Trends in breast biopsies for abnormalities detected at screening mammography: a population-based study in the Netherlands

V. van Breest Smallenburg*, J. Nederend, A. C. Voogd, J. W. W. Coebergh, M. van Beek, F. H. Jansen, W. J. Louwman, L. E. M. Duijm

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

16 Citations (Web of Science)


Background: Diagnostic surgical breast biopsies have several disadvantages, therefore, they should be used with hesitation. We determined time trends in types of breast biopsies for the workup of abnormalities detected at screening mammography. We also examined diagnostic delays. Methods: In a Dutch breast cancer screening region 6230 women were referred for an abnormal screening mammogram between 1 January 1997 and 1 January 2011. During two year follow-up clinical data, breast imaging-, biopsy-, surgery-and pathology-reports were collected of these women. Furthermore, breast cancers diagnosed >3 months after referral (delays) were examined, this included review of mammograms and pathology specimens to determine the cause of the delays. Results: In 41.1% (1997-1998) and in 44.8% (2009-2010) of referred women imaging was sufficient for making the diagnosis (P
Original languageEnglish
Pages (from-to)242-248
JournalBritish Journal of Cancer
Issue number1
Publication statusPublished - 9 Jul 2013


  • breast cancer screening
  • referral
  • diagnostic workup
  • breast biopsy
  • trends

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