASCULAR-DISEASE

Cite this

Doring, Y., Noels, H., van der Vorst, E. P. C., Neideck, C., Egea, V., Drechsler, M., Mandl, M., Pawig, L., Jansen, Y., Schroeder, K., Bidzhekov, K., Megens, R. T. A., Theelen, W., Klinkhammer, B. M., Boor, P., Schurgers, L., van Gorp, R., Ries, C., Kusters, P. J. H., ... Weber, C. (2017). Vascular CXCR4 Limits Atherosclerosis by Maintaining Arterial Integrity Evidence From Mouse and Human Studies. Circulation, 136(4), 388-403. https://doi.org/10.1161/CIRCULATIONAHA.117.027646