TY - JOUR
T1 - TRI-SCORE
T2 - a single-centre validation study
AU - Sala, Alessandra
AU - Carino, Davide
AU - Lorusso, Roberto
AU - Zancanaro, Edoardo
AU - Bargagna, Marta
AU - Del Forno, Benedetto
AU - Trumello, Cinzia
AU - Denti, Paolo
AU - Ruggeri, Stefania
AU - Nonis, Alessandro
AU - Scarale, Maria Giovanna
AU - Schiavi, Davide
AU - Castiglioni, Alessandro
AU - Maisano, Francesco
AU - Alfieri, Ottavio
AU - De Bonis, Michele
PY - 2023/6/1
Y1 - 2023/6/1
N2 - OBJECTIVES: The TRI-SCORE is a recently published risk score for predicting in-hospital mortality in patients undergoing isolated tricuspid valve surgery (ITVS). The aim of this study is to externally validate the ability of the TRI-SCORE in predicting in-hospital and long-term mortality following ITVS.METHODS: A retrospective review of our institutional database was carried out to identify all patients undergoing isolated tricuspid valve repair or replacement from March 1997 to March 2021. The TRI-SCORE was calculated for all patients. Discrimination of the TRI-SCORE was assessed using receiver operating characteristic curves. Accuracy of the models was tested calculating the Brier score. Finally, a COX regression was employed to evaluate the relationship between the TRI-SCORE value and long-term mortality.RESULTS: A total of 176 patients were identified and the median TRI-SCORE was 3 (1-5). The cut-off value identified for increased risk of isolated ITVS was 5. Regarding in-hospital outcomes, the TRI-SCORE showed high discrimination (area under the curve 0.82), and high accuracy (Brier score 0.054). This score showed also very good performance in predicting long-term mortality (at 10 years, hazard ratio: 1.47, 95% confidence interval [1.31-1.66], P < 0.001), with high discrimination (area under the curve >0.80 at 1-5 and 10 years) and high accuracy values (Brier score 0.179).CONCLUSIONS: This external validation confirms the good performance of the TRI-SCORE in predicting in-hospital mortality. Moreover, the score showed also very good performance in predicting the long-term mortality.
AB - OBJECTIVES: The TRI-SCORE is a recently published risk score for predicting in-hospital mortality in patients undergoing isolated tricuspid valve surgery (ITVS). The aim of this study is to externally validate the ability of the TRI-SCORE in predicting in-hospital and long-term mortality following ITVS.METHODS: A retrospective review of our institutional database was carried out to identify all patients undergoing isolated tricuspid valve repair or replacement from March 1997 to March 2021. The TRI-SCORE was calculated for all patients. Discrimination of the TRI-SCORE was assessed using receiver operating characteristic curves. Accuracy of the models was tested calculating the Brier score. Finally, a COX regression was employed to evaluate the relationship between the TRI-SCORE value and long-term mortality.RESULTS: A total of 176 patients were identified and the median TRI-SCORE was 3 (1-5). The cut-off value identified for increased risk of isolated ITVS was 5. Regarding in-hospital outcomes, the TRI-SCORE showed high discrimination (area under the curve 0.82), and high accuracy (Brier score 0.054). This score showed also very good performance in predicting long-term mortality (at 10 years, hazard ratio: 1.47, 95% confidence interval [1.31-1.66], P < 0.001), with high discrimination (area under the curve >0.80 at 1-5 and 10 years) and high accuracy values (Brier score 0.179).CONCLUSIONS: This external validation confirms the good performance of the TRI-SCORE in predicting in-hospital mortality. Moreover, the score showed also very good performance in predicting the long-term mortality.
KW - TRI-SCORE
KW - Risk scores
KW - Isolated tricuspid valve surgery
KW - Tricuspid regurgitation
KW - Tricuspid valve disease
KW - TRICUSPID REGURGITATION
KW - OUTCOMES
KW - SURGERY
KW - IMPACT
U2 - 10.1093/icvts/ivad085
DO - 10.1093/icvts/ivad085
M3 - Article
C2 - 37216902
SN - 2753-670X
VL - 36
JO - Interdisciplinary CardioVascular and Thoracic Surgery
JF - Interdisciplinary CardioVascular and Thoracic Surgery
IS - 6
M1 - ivad085
ER -