Validation of an analytical method using HPLC-MS/MS to quantify osimertinib in human plasma and supplementary stability results

Ard van Veelen, Robin van Geel, Yvo de Beer, Anne-Marie Dingemans, Leo Stolk, Rob Ter Heine, Frank de Vries, Sander Croes

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article numbere4771
Number of pages9
JournalBiomedical Chromatography
Volume34
Issue number4
Early online date6 Dec 2019
DOIs
Publication statusPublished - Apr 2020

Keywords

  • AFATINIB
  • AZD9291
  • CANCER
  • CRIZOTINIB
  • EGFR INHIBITORS
  • KINASE INHIBITORS
  • MASS-SPECTROMETRIC ASSAY
  • PHARMACOKINETICS
  • QUANTIFICATION
  • analysis
  • osimertinib
  • room temperature
  • stability
  • validation

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